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The map label for this gene is yyaJ [H]

Identifier: 158424482

GI number: 158424482

Start: 3254628

End: 3256130

Strand: Direct

Name: yyaJ [H]

Synonym: AZC_2858

Alternate gene names: 158424482

Gene position: 3254628-3256130 (Clockwise)

Preceding gene: 158424481

Following gene: 158424483

Centisome position: 60.61

GC content: 66.67

Gene sequence:

>1503_bases
GTGCCGGATCGGCCCGCACGGGCCGGTCCGGCGCAGCTCGCCGACATTCCGGAGGACCCCGCAGGTCCCCGGCAAAAAGA
AAAGACGACACCCGTTCCTGGAGGAAAGCCCATGCTGATGCAGAGGCCCCGCGACATTGCGCGCGGGCAGACCCCATCGC
TCGACCGGCAGGCGGATATCAGCGCCCGGCTGGAACGCCTGCCCATCACCCGCCGCGTCTTCTGGACCCGCAACATCATC
GGTGCGGCCACCTTCTTTGATGGCTACACCGTCATCGCCATCGCCTATGCAATGCCCGTTCTTGTCCGCGAATGGGGCCT
CAAGCCCGAGCAGACGGGCATGATCCTGTCCATGGGCTATCTCGGCCAGCTCATCGGCGCGGTGTTCTTCGGCTGGCTGG
CCGAGCGCATAGGCCGCCTCAGCGTGCTGCTTTTCACTATCCTGCTGTTCGTCAGCATGGATGTCGCCTGCCTGTTCGCC
TGGGGCGCCGGTTCGATGATGCTCTTCCGCTTCATCCAAGGCATCGGCACCGGCGGCGAGGTGCCGGTGGCGAGCGCCTA
CATCAACGAATACATCGGCTCGAAGGGGCGCGGCCGCTTCTTCCTGCTCTATGAGGTCATGTTCCTCTTCGGCCTCGTGG
GCGCGGGCCTCATCGCGCGGGCGCTGGTGCCGGTCTATGGCTGGGAGGCCATGTTCCTCGTCGGGCTCGTGCCGGCCGCC
ATCCTGATCCCGCTGCGCTTCTTCATGAAGGAATCTCCGCGCTGGCTGGCAGCGAAGGGCCGTTACGAGGAAGCCGACCG
GATCGTGAGCGATCTGGAGCGCAGCGCCGAGGCCGCGGGCCACAAGCTCGCGATGCCGCAGCCGGTTCCCATGAAGCAGA
GCGAACAGGGCGGCCTCAGGGAGCTGTTCTCCGGCATCTATCGCCGGCGCACGCTGACCATCTGGTCCATGTGGTTCTGC
TCATATCTGGTGGCGAACGGCATGATCGCCTGGCTGCCGACGCTCTATCGCCAGACCTTCAACCTGCCGCTGGAAACCGC
CCTGCTGTACGGCCTGCTGACGTCGGTCGCCGGCGTGGTGGCCTCCATCGCCTGCGCCCTGCTGATCGACAAGGTGGGCC
GCAAGCGCTGGTACACGGCCGCCTTCCTCTGCGCGCCGCTGCCGCTTCTGGCGCTGGCCTACATGGGCGCCACCTCGCCG
ATGGAAGTCCTCCTGCTGGCCGGGCTCGCCTATGCCATCGTGCAGACCATCACCTTCTCGCTCTATCTCTACTCGGCCGA
GCTCTATCCGACGCGCCTGCGGGCGCTGGGCACCGGGCTCGGGAGCGCCTGGCTGCGGCTCGGCTCGTCGGCCGGCCCCA
TCGTCGTCGGCACCATCATGGGCGCGGCGGGCATCCAGTATGTGTTCGCGGCCTTCGCCGGGGTTCTGGTCATCGGGGCG
CTGGTGACCATGCTCTTCGCCATCGAGACGAAGGGCCGTGTGCTGGAGGAACTGTCTCCATAA

Upstream 100 bases:

>100_bases
CCGCGCCGCCGTGAAGGCCGCCGGCATCGAAGTGGTGTCGAACGCCATCGCGGCCTGACCCCGAGGCGCGCCAACGCCTC
GCTGATTTGGGGAAGAGGGA

Downstream 100 bases:

>100_bases
GGAGCCAGACGGGACGCGCCGGGGCGGTTCAGCCCGCCCGGCGCCGGCCCTGATGGCCAGCGAAGCGCCCCCTTTCGCAA
ACCTCACCTCCGCAAGACGT

Product: permeases

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MPDRPARAGPAQLADIPEDPAGPRQKEKTTPVPGGKPMLMQRPRDIARGQTPSLDRQADISARLERLPITRRVFWTRNII
GAATFFDGYTVIAIAYAMPVLVREWGLKPEQTGMILSMGYLGQLIGAVFFGWLAERIGRLSVLLFTILLFVSMDVACLFA
WGAGSMMLFRFIQGIGTGGEVPVASAYINEYIGSKGRGRFFLLYEVMFLFGLVGAGLIARALVPVYGWEAMFLVGLVPAA
ILIPLRFFMKESPRWLAAKGRYEEADRIVSDLERSAEAAGHKLAMPQPVPMKQSEQGGLRELFSGIYRRRTLTIWSMWFC
SYLVANGMIAWLPTLYRQTFNLPLETALLYGLLTSVAGVVASIACALLIDKVGRKRWYTAAFLCAPLPLLALAYMGATSP
MEVLLLAGLAYAIVQTITFSLYLYSAELYPTRLRALGTGLGSAWLRLGSSAGPIVVGTIMGAAGIQYVFAAFAGVLVIGA
LVTMLFAIETKGRVLEELSP

Sequences:

>Translated_500_residues
MPDRPARAGPAQLADIPEDPAGPRQKEKTTPVPGGKPMLMQRPRDIARGQTPSLDRQADISARLERLPITRRVFWTRNII
GAATFFDGYTVIAIAYAMPVLVREWGLKPEQTGMILSMGYLGQLIGAVFFGWLAERIGRLSVLLFTILLFVSMDVACLFA
WGAGSMMLFRFIQGIGTGGEVPVASAYINEYIGSKGRGRFFLLYEVMFLFGLVGAGLIARALVPVYGWEAMFLVGLVPAA
ILIPLRFFMKESPRWLAAKGRYEEADRIVSDLERSAEAAGHKLAMPQPVPMKQSEQGGLRELFSGIYRRRTLTIWSMWFC
SYLVANGMIAWLPTLYRQTFNLPLETALLYGLLTSVAGVVASIACALLIDKVGRKRWYTAAFLCAPLPLLALAYMGATSP
MEVLLLAGLAYAIVQTITFSLYLYSAELYPTRLRALGTGLGSAWLRLGSSAGPIVVGTIMGAAGIQYVFAAFAGVLVIGA
LVTMLFAIETKGRVLEELSP
>Mature_499_residues
PDRPARAGPAQLADIPEDPAGPRQKEKTTPVPGGKPMLMQRPRDIARGQTPSLDRQADISARLERLPITRRVFWTRNIIG
AATFFDGYTVIAIAYAMPVLVREWGLKPEQTGMILSMGYLGQLIGAVFFGWLAERIGRLSVLLFTILLFVSMDVACLFAW
GAGSMMLFRFIQGIGTGGEVPVASAYINEYIGSKGRGRFFLLYEVMFLFGLVGAGLIARALVPVYGWEAMFLVGLVPAAI
LIPLRFFMKESPRWLAAKGRYEEADRIVSDLERSAEAAGHKLAMPQPVPMKQSEQGGLRELFSGIYRRRTLTIWSMWFCS
YLVANGMIAWLPTLYRQTFNLPLETALLYGLLTSVAGVVASIACALLIDKVGRKRWYTAAFLCAPLPLLALAYMGATSPM
EVLLLAGLAYAIVQTITFSLYLYSAELYPTRLRALGTGLGSAWLRLGSSAGPIVVGTIMGAAGIQYVFAAFAGVLVIGAL
VTMLFAIETKGRVLEELSP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=443, Percent_Identity=25.5079006772009, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI213021148, Length=456, Percent_Identity=25.6578947368421, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI166064021, Length=415, Percent_Identity=27.4698795180723, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI7662270, Length=303, Percent_Identity=26.4026402640264, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI4506999, Length=476, Percent_Identity=25, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI31542327, Length=377, Percent_Identity=27.8514588859416, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI216548223, Length=304, Percent_Identity=25.3289473684211, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI302148518, Length=449, Percent_Identity=24.4988864142539, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4507005, Length=386, Percent_Identity=26.9430051813472, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI23510410, Length=322, Percent_Identity=25.4658385093168, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI11415038, Length=408, Percent_Identity=25.4901960784314, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI262399383, Length=262, Percent_Identity=26.7175572519084, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI166197673, Length=359, Percent_Identity=26.4623955431755, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI24497490, Length=428, Percent_Identity=24.7663551401869, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI24497476, Length=372, Percent_Identity=24.7311827956989, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI20070188, Length=372, Percent_Identity=24.7311827956989, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI73695465, Length=257, Percent_Identity=25.6809338521401, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI8923870, Length=401, Percent_Identity=25.1870324189526, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI87082159, Length=438, Percent_Identity=27.3972602739726, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1786229, Length=420, Percent_Identity=24.7619047619048, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1789207, Length=431, Percent_Identity=25.9860788863109, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788068, Length=463, Percent_Identity=24.8380129589633, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788074, Length=455, Percent_Identity=24.6153846153846, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1789312, Length=430, Percent_Identity=25.3488372093023, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87081723, Length=393, Percent_Identity=29.0076335877863, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI87082231, Length=447, Percent_Identity=23.489932885906, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87082404, Length=418, Percent_Identity=22.9665071770335, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1790463, Length=425, Percent_Identity=24.4705882352941, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI32564663, Length=463, Percent_Identity=23.5421166306695, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI71989531, Length=356, Percent_Identity=25, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71989525, Length=356, Percent_Identity=25, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71986689, Length=357, Percent_Identity=21.8487394957983, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI193202825, Length=357, Percent_Identity=21.8487394957983, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565978, Length=326, Percent_Identity=26.0736196319018, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17560496, Length=403, Percent_Identity=24.317617866005, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71996338, Length=452, Percent_Identity=22.5663716814159, Blast_Score=68, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6320745, Length=411, Percent_Identity=25.3041362530414, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19922616, Length=515, Percent_Identity=25.0485436893204, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI19922874, Length=412, Percent_Identity=24.0291262135922, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24640198, Length=479, Percent_Identity=22.964509394572, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24640196, Length=479, Percent_Identity=22.964509394572, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24640200, Length=479, Percent_Identity=22.964509394572, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21355657, Length=358, Percent_Identity=27.9329608938547, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI62484254, Length=386, Percent_Identity=25.1295336787565, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24668440, Length=406, Percent_Identity=25.1231527093596, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI19922134, Length=436, Percent_Identity=26.3761467889908, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24649622, Length=432, Percent_Identity=24.0740740740741, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573099, Length=300, Percent_Identity=22.3333333333333, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28573101, Length=300, Percent_Identity=22.3333333333333, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21357295, Length=272, Percent_Identity=26.4705882352941, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI161078056, Length=272, Percent_Identity=26.4705882352941, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI161077756, Length=429, Percent_Identity=22.3776223776224, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI28573097, Length=224, Percent_Identity=25.4464285714286, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17737451, Length=432, Percent_Identity=26.1574074074074, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24652312, Length=432, Percent_Identity=26.1574074074074, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24649618, Length=372, Percent_Identity=23.9247311827957, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45549297, Length=472, Percent_Identity=22.6694915254237, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24649616, Length=386, Percent_Identity=25.1295336787565, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI161078338, Length=358, Percent_Identity=27.6536312849162, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24647365, Length=358, Percent_Identity=27.6536312849162, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 54633; Mature: 54502

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCHHHHHCCC
>Mature Secondary Structure 
PDRPARAGPAQLADIPEDPAGPRQKEKTTPVPGGKPMLMQRPRDIARGQTPSLDRQADI
CCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHCCCCCCCCCHHHH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HHHHHHHHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]