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The map label for this gene is lysR [H]

Identifier: 158424407

GI number: 158424407

Start: 3163108

End: 3164037

Strand: Direct

Name: lysR [H]

Synonym: AZC_2783

Alternate gene names: 158424407

Gene position: 3163108-3164037 (Clockwise)

Preceding gene: 158424403

Following gene: 158424413

Centisome position: 58.91

GC content: 68.71

Gene sequence:

>930_bases
ATGCGCTACGATCTCAATCTCCTGCCGGTTTTCGTGACCCTCATGGAGGAGCGCAGCGTCACACGAGCCGCCGAACGACT
CGGCATGACGCAGCCGGCGCTGTCCAACGCTCTGGCGCGCCTGCGCGTGGTGATGCGCGATCCCCTGTTCATCCGCGAAC
GTTACGGCATCCAGCCGACGCCTTTGGCGCTGGAACTGGCGCCCGTGCTGCGGGCCGCGCTCGCGCAGATCGACGAGGTG
GTCCATGGCCAGCAGGCCTTCGAGCCGGCCGAGGCCGAGCGGCTGATGACGATCGCGCCGAACTCCTATGCGGAGTTTGC
GCTGATCCCTACCGTCGTGGCGCGGCTCCGGGCGGTTGCGCCCGGCATCAGCCTGCGCCTGACGCCCTATGGCAGCGACC
TGTCCGAAACCGGGGTCATCTCCGGGACCACGGCCATGGCCATCGGCCGCTTCGTGGAGGTTCAGGACAATCTCGTGGTG
CAGCACCTGATGGACGATGGCCTCGCCTGCGTCGTGCGGGCCGACCATCCGGACGTGGGCGATGTCCTGACGCGGGAGAC
TTACGAGCGCCTGCGGCATGTCAATGTGCTGCCGCCCGGCCGCCTGCGTGCCGGCCTGTTCCAGGTGCTGGAGCGCCATG
GCCTGAAGCGGGACGTGGCGGTGTCCGTCACCCACTTCCTGGCCGTTCCCGAGATGATCGCGGTGACGGATTATTGCGCC
ACCCTGCCCCGCCTCATCTGCGCGCGCCTCGCACATGATACGCGGCTGAAGTTCGTTCCGGCCCCGGTGGACCTCGGCAC
CTTTCCCGTCGACATGGCCTGGCACGTGCGCTACCGGCACGATCCCGCCCACCGCTGGCTGCGCACGCTCATCGCAGAGG
TGGCACGGGAGGCGGCAGGAACCGCCCCCGCACCGGAGGATGCGCCCTGA

Upstream 100 bases:

>100_bases
GATCAGGTGACCCGGCTTGGATGGGCAGACCATGCGCCATACGAACATATTCTAGAAATTTATTTCTATGAGATAAGATA
TTCGCATGAGATTATAACTC

Downstream 100 bases:

>100_bases
AGAGGGCCGGGTCGGGACAAACGCTTCTGCATCTCCCGTGACGCAGGCGCCGTGCCCAGACCTGGACGCACGGCGCCCGC
AATTGCAGGGCGCCCCCGAC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MRYDLNLLPVFVTLMEERSVTRAAERLGMTQPALSNALARLRVVMRDPLFIRERYGIQPTPLALELAPVLRAALAQIDEV
VHGQQAFEPAEAERLMTIAPNSYAEFALIPTVVARLRAVAPGISLRLTPYGSDLSETGVISGTTAMAIGRFVEVQDNLVV
QHLMDDGLACVVRADHPDVGDVLTRETYERLRHVNVLPPGRLRAGLFQVLERHGLKRDVAVSVTHFLAVPEMIAVTDYCA
TLPRLICARLAHDTRLKFVPAPVDLGTFPVDMAWHVRYRHDPAHRWLRTLIAEVAREAAGTAPAPEDAP

Sequences:

>Translated_309_residues
MRYDLNLLPVFVTLMEERSVTRAAERLGMTQPALSNALARLRVVMRDPLFIRERYGIQPTPLALELAPVLRAALAQIDEV
VHGQQAFEPAEAERLMTIAPNSYAEFALIPTVVARLRAVAPGISLRLTPYGSDLSETGVISGTTAMAIGRFVEVQDNLVV
QHLMDDGLACVVRADHPDVGDVLTRETYERLRHVNVLPPGRLRAGLFQVLERHGLKRDVAVSVTHFLAVPEMIAVTDYCA
TLPRLICARLAHDTRLKFVPAPVDLGTFPVDMAWHVRYRHDPAHRWLRTLIAEVAREAAGTAPAPEDAP
>Mature_309_residues
MRYDLNLLPVFVTLMEERSVTRAAERLGMTQPALSNALARLRVVMRDPLFIRERYGIQPTPLALELAPVLRAALAQIDEV
VHGQQAFEPAEAERLMTIAPNSYAEFALIPTVVARLRAVAPGISLRLTPYGSDLSETGVISGTTAMAIGRFVEVQDNLVV
QHLMDDGLACVVRADHPDVGDVLTRETYERLRHVNVLPPGRLRAGLFQVLERHGLKRDVAVSVTHFLAVPEMIAVTDYCA
TLPRLICARLAHDTRLKFVPAPVDLGTFPVDMAWHVRYRHDPAHRWLRTLIAEVAREAAGTAPAPEDAP

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=295, Percent_Identity=27.1186440677966, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1790147, Length=307, Percent_Identity=28.6644951140065, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87081766, Length=274, Percent_Identity=25.5474452554745, Blast_Score=85, Evalue=5e-18,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34189; Mature: 34189

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYDLNLLPVFVTLMEERSVTRAAERLGMTQPALSNALARLRVVMRDPLFIRERYGIQPT
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCC
PLALELAPVLRAALAQIDEVVHGQQAFEPAEAERLMTIAPNSYAEFALIPTVVARLRAVA
CHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHEEEECCCCCHHHHHHHHHHHHHHHHC
PGISLRLTPYGSDLSETGVISGTTAMAIGRFVEVQDNLVVQHLMDDGLACVVRADHPDVG
CCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHH
DVLTRETYERLRHVNVLPPGRLRAGLFQVLERHGLKRDVAVSVTHFLAVPEMIAVTDYCA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TLPRLICARLAHDTRLKFVPAPVDLGTFPVDMAWHVRYRHDPAHRWLRTLIAEVAREAAG
HHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCC
TAPAPEDAP
CCCCCCCCC
>Mature Secondary Structure
MRYDLNLLPVFVTLMEERSVTRAAERLGMTQPALSNALARLRVVMRDPLFIRERYGIQPT
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCC
PLALELAPVLRAALAQIDEVVHGQQAFEPAEAERLMTIAPNSYAEFALIPTVVARLRAVA
CHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHEEEECCCCCHHHHHHHHHHHHHHHHC
PGISLRLTPYGSDLSETGVISGTTAMAIGRFVEVQDNLVVQHLMDDGLACVVRADHPDVG
CCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHH
DVLTRETYERLRHVNVLPPGRLRAGLFQVLERHGLKRDVAVSVTHFLAVPEMIAVTDYCA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TLPRLICARLAHDTRLKFVPAPVDLGTFPVDMAWHVRYRHDPAHRWLRTLIAEVAREAAG
HHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCC
TAPAPEDAP
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]