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The map label for this gene is yeaP [H]

Identifier: 158424136

GI number: 158424136

Start: 2847262

End: 2848251

Strand: Direct

Name: yeaP [H]

Synonym: AZC_2512

Alternate gene names: 158424136

Gene position: 2847262-2848251 (Clockwise)

Preceding gene: 158424131

Following gene: 158424137

Centisome position: 53.02

GC content: 67.78

Gene sequence:

>990_bases
GTGAGCTCGGCGCGCTCACTGGAGGAGCTGACGCGGCCGCTGCTGGAGCTTCTGGAGCTGATTACCGGCCTTGAGAGCAC
CTTCCTGACGCGCATCGATTTCGCAGCGGGCATCCAGAACGTCCTGTTTTCCCGCAACAGCAGCACCTTGCACTTGCCGG
AGACGCTCTCGGTTCCCTGGGGCGACACGCTGTGCAAGCGCGCGCTGGCCGAGCAATGCCCCTATGCCGACGACGTCTCG
ACCCGCTGGGGTGATTCTGAGGCGGCCCGCGTCCTCGGCATCGAGACCTTCACGAGCACACCCGTCTATCTCGAGGGCGG
CTCGCTCTATGGGACGCTGTGCGCGGCGAGTTGCGATCGCAAGCCGATCTCGTCCGACGGCCAGCACGTGCTGCGCCTGT
TCTCGGCGCTCATCGCACAACAGATCCAGCAGGACCAGCTGATGCAGGAGCTGCGCCGCGCCAATGCGCAGCTCGCGGCC
TATTCGTTTACGGACGCGCTCACCGGCCTGCCCAACCGCCGTTTCATCCTCGACGAGCTCCAGCGCATGATGGCGCAGGC
CGCGCGCAGCGGGCAGAACCTGATCGTCGCCTTCATCGACCTCGACGGCTTCAAGGCCATCAACGATGCCCATGGCCATG
ACGCCGGAGATGCCTTCCTGATCGAGGTGGGCCGCCGCCTGTCGCTGGGTCTTCGGGCCGGCGACGTGCTGGGACGGCTC
GGCGGCGACGAATTCGTCATGGTGGGCTTCACCGCGCCGGGCGAGCCCGGCCGCGCGCCGGCCGATGCCACGCGCCAGCG
CCTCACTGCTCTGATCGAGGGCCATTACGAACTCGGCCGCTGGCGCATCGACTATGAGGGCGCGAGCATCGGCGTGATCG
AAGCCGAACCCGGCGAGAGCGCGCCCGAGGAGATTCTGCGCCGGGCCGACGCCCTCATGTACGAGACCAAGAAGGCGCGC
CGGGCCACCCGCCGGTCAGCGACGGGATAG

Upstream 100 bases:

>100_bases
CCCATCCGACGCAACGGAGGGCACGCCGCAGGGAGCCGGCCTTACCCCCATGAACGAGCACGTTTCCAAGGATCTGGTCC
TCGCCCGCCTCTCCGAGACG

Downstream 100 bases:

>100_bases
GCGCTTTTCCCATCTCCGTGTCATTTCCTCCGCCTGCGCACAGCGAAACGGAACGATCGCCGGCACCAGAAGGCTGCCAT
GTGCGCGGGCCGAGGCGACT

Product: hypothetical protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MSSARSLEELTRPLLELLELITGLESTFLTRIDFAAGIQNVLFSRNSSTLHLPETLSVPWGDTLCKRALAEQCPYADDVS
TRWGDSEAARVLGIETFTSTPVYLEGGSLYGTLCAASCDRKPISSDGQHVLRLFSALIAQQIQQDQLMQELRRANAQLAA
YSFTDALTGLPNRRFILDELQRMMAQAARSGQNLIVAFIDLDGFKAINDAHGHDAGDAFLIEVGRRLSLGLRAGDVLGRL
GGDEFVMVGFTAPGEPGRAPADATRQRLTALIEGHYELGRWRIDYEGASIGVIEAEPGESAPEEILRRADALMYETKKAR
RATRRSATG

Sequences:

>Translated_329_residues
MSSARSLEELTRPLLELLELITGLESTFLTRIDFAAGIQNVLFSRNSSTLHLPETLSVPWGDTLCKRALAEQCPYADDVS
TRWGDSEAARVLGIETFTSTPVYLEGGSLYGTLCAASCDRKPISSDGQHVLRLFSALIAQQIQQDQLMQELRRANAQLAA
YSFTDALTGLPNRRFILDELQRMMAQAARSGQNLIVAFIDLDGFKAINDAHGHDAGDAFLIEVGRRLSLGLRAGDVLGRL
GGDEFVMVGFTAPGEPGRAPADATRQRLTALIEGHYELGRWRIDYEGASIGVIEAEPGESAPEEILRRADALMYETKKAR
RATRRSATG
>Mature_328_residues
SSARSLEELTRPLLELLELITGLESTFLTRIDFAAGIQNVLFSRNSSTLHLPETLSVPWGDTLCKRALAEQCPYADDVST
RWGDSEAARVLGIETFTSTPVYLEGGSLYGTLCAASCDRKPISSDGQHVLRLFSALIAQQIQQDQLMQELRRANAQLAAY
SFTDALTGLPNRRFILDELQRMMAQAARSGQNLIVAFIDLDGFKAINDAHGHDAGDAFLIEVGRRLSLGLRAGDVLGRLG
GDEFVMVGFTAPGEPGRAPADATRQRLTALIEGHYELGRWRIDYEGASIGVIEAEPGESAPEEILRRADALMYETKKARR
ATRRSATG

Specific function: Catalyzes the condensation of two GTP molecules to the cyclic dinucleotide di-GMP (c-di-GMP), which acts as a secondary messenger (Probable). Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: COG2203

COG function: function code T; FOG: GAF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87081977, Length=323, Percent_Identity=46.749226006192, Blast_Score=315, Evalue=3e-87,
Organism=Escherichia coli, GI1786584, Length=181, Percent_Identity=32.5966850828729, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788381, Length=264, Percent_Identity=28.7878787878788, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787541, Length=174, Percent_Identity=31.0344827586207, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI145693134, Length=104, Percent_Identity=40.3846153846154, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI87081881, Length=189, Percent_Identity=32.8042328042328, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787262, Length=158, Percent_Identity=30.379746835443, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788956, Length=173, Percent_Identity=35.2601156069364, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87081974, Length=103, Percent_Identity=33.9805825242718, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082007, Length=168, Percent_Identity=33.9285714285714, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787816, Length=170, Percent_Identity=30.5882352941176, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR003018 [H]

Pfam domain/function: PF01590 GAF; PF00990 GGDEF [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 35972; Mature: 35841

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSARSLEELTRPLLELLELITGLESTFLTRIDFAAGIQNVLFSRNSSTLHLPETLSVPW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCC
GDTLCKRALAEQCPYADDVSTRWGDSEAARVLGIETFTSTPVYLEGGSLYGTLCAASCDR
CHHHHHHHHHHHCCCCCCCCCCCCCCHHHHEEEEEECCCCCEEEECCCEEEHHHHHCCCC
KPISSDGQHVLRLFSALIAQQIQQDQLMQELRRANAQLAAYSFTDALTGLPNRRFILDEL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHCCCCCHHHHHHH
QRMMAQAARSGQNLIVAFIDLDGFKAINDAHGHDAGDAFLIEVGRRLSLGLRAGDVLGRL
HHHHHHHHHCCCCEEEEEEECCCCHHHCCCCCCCCCCHHHHHHCCHHHCCCCHHHHHHHC
GGDEFVMVGFTAPGEPGRAPADATRQRLTALIEGHYELGRWRIDYEGASIGVIEAEPGES
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHCCEEEEECCCEEEEEECCCCCC
APEEILRRADALMYETKKARRATRRSATG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSARSLEELTRPLLELLELITGLESTFLTRIDFAAGIQNVLFSRNSSTLHLPETLSVPW
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCC
GDTLCKRALAEQCPYADDVSTRWGDSEAARVLGIETFTSTPVYLEGGSLYGTLCAASCDR
CHHHHHHHHHHHCCCCCCCCCCCCCCHHHHEEEEEECCCCCEEEECCCEEEHHHHHCCCC
KPISSDGQHVLRLFSALIAQQIQQDQLMQELRRANAQLAAYSFTDALTGLPNRRFILDEL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHCCCCCHHHHHHH
QRMMAQAARSGQNLIVAFIDLDGFKAINDAHGHDAGDAFLIEVGRRLSLGLRAGDVLGRL
HHHHHHHHHCCCCEEEEEEECCCCHHHCCCCCCCCCCHHHHHHCCHHHCCCCHHHHHHHC
GGDEFVMVGFTAPGEPGRAPADATRQRLTALIEGHYELGRWRIDYEGASIGVIEAEPGES
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHCCEEEEECCCEEEEEECCCCCC
APEEILRRADALMYETKKARRATRRSATG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]