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The map label for this gene is yhcS [C]

Identifier: 158424745

GI number: 158424745

Start: 3575685

End: 3576650

Strand: Direct

Name: yhcS [C]

Synonym: AZC_3121

Alternate gene names: 158424745

Gene position: 3575685-3576650 (Clockwise)

Preceding gene: 158424744

Following gene: 158424746

Centisome position: 66.59

GC content: 68.12

Gene sequence:

>966_bases
ATGTCGCGACTGGACGATGTCGAGGTGTTTCTGCGGGTCGTGGATCGCGGCAGCTTCAATGGCGCCGCCGAGCAGCTCGG
CCTGCCGCCCACCTCGGTCAGCCGCAAGGTGAAGGCGCTGGAAGACCGGCTGGGCGTCCAGCTCCTCCATCGCACCACCC
GGCGCGTCTGGCCGAGCGAGGCGGGGCAAGCCTATTATCAGAAGTGCGTCGATGCCATCGCCGCCCTCGACCATGCGGAT
GCCTCCATCCGCGCGCTGACGCAGGAGCCCGAGGGGCATCTGAAGGTCCTGCTTCCCCATTCCACCGGCATCCTCATCGT
GGAGCCGGAGCTGGCGAACTTCCGCCGCCGCTACCCCAAGGTCCAGTTGCACATCACGCTCGACAACCATCCGCTCGATC
TCATCGAGCACGGCTTCGACGTGGCGGTGCGCCTCGGACCGGTGCGCGATTCCAGCTACCACGTCCGCAACCTCGGATCG
CAGCAGCTCATCTTTCTGGCGAGTCCCGACTATCTCGACGAGTTCGGCCGGCCGAGCCATCCGCGCGAATTGGCGGACCA
CGACATCATCGCCGTGCGCACCTCCCCCGGCCCCCTCGTCTGGCAGCTCGACGGGCCGAGCGACAGCTTCGAGATGCGTG
TCAGCCCCGCCCTCGATACCAACGACGCCATCATGGCCGTGCGCCAGGCCTCCGGCGCCTGCGGCATCACCATGCTCTCG
CGCTGCATGTCGCGACGGCGCGTCGAGTCGGGTGAGCTCGAAGTGGTCCTGCCCGGCTGGCAGCGCCGAGACCCCGTCGA
GCAGGTCGCGATCTTCCCCGCCCGCGCGACGCTGGACCTGAAGGTGCGTGTGTTCGTGGACTTCCTCGTGGACGCCTACA
ACCGCTGGCAGGGCGAAGGTCCGACACGCGATGCCGATTGCGCGCGCCTGCCCGCTACCCCCGCGAAGGCCAAGACCGGC
ACCTGA

Upstream 100 bases:

>100_bases
GCACCACCAGCGGGCGAACCTATATTTCCAAGATAAGACGCAGCCAGCGAACCATCCGCGGAACTGCTGTTCCCGGCACC
TACCGGAAAGGGCCTGCCCC

Downstream 100 bases:

>100_bases
CGCACACCCACCCGGCGCCCTCCCCATAATTCACATGCGGCACCGTCCTCGCGCAGAGGACGGTGCCGACTCGGTTTCAG
GGGATGCCCCTCCGCCGGCT

Product: transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MSRLDDVEVFLRVVDRGSFNGAAEQLGLPPTSVSRKVKALEDRLGVQLLHRTTRRVWPSEAGQAYYQKCVDAIAALDHAD
ASIRALTQEPEGHLKVLLPHSTGILIVEPELANFRRRYPKVQLHITLDNHPLDLIEHGFDVAVRLGPVRDSSYHVRNLGS
QQLIFLASPDYLDEFGRPSHPRELADHDIIAVRTSPGPLVWQLDGPSDSFEMRVSPALDTNDAIMAVRQASGACGITMLS
RCMSRRRVESGELEVVLPGWQRRDPVEQVAIFPARATLDLKVRVFVDFLVDAYNRWQGEGPTRDADCARLPATPAKAKTG
T

Sequences:

>Translated_321_residues
MSRLDDVEVFLRVVDRGSFNGAAEQLGLPPTSVSRKVKALEDRLGVQLLHRTTRRVWPSEAGQAYYQKCVDAIAALDHAD
ASIRALTQEPEGHLKVLLPHSTGILIVEPELANFRRRYPKVQLHITLDNHPLDLIEHGFDVAVRLGPVRDSSYHVRNLGS
QQLIFLASPDYLDEFGRPSHPRELADHDIIAVRTSPGPLVWQLDGPSDSFEMRVSPALDTNDAIMAVRQASGACGITMLS
RCMSRRRVESGELEVVLPGWQRRDPVEQVAIFPARATLDLKVRVFVDFLVDAYNRWQGEGPTRDADCARLPATPAKAKTG
T
>Mature_320_residues
SRLDDVEVFLRVVDRGSFNGAAEQLGLPPTSVSRKVKALEDRLGVQLLHRTTRRVWPSEAGQAYYQKCVDAIAALDHADA
SIRALTQEPEGHLKVLLPHSTGILIVEPELANFRRRYPKVQLHITLDNHPLDLIEHGFDVAVRLGPVRDSSYHVRNLGSQ
QLIFLASPDYLDEFGRPSHPRELADHDIIAVRTSPGPLVWQLDGPSDSFEMRVSPALDTNDAIMAVRQASGACGITMLSR
CMSRRRVESGELEVVLPGWQRRDPVEQVAIFPARATLDLKVRVFVDFLVDAYNRWQGEGPTRDADCARLPATPAKAKTGT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=295, Percent_Identity=31.1864406779661, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI145693193, Length=300, Percent_Identity=29.6666666666667, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1786401, Length=304, Percent_Identity=31.5789473684211, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1787128, Length=288, Percent_Identity=27.4305555555556, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI87081978, Length=287, Percent_Identity=28.9198606271777, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789440, Length=287, Percent_Identity=26.4808362369338, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1787589, Length=270, Percent_Identity=27.037037037037, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788706, Length=259, Percent_Identity=26.2548262548263, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789173, Length=252, Percent_Identity=26.1904761904762, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786448, Length=283, Percent_Identity=22.9681978798587, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI145693105, Length=197, Percent_Identity=22.8426395939086, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788748, Length=152, Percent_Identity=30.9210526315789, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788481, Length=270, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1786713, Length=177, Percent_Identity=25.9887005649718, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787806, Length=152, Percent_Identity=28.2894736842105, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35704; Mature: 35573

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLDDVEVFLRVVDRGSFNGAAEQLGLPPTSVSRKVKALEDRLGVQLLHRTTRRVWPSE
CCCHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AGQAYYQKCVDAIAALDHADASIRALTQEPEGHLKVLLPHSTGILIVEPELANFRRRYPK
CHHHHHHHHHHHHHHHCCCCCHHEEECCCCCCCEEEEEECCCCEEEECCCHHHHHHHCCE
VQLHITLDNHPLDLIEHGFDVAVRLGPVRDSSYHVRNLGSQQLIFLASPDYLDEFGRPSH
EEEEEEECCCCHHHHHCCCEEEEEECCCCCCCHHHHCCCCCEEEEEECCHHHHHCCCCCC
PRELADHDIIAVRTSPGPLVWQLDGPSDSFEMRVSPALDTNDAIMAVRQASGACGITMLS
CHHHCCCCEEEEEECCCCEEEEECCCCCCEEEEEECCCCCCHHHEEEHHCCCCCHHHHHH
RCMSRRRVESGELEVVLPGWQRRDPVEQVAIFPARATLDLKVRVFVDFLVDAYNRWQGEG
HHHHHHCCCCCCEEEEECCCCCCCCHHHHEEECCCEEEEEEHHHHHHHHHHHHHHCCCCC
PTRDADCARLPATPAKAKTGT
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SRLDDVEVFLRVVDRGSFNGAAEQLGLPPTSVSRKVKALEDRLGVQLLHRTTRRVWPSE
CCHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AGQAYYQKCVDAIAALDHADASIRALTQEPEGHLKVLLPHSTGILIVEPELANFRRRYPK
CHHHHHHHHHHHHHHHCCCCCHHEEECCCCCCCEEEEEECCCCEEEECCCHHHHHHHCCE
VQLHITLDNHPLDLIEHGFDVAVRLGPVRDSSYHVRNLGSQQLIFLASPDYLDEFGRPSH
EEEEEEECCCCHHHHHCCCEEEEEECCCCCCCHHHHCCCCCEEEEEECCHHHHHCCCCCC
PRELADHDIIAVRTSPGPLVWQLDGPSDSFEMRVSPALDTNDAIMAVRQASGACGITMLS
CHHHCCCCEEEEEECCCCEEEEECCCCCCEEEEEECCCCCCHHHEEEHHCCCCCHHHHHH
RCMSRRRVESGELEVVLPGWQRRDPVEQVAIFPARATLDLKVRVFVDFLVDAYNRWQGEG
HHHHHHCCCCCCEEEEECCCCCCCCHHHHEEECCCEEEEEEHHHHHHHHHHHHHHCCCCC
PTRDADCARLPATPAKAKTGT
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]