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The map label for this gene is lysR [H]

Identifier: 158424295

GI number: 158424295

Start: 3029809

End: 3030702

Strand: Reverse

Name: lysR [H]

Synonym: AZC_2671

Alternate gene names: 158424295

Gene position: 3030702-3029809 (Counterclockwise)

Preceding gene: 158424302

Following gene: 158424293

Centisome position: 56.44

GC content: 67.11

Gene sequence:

>894_bases
ATGCGCATCAATTTCGAGCTGCTGGACCTGCGCGCCTTCCTGGCGGTGATTGACCATGGCGGTTTTCACCGCGCGGCCGA
GGTGCTGAACCTCTCCCAACCGGCGCTGACCCGGCGGGTGCAGGCGCTGGAGGCGACGGTCGGTGTCCCGCTGCTGGAGC
GCACGACCCGACGCGTGGCACTCACCTCGGCTGGCCGTTCCTTCGCGCCGCTCGCCCGCCGGCTCATCGGGGATCTGGAG
GAATCGCTGCTCGGCATCGCCGGGGTCGGCGGGCGGCAGGGTGGCCAGATCACGCTTGCTTGCGTGCCCACGGCGGTGGT
CTACTTCCTGCCCGAAGCCATCGAGCGCTTCGCCGCCGAATTTCCGCGCATCCGCTTCCGCATCCTCGACCTCTCGGCCA
ATGACGGGCTGGAGGCGGTGCGCACGGGCGAGGCTGAGTTCGGCATCAATCTGGTGGGCAGTTCCGACCCCGATCTCACC
TTCACGCCGCTGATCGAGGATCCCTTCGTGCTGGCCTGTCGCTCCGACCACCGTTTGGCCAAGCTGACCTCGGTCTCATG
GAAGGACTTGCAGGGGGAGCCTCTGATCGGCGTGAGCCGGGCAAGCGGCAACCGGCTGACGCTCGAGAATGCGCTGGCCG
GGGCGAAGGTGCAGCTCGATTTTCAGTATGAGGTGAACCATCTCGCAACTTCGCTAGGTCTGGTGGAGCGCGGCCTCGGC
GTCTCGGTGCTTCCGAAGATGGCGACCCCCAGTGATCACCCGGTCATCGTTACCAAGCCCATCAAGGCGCCGGTCGTGCG
GCGCACCATCGGGCTCGTGGAGCGCCGCACCTCGCGGCTGTCCCCGGCGGCCAAGAAGTTCCGCGACATGCTGGTGGAGC
ACCTGAACCCATAG

Upstream 100 bases:

>100_bases
TGGACTCTCTCCGAAAGGCGTATCAGTGGGCTCGATTGATGCTATCCTTCACAAAATCGGCCGTTCCGTTAAATGCAAAG
ATTTTCAGGTTTGATGTGAG

Downstream 100 bases:

>100_bases
GAAATCGGATACGGCACCCGCCGGCTTTCAGGTGGCTGCACGGGCCCGTGTCGAGCGGGCGAACAGTTCCGCCACCCAGT
CCACGAACACGCGCAGGCGG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MRINFELLDLRAFLAVIDHGGFHRAAEVLNLSQPALTRRVQALEATVGVPLLERTTRRVALTSAGRSFAPLARRLIGDLE
ESLLGIAGVGGRQGGQITLACVPTAVVYFLPEAIERFAAEFPRIRFRILDLSANDGLEAVRTGEAEFGINLVGSSDPDLT
FTPLIEDPFVLACRSDHRLAKLTSVSWKDLQGEPLIGVSRASGNRLTLENALAGAKVQLDFQYEVNHLATSLGLVERGLG
VSVLPKMATPSDHPVIVTKPIKAPVVRRTIGLVERRTSRLSPAAKKFRDMLVEHLNP

Sequences:

>Translated_297_residues
MRINFELLDLRAFLAVIDHGGFHRAAEVLNLSQPALTRRVQALEATVGVPLLERTTRRVALTSAGRSFAPLARRLIGDLE
ESLLGIAGVGGRQGGQITLACVPTAVVYFLPEAIERFAAEFPRIRFRILDLSANDGLEAVRTGEAEFGINLVGSSDPDLT
FTPLIEDPFVLACRSDHRLAKLTSVSWKDLQGEPLIGVSRASGNRLTLENALAGAKVQLDFQYEVNHLATSLGLVERGLG
VSVLPKMATPSDHPVIVTKPIKAPVVRRTIGLVERRTSRLSPAAKKFRDMLVEHLNP
>Mature_297_residues
MRINFELLDLRAFLAVIDHGGFHRAAEVLNLSQPALTRRVQALEATVGVPLLERTTRRVALTSAGRSFAPLARRLIGDLE
ESLLGIAGVGGRQGGQITLACVPTAVVYFLPEAIERFAAEFPRIRFRILDLSANDGLEAVRTGEAEFGINLVGSSDPDLT
FTPLIEDPFVLACRSDHRLAKLTSVSWKDLQGEPLIGVSRASGNRLTLENALAGAKVQLDFQYEVNHLATSLGLVERGLG
VSVLPKMATPSDHPVIVTKPIKAPVVRRTIGLVERRTSRLSPAAKKFRDMLVEHLNP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=288, Percent_Identity=46.875, Blast_Score=278, Evalue=3e-76,
Organism=Escherichia coli, GI1788748, Length=296, Percent_Identity=33.7837837837838, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI157672245, Length=281, Percent_Identity=29.1814946619217, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1790399, Length=274, Percent_Identity=29.1970802919708, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1788887, Length=293, Percent_Identity=28.3276450511945, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787879, Length=297, Percent_Identity=27.2727272727273, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787601, Length=195, Percent_Identity=30.2564102564103, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI2367136, Length=279, Percent_Identity=26.5232974910394, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790208, Length=145, Percent_Identity=32.4137931034483, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788297, Length=246, Percent_Identity=27.6422764227642, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788481, Length=289, Percent_Identity=24.2214532871972, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1789204, Length=239, Percent_Identity=25.5230125523013, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787530, Length=300, Percent_Identity=24.3333333333333, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787589, Length=244, Percent_Identity=27.8688524590164, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87081904, Length=177, Percent_Identity=30.5084745762712, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790783, Length=310, Percent_Identity=25.8064516129032, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1789506, Length=289, Percent_Identity=22.1453287197232, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87082132, Length=248, Percent_Identity=23.7903225806452, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1788296, Length=213, Percent_Identity=24.4131455399061, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32305; Mature: 32305

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRINFELLDLRAFLAVIDHGGFHRAAEVLNLSQPALTRRVQALEATVGVPLLERTTRRVA
CEEEHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHEEE
LTSAGRSFAPLARRLIGDLEESLLGIAGVGGRQGGQITLACVPTAVVYFLPEAIERFAAE
EECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
FPRIRFRILDLSANDGLEAVRTGEAEFGINLVGSSDPDLTFTPLIEDPFVLACRSDHRLA
CCCEEEEEEEECCCCCHHHHCCCCCCCCEEEECCCCCCEEEEECCCCCEEEEECCCCCEE
KLTSVSWKDLQGEPLIGVSRASGNRLTLENALAGAKVQLDFQYEVNHLATSLGLVERGLG
HHHCCCCCCCCCCCCEEEECCCCCEEEHHHCCCCCEEEEEEEEHHHHHHHHHHHHHCCCC
VSVLPKMATPSDHPVIVTKPIKAPVVRRTIGLVERRTSRLSPAAKKFRDMLVEHLNP
CEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRINFELLDLRAFLAVIDHGGFHRAAEVLNLSQPALTRRVQALEATVGVPLLERTTRRVA
CEEEHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHEEE
LTSAGRSFAPLARRLIGDLEESLLGIAGVGGRQGGQITLACVPTAVVYFLPEAIERFAAE
EECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
FPRIRFRILDLSANDGLEAVRTGEAEFGINLVGSSDPDLTFTPLIEDPFVLACRSDHRLA
CCCEEEEEEEECCCCCHHHHCCCCCCCCEEEECCCCCCEEEEECCCCCEEEEECCCCCEE
KLTSVSWKDLQGEPLIGVSRASGNRLTLENALAGAKVQLDFQYEVNHLATSLGLVERGLG
HHHCCCCCCCCCCCCEEEECCCCCEEEHHHCCCCCEEEEEEEEHHHHHHHHHHHHHCCCC
VSVLPKMATPSDHPVIVTKPIKAPVVRRTIGLVERRTSRLSPAAKKFRDMLVEHLNP
CEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]