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The map label for this gene is ompR [H]

Identifier: 158424377

GI number: 158424377

Start: 3128684

End: 3129406

Strand: Direct

Name: ompR [H]

Synonym: AZC_2753

Alternate gene names: 158424377

Gene position: 3128684-3129406 (Clockwise)

Preceding gene: 158424372

Following gene: 158424378

Centisome position: 58.26

GC content: 68.33

Gene sequence:

>723_bases
GTGGAAAACGCGCCGCATGTACTCGTGGTCGACGATGACCAGGAAATCCGCAAGCTTCTCGCGCGCTATCTTCTCAGCCA
GGGCTTCCGGACCACGGTCGCCGCCAGCGGCCGCGAGATGGAGGAGTGCCTCGCCTCCAGCCGCTTCGACATGGTGGTTC
TCGACCTGATGCTGCCCGACGCCTCGGGGCTCGATCTGTGCCGCGCCCTGCGCGCTCGTTCGCGCCTGCCGATCATCCTG
CTGACGGCGTTGAAGGAGGATGTGGACCGCATCATCGGGCTTGAGATCGGGGCGGACGACTATCTCGGAAAGCCCTTCAA
TCCCCGCGAGCTGGTGGCCCGCATCCGCGCCGTGCTGCGGCGGGCGACGGAGCGCGAGGAACCCGCGGCGCCGGGTGCGA
TCTATCGTTTCGCCGGCTTCACCGCCGATCAGGGCACACGGCAGGTCACCAGCGAGACGGGCGCGGAAGTGGCTCTCACA
GCCGCGGAGTTCGACCTGCTGGTGGCCTTCCTCGAACGCCCCGGCCGCATCCTGTCGCGCGACCAGTTGCTCGACATCAC
GCAGGGGCGCGAGGCCGGCCCCTTTGACCGCTCCATCGACGTGCTGGTCAGCCGCCTGCGGCGCAAGCTCGGGGACGCCG
GCAGCTTCCAGATCCTGAAGACCCAGCGCAACGGCGGCTATCAGCTCTCCGTGCGCGTCGAGGCGCTGAAGCCCTCCGCA
TGA

Upstream 100 bases:

>100_bases
GCAATGCTCGGATGCACTCTGGCGAAGGCACGAGGCCGCGCGTAGCGTAATCAGGTTTCCCGACACAGGGCTTGGAAACC
GAAGCAGGACAGGACGCCGA

Downstream 100 bases:

>100_bases
ATTCGCTCCGCACCAAGCTCATCGCGCTTCTCGTCACCGCGCTGGTGGTGGTGATCATCATCGCGACGGTCGTCTTCTTC
TACCTGGTCGCGCCCCGCCC

Product: IMP dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MENAPHVLVVDDDQEIRKLLARYLLSQGFRTTVAASGREMEECLASSRFDMVVLDLMLPDASGLDLCRALRARSRLPIIL
LTALKEDVDRIIGLEIGADDYLGKPFNPRELVARIRAVLRRATEREEPAAPGAIYRFAGFTADQGTRQVTSETGAEVALT
AAEFDLLVAFLERPGRILSRDQLLDITQGREAGPFDRSIDVLVSRLRRKLGDAGSFQILKTQRNGGYQLSVRVEALKPSA

Sequences:

>Translated_240_residues
MENAPHVLVVDDDQEIRKLLARYLLSQGFRTTVAASGREMEECLASSRFDMVVLDLMLPDASGLDLCRALRARSRLPIIL
LTALKEDVDRIIGLEIGADDYLGKPFNPRELVARIRAVLRRATEREEPAAPGAIYRFAGFTADQGTRQVTSETGAEVALT
AAEFDLLVAFLERPGRILSRDQLLDITQGREAGPFDRSIDVLVSRLRRKLGDAGSFQILKTQRNGGYQLSVRVEALKPSA
>Mature_240_residues
MENAPHVLVVDDDQEIRKLLARYLLSQGFRTTVAASGREMEECLASSRFDMVVLDLMLPDASGLDLCRALRARSRLPIIL
LTALKEDVDRIIGLEIGADDYLGKPFNPRELVARIRAVLRRATEREEPAAPGAIYRFAGFTADQGTRQVTSETGAEVALT
AAEFDLLVAFLERPGRILSRDQLLDITQGREAGPFDRSIDVLVSRLRRKLGDAGSFQILKTQRNGGYQLSVRVEALKPSA

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=47.4137931034483, Blast_Score=192, Evalue=1e-50,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=40.2597402597403, Blast_Score=162, Evalue=1e-41,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=36.0169491525424, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI1788394, Length=209, Percent_Identity=39.7129186602871, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=41.7777777777778, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=36.9565217391304, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=38.6666666666667, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=37.2294372294372, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=35.3982300884956, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1786911, Length=205, Percent_Identity=37.5609756097561, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=34.061135371179, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=32.4444444444444, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=30.0448430493274, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1787375, Length=231, Percent_Identity=31.1688311688312, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1790299, Length=124, Percent_Identity=37.0967741935484, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788550, Length=122, Percent_Identity=31.9672131147541, Blast_Score=70, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26551; Mature: 26551

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENAPHVLVVDDDQEIRKLLARYLLSQGFRTTVAASGREMEECLASSRFDMVVLDLMLPD
CCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHCCCCCEEEEEECCCC
ASGLDLCRALRARSRLPIILLTALKEDVDRIIGLEIGADDYLGKPFNPRELVARIRAVLR
CCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHH
RATEREEPAAPGAIYRFAGFTADQGTRQVTSETGAEVALTAAEFDLLVAFLERPGRILSR
HHHHCCCCCCCCHHHHHCCCCCCCCHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCHHCH
DQLLDITQGREAGPFDRSIDVLVSRLRRKLGDAGSFQILKTQRNGGYQLSVRVEALKPSA
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEEEECCCCC
>Mature Secondary Structure
MENAPHVLVVDDDQEIRKLLARYLLSQGFRTTVAASGREMEECLASSRFDMVVLDLMLPD
CCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHCCCCCEEEEEECCCC
ASGLDLCRALRARSRLPIILLTALKEDVDRIIGLEIGADDYLGKPFNPRELVARIRAVLR
CCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHH
RATEREEPAAPGAIYRFAGFTADQGTRQVTSETGAEVALTAAEFDLLVAFLERPGRILSR
HHHHCCCCCCCCHHHHHCCCCCCCCHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCHHCH
DQLLDITQGREAGPFDRSIDVLVSRLRRKLGDAGSFQILKTQRNGGYQLSVRVEALKPSA
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]