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The map label for this gene is thyX [H]

Identifier: 158424201

GI number: 158424201

Start: 2903373

End: 2904314

Strand: Direct

Name: thyX [H]

Synonym: AZC_2577

Alternate gene names: 158424201

Gene position: 2903373-2904314 (Clockwise)

Preceding gene: 158424199

Following gene: 158424206

Centisome position: 54.07

GC content: 65.5

Gene sequence:

>942_bases
ATGAGCATCACCGGCCAGCAACTCGAGGACATCCGCCAGGCGCGCGCGACGACCACGGCCACCCTGCGGCCGACCGTGCC
GGCGCTGGAGGAGGTGCTCTATGAGCCCATCCCGCTGCTCGACCACGGCTTCATCCGGGTGATCGACTATATGGGCGACG
ACAATGCCGTGGTGCAGGCCGCCCGCGTCTCCTACGGACGCGGCACCAAGAAGGTGAGCGAGGATCGCGGCCTCATCATG
TATCTGATGCGGCACTGGCACACGACGCCGTTCGAGATGGCCGAGATCAAGTTCCATGTGAAGCTGCCCATCTTCGTGGC
GCGCCAGTGGATCCGCCATCGCACCGCCAGCGTGAACGAATATTCCGCCCGCTATTCCATCCTCGACAAGGAATTCTATC
TGCCGGCGCCGGAGCAGCTCGCCGCCCAATCGAGCGCGAACCGGCAGGGGCGCGGCGACGTGCTGGAGGGTGAGGAAGCC
CAGCGGGTGCTCGACCTGCTGCGCGGCGATGCCGAGCGCACCTATGCCGATTATGCCTGGATGCTGAACGAGGGCACGGA
CGAGCAGGCCGCCGATCCCGACCGCTCGGGCCTGGCGCGTGAACTCGCCCGGATGAACCTGACGCTGAACACCTATACTC
AGTGGTATTGGAAGACCAATCTCCACAATCTCATGCACTTCCTGCGCCTGCGGGCCGATCCGCATGCGCAGTATGAGATC
CGCGTCTATGCGGAGAAGATGCTCGACATCATGAAGCGCTGGGTGCCGATCACCACGGAAGCCTTCATCGAGCACCGCAT
GGAATCGGCGAGCCTCTCGCGCACGGCGCTGGCGGCGGTGAAGCGCATGATCGCTGGTGAACAGGTGACAGCGGCCACCA
GCGGCCTCTCCGCCCGCGAGTGGCGGGAACTCGCCGCCACCCTCGGCCTCCCCGAGGCCTGA

Upstream 100 bases:

>100_bases
GGCGTGAGAGCCTTCCGGCCCGGATGCCTCATGCCGCAGCCAACGGGCTTGCCGAGGAACGGCCGCCGCCTTAAGCGGGG
GGACCATCACGAGGACCGCC

Downstream 100 bases:

>100_bases
TCGGATGAGCGCTCGTCGCCCCTCCCCGCCTCAATCGAGGCCGGGCGGGCGGCGGAAGCCGTAGAGCGCTTCGAGCGCGG
CGGCGAAGGCGATGGGCGTG

Product: FAD-dependent thymidylate synthase

Products: NA

Alternate protein names: TS; TSase [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSITGQQLEDIRQARATTTATLRPTVPALEEVLYEPIPLLDHGFIRVIDYMGDDNAVVQAARVSYGRGTKKVSEDRGLIM
YLMRHWHTTPFEMAEIKFHVKLPIFVARQWIRHRTASVNEYSARYSILDKEFYLPAPEQLAAQSSANRQGRGDVLEGEEA
QRVLDLLRGDAERTYADYAWMLNEGTDEQAADPDRSGLARELARMNLTLNTYTQWYWKTNLHNLMHFLRLRADPHAQYEI
RVYAEKMLDIMKRWVPITTEAFIEHRMESASLSRTALAAVKRMIAGEQVTAATSGLSAREWRELAATLGLPEA

Sequences:

>Translated_313_residues
MSITGQQLEDIRQARATTTATLRPTVPALEEVLYEPIPLLDHGFIRVIDYMGDDNAVVQAARVSYGRGTKKVSEDRGLIM
YLMRHWHTTPFEMAEIKFHVKLPIFVARQWIRHRTASVNEYSARYSILDKEFYLPAPEQLAAQSSANRQGRGDVLEGEEA
QRVLDLLRGDAERTYADYAWMLNEGTDEQAADPDRSGLARELARMNLTLNTYTQWYWKTNLHNLMHFLRLRADPHAQYEI
RVYAEKMLDIMKRWVPITTEAFIEHRMESASLSRTALAAVKRMIAGEQVTAATSGLSAREWRELAATLGLPEA
>Mature_312_residues
SITGQQLEDIRQARATTTATLRPTVPALEEVLYEPIPLLDHGFIRVIDYMGDDNAVVQAARVSYGRGTKKVSEDRGLIMY
LMRHWHTTPFEMAEIKFHVKLPIFVARQWIRHRTASVNEYSARYSILDKEFYLPAPEQLAAQSSANRQGRGDVLEGEEAQ
RVLDLLRGDAERTYADYAWMLNEGTDEQAADPDRSGLARELARMNLTLNTYTQWYWKTNLHNLMHFLRLRADPHAQYEIR
VYAEKMLDIMKRWVPITTEAFIEHRMESASLSRTALAAVKRMIAGEQVTAATSGLSAREWRELAATLGLPEA

Specific function: Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate [H]

COG id: COG1351

COG function: function code F; Predicted alternative thymidylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thyX (flavin-dependent thymidylate synthase) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003669 [H]

Pfam domain/function: PF02511 Thy1 [H]

EC number: =2.1.1.148 [H]

Molecular weight: Translated: 35812; Mature: 35681

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSITGQQLEDIRQARATTTATLRPTVPALEEVLYEPIPLLDHGFIRVIDYMGDDNAVVQA
CCCCHHHHHHHHHHHHHCCEECCCCHHHHHHHHHCCCCCHHCCHHHHHHHCCCCHHHHHH
ARVSYGRGTKKVSEDRGLIMYLMRHWHTTPFEMAEIKFHVKLPIFVARQWIRHRTASVNE
HHHHCCCCCCHHHCCCCHHHHHHHHHCCCCCEEEEEEEEEECHHHHHHHHHHHHHCCCHH
YSARYSILDKEFYLPAPEQLAAQSSANRQGRGDVLEGEEAQRVLDLLRGDAERTYADYAW
HHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHH
MLNEGTDEQAADPDRSGLARELARMNLTLNTYTQWYWKTNLHNLMHFLRLRADPHAQYEI
EECCCCCCCCCCCCHHHHHHHHHHHCCEEEHHHHHEEHHHHHHHHHHHHHCCCCCCCEEE
RVYAEKMLDIMKRWVPITTEAFIEHRMESASLSRTALAAVKRMIAGEQVTAATSGLSARE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHH
WRELAATLGLPEA
HHHHHHHCCCCCC
>Mature Secondary Structure 
SITGQQLEDIRQARATTTATLRPTVPALEEVLYEPIPLLDHGFIRVIDYMGDDNAVVQA
CCCHHHHHHHHHHHHHCCEECCCCHHHHHHHHHCCCCCHHCCHHHHHHHCCCCHHHHHH
ARVSYGRGTKKVSEDRGLIMYLMRHWHTTPFEMAEIKFHVKLPIFVARQWIRHRTASVNE
HHHHCCCCCCHHHCCCCHHHHHHHHHCCCCCEEEEEEEEEECHHHHHHHHHHHHHCCCHH
YSARYSILDKEFYLPAPEQLAAQSSANRQGRGDVLEGEEAQRVLDLLRGDAERTYADYAW
HHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHH
MLNEGTDEQAADPDRSGLARELARMNLTLNTYTQWYWKTNLHNLMHFLRLRADPHAQYEI
EECCCCCCCCCCCCHHHHHHHHHHHCCEEEHHHHHEEHHHHHHHHHHHHHCCCCCCCEEE
RVYAEKMLDIMKRWVPITTEAFIEHRMESASLSRTALAAVKRMIAGEQVTAATSGLSARE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHH
WRELAATLGLPEA
HHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA