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The map label for this gene is pkn1 [H]

Identifier: 158424484

GI number: 158424484

Start: 3257677

End: 3258675

Strand: Direct

Name: pkn1 [H]

Synonym: AZC_2860

Alternate gene names: 158424484

Gene position: 3257677-3258675 (Clockwise)

Preceding gene: 158424483

Following gene: 158424485

Centisome position: 60.67

GC content: 69.47

Gene sequence:

>999_bases
ATGGCGGGCGAGGTGCAGGACGCGCGGCATGGCGCGGCTTTGAGCCCGGACGGGCTCGTGGACGCGTCAATGGTCTGGCT
CGCGGGTGCCACGTTTCACATGGGTTCGGACGACCATTATCCCGAGGAAGCTCCCGTCCACCCGGTGAGGGTGGACGGCT
TCTGGATCGACCGTTTTCCGGTCACCAACCGCGACTTTGCCCGCTTTGTGGAAGACACCGGCCATGTCACGGTGGCCGAG
CAGGTGCCCTCCCCCGCCGATTATCCGCTCCTCGATCCCCACCTGCTCGTGGCGGGATCGCTCGTCTTCTCTCCGCCCGA
GGCCCAGCCCGGCCCGGCCGCGTGGGACCAGTGGTGGCGCTTCGTCGAAGGCGCCGACTGGCGCCATCCCAAAGGTCCCG
GCAGCAGCCTCGAAGGGCTCGAGGATCACCCGGTGGTGCACGTGGCCTTCGCCGATGCGCAGGCCTATGCCCGCTGGTGT
CACAAGGCGCTGCCCACCGAGGCCGAGTGGGAATATGCCGCGCGCGGCGGGCTCGACCGCGCGCCTTTCGCCTGGGGCAA
CGAACTGGTGCCCGGCGGCATCCACCGGGCCAACACGTGGCAGGGCGCCTTCCCGGTCGAGAACCTCGCCGAGGACGGCT
TTGCCGGCACCTCACCCGTGGATGCCTTCCCCGCCAACGGCTTCGGCCTCCACGACATGATCGGCAACGTCTGGGAATGG
ACCGACGACTGGTACCAGCCCCGGCACGATCCACCGGCGGCGCGGCCCTGCTGCGTACCGCACAACCCGCGTGGCGGCTC
CGAGGCCGGCAGCCGCCATGCCGACATCCTGGGCGCCGCGTTGCCACGCAAGGTGCTCAAGGGCGGCTCGCATCTGTGCG
CGCCGAACTATTGCCAGCGCTACCGCCCCGCTGCGCGCTCCCCCCAGACCATTGACACCGCCTCGGGACACATCGGCTTC
CGCTGTGTCCGGCGTGGTCCCAAGCAGGAAACGAAATGA

Upstream 100 bases:

>100_bases
TATCCGCTCCGGCGCCTGATCATCTTGCGAAGGCGTTCCGTGCGAACGCGGTCGGCCCCTCCGGCGCCCGGAGCGACTGC
CGACATTCCGGGGGAACGGT

Downstream 100 bases:

>100_bases
CGGATACGCACCGCAACGAGACCGAGGCCGGCCCCAGCCGGCGCGACGTGCTGGCCGGGACGGCCGGTTTCATGGCCGCC
GTGGCGGGCCTATCGGCCCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MAGEVQDARHGAALSPDGLVDASMVWLAGATFHMGSDDHYPEEAPVHPVRVDGFWIDRFPVTNRDFARFVEDTGHVTVAE
QVPSPADYPLLDPHLLVAGSLVFSPPEAQPGPAAWDQWWRFVEGADWRHPKGPGSSLEGLEDHPVVHVAFADAQAYARWC
HKALPTEAEWEYAARGGLDRAPFAWGNELVPGGIHRANTWQGAFPVENLAEDGFAGTSPVDAFPANGFGLHDMIGNVWEW
TDDWYQPRHDPPAARPCCVPHNPRGGSEAGSRHADILGAALPRKVLKGGSHLCAPNYCQRYRPAARSPQTIDTASGHIGF
RCVRRGPKQETK

Sequences:

>Translated_332_residues
MAGEVQDARHGAALSPDGLVDASMVWLAGATFHMGSDDHYPEEAPVHPVRVDGFWIDRFPVTNRDFARFVEDTGHVTVAE
QVPSPADYPLLDPHLLVAGSLVFSPPEAQPGPAAWDQWWRFVEGADWRHPKGPGSSLEGLEDHPVVHVAFADAQAYARWC
HKALPTEAEWEYAARGGLDRAPFAWGNELVPGGIHRANTWQGAFPVENLAEDGFAGTSPVDAFPANGFGLHDMIGNVWEW
TDDWYQPRHDPPAARPCCVPHNPRGGSEAGSRHADILGAALPRKVLKGGSHLCAPNYCQRYRPAARSPQTIDTASGHIGF
RCVRRGPKQETK
>Mature_331_residues
AGEVQDARHGAALSPDGLVDASMVWLAGATFHMGSDDHYPEEAPVHPVRVDGFWIDRFPVTNRDFARFVEDTGHVTVAEQ
VPSPADYPLLDPHLLVAGSLVFSPPEAQPGPAAWDQWWRFVEGADWRHPKGPGSSLEGLEDHPVVHVAFADAQAYARWCH
KALPTEAEWEYAARGGLDRAPFAWGNELVPGGIHRANTWQGAFPVENLAEDGFAGTSPVDAFPANGFGLHDMIGNVWEWT
DDWYQPRHDPPAARPCCVPHNPRGGSEAGSRHADILGAALPRKVLKGGSHLCAPNYCQRYRPAARSPQTIDTASGHIGFR
CVRRGPKQETK

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI38202250, Length=308, Percent_Identity=42.5324675324675, Blast_Score=241, Evalue=5e-64,
Organism=Homo sapiens, GI257470975, Length=308, Percent_Identity=41.2337662337662, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI257470977, Length=307, Percent_Identity=40.0651465798046, Blast_Score=222, Evalue=4e-58,
Organism=Homo sapiens, GI194248088, Length=306, Percent_Identity=39.2156862745098, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI194248087, Length=306, Percent_Identity=37.2549019607843, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI194248090, Length=211, Percent_Identity=44.5497630331754, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI226437577, Length=208, Percent_Identity=42.7884615384615, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI20130397, Length=307, Percent_Identity=42.3452768729642, Blast_Score=224, Evalue=6e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 36285; Mature: 36154

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGEVQDARHGAALSPDGLVDASMVWLAGATFHMGSDDHYPEEAPVHPVRVDGFWIDRFP
CCCCCCHHHCCCCCCCCCCHHHHHHHHHCCEEECCCCCCCCCCCCCCEEEECCEEEECCC
VTNRDFARFVEDTGHVTVAEQVPSPADYPLLDPHLLVAGSLVFSPPEAQPGPAAWDQWWR
CCCHHHHHHHHHCCCEEEHHHCCCCCCCCCCCCHHHHHCCEEECCCCCCCCCHHHHHHHH
FVEGADWRHPKGPGSSLEGLEDHPVVHVAFADAQAYARWCHKALPTEAEWEYAARGGLDR
HHCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCHHHHHCCCCC
APFAWGNELVPGGIHRANTWQGAFPVENLAEDGFAGTSPVDAFPANGFGLHDMIGNVWEW
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
TDDWYQPRHDPPAARPCCVPHNPRGGSEAGSRHADILGAALPRKVLKGGSHLCAPNYCQR
CHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
YRPAARSPQTIDTASGHIGFRCVRRGPKQETK
CCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AGEVQDARHGAALSPDGLVDASMVWLAGATFHMGSDDHYPEEAPVHPVRVDGFWIDRFP
CCCCCHHHCCCCCCCCCCHHHHHHHHHCCEEECCCCCCCCCCCCCCEEEECCEEEECCC
VTNRDFARFVEDTGHVTVAEQVPSPADYPLLDPHLLVAGSLVFSPPEAQPGPAAWDQWWR
CCCHHHHHHHHHCCCEEEHHHCCCCCCCCCCCCHHHHHCCEEECCCCCCCCCHHHHHHHH
FVEGADWRHPKGPGSSLEGLEDHPVVHVAFADAQAYARWCHKALPTEAEWEYAARGGLDR
HHCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCHHHHHCCCCC
APFAWGNELVPGGIHRANTWQGAFPVENLAEDGFAGTSPVDAFPANGFGLHDMIGNVWEW
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
TDDWYQPRHDPPAARPCCVPHNPRGGSEAGSRHADILGAALPRKVLKGGSHLCAPNYCQR
CHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
YRPAARSPQTIDTASGHIGFRCVRRGPKQETK
CCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]