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The map label for this gene is tas [H]

Identifier: 158424613

GI number: 158424613

Start: 3417824

End: 3418879

Strand: Direct

Name: tas [H]

Synonym: AZC_2989

Alternate gene names: 158424613

Gene position: 3417824-3418879 (Clockwise)

Preceding gene: 158424612

Following gene: 158424622

Centisome position: 63.65

GC content: 65.15

Gene sequence:

>1056_bases
ATGCTTGAGTATCGCAGGCTCGGACGCACCGACCTCAAGGTGTCGTCCATCATGCTCGGCACCATGACCTGGGGCCAGCA
GAACACGGAAGCCGAAGGCCACGCCCAGCTCGACCTCGCGCTCGATGCCGGCATCAACTTCATCGACACCGCCGAACTCT
ATTCCATCCCGCCCATGGCGGAGACGCAGGGCTCCACCGAGCGGATCATTGGTCAGTGGTTCAAGAGCCGCAAAAATCGC
GACAAGGTGATTCTCGCCTCGAAGGTGGTGGGCCGCTCCGACAGCACCTATTTCCGCGCCTCCGGCGAAGGCACGAAGCT
CGACCGGGCGAATATCACCGAGGCGGTCGAGAACTCCCTGAAGCGCCTCCAGACGGACTATATCGACCTCTACCAGCTCC
ACTGGCCGGACCGCGCCGTGCCGCTCTTCGGCAATTCGGCCGGCACCCGCGCGCGGGGCGGCGGGGACGGCACGGAAGTG
CCGGTCGCCGAGACGCTGGGCGTGCTGGAGGATCTGGTGAAGGCCGGCAAGATCCGCCACATCGGCCTCTCCAACGAGAC
CGCATGGGGCGCGCATAAATTCCTGCTGGAAGCCGAGCGCGGGCATGGTCCGCGTATCGTCTCGGTCCAGAACGCCTACA
ACCTCATCAACCGCACCTATGAGGTGGGGCTGGCGGAATTTGCCGAGCGGGATGATGTGGGCCTGCTCGCTTACTCCCCC
CTCGCGCAGGGTTTCCTCACTGGCAAGTATCGCCAGGGCGCCCGGCCCGAGGGCGCGCGCATGACGCTGTTCAATCGCGG
CCAGCGCTACGAAAAGCCCGGCACGGCGGAAGCCATCGAGGATTATGCGGCGCTGGCGAAGGAACTCGGCCTGTCGCTCG
TTCAGCTCTCGCTCGCCTGGGTGACGTCGCGGCCCTTCGTGACCGCCAACATCATCGGCGCGACCAGCATCGCCCAGTTG
AAGGAAAACCTCGCCACCGTGGATGTCGCCATCACGCAGGAGATCGAAGAGAAGGTGAACGCCATCTTCCAGCTGCGCGG
CAGCCCGGCGCCCTGA

Upstream 100 bases:

>100_bases
CAACTGCCGTTGCGTCCGCTTGCCAAGGGCCAAGGCGAAGCTGCTACAAAGCGCTATCCGCCGGCCGCGCCGGCGCCCCG
CCCACGGAGTTTTCCGCCAC

Downstream 100 bases:

>100_bases
TCCACGAACGGCGCGCGGGCTGCCCGCGCGCCGGACCTCTCAGAAAATCGCGGTGTGCATGGAGCCGTCGGCCTGCATCC
AGGCGCGGTACATGCCCTCG

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MLEYRRLGRTDLKVSSIMLGTMTWGQQNTEAEGHAQLDLALDAGINFIDTAELYSIPPMAETQGSTERIIGQWFKSRKNR
DKVILASKVVGRSDSTYFRASGEGTKLDRANITEAVENSLKRLQTDYIDLYQLHWPDRAVPLFGNSAGTRARGGGDGTEV
PVAETLGVLEDLVKAGKIRHIGLSNETAWGAHKFLLEAERGHGPRIVSVQNAYNLINRTYEVGLAEFAERDDVGLLAYSP
LAQGFLTGKYRQGARPEGARMTLFNRGQRYEKPGTAEAIEDYAALAKELGLSLVQLSLAWVTSRPFVTANIIGATSIAQL
KENLATVDVAITQEIEEKVNAIFQLRGSPAP

Sequences:

>Translated_351_residues
MLEYRRLGRTDLKVSSIMLGTMTWGQQNTEAEGHAQLDLALDAGINFIDTAELYSIPPMAETQGSTERIIGQWFKSRKNR
DKVILASKVVGRSDSTYFRASGEGTKLDRANITEAVENSLKRLQTDYIDLYQLHWPDRAVPLFGNSAGTRARGGGDGTEV
PVAETLGVLEDLVKAGKIRHIGLSNETAWGAHKFLLEAERGHGPRIVSVQNAYNLINRTYEVGLAEFAERDDVGLLAYSP
LAQGFLTGKYRQGARPEGARMTLFNRGQRYEKPGTAEAIEDYAALAKELGLSLVQLSLAWVTSRPFVTANIIGATSIAQL
KENLATVDVAITQEIEEKVNAIFQLRGSPAP
>Mature_351_residues
MLEYRRLGRTDLKVSSIMLGTMTWGQQNTEAEGHAQLDLALDAGINFIDTAELYSIPPMAETQGSTERIIGQWFKSRKNR
DKVILASKVVGRSDSTYFRASGEGTKLDRANITEAVENSLKRLQTDYIDLYQLHWPDRAVPLFGNSAGTRARGGGDGTEV
PVAETLGVLEDLVKAGKIRHIGLSNETAWGAHKFLLEAERGHGPRIVSVQNAYNLINRTYEVGLAEFAERDDVGLLAYSP
LAQGFLTGKYRQGARPEGARMTLFNRGQRYEKPGTAEAIEDYAALAKELGLSLVQLSLAWVTSRPFVTANIIGATSIAQL
KENLATVDVAITQEIEEKVNAIFQLRGSPAP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=360, Percent_Identity=27.2222222222222, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI27436962, Length=360, Percent_Identity=27.2222222222222, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI27436966, Length=360, Percent_Identity=26.9444444444444, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI4504825, Length=351, Percent_Identity=26.7806267806268, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI27436969, Length=351, Percent_Identity=26.7806267806268, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI27436971, Length=359, Percent_Identity=26.1838440111421, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI41327764, Length=339, Percent_Identity=27.7286135693215, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI41152114, Length=330, Percent_Identity=26.0606060606061, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI223718702, Length=329, Percent_Identity=25.531914893617, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1789199, Length=354, Percent_Identity=45.4802259887006, Blast_Score=316, Evalue=2e-87,
Organism=Escherichia coli, GI87081735, Length=348, Percent_Identity=33.3333333333333, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1788070, Length=337, Percent_Identity=29.9703264094956, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789375, Length=337, Percent_Identity=27.5964391691395, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788081, Length=325, Percent_Identity=28.3076923076923, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17564128, Length=326, Percent_Identity=25.1533742331288, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=354, Percent_Identity=28.8135593220339, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6319958, Length=326, Percent_Identity=26.6871165644172, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6323998, Length=356, Percent_Identity=26.9662921348315, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319951, Length=338, Percent_Identity=24.5562130177515, Blast_Score=83, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6322615, Length=272, Percent_Identity=24.2647058823529, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321052, Length=137, Percent_Identity=32.8467153284672, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24646159, Length=261, Percent_Identity=31.8007662835249, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24646155, Length=341, Percent_Identity=27.5659824046921, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38495; Mature: 38495

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEYRRLGRTDLKVSSIMLGTMTWGQQNTEAEGHAQLDLALDAGINFIDTAELYSIPPMA
CCCCHHCCCCCCEEHHEEEEEEECCCCCCCCCCCEEEEEEECCCCCEEECHHHHCCCCCC
ETQGSTERIIGQWFKSRKNRDKVILASKVVGRSDSTYFRASGEGTKLDRANITEAVENSL
CCCCCHHHHHHHHHHCCCCCCEEEEEEHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHH
KRLQTDYIDLYQLHWPDRAVPLFGNSAGTRARGGGDGTEVPVAETLGVLEDLVKAGKIRH
HHHHHHHHHEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEE
IGLSNETAWGAHKFLLEAERGHGPRIVSVQNAYNLINRTYEVGLAEFAERDDVGLLAYSP
ECCCCCCCCCHHHHEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECH
LAQGFLTGKYRQGARPEGARMTLFNRGQRYEKPGTAEAIEDYAALAKELGLSLVQLSLAW
HHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHH
VTSRPFVTANIIGATSIAQLKENLATVDVAITQEIEEKVNAIFQLRGSPAP
HCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
>Mature Secondary Structure
MLEYRRLGRTDLKVSSIMLGTMTWGQQNTEAEGHAQLDLALDAGINFIDTAELYSIPPMA
CCCCHHCCCCCCEEHHEEEEEEECCCCCCCCCCCEEEEEEECCCCCEEECHHHHCCCCCC
ETQGSTERIIGQWFKSRKNRDKVILASKVVGRSDSTYFRASGEGTKLDRANITEAVENSL
CCCCCHHHHHHHHHHCCCCCCEEEEEEHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHH
KRLQTDYIDLYQLHWPDRAVPLFGNSAGTRARGGGDGTEVPVAETLGVLEDLVKAGKIRH
HHHHHHHHHEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEE
IGLSNETAWGAHKFLLEAERGHGPRIVSVQNAYNLINRTYEVGLAEFAERDDVGLLAYSP
ECCCCCCCCCHHHHEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECH
LAQGFLTGKYRQGARPEGARMTLFNRGQRYEKPGTAEAIEDYAALAKELGLSLVQLSLAW
HHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHH
VTSRPFVTANIIGATSIAQLKENLATVDVAITQEIEEKVNAIFQLRGSPAP
HCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]