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The map label for this gene is dctD [H]

Identifier: 158424636

GI number: 158424636

Start: 3443514

End: 3444854

Strand: Reverse

Name: dctD [H]

Synonym: AZC_3012

Alternate gene names: 158424636

Gene position: 3444854-3443514 (Counterclockwise)

Preceding gene: 158424637

Following gene: 158424633

Centisome position: 64.15

GC content: 68.31

Gene sequence:

>1341_bases
ATGGACGTGGCCTTCATCGACGACGACGAGATCCTGCGGGCGGCCAATGTGCAGGCCCTCATGCTCGCCGGCCTCACCGT
TGCGCCCTTCGGCTCGGCGCAGGCCGCGCTCGATGCCATCGACCCGACCTTTCCCGGCGTGGTGGTGAGCGACGTGCGCA
TGCCGCGCATCGACGGGCTCGAGCTGTTCCGCCGTCTGAGAAAGGTCGATCCGGAACTCCCGGTCATCCTCATCACCGGC
CATGGCGACATCGCCATGGCGGTGGAGGCGATGCGCGAGGGCGCCTATGACTTCCTCGCCAAGCCCTATGCGGGTGATCG
CCTGCTCGGCAGCATCCGCCACGCGCTGGAGAAGCGCCGGCTGGTGCTGGAAAATCGCGAACTGAAGCGCGCCGCGGAGG
CGGCGGGAGAGGAATTTCCCCTGCTCGGTGCCGATCCGGCCATGGAACGCCTGCGCCAGACCCTGCGCCAGCTTGCCGAT
GCGGATGTGGACGTGCTGGTGGAAGGGGAGACCGGCAGCGGCAAGGAAGTGGTGGCGAACCTGCTCCATCGGTTGAGCCA
TCGCTCCACCCGGCCCTTCGTGGCCGTCAATTGCGGGGCGCTGCCGGAGACGATGATCGAGAGCGAGCTGTTCGGCCATG
AGGCGGGCGCCTTCACCGGGGCGCTCAAGAAGAGGGTGGGGCGCATCGCCTTCGCCAATGGCGGCACACTCTTCCTCGAC
GAGATCGAGGCCATGTCACCGGCCTTGCAGGTGAAGCTGCTGCGGGTGCTGGAAGCCCGCGAGGTGATCCCGCTCGGCGC
CAATGAAGCGCGCAAGGTGGACATCCGCGTCGTCACCGCCTCGAAGATCGACCTGCGCGAACTGGTGCGGGCCGACAAGT
TCCGCGAGGATCTCTATTACCGGCTGCACGTGGCGGCCGTGCGCATCCCGCCCTTGCGCGAGCGGCGCTCGGACATTGCG
CTGCTGTTCGGCCACTTCCTCGCCCATGCGGCCAAGCGTTTCCGCCGCGAGCCGCCGCTGGTGGGGCGGCCAGTGCTCGA
CCGCCTGGAAGCGCACGACTGGCCGGGCAATGTGCGCGAGCTGATGCATTATGCCGAGCGTGTGGCCCTCGGCCTCGTCG
ATCCGCCCGCCGCCACCGCTGTCCTGCCCGATACGAGCCTGACACTGCCGCAGCGGGTGGAAGCCTTCGAGGCGGAGCAG
ATCCGCGCGGCGCTGGCTACGGCACAGGGCGATGTTCAGGCGACCGTGAAGGCCCTCGGCATCCCTCGCAAGACCTTCTA
CGACAAGCTGCATCGCCACGGCATCGACCAGAATGCGTTCCGCCCCGCCGGCCGGGCCTGA

Upstream 100 bases:

>100_bases
GGTGATCTCGCGGGACATCGTCGCCGAATTCGGCGGCACCTTCGGCGCCGGCGAAGGGCCGGGCGCCGTCTTCACTTTGA
CCTTGCCGAGAGCCTGATCC

Downstream 100 bases:

>100_bases
ACCAGCTCAGGCGATGAAGGCCTCATAGTCCGCCGGCTTGAACCCGACGAGGATGCCGCCGTCCTTCTCCAGCACCGGGC
GCTTGATCATGGAGGGCTGC

Product: two component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MDVAFIDDDEILRAANVQALMLAGLTVAPFGSAQAALDAIDPTFPGVVVSDVRMPRIDGLELFRRLRKVDPELPVILITG
HGDIAMAVEAMREGAYDFLAKPYAGDRLLGSIRHALEKRRLVLENRELKRAAEAAGEEFPLLGADPAMERLRQTLRQLAD
ADVDVLVEGETGSGKEVVANLLHRLSHRSTRPFVAVNCGALPETMIESELFGHEAGAFTGALKKRVGRIAFANGGTLFLD
EIEAMSPALQVKLLRVLEAREVIPLGANEARKVDIRVVTASKIDLRELVRADKFREDLYYRLHVAAVRIPPLRERRSDIA
LLFGHFLAHAAKRFRREPPLVGRPVLDRLEAHDWPGNVRELMHYAERVALGLVDPPAATAVLPDTSLTLPQRVEAFEAEQ
IRAALATAQGDVQATVKALGIPRKTFYDKLHRHGIDQNAFRPAGRA

Sequences:

>Translated_446_residues
MDVAFIDDDEILRAANVQALMLAGLTVAPFGSAQAALDAIDPTFPGVVVSDVRMPRIDGLELFRRLRKVDPELPVILITG
HGDIAMAVEAMREGAYDFLAKPYAGDRLLGSIRHALEKRRLVLENRELKRAAEAAGEEFPLLGADPAMERLRQTLRQLAD
ADVDVLVEGETGSGKEVVANLLHRLSHRSTRPFVAVNCGALPETMIESELFGHEAGAFTGALKKRVGRIAFANGGTLFLD
EIEAMSPALQVKLLRVLEAREVIPLGANEARKVDIRVVTASKIDLRELVRADKFREDLYYRLHVAAVRIPPLRERRSDIA
LLFGHFLAHAAKRFRREPPLVGRPVLDRLEAHDWPGNVRELMHYAERVALGLVDPPAATAVLPDTSLTLPQRVEAFEAEQ
IRAALATAQGDVQATVKALGIPRKTFYDKLHRHGIDQNAFRPAGRA
>Mature_446_residues
MDVAFIDDDEILRAANVQALMLAGLTVAPFGSAQAALDAIDPTFPGVVVSDVRMPRIDGLELFRRLRKVDPELPVILITG
HGDIAMAVEAMREGAYDFLAKPYAGDRLLGSIRHALEKRRLVLENRELKRAAEAAGEEFPLLGADPAMERLRQTLRQLAD
ADVDVLVEGETGSGKEVVANLLHRLSHRSTRPFVAVNCGALPETMIESELFGHEAGAFTGALKKRVGRIAFANGGTLFLD
EIEAMSPALQVKLLRVLEAREVIPLGANEARKVDIRVVTASKIDLRELVRADKFREDLYYRLHVAAVRIPPLRERRSDIA
LLFGHFLAHAAKRFRREPPLVGRPVLDRLEAHDWPGNVRELMHYAERVALGLVDPPAATAVLPDTSLTLPQRVEAFEAEQ
IRAALATAQGDVQATVKALGIPRKTFYDKLHRHGIDQNAFRPAGRA

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788905, Length=447, Percent_Identity=39.8210290827741, Blast_Score=302, Evalue=3e-83,
Organism=Escherichia coli, GI1790437, Length=442, Percent_Identity=39.5927601809955, Blast_Score=300, Evalue=2e-82,
Organism=Escherichia coli, GI1788550, Length=451, Percent_Identity=36.5853658536585, Blast_Score=288, Evalue=7e-79,
Organism=Escherichia coli, GI1790299, Length=359, Percent_Identity=41.7827298050139, Blast_Score=272, Evalue=4e-74,
Organism=Escherichia coli, GI1789087, Length=336, Percent_Identity=39.8809523809524, Blast_Score=214, Evalue=8e-57,
Organism=Escherichia coli, GI1789233, Length=261, Percent_Identity=44.0613026819923, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI87082152, Length=313, Percent_Identity=38.9776357827476, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI87082117, Length=224, Percent_Identity=47.7678571428571, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1786524, Length=309, Percent_Identity=40.453074433657, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI87081872, Length=319, Percent_Identity=37.6175548589342, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1787583, Length=337, Percent_Identity=32.3442136498516, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI87081858, Length=310, Percent_Identity=33.5483870967742, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789828, Length=241, Percent_Identity=33.6099585062241, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 49139; Mature: 49139

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVAFIDDDEILRAANVQALMLAGLTVAPFGSAQAALDAIDPTFPGVVVSDVRMPRIDGL
CCEEECCCHHHHHHCCHHHHHHCCCEECCCCCHHHHHHHCCCCCCCEEEECCCCCCCCHH
ELFRRLRKVDPELPVILITGHGDIAMAVEAMREGAYDFLAKPYAGDRLLGSIRHALEKRR
HHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHH
LVLENRELKRAAEAAGEEFPLLGADPAMERLRQTLRQLADADVDVLVEGETGSGKEVVAN
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHH
LLHRLSHRSTRPFVAVNCGALPETMIESELFGHEAGAFTGALKKRVGRIAFANGGTLFLD
HHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHCEEEEECCCEEEEH
EIEAMSPALQVKLLRVLEAREVIPLGANEARKVDIRVVTASKIDLRELVRADKFREDLYY
HHHHHCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHH
RLHVAAVRIPPLRERRSDIALLFGHFLAHAAKRFRREPPLVGRPVLDRLEAHDWPGNVRE
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCHHHH
LMHYAERVALGLVDPPAATAVLPDTSLTLPQRVEAFEAEQIRAALATAQGDVQATVKALG
HHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
IPRKTFYDKLHRHGIDQNAFRPAGRA
CCHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MDVAFIDDDEILRAANVQALMLAGLTVAPFGSAQAALDAIDPTFPGVVVSDVRMPRIDGL
CCEEECCCHHHHHHCCHHHHHHCCCEECCCCCHHHHHHHCCCCCCCEEEECCCCCCCCHH
ELFRRLRKVDPELPVILITGHGDIAMAVEAMREGAYDFLAKPYAGDRLLGSIRHALEKRR
HHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHH
LVLENRELKRAAEAAGEEFPLLGADPAMERLRQTLRQLADADVDVLVEGETGSGKEVVAN
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHH
LLHRLSHRSTRPFVAVNCGALPETMIESELFGHEAGAFTGALKKRVGRIAFANGGTLFLD
HHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHCEEEEECCCEEEEH
EIEAMSPALQVKLLRVLEAREVIPLGANEARKVDIRVVTASKIDLRELVRADKFREDLYY
HHHHHCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHH
RLHVAAVRIPPLRERRSDIALLFGHFLAHAAKRFRREPPLVGRPVLDRLEAHDWPGNVRE
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCHHHH
LMHYAERVALGLVDPPAATAVLPDTSLTLPQRVEAFEAEQIRAALATAQGDVQATVKALG
HHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
IPRKTFYDKLHRHGIDQNAFRPAGRA
CCHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431 [H]