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The map label for this gene is bphD [H]

Identifier: 158424770

GI number: 158424770

Start: 3600316

End: 3601635

Strand: Direct

Name: bphD [H]

Synonym: AZC_3146

Alternate gene names: 158424770

Gene position: 3600316-3601635 (Clockwise)

Preceding gene: 158424767

Following gene: 158424777

Centisome position: 67.05

GC content: 66.59

Gene sequence:

>1320_bases
TTGCGCCGCGCGCCGGCACGCTATCCGAAACATGTGAGAGAAGAAACGGCCAAAGGTCGCTTGCGGCCGGGCTTTCCGGA
GGCCATCGTTCGGGCGTGCCGGGACGCCCGTGTGGCGACGACCGGTTGCCCCTTTTCAGAACGCCGCCGCATCACTGGCG
TGTTCGACGCACCGGGAAAGGATTCCATGCGCGCCGCGCGACTTGCCCTCGCTTTGGCCCTGCTGGCTGCCCCAGCCGCC
GCCCAGGAAACGGTCAAGGACACCACGGTCAAAGACCCGACGGTCAAGGACCAGACCGTCAAGGATCAGGCCGTCAAGGA
CACCCCGAAGCACGCCGCGCCGTCCGAGACCGAGGCGCCCCGCCCCGATGGCGCGCCCGTCGTGCGGGCGTACGGGGCGG
AGTTGCAAGACTTCCCCTATCCCTATGAAGTGAAGCGGTTCGAGTTCGTCTCCCAGCGCAAGCCGCTTCAGATGACCTAT
ATGGACGTGAAGCCGGAGCAGCCGAACGGGCGCACCGTCGTCCTGCTCCATGGCAAGAACTTCTGCGGCGCCACGTGGGA
AGCCACCATGGCCGTGCTGCTGAAGGCCGGCTATCGCGTGGTCGCGCCGGACCAGATCGGCTTCTGCAAGTCGTCCAAGC
CCATGGGCTACCAGTTCTCGCTCTATCAGCTCGCCGCCAACACCAAGGCGCTGCTGGAGCAGATCGGCGTCGAGAAGCCC
ATCATCATGGGCCACTCCATGGGCGGCATGCTCGCCATGCGCTATGCCATCAGCTTTCCCGATGCGCTCTCCGGCCTCGT
CCTCGTGAACCCCATCGGGCTTGAGGACTGGCGCGCGGCCGGCATTCCGGCGCGCACCGTGGACCAGTGGTTCGCGGGCG
AGCTGCGGACCACCTTCGACAGCATCAAGGCCTACCAGCAGAAGACCTATTATGCGGGCAGCTGGTCGCCGGACTATGAC
CGCTGGGTCGCCATGCTGGCCGGCATGTACCAGGGCGACGGCAAGGCCGCCGTGGCGTGGGATCAGGCGCTCGCCTCCGA
CATGGTCTATGGCCAGCCGGTCGTCTACGAGCTCGGCAAGATCGGCGCCCCCACCCTGATGCTCATCGGCGAGAAGGACC
TCACCGCCATCGGCAAGGATGCCGCCCCGCCGGAGGTGCAGAAGAAGGTCGGCAATTACGCCAAGCTCGGCCCCGCCGCA
GCCGCCGCCATTCCGGACGCGAAGCTTGTCATGTTCCCCGATCTCGGCCACGCACCGCAGATGCAGGCACCGGATCGCTT
CCACGCGGCGCTGATGAAGGGCCTCGCGGACCTGAAGTGA

Upstream 100 bases:

>100_bases
AGAGCGAGCCTGCGGGGCGACCCCGAAGCGAGCACGAGCTGGACCCGGTCGTTCACGTCTGCGTAACCTCACCTCGACCA
AAACCAAAGCGCGCAACGCG

Downstream 100 bases:

>100_bases
GGTCCGCCGATCAGCGCCCGGGCTTGAACCGGGCGCGGATGCGCTGCTCCAGGTCCTCGCGCACCTGACGATAGGCGGCG
AGGCGCTGCTCGCGGTTTCC

Product: hydrolase

Products: NA

Alternate protein names: HOPDA hydrolase; 2,6-dioxo-6-phenylhexa-3-enoate hydrolase [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MRRAPARYPKHVREETAKGRLRPGFPEAIVRACRDARVATTGCPFSERRRITGVFDAPGKDSMRAARLALALALLAAPAA
AQETVKDTTVKDPTVKDQTVKDQAVKDTPKHAAPSETEAPRPDGAPVVRAYGAELQDFPYPYEVKRFEFVSQRKPLQMTY
MDVKPEQPNGRTVVLLHGKNFCGATWEATMAVLLKAGYRVVAPDQIGFCKSSKPMGYQFSLYQLAANTKALLEQIGVEKP
IIMGHSMGGMLAMRYAISFPDALSGLVLVNPIGLEDWRAAGIPARTVDQWFAGELRTTFDSIKAYQQKTYYAGSWSPDYD
RWVAMLAGMYQGDGKAAVAWDQALASDMVYGQPVVYELGKIGAPTLMLIGEKDLTAIGKDAAPPEVQKKVGNYAKLGPAA
AAAIPDAKLVMFPDLGHAPQMQAPDRFHAALMKGLADLK

Sequences:

>Translated_439_residues
MRRAPARYPKHVREETAKGRLRPGFPEAIVRACRDARVATTGCPFSERRRITGVFDAPGKDSMRAARLALALALLAAPAA
AQETVKDTTVKDPTVKDQTVKDQAVKDTPKHAAPSETEAPRPDGAPVVRAYGAELQDFPYPYEVKRFEFVSQRKPLQMTY
MDVKPEQPNGRTVVLLHGKNFCGATWEATMAVLLKAGYRVVAPDQIGFCKSSKPMGYQFSLYQLAANTKALLEQIGVEKP
IIMGHSMGGMLAMRYAISFPDALSGLVLVNPIGLEDWRAAGIPARTVDQWFAGELRTTFDSIKAYQQKTYYAGSWSPDYD
RWVAMLAGMYQGDGKAAVAWDQALASDMVYGQPVVYELGKIGAPTLMLIGEKDLTAIGKDAAPPEVQKKVGNYAKLGPAA
AAAIPDAKLVMFPDLGHAPQMQAPDRFHAALMKGLADLK
>Mature_439_residues
MRRAPARYPKHVREETAKGRLRPGFPEAIVRACRDARVATTGCPFSERRRITGVFDAPGKDSMRAARLALALALLAAPAA
AQETVKDTTVKDPTVKDQTVKDQAVKDTPKHAAPSETEAPRPDGAPVVRAYGAELQDFPYPYEVKRFEFVSQRKPLQMTY
MDVKPEQPNGRTVVLLHGKNFCGATWEATMAVLLKAGYRVVAPDQIGFCKSSKPMGYQFSLYQLAANTKALLEQIGVEKP
IIMGHSMGGMLAMRYAISFPDALSGLVLVNPIGLEDWRAAGIPARTVDQWFAGELRTTFDSIKAYQQKTYYAGSWSPDYD
RWVAMLAGMYQGDGKAAVAWDQALASDMVYGQPVVYELGKIGAPTLMLIGEKDLTAIGKDAAPPEVQKKVGNYAKLGPAA
AAAIPDAKLVMFPDLGHAPQMQAPDRFHAALMKGLADLK

Specific function: Catalyzes an unusual C-C bond hydrolysis of 2-hydroxy-6- oxo-6-phenylhexa-2,4-dienoic acid (HOPDA) to produce benzoic acid and 2-hydroxy-2,4-pentadienoic acid (HPD) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. BphD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639
- InterPro:   IPR017727 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.7.1.8 [H]

Molecular weight: Translated: 47846; Mature: 47846

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRAPARYPKHVREETAKGRLRPGFPEAIVRACRDARVATTGCPFSERRRITGVFDAPGK
CCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCEEECCCCHHHCCCEEEEECCCCC
DSMRAARLALALALLAAPAAAQETVKDTTVKDPTVKDQTVKDQAVKDTPKHAAPSETEAP
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCC
RPDGAPVVRAYGAELQDFPYPYEVKRFEFVSQRKPLQMTYMDVKPEQPNGRTVVLLHGKN
CCCCCCCHHHHCCCHHCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEECCC
FCGATWEATMAVLLKAGYRVVAPDQIGFCKSSKPMGYQFSLYQLAANTKALLEQIGVEKP
CCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCC
IIMGHSMGGMLAMRYAISFPDALSGLVLVNPIGLEDWRAAGIPARTVDQWFAGELRTTFD
EEEECCCCHHHHHHHHHCCCHHHCCEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHHHHH
SIKAYQQKTYYAGSWSPDYDRWVAMLAGMYQGDGKAAVAWDQALASDMVYGQPVVYELGK
HHHHHHHHEEECCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCHHHHHHHC
IGAPTLMLIGEKDLTAIGKDAAPPEVQKKVGNYAKLGPAAAAAIPDAKLVMFPDLGHAPQ
CCCCEEEEECCCCHHHCCCCCCCHHHHHHHCCHHHCCCHHHHHCCCCEEEEECCCCCCCC
MQAPDRFHAALMKGLADLK
CCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRRAPARYPKHVREETAKGRLRPGFPEAIVRACRDARVATTGCPFSERRRITGVFDAPGK
CCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCEEECCCCHHHCCCEEEEECCCCC
DSMRAARLALALALLAAPAAAQETVKDTTVKDPTVKDQTVKDQAVKDTPKHAAPSETEAP
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCC
RPDGAPVVRAYGAELQDFPYPYEVKRFEFVSQRKPLQMTYMDVKPEQPNGRTVVLLHGKN
CCCCCCCHHHHCCCHHCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEECCC
FCGATWEATMAVLLKAGYRVVAPDQIGFCKSSKPMGYQFSLYQLAANTKALLEQIGVEKP
CCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCC
IIMGHSMGGMLAMRYAISFPDALSGLVLVNPIGLEDWRAAGIPARTVDQWFAGELRTTFD
EEEECCCCHHHHHHHHHCCCHHHCCEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHHHHH
SIKAYQQKTYYAGSWSPDYDRWVAMLAGMYQGDGKAAVAWDQALASDMVYGQPVVYELGK
HHHHHHHHEEECCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCHHHHHHHC
IGAPTLMLIGEKDLTAIGKDAAPPEVQKKVGNYAKLGPAAAAAIPDAKLVMFPDLGHAPQ
CCCCEEEEECCCCHHHCCCCCCCHHHHHHHCCHHHCCCHHHHHCCCCEEEEECCCCCCCC
MQAPDRFHAALMKGLADLK
CCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8344527 [H]