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The map label for this gene is mopB [C]

Identifier: 158424272

GI number: 158424272

Start: 2999263

End: 3001518

Strand: Reverse

Name: mopB [C]

Synonym: AZC_2648

Alternate gene names: 158424272

Gene position: 3001518-2999263 (Counterclockwise)

Preceding gene: 158424281

Following gene: 158424270

Centisome position: 55.9

GC content: 68.75

Gene sequence:

>2256_bases
ATGGTCGTCCAGCGCAAGCCCCATCTCGCCCATTGGGGCGCCTTCACCGCGCTGGTGGAGGACGGGCAGCTGGTGGGGTG
CGAGCCCTTCGCCGCGGACCCTGCGCCCTCGCCTTTGCTGGGCAGTATCGTGCCCTCTGTCTATTCGGACCGGCGCATCC
AGAAGCCCATGGTGCGGGAGAGCTTCCTGAAGCACGGCGCCGCGGCGGGAGGGGAGGGCCGTGGGCGCGAGCCCATGGTG
GAGGTCTCCTGGGAGACCGCACTCGATCTCGCCGCCCGCGAGATAAGCCGGGTGGAGGTGGAGCATGGGCGCGGCGCGCT
GTTCGCCGGCTCCTATGGCTGGTCCTCCGCCGGACGGCTGCACCATGCGCGCTCGTTGGTGCGGCGCTTCTATTTTTCCG
GCGGCGGGGCCATCGATCAGGTGGGCAATTACAGCTGGGGCACGGCGCAATTCCTTTTGCCCCATATCATCGGCACCTAC
CAGCCGCTGACCGGCCGTGCCACCTCCTGGCCGAGCATCCTCAAGCACTGCCGGCTCTTTCTCGCCTTCGGCGGGCTGGC
GCTGAAGAACGGGCAGATGGCCTCGGGCGGCGCGGCCGAGCATACGCAGGAGCACTGGCTGCGCGAACTCGCGAAGGCCG
GCATCCCGGTCATCAATGTTTCGCCCACGCGCGGCGACTGCCCGGACTTCCTGAACGCGGAATGGGTGCCCATCCGTCCC
ACCACGGATGCGGCCTTTCTGCTGGCCCTACTATCGGAAGTCCTCCGCATCCAGGGTGCGGACCTCGCCTTCCTCGCCAC
CCACACGGTGGGCTTCGAGCCGCTCGCCGCTTACGTGCGCGGGGAGAGCGACGGTGTGCCGAAGACGCCGGAATGGGCGC
AGGACATCTGCGGCGTGCCAGCGGAGCGCATCCGGCAGATCGCGGCGCGCCTCGTGGGCGTCCGCAGCTACATCACCTGC
TCTTTCGCCGTGCAGCGGGCGGAAAATGGCGAGCAGCCCTATTGGCTCGCTATCGCGCTCGCCAGCGTGCTCGGGCAGGT
GGGCCTGCCCGGAGGCGGCTTCGGCTTTGGCCATGGCTCCATGAATGGCGTCGGCAACCCGAGGCCCGCGACGCCCGGCC
CGGAGATGGCGGTTGGCGCCAATCCTCTGAAGCGGGCCATTCCCGCGGCCCGCATCACCGAAATGCTGGAGGCCCCCGGC
ACGTCCTATCCCTTCAACGGACGCACCGAGACCTATCCGGATGTCCGGCTCATTCATTGGGCGGGCGGCAATCCCTTCCA
CCACCATCAGGATCTCAACCGCTTCTCCCGCGCGTGGCAGAAGCCCGAGACCATCATCGTCAATGAAATCTGGTGGACGC
CCACCGCCCGGCGCGCCGACATCGTGCTGCCGGTGACGACCACGCTGGAGCGCAACGACATCGGCGGTTCCTCCCGCGAC
CGCTATGTGATCGCCATGCATCAGGCGATCGCACCGCTTCATGCGGCCCGCTCGGATTTCGACATCTTCGCCGATCTTGC
CGAGCGGCTGGGGCACGGCGTGGCCTTCACGGGCGGCCTCGACGAGCAGGGCTGGATCGAGCGCATCTATGCCGACTGCG
CGGCGGCCAATGCGAAAGCGGGCATCACCTTTCCCGATTTCGAGACCTTCTGGCAGGACGGCAGCTTCGAACTGCCCCGG
CCGGCGCAGGATTTCGTGCTGTTCGCCGATTTCCGCGCCGATCCGCAGGCCCATCCGCTCGCGACGCCCTCGGGCCGGAT
CGAGCTTTACAGCTCCGCCATCGCCTCTTTCGCGCTCTCCGACTGTCCGCCCCATCCGGTCTGGCGGGCGCCGGGCGAGT
GGCTGGGGAGCGCGGGCGCCAAGCGCCATCCCTTGCATCTCGTAACGGTGCAGCCCTCGGACAGGCTGCACAGCCAGCTC
GATTTCGCGCCCTTGCCTCAGGGCAACAAGGTGGATGGGCGCGAAGCGCTCCTCATGCATCCGGACGACGCCGCTGCGCG
CGGCTGCGTGGCCGGGCGGACGGTGCGCGTGTTCAACGACCGGGGTGCGCTGCTGGCGGGTCTGGTGCTGGACGAAGGCG
TGCATCGCGGCGTCGTGGTGATGGCGACGGGCGCCTGGTTCGACCCCGATCCCTCAGCCCCCGACGCGCCGGAGCGGGCC
GGCACGGTCAATGTGCTGACGCGCGATGTGGGCACATCCAGCCTCACCCAAGGGCCGAACGCCATGAGCTGCCTCGTGGA
GGTGGCGGCGGTCTAG

Upstream 100 bases:

>100_bases
TTCAAATAATTGTTTGAAATCTGACCCGCATCCTGCACCCTGTCAATAGCGTGTCGCCGCCCTGTCATGGGCCGGCGTCG
GATTTCGGAAGAGGCGTCAC

Downstream 100 bases:

>100_bases
CGCGCCGGGCGGCCGTCAGTTCCGGAGAAATATTCCGGGTGTGACTGGCGCAACTGCTCGACGAAATCCAGCGAGCGGGA
GAGGTGGTCCCGAAGCGCCT

Product: MopB superfamily protein

Products: Biotin [C]

Alternate protein names: BDS reductase; BSO reductase [H]

Number of amino acids: Translated: 751; Mature: 751

Protein sequence:

>751_residues
MVVQRKPHLAHWGAFTALVEDGQLVGCEPFAADPAPSPLLGSIVPSVYSDRRIQKPMVRESFLKHGAAAGGEGRGREPMV
EVSWETALDLAAREISRVEVEHGRGALFAGSYGWSSAGRLHHARSLVRRFYFSGGGAIDQVGNYSWGTAQFLLPHIIGTY
QPLTGRATSWPSILKHCRLFLAFGGLALKNGQMASGGAAEHTQEHWLRELAKAGIPVINVSPTRGDCPDFLNAEWVPIRP
TTDAAFLLALLSEVLRIQGADLAFLATHTVGFEPLAAYVRGESDGVPKTPEWAQDICGVPAERIRQIAARLVGVRSYITC
SFAVQRAENGEQPYWLAIALASVLGQVGLPGGGFGFGHGSMNGVGNPRPATPGPEMAVGANPLKRAIPAARITEMLEAPG
TSYPFNGRTETYPDVRLIHWAGGNPFHHHQDLNRFSRAWQKPETIIVNEIWWTPTARRADIVLPVTTTLERNDIGGSSRD
RYVIAMHQAIAPLHAARSDFDIFADLAERLGHGVAFTGGLDEQGWIERIYADCAAANAKAGITFPDFETFWQDGSFELPR
PAQDFVLFADFRADPQAHPLATPSGRIELYSSAIASFALSDCPPHPVWRAPGEWLGSAGAKRHPLHLVTVQPSDRLHSQL
DFAPLPQGNKVDGREALLMHPDDAAARGCVAGRTVRVFNDRGALLAGLVLDEGVHRGVVVMATGAWFDPDPSAPDAPERA
GTVNVLTRDVGTSSLTQGPNAMSCLVEVAAV

Sequences:

>Translated_751_residues
MVVQRKPHLAHWGAFTALVEDGQLVGCEPFAADPAPSPLLGSIVPSVYSDRRIQKPMVRESFLKHGAAAGGEGRGREPMV
EVSWETALDLAAREISRVEVEHGRGALFAGSYGWSSAGRLHHARSLVRRFYFSGGGAIDQVGNYSWGTAQFLLPHIIGTY
QPLTGRATSWPSILKHCRLFLAFGGLALKNGQMASGGAAEHTQEHWLRELAKAGIPVINVSPTRGDCPDFLNAEWVPIRP
TTDAAFLLALLSEVLRIQGADLAFLATHTVGFEPLAAYVRGESDGVPKTPEWAQDICGVPAERIRQIAARLVGVRSYITC
SFAVQRAENGEQPYWLAIALASVLGQVGLPGGGFGFGHGSMNGVGNPRPATPGPEMAVGANPLKRAIPAARITEMLEAPG
TSYPFNGRTETYPDVRLIHWAGGNPFHHHQDLNRFSRAWQKPETIIVNEIWWTPTARRADIVLPVTTTLERNDIGGSSRD
RYVIAMHQAIAPLHAARSDFDIFADLAERLGHGVAFTGGLDEQGWIERIYADCAAANAKAGITFPDFETFWQDGSFELPR
PAQDFVLFADFRADPQAHPLATPSGRIELYSSAIASFALSDCPPHPVWRAPGEWLGSAGAKRHPLHLVTVQPSDRLHSQL
DFAPLPQGNKVDGREALLMHPDDAAARGCVAGRTVRVFNDRGALLAGLVLDEGVHRGVVVMATGAWFDPDPSAPDAPERA
GTVNVLTRDVGTSSLTQGPNAMSCLVEVAAV
>Mature_751_residues
MVVQRKPHLAHWGAFTALVEDGQLVGCEPFAADPAPSPLLGSIVPSVYSDRRIQKPMVRESFLKHGAAAGGEGRGREPMV
EVSWETALDLAAREISRVEVEHGRGALFAGSYGWSSAGRLHHARSLVRRFYFSGGGAIDQVGNYSWGTAQFLLPHIIGTY
QPLTGRATSWPSILKHCRLFLAFGGLALKNGQMASGGAAEHTQEHWLRELAKAGIPVINVSPTRGDCPDFLNAEWVPIRP
TTDAAFLLALLSEVLRIQGADLAFLATHTVGFEPLAAYVRGESDGVPKTPEWAQDICGVPAERIRQIAARLVGVRSYITC
SFAVQRAENGEQPYWLAIALASVLGQVGLPGGGFGFGHGSMNGVGNPRPATPGPEMAVGANPLKRAIPAARITEMLEAPG
TSYPFNGRTETYPDVRLIHWAGGNPFHHHQDLNRFSRAWQKPETIIVNEIWWTPTARRADIVLPVTTTLERNDIGGSSRD
RYVIAMHQAIAPLHAARSDFDIFADLAERLGHGVAFTGGLDEQGWIERIYADCAAANAKAGITFPDFETFWQDGSFELPR
PAQDFVLFADFRADPQAHPLATPSGRIELYSSAIASFALSDCPPHPVWRAPGEWLGSAGAKRHPLHLVTVQPSDRLHSQL
DFAPLPQGNKVDGREALLMHPDDAAARGCVAGRTVRVFNDRGALLAGLVLDEGVHRGVVVMATGAWFDPDPSAPDAPERA
GTVNVLTRDVGTSSLTQGPNAMSCLVEVAAV

Specific function: This enzyme may serve as a scavenger, allowing the cell to utilize biotin sulfoxide as a biotin source. It reduces a spontaneous oxidation product of biotin, D-biotin D-sulfoxide (BSO or BDS), back to biotin [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081994, Length=757, Percent_Identity=39.7622192866579, Blast_Score=552, Evalue=1e-158,
Organism=Escherichia coli, GI145693196, Length=744, Percent_Identity=39.9193548387097, Blast_Score=516, Evalue=1e-147,
Organism=Escherichia coli, GI1787231, Length=764, Percent_Identity=38.2198952879581, Blast_Score=479, Evalue=1e-136,
Organism=Escherichia coli, GI87081797, Length=741, Percent_Identity=29.8245614035088, Blast_Score=258, Evalue=8e-70,
Organism=Escherichia coli, GI1787870, Length=716, Percent_Identity=28.7709497206704, Blast_Score=224, Evalue=2e-59,
Organism=Escherichia coli, GI171474008, Length=741, Percent_Identity=28.7449392712551, Blast_Score=219, Evalue=7e-58,
Organism=Escherichia coli, GI3868721, Length=538, Percent_Identity=22.4907063197026, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.7.2.3 [C]

Molecular weight: Translated: 80962; Mature: 80962

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00047 HISTONE_H4 ; PS00490 MOLYBDOPTERIN_PROK_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVQRKPHLAHWGAFTALVEDGQLVGCEPFAADPAPSPLLGSIVPSVYSDRRIQKPMVRE
CCCCCCCCCHHHHHHHHHCCCCCEECCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
SFLKHGAAAGGEGRGREPMVEVSWETALDLAAREISRVEVEHGRGALFAGSYGWSSAGRL
HHHHHCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHH
HHARSLVRRFYFSGGGAIDQVGNYSWGTAQFLLPHIIGTYQPLTGRATSWPSILKHCRLF
HHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
LAFGGLALKNGQMASGGAAEHTQEHWLRELAKAGIPVINVSPTRGDCPDFLNAEWVPIRP
HHHCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHCCCCEEECCC
TTDAAFLLALLSEVLRIQGADLAFLATHTVGFEPLAAYVRGESDGVPKTPEWAQDICGVP
CCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCHHHHHHHCCC
AERIRQIAARLVGVRSYITCSFAVQRAENGEQPYWLAIALASVLGQVGLPGGGFGFGHGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
MNGVGNPRPATPGPEMAVGANPLKRAIPAARITEMLEAPGTSYPFNGRTETYPDVRLIHW
CCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEE
AGGNPFHHHQDLNRFSRAWQKPETIIVNEIWWTPTARRADIVLPVTTTLERNDIGGSSRD
CCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEEEEEECEEECCCCCCCCCC
RYVIAMHQAIAPLHAARSDFDIFADLAERLGHGVAFTGGLDEQGWIERIYADCAAANAKA
CEEEEEHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCCC
GITFPDFETFWQDGSFELPRPAQDFVLFADFRADPQAHPLATPSGRIELYSSAIASFALS
CCCCCCHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
DCPPHPVWRAPGEWLGSAGAKRHPLHLVTVQPSDRLHSQLDFAPLPQGNKVDGREALLMH
CCCCCCCCCCCHHHHHCCCCCCCCEEEEEECCCHHHHHHCCCCCCCCCCCCCCCCEEEEC
PDDAAARGCVAGRTVRVFNDRGALLAGLVLDEGVHRGVVVMATGAWFDPDPSAPDAPERA
CCHHHHCCCCCCCEEEEECCCCCEEEHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCC
GTVNVLTRDVGTSSLTQGPNAMSCLVEVAAV
CEEEEEEECCCCHHHCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MVVQRKPHLAHWGAFTALVEDGQLVGCEPFAADPAPSPLLGSIVPSVYSDRRIQKPMVRE
CCCCCCCCCHHHHHHHHHCCCCCEECCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
SFLKHGAAAGGEGRGREPMVEVSWETALDLAAREISRVEVEHGRGALFAGSYGWSSAGRL
HHHHHCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHH
HHARSLVRRFYFSGGGAIDQVGNYSWGTAQFLLPHIIGTYQPLTGRATSWPSILKHCRLF
HHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
LAFGGLALKNGQMASGGAAEHTQEHWLRELAKAGIPVINVSPTRGDCPDFLNAEWVPIRP
HHHCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHCCCCEEECCC
TTDAAFLLALLSEVLRIQGADLAFLATHTVGFEPLAAYVRGESDGVPKTPEWAQDICGVP
CCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCHHHHHHHCCC
AERIRQIAARLVGVRSYITCSFAVQRAENGEQPYWLAIALASVLGQVGLPGGGFGFGHGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
MNGVGNPRPATPGPEMAVGANPLKRAIPAARITEMLEAPGTSYPFNGRTETYPDVRLIHW
CCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEE
AGGNPFHHHQDLNRFSRAWQKPETIIVNEIWWTPTARRADIVLPVTTTLERNDIGGSSRD
CCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEEEEEECEEECCCCCCCCCC
RYVIAMHQAIAPLHAARSDFDIFADLAERLGHGVAFTGGLDEQGWIERIYADCAAANAKA
CEEEEEHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCCC
GITFPDFETFWQDGSFELPRPAQDFVLFADFRADPQAHPLATPSGRIELYSSAIASFALS
CCCCCCHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
DCPPHPVWRAPGEWLGSAGAKRHPLHLVTVQPSDRLHSQLDFAPLPQGNKVDGREALLMH
CCCCCCCCCCCHHHHHCCCCCCCCEEEEEECCCHHHHHHCCCCCCCCCCCCCCCCEEEEC
PDDAAARGCVAGRTVRVFNDRGALLAGLVLDEGVHRGVVVMATGAWFDPDPSAPDAPERA
CCHHHHCCCCCCCEEEEECCCCCEEEHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCC
GTVNVLTRDVGTSSLTQGPNAMSCLVEVAAV
CEEEEEEECCCCHHHCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds) [C]

Specific reaction: Reduces A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds), Back To Biotin. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7733660 [H]