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The map label for this gene is hflX [H]

Identifier: 158424703

GI number: 158424703

Start: 3520601

End: 3521980

Strand: Reverse

Name: hflX [H]

Synonym: AZC_3079

Alternate gene names: 158424703

Gene position: 3521980-3520601 (Counterclockwise)

Preceding gene: 158424704

Following gene: 158424702

Centisome position: 65.59

GC content: 68.99

Gene sequence:

>1380_bases
GTGGAGCTTAAGGGACCGCGGGGCGCAGCGGGGGGTGGACTGAAGGGCGTGGACCGTCACGCTCCGCCCACCCGTTGTGC
CGTCATTACCCCACAGGTGACCAAGCGCGGGGCGCGCGCCGGTGCAGACCGGCGCAGCCCCGAGGCGCGTCTGGAGGAGG
CGGTGGGCCTTGCCGCCGCCATCGACCTCGACGTCGTGTATAAGGGCCTTGTCCTCATCTCCGAGGTGAAGCCGGCCACC
TATATCGGCTCCGGCAAGGTCGAGGAGATCGCGGGCATCGTTGCGGCGGAGGAGGTCGGCCTCGTCTTCGTCGATGCGGC
CCTGTCGCCCGTCCAGCAGCGCAATCTCGAGAAGGCGTGGTCCGCAAAGGTGGTGGACCGCACGGCCCTGATTCTCGAAA
TCTTCGGCAGTCGTGCCCGCACCAAGGAAGGCACGCTTCAGGTGGAACTCGCCCACCTGAACTACCAGCGTTCGCGCCTC
GTGCGGTCCTGGACCCATCTGGAGCGCCAGCGCGGCGGCTTCGGCTTCCTCGGCGGCCCCGGCGAGACCCAGATCGAGGC
GGATCGTCGGCAGATCGGCGAGCGCATCATCCGCATCGAGCGTGAACTGGAGCAGGTGAAGCGCACCCGCGCTCTCCACC
GTACCAGCCGCAAGCGCGTGCCTTATCCGGTGGTGGCGCTCGTCGGCTACACCAATGCCGGCAAGTCCACCCTGTTCAAC
CGGCTGACGCAGGCCGAGGTGATGGCACAGGATCTCCTGTTCGCCACCCTCGATCCGACCTTGCGCGCCGTCGACCTGCC
CCATGGCACGCGCGTCATCCTGTCCGACACGGTGGGCTTCATCTCCGAGTTGCCGACGCAACTCGTCGCCGCCTTCCGCG
CCACGCTGGAAGAGGTGATCGAGGCGGACGTGATCCTGCACGTGCGTGACATCTCCCACCCCGACACCGATGCCCAGGCG
GCGGACGTGAAGGACGTGCTGACCGAACTCGGCATCGACGTCGAGGCCGGCGGCCGGCTGGTGGAGGTCTGGAACAAGAT
CGACATCCTGCCTGAGGCGGAGCGCGAGCAACTCCTGAACACGGCCGCGCGCGCGGAGCCGGAAGCACGCCCCGAGCTCG
TCTCGGCGTTGACCGGGGAGGGCGCGCCGGCCTTGCTCGACCGCATCGAAGCCCACGTCACGGCCGGCCGCACGCTGCTG
TCTGTGACGCTGGCGGCGGAGGACGGCGAGGGGCTCGGCTGGCTCTATCGGCATGGTGAGGTGCTGGAGCGGGAGAGCGG
TGCGGACGGCCATGTGGTGGTCTCGCTGCGCATCCTCCCCGAGCGGGTGGACCTCGTGAAACGCCGCTTCGGCGCGGCTC
AGGTCCGCGGCGAGGACTGA

Upstream 100 bases:

>100_bases
ATTGGTCTACAAGCACGCTATCTCCACGATCATGCCCGGGCATCCGGTGCAACTGTTTGATCCCACCGACGAGGTGGCTT
CGGAGAAAGCGTGATCCGGC

Downstream 100 bases:

>100_bases
GGCGTCCCGCGCCGCCGTGGCGCTTGCCTCCACGGTATCGGGCGTGTCCTATGCGACGCGTCATGATGCTGTTGGGGGCG
TCCTTGCCGAGTTCAACTGT

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MELKGPRGAAGGGLKGVDRHAPPTRCAVITPQVTKRGARAGADRRSPEARLEEAVGLAAAIDLDVVYKGLVLISEVKPAT
YIGSGKVEEIAGIVAAEEVGLVFVDAALSPVQQRNLEKAWSAKVVDRTALILEIFGSRARTKEGTLQVELAHLNYQRSRL
VRSWTHLERQRGGFGFLGGPGETQIEADRRQIGERIIRIERELEQVKRTRALHRTSRKRVPYPVVALVGYTNAGKSTLFN
RLTQAEVMAQDLLFATLDPTLRAVDLPHGTRVILSDTVGFISELPTQLVAAFRATLEEVIEADVILHVRDISHPDTDAQA
ADVKDVLTELGIDVEAGGRLVEVWNKIDILPEAEREQLLNTAARAEPEARPELVSALTGEGAPALLDRIEAHVTAGRTLL
SVTLAAEDGEGLGWLYRHGEVLERESGADGHVVVSLRILPERVDLVKRRFGAAQVRGED

Sequences:

>Translated_459_residues
MELKGPRGAAGGGLKGVDRHAPPTRCAVITPQVTKRGARAGADRRSPEARLEEAVGLAAAIDLDVVYKGLVLISEVKPAT
YIGSGKVEEIAGIVAAEEVGLVFVDAALSPVQQRNLEKAWSAKVVDRTALILEIFGSRARTKEGTLQVELAHLNYQRSRL
VRSWTHLERQRGGFGFLGGPGETQIEADRRQIGERIIRIERELEQVKRTRALHRTSRKRVPYPVVALVGYTNAGKSTLFN
RLTQAEVMAQDLLFATLDPTLRAVDLPHGTRVILSDTVGFISELPTQLVAAFRATLEEVIEADVILHVRDISHPDTDAQA
ADVKDVLTELGIDVEAGGRLVEVWNKIDILPEAEREQLLNTAARAEPEARPELVSALTGEGAPALLDRIEAHVTAGRTLL
SVTLAAEDGEGLGWLYRHGEVLERESGADGHVVVSLRILPERVDLVKRRFGAAQVRGED
>Mature_459_residues
MELKGPRGAAGGGLKGVDRHAPPTRCAVITPQVTKRGARAGADRRSPEARLEEAVGLAAAIDLDVVYKGLVLISEVKPAT
YIGSGKVEEIAGIVAAEEVGLVFVDAALSPVQQRNLEKAWSAKVVDRTALILEIFGSRARTKEGTLQVELAHLNYQRSRL
VRSWTHLERQRGGFGFLGGPGETQIEADRRQIGERIIRIERELEQVKRTRALHRTSRKRVPYPVVALVGYTNAGKSTLFN
RLTQAEVMAQDLLFATLDPTLRAVDLPHGTRVILSDTVGFISELPTQLVAAFRATLEEVIEADVILHVRDISHPDTDAQA
ADVKDVLTELGIDVEAGGRLVEVWNKIDILPEAEREQLLNTAARAEPEARPELVSALTGEGAPALLDRIEAHVTAGRTLL
SVTLAAEDGEGLGWLYRHGEVLERESGADGHVVVSLRILPERVDLVKRRFGAAQVRGED

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=288, Percent_Identity=37.1527777777778, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI310133116, Length=286, Percent_Identity=37.0629370629371, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI310124269, Length=267, Percent_Identity=37.8277153558052, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI310124267, Length=267, Percent_Identity=37.8277153558052, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI310124171, Length=267, Percent_Identity=37.8277153558052, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI310124169, Length=267, Percent_Identity=37.8277153558052, Blast_Score=154, Evalue=2e-37,
Organism=Escherichia coli, GI1790615, Length=367, Percent_Identity=44.9591280653951, Blast_Score=268, Evalue=5e-73,
Organism=Caenorhabditis elegans, GI17561038, Length=424, Percent_Identity=31.8396226415094, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24650079, Length=466, Percent_Identity=33.4763948497854, Blast_Score=173, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49956; Mature: 49956

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKGPRGAAGGGLKGVDRHAPPTRCAVITPQVTKRGARAGADRRSPEARLEEAVGLAAA
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
IDLDVVYKGLVLISEVKPATYIGSGKVEEIAGIVAAEEVGLVFVDAALSPVQQRNLEKAW
HHHHHHHHHHHHEECCCCCEEECCCCHHHHHHHHHHHHCCEEEEECHHCHHHHHHHHHHH
SAKVVDRTALILEIFGSRARTKEGTLQVELAHLNYQRSRLVRSWTHLERQRGGFGFLGGP
HHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHCHHHHHHHHHHHHHHHHCCCCCCCCCC
GETQIEADRRQIGERIIRIERELEQVKRTRALHRTSRKRVPYPVVALVGYTNAGKSTLFN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHH
RLTQAEVMAQDLLFATLDPTLRAVDLPHGTRVILSDTVGFISELPTQLVAAFRATLEEVI
HHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
EADVILHVRDISHPDTDAQAADVKDVLTELGIDVEAGGRLVEVWNKIDILPEAEREQLLN
HHHHEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHEEHHHHHCCCCCHHHHHHHH
TAARAEPEARPELVSALTGEGAPALLDRIEAHVTAGRTLLSVTLAAEDGEGLGWLYRHGE
HHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHCCH
VLERESGADGHVVVSLRILPERVDLVKRRFGAAQVRGED
HHHHCCCCCCEEEEEEEECHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MELKGPRGAAGGGLKGVDRHAPPTRCAVITPQVTKRGARAGADRRSPEARLEEAVGLAAA
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
IDLDVVYKGLVLISEVKPATYIGSGKVEEIAGIVAAEEVGLVFVDAALSPVQQRNLEKAW
HHHHHHHHHHHHEECCCCCEEECCCCHHHHHHHHHHHHCCEEEEECHHCHHHHHHHHHHH
SAKVVDRTALILEIFGSRARTKEGTLQVELAHLNYQRSRLVRSWTHLERQRGGFGFLGGP
HHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHCHHHHHHHHHHHHHHHHCCCCCCCCCC
GETQIEADRRQIGERIIRIERELEQVKRTRALHRTSRKRVPYPVVALVGYTNAGKSTLFN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHH
RLTQAEVMAQDLLFATLDPTLRAVDLPHGTRVILSDTVGFISELPTQLVAAFRATLEEVI
HHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
EADVILHVRDISHPDTDAQAADVKDVLTELGIDVEAGGRLVEVWNKIDILPEAEREQLLN
HHHHEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHEEHHHHHCCCCCHHHHHHHH
TAARAEPEARPELVSALTGEGAPALLDRIEAHVTAGRTLLSVTLAAEDGEGLGWLYRHGE
HHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHCCH
VLERESGADGHVVVSLRILPERVDLVKRRFGAAQVRGED
HHHHCCCCCCEEEEEEEECHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]