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The map label for this gene is dapA [H]

Identifier: 158424273

GI number: 158424273

Start: 3001551

End: 3002660

Strand: Direct

Name: dapA [H]

Synonym: AZC_2649

Alternate gene names: 158424273

Gene position: 3001551-3002660 (Clockwise)

Preceding gene: 158424271

Following gene: 158424274

Centisome position: 55.9

GC content: 63.42

Gene sequence:

>1110_bases
ATGACAGGGCGGCGACACGCTATTGACAGGGTGCAGGATGCGGGTCAGATTTCAAACAATTATTTGAAAAGCAGCAGCAC
AGAGCTGAATTCACGGCTCCGTCTGCTTGCTCGACGGCCCATTTCTTCCCGAAGCGCAGGCGGGCAGCAGGCCCGCAGAG
GCACGAGGCCACCCATGCAGAAGATCACCGGTTCCTTCGTCGCGATCGTGACGCCCTTCAACAAGGACGGCTCGGTGGAT
TTCGTCGCCTTCCGCGAGCTTCTGAAGTTCCAGGAAGACAACGGCACCGCCGCGATCCTCATCATGGGCTCCACGGGCGA
GACCTCGATGCTCTCGGCTGAGGAGAAGAAGAAGGTCATCGTCGAGACCGCCAAGATGAAGACGGCGAAGATGCCCCTCT
TCTACGGCTGCACCGGCAACAACACCGAAACCACCATCGAGAACGTGCGCTTCGCCAAGGACAATGGCGCGGACGGCGCC
ATTCTCGCGGCCCCCGCTTATATCTGCGCACCGGAAGCGGACATCGAGGGCTATTTCCTCGACGTGGCGGATGCCACCGA
CCTGCCGCTCGGCATCTATAACAACCCGCCCCGCGTGAAGAGCGACCTGCACTGGGACAACCTGCTGCGCATCTTCAAGC
ACCCGAACTATGTGATCCATAAGGAATCCACCACCCGCGTCGGCCAGGTGGCGCAGGTGCTCGCCGCCCGTCCGGACGTC
TCGGTGATGTGCTGCGACAGCCCGAACCTCGGCCTTGTGGTGCCCACCATGAGCCTCGGCGGCCATGGCACGGCCAACAT
GACCGGCAACATCGCTCCGGCCGAACTCGTCGCCATTTCCCGCCCGTGGAACGGCGATGAGGGCGCGGCGGCGTTCAAGG
AGGCCTATCTCGGCCTGCTGCCCATGCTCCACTACACCTATTCGGCCATCAATCCGGTGGCGGTGAAGTCGCTCATGAAG
GCCGTCGGCCTGCCGGTGGGCGAGTTGCGCAAGCCGCTGCGCGGCCTTGAGGGCGAGGCGCTGGCCAAGGGCGTGCGCAT
CGTTCAGGAACTGGAGCTGGACCGCAAGTACGGCTTCAAGATCGCGCCGCTCTCCGCCGTCGCGGCCTGA

Upstream 100 bases:

>100_bases
TGCCCGTCCTCCACCAGCGCGGTGAAGGCGCCCCAATGGGCGAGATGGGGCTTGCGCTGGACGACCATGTGACGCCTCTT
CCGAAATCCGACGCCGGCCC

Downstream 100 bases:

>100_bases
GCGCCATGGATCTCGGCATCTCCGGCCGGCGGGCGCTGGTCAGCGGCGGCAGTCGCGGCATGGGCCGCGCCGTCGCCGAA
GTCCTCGCCCGTGACGGCGC

Product: dihydrodipicolinate synthase subfamily protein

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MTGRRHAIDRVQDAGQISNNYLKSSSTELNSRLRLLARRPISSRSAGGQQARRGTRPPMQKITGSFVAIVTPFNKDGSVD
FVAFRELLKFQEDNGTAAILIMGSTGETSMLSAEEKKKVIVETAKMKTAKMPLFYGCTGNNTETTIENVRFAKDNGADGA
ILAAPAYICAPEADIEGYFLDVADATDLPLGIYNNPPRVKSDLHWDNLLRIFKHPNYVIHKESTTRVGQVAQVLAARPDV
SVMCCDSPNLGLVVPTMSLGGHGTANMTGNIAPAELVAISRPWNGDEGAAAFKEAYLGLLPMLHYTYSAINPVAVKSLMK
AVGLPVGELRKPLRGLEGEALAKGVRIVQELELDRKYGFKIAPLSAVAA

Sequences:

>Translated_369_residues
MTGRRHAIDRVQDAGQISNNYLKSSSTELNSRLRLLARRPISSRSAGGQQARRGTRPPMQKITGSFVAIVTPFNKDGSVD
FVAFRELLKFQEDNGTAAILIMGSTGETSMLSAEEKKKVIVETAKMKTAKMPLFYGCTGNNTETTIENVRFAKDNGADGA
ILAAPAYICAPEADIEGYFLDVADATDLPLGIYNNPPRVKSDLHWDNLLRIFKHPNYVIHKESTTRVGQVAQVLAARPDV
SVMCCDSPNLGLVVPTMSLGGHGTANMTGNIAPAELVAISRPWNGDEGAAAFKEAYLGLLPMLHYTYSAINPVAVKSLMK
AVGLPVGELRKPLRGLEGEALAKGVRIVQELELDRKYGFKIAPLSAVAA
>Mature_368_residues
TGRRHAIDRVQDAGQISNNYLKSSSTELNSRLRLLARRPISSRSAGGQQARRGTRPPMQKITGSFVAIVTPFNKDGSVDF
VAFRELLKFQEDNGTAAILIMGSTGETSMLSAEEKKKVIVETAKMKTAKMPLFYGCTGNNTETTIENVRFAKDNGADGAI
LAAPAYICAPEADIEGYFLDVADATDLPLGIYNNPPRVKSDLHWDNLLRIFKHPNYVIHKESTTRVGQVAQVLAARPDVS
VMCCDSPNLGLVVPTMSLGGHGTANMTGNIAPAELVAISRPWNGDEGAAAFKEAYLGLLPMLHYTYSAINPVAVKSLMKA
VGLPVGELRKPLRGLEGEALAKGVRIVQELELDRKYGFKIAPLSAVAA

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=288, Percent_Identity=25, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1788823, Length=279, Percent_Identity=30.1075268817204, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI87082415, Length=276, Percent_Identity=28.2608695652174, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786463, Length=282, Percent_Identity=28.7234042553192, Blast_Score=95, Evalue=7e-21,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 39827; Mature: 39696

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGRRHAIDRVQDAGQISNNYLKSSSTELNSRLRLLARRPISSRSAGGQQARRGTRPPMQ
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCHH
KITGSFVAIVTPFNKDGSVDFVAFRELLKFQEDNGTAAILIMGSTGETSMLSAEEKKKVI
HHCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHCHHHHHHHH
VETAKMKTAKMPLFYGCTGNNTETTIENVRFAKDNGADGAILAAPAYICAPEADIEGYFL
HHHHHHHHHCCCEEEECCCCCCCHHHHHEEEECCCCCCCEEEECCCEEECCCCCCCEEEE
DVADATDLPLGIYNNPPRVKSDLHWDNLLRIFKHPNYVIHKESTTRVGQVAQVLAARPDV
EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCC
SVMCCDSPNLGLVVPTMSLGGHGTANMTGNIAPAELVAISRPWNGDEGAAAFKEAYLGLL
EEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHH
PMLHYTYSAINPVAVKSLMKAVGLPVGELRKPLRGLEGEALAKGVRIVQELELDRKYGFK
HHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCE
IAPLSAVAA
ECCHHHHCC
>Mature Secondary Structure 
TGRRHAIDRVQDAGQISNNYLKSSSTELNSRLRLLARRPISSRSAGGQQARRGTRPPMQ
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCHH
KITGSFVAIVTPFNKDGSVDFVAFRELLKFQEDNGTAAILIMGSTGETSMLSAEEKKKVI
HHCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHCHHHHHHHH
VETAKMKTAKMPLFYGCTGNNTETTIENVRFAKDNGADGAILAAPAYICAPEADIEGYFL
HHHHHHHHHCCCEEEECCCCCCCHHHHHEEEECCCCCCCEEEECCCEEECCCCCCCEEEE
DVADATDLPLGIYNNPPRVKSDLHWDNLLRIFKHPNYVIHKESTTRVGQVAQVLAARPDV
EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCC
SVMCCDSPNLGLVVPTMSLGGHGTANMTGNIAPAELVAISRPWNGDEGAAAFKEAYLGLL
EEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHH
PMLHYTYSAINPVAVKSLMKAVGLPVGELRKPLRGLEGEALAKGVRIVQELELDRKYGFK
HHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCE
IAPLSAVAA
ECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA