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The map label for this gene is iclR [H]

Identifier: 158424489

GI number: 158424489

Start: 3263585

End: 3264397

Strand: Reverse

Name: iclR [H]

Synonym: AZC_2865

Alternate gene names: 158424489

Gene position: 3264397-3263585 (Counterclockwise)

Preceding gene: 158424490

Following gene: 158424488

Centisome position: 60.79

GC content: 66.3

Gene sequence:

>813_bases
ATGATGACCCAGCCCGAAGCCCAGACGAGCGACCTCGACGAAGGCGATGCCAAGGAAGACCGGCACTTCGTCACCGCCCT
CGCGCGCGGGCTGGAGGTTCTGGCGTGCTTCAAGCGGGGCGAGACCTTTCTGGCCAATCACGAGATTGCCGACCGTTGCA
AGCTGCCCCGGTCCACGGTCTCGCGCCTGACCTACACCCTCACCAAGCTCGGCTATCTGCATTTCGTCGAGGAGGTGGGC
AAGTATCGGCTGGGCACCCAGCTCGTGGCGCTCAGCACCGTGGCCCTGGGCGGCCTGGACGTGCGCCAGCTCGCCCGCCC
CGCCATGCGCGATCTTGCCAATTTCTCCGGTGCCTCGGTCGGCCTCGCGGTTCGCGACCGCCTGAGCATGCGCTATGTAG
AAAGCCAGCGGGGGCCCGCCGCCATCTCGCTGAACATCGATGTGGGCGTGCGCATGTCCATGGTGCGCTCCTCCATCGGC
CGCGCCTATATCGCTGCCCTCACCGAGGCGGAGCGAGCGCCCTTGTTCGAGGAACTGCGGATGCTCGATCCGCTCGCCTG
GCCCAAGGTGAAGGCCAATCTCGAAAAGGCCATCGAGGATCAGGCGACCATCGGCTGCTGCTGCTCCTTCGGCGAGTGGC
AGGAGAATGTGAGCGCGATCGCCCTGGGCTTTCGGCCCGGCGGCGGCATGCCGCCCATGGCCATCAATTGCGGTGCTCCC
ACCGTCATCACCAGCCCAGAATTCCTCATGGAGGAGGTGCGTCCGCGCCTCATCGAGATGGTGCGTCGGCTGGATGGCGT
GATGGGCGCCTGA

Upstream 100 bases:

>100_bases
TGCGGCGGGGGCCTGCGGCACAGGCCGCCTTTGCCCGTTTCTTCAAGAAGCGGGACGGCGCATCCTGAGCGCTCCTGATC
CGCACCGCCGACCGGAAACC

Downstream 100 bases:

>100_bases
CCCCGAGGACAGACGAATGACCGACGCCCCTTCCGATCTGCCGCTGGCCGGCGTGCGCGTGCTGGACCTCTCCCGCATCC
TCGCCGGTCCCTGGTGCGCC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MMTQPEAQTSDLDEGDAKEDRHFVTALARGLEVLACFKRGETFLANHEIADRCKLPRSTVSRLTYTLTKLGYLHFVEEVG
KYRLGTQLVALSTVALGGLDVRQLARPAMRDLANFSGASVGLAVRDRLSMRYVESQRGPAAISLNIDVGVRMSMVRSSIG
RAYIAALTEAERAPLFEELRMLDPLAWPKVKANLEKAIEDQATIGCCCSFGEWQENVSAIALGFRPGGGMPPMAINCGAP
TVITSPEFLMEEVRPRLIEMVRRLDGVMGA

Sequences:

>Translated_270_residues
MMTQPEAQTSDLDEGDAKEDRHFVTALARGLEVLACFKRGETFLANHEIADRCKLPRSTVSRLTYTLTKLGYLHFVEEVG
KYRLGTQLVALSTVALGGLDVRQLARPAMRDLANFSGASVGLAVRDRLSMRYVESQRGPAAISLNIDVGVRMSMVRSSIG
RAYIAALTEAERAPLFEELRMLDPLAWPKVKANLEKAIEDQATIGCCCSFGEWQENVSAIALGFRPGGGMPPMAINCGAP
TVITSPEFLMEEVRPRLIEMVRRLDGVMGA
>Mature_270_residues
MMTQPEAQTSDLDEGDAKEDRHFVTALARGLEVLACFKRGETFLANHEIADRCKLPRSTVSRLTYTLTKLGYLHFVEEVG
KYRLGTQLVALSTVALGGLDVRQLARPAMRDLANFSGASVGLAVRDRLSMRYVESQRGPAAISLNIDVGVRMSMVRSSIG
RAYIAALTEAERAPLFEELRMLDPLAWPKVKANLEKAIEDQATIGCCCSFGEWQENVSAIALGFRPGGGMPPMAINCGAP
TVITSPEFLMEEVRPRLIEMVRRLDGVMGA

Specific function: Unknown

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=155, Percent_Identity=31.6129032258064, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082359, Length=156, Percent_Identity=25.6410256410256, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29578; Mature: 29578

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTQPEAQTSDLDEGDAKEDRHFVTALARGLEVLACFKRGETFLANHEIADRCKLPRSTV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHCCCHHHH
SRLTYTLTKLGYLHFVEEVGKYRLGTQLVALSTVALGGLDVRQLARPAMRDLANFSGASV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
GLAVRDRLSMRYVESQRGPAAISLNIDVGVRMSMVRSSIGRAYIAALTEAERAPLFEELR
HHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
MLDPLAWPKVKANLEKAIEDQATIGCCCSFGEWQENVSAIALGFRPGGGMPPMAINCGAP
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCHHEEEEEECCCCCCCCEEEECCCC
TVITSPEFLMEEVRPRLIEMVRRLDGVMGA
CEECCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMTQPEAQTSDLDEGDAKEDRHFVTALARGLEVLACFKRGETFLANHEIADRCKLPRSTV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHCCCHHHH
SRLTYTLTKLGYLHFVEEVGKYRLGTQLVALSTVALGGLDVRQLARPAMRDLANFSGASV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
GLAVRDRLSMRYVESQRGPAAISLNIDVGVRMSMVRSSIGRAYIAALTEAERAPLFEELR
HHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
MLDPLAWPKVKANLEKAIEDQATIGCCCSFGEWQENVSAIALGFRPGGGMPPMAINCGAP
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCHHEEEEEECCCCCCCCEEEECCCC
TVITSPEFLMEEVRPRLIEMVRRLDGVMGA
CEECCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]