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The map label for this gene is lysR [H]

Identifier: 158424590

GI number: 158424590

Start: 3387851

End: 3388732

Strand: Direct

Name: lysR [H]

Synonym: AZC_2966

Alternate gene names: 158424590

Gene position: 3387851-3388732 (Clockwise)

Preceding gene: 158424588

Following gene: 158424595

Centisome position: 63.09

GC content: 67.91

Gene sequence:

>882_bases
ATGACCGTTCTGCTCGATGCCGACCATTTGCGGACCTTCGCCGCCATTGCGGAGACCGGCAGCTTCACCAAGGCGGCCGA
GGTCGTACACAAGACCCAGTCCGCTGTTTCCATGCAGATGAAGCGGCTGGAGGACCGGGTGGGACGGCCGCTGTTTGCCC
GTGACGGCCGCGCCTCGCGGCTGACGCCGGACGGCGAAAAGCTGCTCGACTATGCCCGGCGCATCGTGAAGCTCAATCTG
GAGGCGGTCTCGGCCTTCACCGACCAGACGCTCTCCGGCCGCGTGTGCCTCGGCGTGCCGGACGATTACGCCGACCGCTA
TCTCCCCGACATCATGGCCCGGTTTTCCCGCACCCATCCCTCCGTCGAGCTGACGGTGGTGTGCGAGCCAAGTCAAAGGC
TGAACGAGAGCATCGCGGCCGGGGCCATCGACCTTGCCATCATCACCGCCACCGACATCTCCAACCGCAATGTGCAGGTG
ATCCGGCGCGAGCGCCTGCTGTGGGTGGGATCGCTCCGCCATTCCGCACATCTGGAGGAGCCGACGCCGCTCGCCCTCGG
CCAGCCCACCTGCCAGTGGCGGGACGTGGCGGTGGCGGGCCTGCATAAGTCAAAGCGCGGCTATCGCATTCTCTACAGCA
GCCCCAACCATGGGGCGGTTTCCGCCGCGGTGCTGGCAGGCCTTGCCATCTCGGTCGTGCCCGAATCGGCCCTGCGCCCC
GGCATGCGGGTGCTGGGGGCGGCCGAAGGCTTCCCGCCGCTTCCGCCCTGCGACATCGGCCTGCTGCGCAACCCGCATGA
GCCCTCGGCGCTCGCGGAGGCGCTGGCCCACCACATCATTCAGGGGCTGGACAATCTCACCGAGGCCGACGCGGCGGAAT
AG

Upstream 100 bases:

>100_bases
CGCGGTTGGCTCCTCTTGTGTCCGAGAGCGATGAATCAGACTAGCGAATGTTATTCATCGCTCATATCATCGTGTGTGAT
GACTTCGGGACGCTGGCGCC

Downstream 100 bases:

>100_bases
CCGCGCCGATCCTTCGGAACGCGATCCAAAAACCGGATCAGTAGGCGAGTTCTTCGAACACCGGCTCCACCGAGCCCTGC
CAGGCGCCGTGATAGCGGGA

Product: transcriptional regulator

Products: NA

Alternate protein names: 2,2-dialkylglycine decarboxylase repressor [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MTVLLDADHLRTFAAIAETGSFTKAAEVVHKTQSAVSMQMKRLEDRVGRPLFARDGRASRLTPDGEKLLDYARRIVKLNL
EAVSAFTDQTLSGRVCLGVPDDYADRYLPDIMARFSRTHPSVELTVVCEPSQRLNESIAAGAIDLAIITATDISNRNVQV
IRRERLLWVGSLRHSAHLEEPTPLALGQPTCQWRDVAVAGLHKSKRGYRILYSSPNHGAVSAAVLAGLAISVVPESALRP
GMRVLGAAEGFPPLPPCDIGLLRNPHEPSALAEALAHHIIQGLDNLTEADAAE

Sequences:

>Translated_293_residues
MTVLLDADHLRTFAAIAETGSFTKAAEVVHKTQSAVSMQMKRLEDRVGRPLFARDGRASRLTPDGEKLLDYARRIVKLNL
EAVSAFTDQTLSGRVCLGVPDDYADRYLPDIMARFSRTHPSVELTVVCEPSQRLNESIAAGAIDLAIITATDISNRNVQV
IRRERLLWVGSLRHSAHLEEPTPLALGQPTCQWRDVAVAGLHKSKRGYRILYSSPNHGAVSAAVLAGLAISVVPESALRP
GMRVLGAAEGFPPLPPCDIGLLRNPHEPSALAEALAHHIIQGLDNLTEADAAE
>Mature_292_residues
TVLLDADHLRTFAAIAETGSFTKAAEVVHKTQSAVSMQMKRLEDRVGRPLFARDGRASRLTPDGEKLLDYARRIVKLNLE
AVSAFTDQTLSGRVCLGVPDDYADRYLPDIMARFSRTHPSVELTVVCEPSQRLNESIAAGAIDLAIITATDISNRNVQVI
RRERLLWVGSLRHSAHLEEPTPLALGQPTCQWRDVAVAGLHKSKRGYRILYSSPNHGAVSAAVLAGLAISVVPESALRPG
MRVLGAAEGFPPLPPCDIGLLRNPHEPSALAEALAHHIIQGLDNLTEADAAE

Specific function: Not Known, Does Not Seem To Act On The Proton Translocating NADH Dehydrogenase Genes (Nuoa-N) Which Are Part Of The Lrha Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=271, Percent_Identity=36.1623616236162, Blast_Score=161, Evalue=5e-41,
Organism=Escherichia coli, GI1787806, Length=244, Percent_Identity=25.8196721311475, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790208, Length=145, Percent_Identity=33.7931034482759, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI157672245, Length=145, Percent_Identity=32.4137931034483, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790262, Length=154, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786713, Length=70, Percent_Identity=50, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI145693105, Length=151, Percent_Identity=25.1655629139073, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1788748, Length=145, Percent_Identity=31.7241379310345, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788887, Length=145, Percent_Identity=29.6551724137931, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI87081904, Length=166, Percent_Identity=27.710843373494, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1790399, Length=285, Percent_Identity=24.9122807017544, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789173, Length=139, Percent_Identity=30.9352517985612, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31767; Mature: 31636

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLLDADHLRTFAAIAETGSFTKAAEVVHKTQSAVSMQMKRLEDRVGRPLFARDGRASR
CEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
LTPDGEKLLDYARRIVKLNLEAVSAFTDQTLSGRVCLGVPDDYADRYLPDIMARFSRTHP
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCC
SVELTVVCEPSQRLNESIAAGAIDLAIITATDISNRNVQVIRRERLLWVGSLRHSAHLEE
CEEEEEEECCHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCC
PTPLALGQPTCQWRDVAVAGLHKSKRGYRILYSSPNHGAVSAAVLAGLAISVVPESALRP
CCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHCC
GMRVLGAAEGFPPLPPCDIGLLRNPHEPSALAEALAHHIIQGLDNLTEADAAE
CHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TVLLDADHLRTFAAIAETGSFTKAAEVVHKTQSAVSMQMKRLEDRVGRPLFARDGRASR
EEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
LTPDGEKLLDYARRIVKLNLEAVSAFTDQTLSGRVCLGVPDDYADRYLPDIMARFSRTHP
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCC
SVELTVVCEPSQRLNESIAAGAIDLAIITATDISNRNVQVIRRERLLWVGSLRHSAHLEE
CEEEEEEECCHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCC
PTPLALGQPTCQWRDVAVAGLHKSKRGYRILYSSPNHGAVSAAVLAGLAISVVPESALRP
CCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHCC
GMRVLGAAEGFPPLPPCDIGLLRNPHEPSALAEALAHHIIQGLDNLTEADAAE
CHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180928 [H]