BacMap

Definition	Azorhizobium caulinodans ORS 571, complete genome.
Accession	NC_009937
Length	5,369,772

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The map label for this gene is bdhA [H]

Identifier: 158424835

GI number: 158424835

Start: 3675748

End: 3676527

Strand: Reverse

Name: bdhA [H]

Synonym: AZC_3211

Alternate gene names: 158424835

Gene position: 3676527-3675748 (Counterclockwise)

Preceding gene: 158424836

Following gene: 158424834

Centisome position: 68.47

GC content: 67.44

Gene sequence:

>780_bases
ATGAAGGGACGCAACGCCGTCGTCACCGGGTCCACGTCCGGCATCGGGCTCGCGATTGCAAGGTCACTTGCCGCCGAAGG
CTGCAACGTGATGCTCAACGGCTTCGGAGAACCCGCCCAGATCGAAATGGTCCGCCGTGAGATGGCCGAAACCACGGGAT
GCACCATCGGCTACTCCGGCGCGGACATGGGACGTCCGGAGGAGGTCCGCGCCCTCATTGCGGCGGCGCAGAACACGCTC
GGGACCGTCGATATCCTGATCAACAATGCCGGCGTGCAGCATGTGGCGCCCCTCGTCGCGTTCCCGGAGGACAAATGGGA
CCTGCTGCTGGCCGTCAACCTCTCGGCCGCCTTCCACGCCACCAAGGCGGTAATGCCGGCCATGCTTGCGCGCGGCTTCG
GCAGGGTCGTGAACATCGCCTCCGCTCTGGGGCTGGTGGGCGCGCCGCATAAGCCCGCCTATGTGGCCACGAAGCACGGC
CTCATCGGGCTCACCCGGTCCGTCGCGCTCGAGGTGGCACAGGGCGGGGTGACCTGCAACGTCGTGTGCCCCGGCATGGT
CATGACCCCCATCATCGAGATGCAGGTGGCGGATCAGGCGCGCGTCACCGGCCTGCCGCCCGAGGAAGTGGTGCGGGAGG
TGTTCCTTGAAAACCAACCCATCCGGCGTCCGGTCAAGGCGGAGGAGATCGCGGCGGCGGTTGTCTTCCTCTGCTCGGAG
GCGGCGGCCGGGATCACCGGAACCGTGCTCTCGGTGGACGGAGGCTATACCGCGCGGTGA

Upstream 100 bases:

>100_bases
GCTTTCGTGAATGGAATGCCGAGAGCGCCCGGACGGTGCGCGAGGCCCTCGCGCGGCATCTCGCGCAGACGTTCTGACCG
TCCATACAGGGAAGACACGC

Downstream 100 bases:

>100_bases
CGGGCGCACGTCGTGGATAGACGATCAACAAAAAGACACTCAGGGAGAAGCCACATGAAGGGTATCGTTCTCGCGGCGGC
GCTCGGCGTCGTCATGGGCG

Product: 3-hydroxybutyrate dehydrogenase precursor

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MKGRNAVVTGSTSGIGLAIARSLAAEGCNVMLNGFGEPAQIEMVRREMAETTGCTIGYSGADMGRPEEVRALIAAAQNTL
GTVDILINNAGVQHVAPLVAFPEDKWDLLLAVNLSAAFHATKAVMPAMLARGFGRVVNIASALGLVGAPHKPAYVATKHG
LIGLTRSVALEVAQGGVTCNVVCPGMVMTPIIEMQVADQARVTGLPPEEVVREVFLENQPIRRPVKAEEIAAAVVFLCSE
AAAGITGTVLSVDGGYTAR

Sequences:

>Translated_259_residues
MKGRNAVVTGSTSGIGLAIARSLAAEGCNVMLNGFGEPAQIEMVRREMAETTGCTIGYSGADMGRPEEVRALIAAAQNTL
GTVDILINNAGVQHVAPLVAFPEDKWDLLLAVNLSAAFHATKAVMPAMLARGFGRVVNIASALGLVGAPHKPAYVATKHG
LIGLTRSVALEVAQGGVTCNVVCPGMVMTPIIEMQVADQARVTGLPPEEVVREVFLENQPIRRPVKAEEIAAAVVFLCSE
AAAGITGTVLSVDGGYTAR
>Mature_259_residues
MKGRNAVVTGSTSGIGLAIARSLAAEGCNVMLNGFGEPAQIEMVRREMAETTGCTIGYSGADMGRPEEVRALIAAAQNTL
GTVDILINNAGVQHVAPLVAFPEDKWDLLLAVNLSAAFHATKAVMPAMLARGFGRVVNIASALGLVGAPHKPAYVATKHG
LIGLTRSVALEVAQGGVTCNVVCPGMVMTPIIEMQVADQARVTGLPPEEVVREVFLENQPIRRPVKAEEIAAAVVFLCSE
AAAGITGTVLSVDGGYTAR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=34.1176470588235, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI66933014, Length=181, Percent_Identity=37.5690607734807, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=32.5581395348837, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI5031737, Length=267, Percent_Identity=32.9588014981273, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI19923817, Length=264, Percent_Identity=28.7878787878788, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI126723750, Length=260, Percent_Identity=30.3846153846154, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=30.241935483871, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI4504505, Length=273, Percent_Identity=25.6410256410256, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=31.5, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI7705925, Length=260, Percent_Identity=28.0769230769231, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI33667109, Length=197, Percent_Identity=35.0253807106599, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI59889578, Length=198, Percent_Identity=33.8383838383838, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI126723191, Length=178, Percent_Identity=33.7078651685393, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI226371731, Length=192, Percent_Identity=32.8125, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI7706318, Length=203, Percent_Identity=29.064039408867, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI142976729, Length=215, Percent_Identity=28.3720930232558, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI20149619, Length=233, Percent_Identity=29.6137339055794, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI40807363, Length=195, Percent_Identity=29.7435897435897, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI10190704, Length=255, Percent_Identity=27.0588235294118, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI25282469, Length=132, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7657478, Length=223, Percent_Identity=29.5964125560538, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI224922801, Length=174, Percent_Identity=29.8850574712644, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI223718074, Length=211, Percent_Identity=31.7535545023697, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI210032110, Length=196, Percent_Identity=26.0204081632653, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4503817, Length=196, Percent_Identity=29.0816326530612, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4758504, Length=208, Percent_Identity=27.4038461538462, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI109715829, Length=253, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI210032112, Length=120, Percent_Identity=30, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI87082100, Length=262, Percent_Identity=35.8778625954198, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1787335, Length=259, Percent_Identity=35.5212355212355, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI87082160, Length=263, Percent_Identity=34.2205323193916, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI1789208, Length=265, Percent_Identity=31.3207547169811, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=30.078125, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=33.596837944664, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1789057, Length=253, Percent_Identity=29.2490118577075, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1789378, Length=258, Percent_Identity=27.906976744186, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787905, Length=255, Percent_Identity=28.6274509803922, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1786701, Length=243, Percent_Identity=30.0411522633745, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786812, Length=267, Percent_Identity=30.7116104868914, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI2367175, Length=255, Percent_Identity=28.6274509803922, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI2367365, Length=261, Percent_Identity=27.2030651340996, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI25147288, Length=261, Percent_Identity=32.183908045977, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17560676, Length=263, Percent_Identity=31.5589353612167, Blast_Score=118, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17555706, Length=261, Percent_Identity=31.4176245210728, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=30.9803921568627, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=29.6875, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17561402, Length=263, Percent_Identity=28.5171102661597, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17568967, Length=216, Percent_Identity=31.4814814814815, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17564282, Length=259, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17508895, Length=193, Percent_Identity=27.979274611399, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193203115, Length=195, Percent_Identity=29.7435897435897, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=274, Percent_Identity=27.7372262773723, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193203117, Length=193, Percent_Identity=30.0518134715026, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=30.6513409961686, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=275, Percent_Identity=27.6363636363636, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=260, Percent_Identity=30, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=271, Percent_Identity=28.4132841328413, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=29.3893129770992, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=271, Percent_Identity=28.4132841328413, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=270, Percent_Identity=27.4074074074074, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=271, Percent_Identity=28.4132841328413, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=277, Percent_Identity=27.7978339350181, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=285, Percent_Identity=27.3684210526316, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=279, Percent_Identity=27.5985663082437, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=275, Percent_Identity=26.9090909090909, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=28.4090909090909, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17560176, Length=193, Percent_Identity=30.5699481865285, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=277, Percent_Identity=27.4368231046931, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=271, Percent_Identity=28.0442804428044, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=273, Percent_Identity=27.1062271062271, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=273, Percent_Identity=27.4725274725275, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=203, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=29.1666666666667, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=22.9571984435798, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320089, Length=198, Percent_Identity=28.2828282828283, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=254, Percent_Identity=23.6220472440945, Blast_Score=62, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24644339, Length=263, Percent_Identity=31.1787072243346, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI28571526, Length=262, Percent_Identity=31.6793893129771, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21355319, Length=262, Percent_Identity=29.7709923664122, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21357041, Length=262, Percent_Identity=30.5343511450382, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=33.0677290836653, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI18859837, Length=243, Percent_Identity=31.2757201646091, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24639444, Length=258, Percent_Identity=28.6821705426357, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI161076933, Length=205, Percent_Identity=35.1219512195122, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24584748, Length=205, Percent_Identity=35.1219512195122, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24584744, Length=194, Percent_Identity=31.9587628865979, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI28574402, Length=194, Percent_Identity=31.9587628865979, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21355631, Length=173, Percent_Identity=31.7919075144509, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24643142, Length=257, Percent_Identity=26.8482490272374, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21358495, Length=202, Percent_Identity=27.7227722772277, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI221331218, Length=197, Percent_Identity=31.4720812182741, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24665243, Length=197, Percent_Identity=31.4720812182741, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640442, Length=215, Percent_Identity=28.3720930232558, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24665247, Length=198, Percent_Identity=31.3131313131313, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221331216, Length=198, Percent_Identity=31.3131313131313, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281364892, Length=173, Percent_Identity=26.5895953757225, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21356301, Length=232, Percent_Identity=27.5862068965517, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24644337, Length=199, Percent_Identity=29.1457286432161, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI116007236, Length=245, Percent_Identity=28.9795918367347, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24640492, Length=193, Percent_Identity=25.3886010362694, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007238, Length=169, Percent_Identity=33.7278106508876, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17647419, Length=218, Percent_Identity=25.2293577981651, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI28571387, Length=202, Percent_Identity=26.7326732673267, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 26843; Mature: 26843

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGRNAVVTGSTSGIGLAIARSLAAEGCNVMLNGFGEPAQIEMVRREMAETTGCTIGYSG
CCCCCEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEECC
ADMGRPEEVRALIAAAQNTLGTVDILINNAGVQHVAPLVAFPEDKWDLLLAVNLSAAFHA
CCCCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHCCCCCCCEEEEEEECHHHHHH
TKAVMPAMLARGFGRVVNIASALGLVGAPHKPAYVATKHGLIGLTRSVALEVAQGGVTCN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCEEEE
VVCPGMVMTPIIEMQVADQARVTGLPPEEVVREVFLENQPIRRPVKAEEIAAAVVFLCSE
EECCCHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
AAAGITGTVLSVDGGYTAR
HCCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MKGRNAVVTGSTSGIGLAIARSLAAEGCNVMLNGFGEPAQIEMVRREMAETTGCTIGYSG
CCCCCEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEECC
ADMGRPEEVRALIAAAQNTLGTVDILINNAGVQHVAPLVAFPEDKWDLLLAVNLSAAFHA
CCCCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHCCCCCCCEEEEEEECHHHHHH
TKAVMPAMLARGFGRVVNIASALGLVGAPHKPAYVATKHGLIGLTRSVALEVAQGGVTCN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCEEEE
VVCPGMVMTPIIEMQVADQARVTGLPPEEVVREVFLENQPIRRPVKAEEIAAAVVFLCSE
EECCCHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
AAAGITGTVLSVDGGYTAR
HCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9922248; 11481431 [H]