Click here to switch to the map view.

The map label for this gene is dctB [H]

Identifier: 158424637

GI number: 158424637

Start: 3444858

End: 3446774

Strand: Reverse

Name: dctB [H]

Synonym: AZC_3013

Alternate gene names: 158424637

Gene position: 3446774-3444858 (Counterclockwise)

Preceding gene: 158424639

Following gene: 158424636

Centisome position: 64.19

GC content: 70.53

Gene sequence:

>1917_bases
TTGACGCTGTGTGCGGAAAGTCGCACATTGAAGCCGGCTGGCGCGTGCGGATTTTCGCACGGCGGCCGAGGAATTCCGGT
GACGACCCCTCTGCGTGATCGCCCGGGCGGTCAGGGATCCAAGGCTCGCCCGGTATCATGGCTCTTTCTGGGCGTGCTCG
CCCTGGCGGGCCTCATCGGCCTCGACGCGGCGGCGCGCCGGGGGGCCGAGCGCTGGGCGCTGTCCGAGGTGCGGGTCGCG
GCGGAAGCCGCCGTGGGCCTGCGGGTCGCCATGCTCCGCAGCGAGATCGAGAAGCAGCGCACGCTGCCGCAAGTGCTGGC
GGAGGACCCCGGTGTGCTTGCGGCGCTCGAGCGGCCCGACGAGGCGCGCATCCTCGCCCTCGATGCCCGGCTGGACGTGC
TGGCGGGGGCCACCCGCGCGGGGGCCATTTATCTGCTGGACCGCGAGGGCATGACCATCGCGGCCAGCAACTATCTCACG
CCTGAGAGCTTCGTCGGCAACGATTATTCCTTCCGCCCCTATTTCCGGCGCAGCATGGAGGTGGGGCAGGCGGAGCACTT
CGCCTTCGGCACTGTGAGCCACCGGCCGGGCCTGTATTTCTCCCGCCGGCTGGAGAAGGACGGCCAGCCCATCGGCGTCA
TCGTGGTGAAGGCCGAGTTCGACGCCGTGGAGGAGGAGTGGCGCCGCTTCGCCGAGCCGACCTATGCCGCCGACGAGCGC
GGCATCGTGCTGGTGGCGAGCGAGCCGGCGTGGCGCTTCCGGGCCACCGTTCCCATCCCTGAGGACCAGCGTGCGGAAAT
CCGCGCAAGCCTGCAATTCGGCGACGCGCCCCTCGATCTCCTGCCCATCCGCCCGGCGCCGGACCTGCCGGCGACGGTCC
TGACACTCGCGCCGCCCGCGCTCGCGGGACAGGATTTTGTCGAGGTGGATGCGCCCGTCCCCACCACCGGCTGGACACTG
CATCTTCTGGCGCCGACGGCCCCCTCGGTGGCGCTCGCCACCACGGCGGCCCGCTCGCTCGCCTTGCTGCTGGCGATCGC
CGGCATCGGCAGCGTCGGCTTCTGGGTGGCGCGGCGGCGGCGGCTGGAGGAGGAGCGCGAGCAGCAGGCGCTGGCCCGCC
GTGAGCTTGAGGCCCGCGTTGCGGAGCGCACCATGGAGCTTTCCGCCGCCAATGACCGGTTGCGGGGCGAGATCGAGGAG
CGCCGCCGCACGCAGGTGGCCCTCAACGAGATGCAGGACGAACTGGTGCAGGCGAGCAAGCTCGCGGTGCTCGGCCAGAT
CGCCGCCAGCGTCGCCCATGAGGTGAACCAGCCGGTGGCCGCCATCCGCACCTTCGCGGAGAATGCCCGGCAGTTCCTTG
ACCGGGGCGACGAGTCGACCGCCCGCGCCAACCTCGCCATCATCGGCGATCTCACCGAGCGGGTCGGCATCATCACCGGC
GAATTGCGCGATTTCGCCCGCAAGACACCGCCCGAGATCAGTCGCGTGCCGCTACGTGAGGTGATCGACGGTGCGCGCCT
GCTGGTGGGCCACCGGCTGCGTCAGGGCGACATCGTGCTGGACGTGGATCTCGGCCCCGAGGAGATTTCCGTGGCCGTCG
CTCCGGTGCGTCTGGAGCAGGTGTTTGTGAACCTTCTGCAGAACGCGGCCGAAGCCATCGGCGAGCGTGCCGGGGGGCGC
ATCCGCATCGAGGCCCGCGCCGACAATGGGCGTGTCACGGTCACGGTTTCCGACAACGGGCCGGGCCTGCCGCAGGAGGT
GCGCGAGGCTCTCTTCATGCCTTTCGTGACCACCAAGTCCACCGGCCTCGGCCTCGGGCTGGTGATCTCGCGGGACATCG
TCGCCGAATTCGGCGGCACCTTCGGCGCCGGCGAAGGGCCGGGCGCCGTCTTCACTTTGACCTTGCCGAGAGCCTGA

Upstream 100 bases:

>100_bases
GCCGACGATTTCGCAAGGTCCGTGCCAAGGGAGGGCTGGGTATCGCGCTCCGGCATGTCTTTGAATCTTAAGGAAGAGTT
TCCGCGCGTCTCACACCGGA

Downstream 100 bases:

>100_bases
TCCATGGACGTGGCCTTCATCGACGACGACGAGATCCTGCGGGCGGCCAATGTGCAGGCCCTCATGCTCGCCGGCCTCAC
CGTTGCGCCCTTCGGCTCGG

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 638; Mature: 637

Protein sequence:

>638_residues
MTLCAESRTLKPAGACGFSHGGRGIPVTTPLRDRPGGQGSKARPVSWLFLGVLALAGLIGLDAAARRGAERWALSEVRVA
AEAAVGLRVAMLRSEIEKQRTLPQVLAEDPGVLAALERPDEARILALDARLDVLAGATRAGAIYLLDREGMTIAASNYLT
PESFVGNDYSFRPYFRRSMEVGQAEHFAFGTVSHRPGLYFSRRLEKDGQPIGVIVVKAEFDAVEEEWRRFAEPTYAADER
GIVLVASEPAWRFRATVPIPEDQRAEIRASLQFGDAPLDLLPIRPAPDLPATVLTLAPPALAGQDFVEVDAPVPTTGWTL
HLLAPTAPSVALATTAARSLALLLAIAGIGSVGFWVARRRRLEEEREQQALARRELEARVAERTMELSAANDRLRGEIEE
RRRTQVALNEMQDELVQASKLAVLGQIAASVAHEVNQPVAAIRTFAENARQFLDRGDESTARANLAIIGDLTERVGIITG
ELRDFARKTPPEISRVPLREVIDGARLLVGHRLRQGDIVLDVDLGPEEISVAVAPVRLEQVFVNLLQNAAEAIGERAGGR
IRIEARADNGRVTVTVSDNGPGLPQEVREALFMPFVTTKSTGLGLGLVISRDIVAEFGGTFGAGEGPGAVFTLTLPRA

Sequences:

>Translated_638_residues
MTLCAESRTLKPAGACGFSHGGRGIPVTTPLRDRPGGQGSKARPVSWLFLGVLALAGLIGLDAAARRGAERWALSEVRVA
AEAAVGLRVAMLRSEIEKQRTLPQVLAEDPGVLAALERPDEARILALDARLDVLAGATRAGAIYLLDREGMTIAASNYLT
PESFVGNDYSFRPYFRRSMEVGQAEHFAFGTVSHRPGLYFSRRLEKDGQPIGVIVVKAEFDAVEEEWRRFAEPTYAADER
GIVLVASEPAWRFRATVPIPEDQRAEIRASLQFGDAPLDLLPIRPAPDLPATVLTLAPPALAGQDFVEVDAPVPTTGWTL
HLLAPTAPSVALATTAARSLALLLAIAGIGSVGFWVARRRRLEEEREQQALARRELEARVAERTMELSAANDRLRGEIEE
RRRTQVALNEMQDELVQASKLAVLGQIAASVAHEVNQPVAAIRTFAENARQFLDRGDESTARANLAIIGDLTERVGIITG
ELRDFARKTPPEISRVPLREVIDGARLLVGHRLRQGDIVLDVDLGPEEISVAVAPVRLEQVFVNLLQNAAEAIGERAGGR
IRIEARADNGRVTVTVSDNGPGLPQEVREALFMPFVTTKSTGLGLGLVISRDIVAEFGGTFGAGEGPGAVFTLTLPRA
>Mature_637_residues
TLCAESRTLKPAGACGFSHGGRGIPVTTPLRDRPGGQGSKARPVSWLFLGVLALAGLIGLDAAARRGAERWALSEVRVAA
EAAVGLRVAMLRSEIEKQRTLPQVLAEDPGVLAALERPDEARILALDARLDVLAGATRAGAIYLLDREGMTIAASNYLTP
ESFVGNDYSFRPYFRRSMEVGQAEHFAFGTVSHRPGLYFSRRLEKDGQPIGVIVVKAEFDAVEEEWRRFAEPTYAADERG
IVLVASEPAWRFRATVPIPEDQRAEIRASLQFGDAPLDLLPIRPAPDLPATVLTLAPPALAGQDFVEVDAPVPTTGWTLH
LLAPTAPSVALATTAARSLALLLAIAGIGSVGFWVARRRRLEEEREQQALARRELEARVAERTMELSAANDRLRGEIEER
RRTQVALNEMQDELVQASKLAVLGQIAASVAHEVNQPVAAIRTFAENARQFLDRGDESTARANLAIIGDLTERVGIITGE
LRDFARKTPPEISRVPLREVIDGARLLVGHRLRQGDIVLDVDLGPEEISVAVAPVRLEQVFVNLLQNAAEAIGERAGGRI
RIEARADNGRVTVTVSDNGPGLPQEVREALFMPFVTTKSTGLGLGLVISRDIVAEFGGTFGAGEGPGAVFTLTLPRA

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=229, Percent_Identity=32.7510917030568, Blast_Score=116, Evalue=5e-27,
Organism=Escherichia coli, GI1788549, Length=264, Percent_Identity=30.3030303030303, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1790300, Length=131, Percent_Identity=32.0610687022901, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789149, Length=295, Percent_Identity=25.0847457627119, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786912, Length=106, Percent_Identity=39.622641509434, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 68862; Mature: 68730

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLCAESRTLKPAGACGFSHGGRGIPVTTPLRDRPGGQGSKARPVSWLFLGVLALAGLIG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LDAAARRGAERWALSEVRVAAEAAVGLRVAMLRSEIEKQRTLPQVLAEDPGVLAALERPD
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
EARILALDARLDVLAGATRAGAIYLLDREGMTIAASNYLTPESFVGNDYSFRPYFRRSME
CCEEEEEECCHHHHHCCCCCCEEEEEECCCCEEEECCCCCCHHHCCCCCCCCHHHHHHHH
VGQAEHFAFGTVSHRPGLYFSRRLEKDGQPIGVIVVKAEFDAVEEEWRRFAEPTYAADER
CCCCHHEEEECCCCCCCCHHHHHHCCCCCCEEEEEEEECHHHHHHHHHHHCCCCCCCCCC
GIVLVASEPAWRFRATVPIPEDQRAEIRASLQFGDAPLDLLPIRPAPDLPATVLTLAPPA
CEEEEECCCCCEEEEECCCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCEEEEEECCCC
LAGQDFVEVDAPVPTTGWTLHLLAPTAPSVALATTAARSLALLLAIAGIGSVGFWVARRR
CCCCCCEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RLEEEREQQALARRELEARVAERTMELSAANDRLRGEIEERRRTQVALNEMQDELVQASK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVLGQIAASVAHEVNQPVAAIRTFAENARQFLDRGDESTARANLAIIGDLTERVGIITG
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHEEEEEEECHHHHHHHEEH
ELRDFARKTPPEISRVPLREVIDGARLLVGHRLRQGDIVLDVDLGPEEISVAVAPVRLEQ
HHHHHHHCCCCCHHCCCHHHHHCHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEHHHHHH
VFVNLLQNAAEAIGERAGGRIRIEARADNGRVTVTVSDNGPGLPQEVREALFMPFVTTKS
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHCCCEEECC
TGLGLGLVISRDIVAEFGGTFGAGEGPGAVFTLTLPRA
CCCCEEEEHHHHHHHHCCCCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure 
TLCAESRTLKPAGACGFSHGGRGIPVTTPLRDRPGGQGSKARPVSWLFLGVLALAGLIG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LDAAARRGAERWALSEVRVAAEAAVGLRVAMLRSEIEKQRTLPQVLAEDPGVLAALERPD
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
EARILALDARLDVLAGATRAGAIYLLDREGMTIAASNYLTPESFVGNDYSFRPYFRRSME
CCEEEEEECCHHHHHCCCCCCEEEEEECCCCEEEECCCCCCHHHCCCCCCCCHHHHHHHH
VGQAEHFAFGTVSHRPGLYFSRRLEKDGQPIGVIVVKAEFDAVEEEWRRFAEPTYAADER
CCCCHHEEEECCCCCCCCHHHHHHCCCCCCEEEEEEEECHHHHHHHHHHHCCCCCCCCCC
GIVLVASEPAWRFRATVPIPEDQRAEIRASLQFGDAPLDLLPIRPAPDLPATVLTLAPPA
CEEEEECCCCCEEEEECCCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCEEEEEECCCC
LAGQDFVEVDAPVPTTGWTLHLLAPTAPSVALATTAARSLALLLAIAGIGSVGFWVARRR
CCCCCCEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RLEEEREQQALARRELEARVAERTMELSAANDRLRGEIEERRRTQVALNEMQDELVQASK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVLGQIAASVAHEVNQPVAAIRTFAENARQFLDRGDESTARANLAIIGDLTERVGIITG
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHEEEEEEECHHHHHHHEEH
ELRDFARKTPPEISRVPLREVIDGARLLVGHRLRQGDIVLDVDLGPEEISVAVAPVRLEQ
HHHHHHHCCCCCHHCCCHHHHHCHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEHHHHHH
VFVNLLQNAAEAIGERAGGRIRIEARADNGRVTVTVSDNGPGLPQEVREALFMPFVTTKS
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHCCCEEECC
TGLGLGLVISRDIVAEFGGTFGAGEGPGAVFTLTLPRA
CCCCEEEEHHHHHHHHCCCCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]