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The map label for this gene is mod [H]

Identifier: 158424882

GI number: 158424882

Start: 3758389

End: 3760119

Strand: Direct

Name: mod [H]

Synonym: AZC_3258

Alternate gene names: 158424882

Gene position: 3758389-3760119 (Clockwise)

Preceding gene: 158424881

Following gene: 158424883

Centisome position: 69.99

GC content: 55.46

Gene sequence:

>1731_bases
ATGACGGAGCTGAGTTTCAAGGGCAAAGAGTTTGTCTATAACCACCATCTGGCGGTGCCCTTCCGTCCGCTGGTGCCCGA
TGAAAGCAAGGGCATTGGCCCGGTTGCGCTCGACGGCAATCTCGTCGTTCACGGCGACAATCTGCACGCTCTGAAGGCGC
TCCTGCCGCTTTATGCGGGCAAGGTAGATTGCGTGTATATCGACCCGCCCTACAATACCGGCAAGAGCGATTGGTCATAT
AACGACAAAGTCAATTCGCCGGTGATTCAGGAATGGCTCGATAGCAATCCGATCACCGTCGATGACACGCTTCGGCATGA
CAAGTGGGCGTGCATGATGTGGCCGCGCCTTCAGCTCTTACGCGACCTCATGAAGCCGGGGGCAGTCATTTTTGCGAGCA
TCGACGATAACGAGGTCGCTCTGTTCAAGCATCTTCTGCACGCCACATTTGGCGACAATAACAATCCGAAAAGCAACCCT
CATCTTGGCACCATTATCTGGAAGAATGCGACAGATAATAATCCAACGAATATCGCAATTGAACATGAGTATGTTCATGT
ATTTTGCTTGGAGCGGGATGGCGTTGCACCTATCTGGAGTTCTCCGTGGTCGGACCTGAAAGATTGCCTTCTTGCGAAGG
AACAGGAGCTTTTGGCCGCTAACTTAAGCGATGATGAGCTTTCATCACAATATACGGAATGGTTTAGACTGCATAAGCCG
CAACTCGGCCCCTTGCAGGAGTATAATCAGATCGACCGGGGCGGGATTTTCACTGCCTCGCGAAGCGTCCACAACCCGGG
CCGTGAGGGTTATCGCTGGGATTTAATGAATCCCAAGACCCAGAAACTGGTGCCGCAACCGCTCATGGGATACCGCTTTC
CTGAAGACACCCGCGACGAGTTGCTTGCGCAGGACCGCATCATTTTCAGCGACGATCCCGATCAGCTCATCCGCCTCAAG
ACCTACGTGAAGGACTACAAGGAGAAGATGCCGGGGATCATTGAAATAGATGGTCGGCGCGGCGCGAATGAGCTGAAAAA
GATTTTCCCAGAGTCGAAGCAAGCCTTCAAGAATCCAAAGACCTACACGCTTATTGAGTGGCTTCTTTCATACACCGCTG
GCCCGGATGCTGTCGTTCTCGACTCATTTGCTGGCTCCGGAACGACGGCGCAGGCGGTCATGAAACTGAACGAGAGGGAT
GGCGGAAATCGGAAGTTTATCCTTGTCGAAATGGAAGATTATGCCGACGAACTGACGGCAGAGCGTGTTCGCCGCCTTAT
CCAGGGCGTTCCGACTTCAAAGGACGACGAGTATAAAACCGGCCTCGGCGGCACCTTCACCTATTGCACTCTCGGCGATC
CCGTGGAGCTGGATAAGGTGCTGAGCGGTGAAACCCTGCCGCCCTATGCCGGTCTCGGCGCGGCACTGTTCCACATGGCG
ACCAATCGCGCGCTCGATCCCGCAGCCGTGCGGGAGGATGATTTCTATCTCGGTGCCATAGAAGGCCAGCATGTCTGGCT
GATCTACAAGCCCGATCTCGACTGGCTGAAATCGCCGGAAGCGGCACTGACGCTGGCGCGCGCCAAGGCATTCGCCGCCT
CCGATCCGGACAAGCGGCACCTTGTCTTCGCCCCGGCGCGTTTCGTGAGCCAGAAGATGCTGGCGGAACAGAACATCCCT
GTGGAGTTCGTGCCGCTGCCCTTCGCGCTTTACCGCATAGACCGGAGCTGA

Upstream 100 bases:

>100_bases
TGATGCGCATGCAGAACAGCTACGACATTGCGCAGGCCCGCAGGCGGGAAGCGGAGATCAAGGTCGAGCGATACACAGGA
ATGAATACGAAGGGTCGAGC

Downstream 100 bases:

>100_bases
CGCCATGTTTCGCCAGCTCGATTATCAGGACCGCGTGCTCTCTACGCTCGATGCCTATCTCGACCTTTTGAAGGAGAAGA
AAGCACGTGCAGACAAGGTG

Product: DNA methylase

Products: NA

Alternate protein names: M.EcoP15I; EcoP15I methyltransferase [H]

Number of amino acids: Translated: 576; Mature: 575

Protein sequence:

>576_residues
MTELSFKGKEFVYNHHLAVPFRPLVPDESKGIGPVALDGNLVVHGDNLHALKALLPLYAGKVDCVYIDPPYNTGKSDWSY
NDKVNSPVIQEWLDSNPITVDDTLRHDKWACMMWPRLQLLRDLMKPGAVIFASIDDNEVALFKHLLHATFGDNNNPKSNP
HLGTIIWKNATDNNPTNIAIEHEYVHVFCLERDGVAPIWSSPWSDLKDCLLAKEQELLAANLSDDELSSQYTEWFRLHKP
QLGPLQEYNQIDRGGIFTASRSVHNPGREGYRWDLMNPKTQKLVPQPLMGYRFPEDTRDELLAQDRIIFSDDPDQLIRLK
TYVKDYKEKMPGIIEIDGRRGANELKKIFPESKQAFKNPKTYTLIEWLLSYTAGPDAVVLDSFAGSGTTAQAVMKLNERD
GGNRKFILVEMEDYADELTAERVRRLIQGVPTSKDDEYKTGLGGTFTYCTLGDPVELDKVLSGETLPPYAGLGAALFHMA
TNRALDPAAVREDDFYLGAIEGQHVWLIYKPDLDWLKSPEAALTLARAKAFAASDPDKRHLVFAPARFVSQKMLAEQNIP
VEFVPLPFALYRIDRS

Sequences:

>Translated_576_residues
MTELSFKGKEFVYNHHLAVPFRPLVPDESKGIGPVALDGNLVVHGDNLHALKALLPLYAGKVDCVYIDPPYNTGKSDWSY
NDKVNSPVIQEWLDSNPITVDDTLRHDKWACMMWPRLQLLRDLMKPGAVIFASIDDNEVALFKHLLHATFGDNNNPKSNP
HLGTIIWKNATDNNPTNIAIEHEYVHVFCLERDGVAPIWSSPWSDLKDCLLAKEQELLAANLSDDELSSQYTEWFRLHKP
QLGPLQEYNQIDRGGIFTASRSVHNPGREGYRWDLMNPKTQKLVPQPLMGYRFPEDTRDELLAQDRIIFSDDPDQLIRLK
TYVKDYKEKMPGIIEIDGRRGANELKKIFPESKQAFKNPKTYTLIEWLLSYTAGPDAVVLDSFAGSGTTAQAVMKLNERD
GGNRKFILVEMEDYADELTAERVRRLIQGVPTSKDDEYKTGLGGTFTYCTLGDPVELDKVLSGETLPPYAGLGAALFHMA
TNRALDPAAVREDDFYLGAIEGQHVWLIYKPDLDWLKSPEAALTLARAKAFAASDPDKRHLVFAPARFVSQKMLAEQNIP
VEFVPLPFALYRIDRS
>Mature_575_residues
TELSFKGKEFVYNHHLAVPFRPLVPDESKGIGPVALDGNLVVHGDNLHALKALLPLYAGKVDCVYIDPPYNTGKSDWSYN
DKVNSPVIQEWLDSNPITVDDTLRHDKWACMMWPRLQLLRDLMKPGAVIFASIDDNEVALFKHLLHATFGDNNNPKSNPH
LGTIIWKNATDNNPTNIAIEHEYVHVFCLERDGVAPIWSSPWSDLKDCLLAKEQELLAANLSDDELSSQYTEWFRLHKPQ
LGPLQEYNQIDRGGIFTASRSVHNPGREGYRWDLMNPKTQKLVPQPLMGYRFPEDTRDELLAQDRIIFSDDPDQLIRLKT
YVKDYKEKMPGIIEIDGRRGANELKKIFPESKQAFKNPKTYTLIEWLLSYTAGPDAVVLDSFAGSGTTAQAVMKLNERDG
GNRKFILVEMEDYADELTAERVRRLIQGVPTSKDDEYKTGLGGTFTYCTLGDPVELDKVLSGETLPPYAGLGAALFHMAT
NRALDPAAVREDDFYLGAIEGQHVWLIYKPDLDWLKSPEAALTLARAKAFAASDPDKRHLVFAPARFVSQKMLAEQNIPV
EFVPLPFALYRIDRS

Specific function: Binds the system-specific DNA recognition site 5'- CAGCAC-3'. Necessary for both restriction and methylation (of one of the two A's) [H]

COG id: COG2189

COG function: function code L; Adenine specific DNA methylase Mod

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002295
- InterPro:   IPR002941
- InterPro:   IPR002052 [H]

Pfam domain/function: PF01555 N6_N4_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 65042; Mature: 64910

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00092 N6_MTASE ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELSFKGKEFVYNHHLAVPFRPLVPDESKGIGPVALDGNLVVHGDNLHALKALLPLYAG
CCCCCCCCCEEEEECEEECCCCCCCCCCCCCCCCEEECCEEEEECCCHHHHHHHHHHHCC
KVDCVYIDPPYNTGKSDWSYNDKVNSPVIQEWLDSNPITVDDTLRHDKWACMMWPRLQLL
CEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEECCCCCCCCEEEEECHHHHHH
RDLMKPGAVIFASIDDNEVALFKHLLHATFGDNNNPKSNPHLGTIIWKNATDNNPTNIAI
HHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCEEEE
EHEYVHVFCLERDGVAPIWSSPWSDLKDCLLAKEQELLAANLSDDELSSQYTEWFRLHKP
EEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHCCC
QLGPLQEYNQIDRGGIFTASRSVHNPGREGYRWDLMNPKTQKLVPQPLMGYRFPEDTRDE
CCCCHHHHHCCCCCCEEEECCCCCCCCCCCCEEECCCCHHHHCCCCCHHCCCCCCCHHHH
LLAQDRIIFSDDPDQLIRLKTYVKDYKEKMPGIIEIDGRRGANELKKIFPESKQAFKNPK
HHHCCCEEECCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCHHHHHCCCC
TYTLIEWLLSYTAGPDAVVLDSFAGSGTTAQAVMKLNERDGGNRKFILVEMEDYADELTA
HHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHH
ERVRRLIQGVPTSKDDEYKTGLGGTFTYCTLGDPVELDKVLSGETLPPYAGLGAALFHMA
HHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCCHHHHHHHHHHH
TNRALDPAAVREDDFYLGAIEGQHVWLIYKPDLDWLKSPEAALTLARAKAFAASDPDKRH
HCCCCCCHHCCCCCEEEEEECCCEEEEEECCCCHHHCCCHHHHHHHHHHHHHCCCCCCCE
LVFAPARFVSQKMLAEQNIPVEFVPLPFALYRIDRS
EEEECHHHHHHHHHHHCCCCEEEECCCEEEEEECCC
>Mature Secondary Structure 
TELSFKGKEFVYNHHLAVPFRPLVPDESKGIGPVALDGNLVVHGDNLHALKALLPLYAG
CCCCCCCCEEEEECEEECCCCCCCCCCCCCCCCEEECCEEEEECCCHHHHHHHHHHHCC
KVDCVYIDPPYNTGKSDWSYNDKVNSPVIQEWLDSNPITVDDTLRHDKWACMMWPRLQLL
CEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEECCCCCCCCEEEEECHHHHHH
RDLMKPGAVIFASIDDNEVALFKHLLHATFGDNNNPKSNPHLGTIIWKNATDNNPTNIAI
HHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCEEEE
EHEYVHVFCLERDGVAPIWSSPWSDLKDCLLAKEQELLAANLSDDELSSQYTEWFRLHKP
EEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHCCC
QLGPLQEYNQIDRGGIFTASRSVHNPGREGYRWDLMNPKTQKLVPQPLMGYRFPEDTRDE
CCCCHHHHHCCCCCCEEEECCCCCCCCCCCCEEECCCCHHHHCCCCCHHCCCCCCCHHHH
LLAQDRIIFSDDPDQLIRLKTYVKDYKEKMPGIIEIDGRRGANELKKIFPESKQAFKNPK
HHHCCCEEECCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCHHHHHCCCC
TYTLIEWLLSYTAGPDAVVLDSFAGSGTTAQAVMKLNERDGGNRKFILVEMEDYADELTA
HHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHH
ERVRRLIQGVPTSKDDEYKTGLGGTFTYCTLGDPVELDKVLSGETLPPYAGLGAALFHMA
HHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCCHHHHHHHHHHH
TNRALDPAAVREDDFYLGAIEGQHVWLIYKPDLDWLKSPEAALTLARAKAFAASDPDKRH
HCCCCCCHHCCCCCEEEEEECCCEEEEEECCCCHHHCCCHHHHHHHHHHHHHCCCCCCCE
LVFAPARFVSQKMLAEQNIPVEFVPLPFALYRIDRS
EEEECHHHHHHHHHHHCCCCEEEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2837577 [H]