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The map label for this gene is lysR [H]

Identifier: 158424122

GI number: 158424122

Start: 2832191

End: 2833087

Strand: Direct

Name: lysR [H]

Synonym: AZC_2498

Alternate gene names: 158424122

Gene position: 2832191-2833087 (Clockwise)

Preceding gene: 158424121

Following gene: 158424123

Centisome position: 52.74

GC content: 69.01

Gene sequence:

>897_bases
ATGCGCGCCATGCTGCATCACGATCTGCAATCGCTCCGCCTGTTCGTCGCCGTCTGCGAGACGCGCAGCCTCTCCAAGGC
GGCGGAGCGGATGAATCTGGCGCTCTCCGCCGCCAGCCGCCGCCTGCGCCTGCTGGAAGAGGAGGCGGGCATGCCTCTGG
TGCGCCGCCTGCCCCATGGGGTCGAGCCCACCATGGCCGGGCAGACCGCCCTCTCCTATGCCCAGTCCGTGCTCATGCTG
GCGGATCGCTATGTGGCGGGTCTCGCCGACCACCGCTCCGGTGCGCGCGGACGGGTGCGGGTTTCGGCCTCCAGTTCCGC
GCTGGTGGAGCGCCTCGCCACCGACCTTGCGGACTTCGCCAAGCGCCATCCCGACATCCGTATCGACCTGGAAGAACAGC
CCACGGCCGACACCATCGCCGCCGTGACCCGCAAGCAGGCGGACCTCGGCGTCATCGTGCGCGGACAGGCGGTGGAGGGG
CTGACGCTTCTTCCCTATTCCACTGACCGCCTGTCCGTTGTGGTGCGCAGCGATCATCCGTTGGCGGATCGGGCGGCCGT
CGCCTTCTCGGACCTGCTCGACGAGGATTTCGTGGCGCTCGAAGCCGGCACCGCCGTCAACCGGCTGGTGATGGAGCGGG
CGCGGGAGTTGGGGCGGTTCCTCAAGGTACGGGTGCAGGTGCGCAGCTTCGAAGTAATGTGCCAGATGGTGCACCACGGC
CTCGGCATCGGCATCCTGCCCGAGGCGGCGCTACGCCCGCTCGCCACGGCGCTGGGCCTCACCCTCGTCCGACTGGAAGA
GACCTGGGCGGCGCGCGAGATCGCCATCTGCCTGAGGGAAAACGAGGAATTGCCGAGCGCCACGCGCCGACTGCTGGACG
AGTTGCTGACGAGCTAG

Upstream 100 bases:

>100_bases
CGCGCATTTCTCGGAGATATGGGCGGATCTGGAGATCCCCAAGGCGGCGTGAGTTCGGCCGCGCGCTTTCTCCTCGCGCC
GCGCGGAGGGCCGCGCCAAA

Downstream 100 bases:

>100_bases
CGCCTGCGCATTTCGCGAAATCTGAATGCTTTCTTTTCTAATTCCGCGAAGCACGCACCTGAGCTTACCCTGCCTGTGCT
GGAGAAACAGGCATGACTGC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MRAMLHHDLQSLRLFVAVCETRSLSKAAERMNLALSAASRRLRLLEEEAGMPLVRRLPHGVEPTMAGQTALSYAQSVLML
ADRYVAGLADHRSGARGRVRVSASSSALVERLATDLADFAKRHPDIRIDLEEQPTADTIAAVTRKQADLGVIVRGQAVEG
LTLLPYSTDRLSVVVRSDHPLADRAAVAFSDLLDEDFVALEAGTAVNRLVMERARELGRFLKVRVQVRSFEVMCQMVHHG
LGIGILPEAALRPLATALGLTLVRLEETWAAREIAICLRENEELPSATRRLLDELLTS

Sequences:

>Translated_298_residues
MRAMLHHDLQSLRLFVAVCETRSLSKAAERMNLALSAASRRLRLLEEEAGMPLVRRLPHGVEPTMAGQTALSYAQSVLML
ADRYVAGLADHRSGARGRVRVSASSSALVERLATDLADFAKRHPDIRIDLEEQPTADTIAAVTRKQADLGVIVRGQAVEG
LTLLPYSTDRLSVVVRSDHPLADRAAVAFSDLLDEDFVALEAGTAVNRLVMERARELGRFLKVRVQVRSFEVMCQMVHHG
LGIGILPEAALRPLATALGLTLVRLEETWAAREIAICLRENEELPSATRRLLDELLTS
>Mature_298_residues
MRAMLHHDLQSLRLFVAVCETRSLSKAAERMNLALSAASRRLRLLEEEAGMPLVRRLPHGVEPTMAGQTALSYAQSVLML
ADRYVAGLADHRSGARGRVRVSASSSALVERLATDLADFAKRHPDIRIDLEEQPTADTIAAVTRKQADLGVIVRGQAVEG
LTLLPYSTDRLSVVVRSDHPLADRAAVAFSDLLDEDFVALEAGTAVNRLVMERARELGRFLKVRVQVRSFEVMCQMVHHG
LGIGILPEAALRPLATALGLTLVRLEETWAAREIAICLRENEELPSATRRLLDELLTS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=300, Percent_Identity=25.3333333333333, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787879, Length=294, Percent_Identity=26.530612244898, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI157672245, Length=229, Percent_Identity=27.5109170305677, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788748, Length=289, Percent_Identity=24.5674740484429, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787530, Length=259, Percent_Identity=25.4826254826255, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788297, Length=269, Percent_Identity=28.996282527881, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787589, Length=253, Percent_Identity=28.8537549407115, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI2367136, Length=271, Percent_Identity=23.9852398523985, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790208, Length=247, Percent_Identity=25.5060728744939, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787806, Length=265, Percent_Identity=24.5283018867925, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786713, Length=252, Percent_Identity=27.3809523809524, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790399, Length=284, Percent_Identity=22.887323943662, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788887, Length=286, Percent_Identity=26.2237762237762, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI87081904, Length=202, Percent_Identity=30.1980198019802, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32766; Mature: 32766

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAMLHHDLQSLRLFVAVCETRSLSKAAERMNLALSAASRRLRLLEEEAGMPLVRRLPHG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
VEPTMAGQTALSYAQSVLMLADRYVAGLADHRSGARGRVRVSASSSALVERLATDLADFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHH
KRHPDIRIDLEEQPTADTIAAVTRKQADLGVIVRGQAVEGLTLLPYSTDRLSVVVRSDHP
HHCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCCCEEECCCCCCCEEEEEECCCC
LADRAAVAFSDLLDEDFVALEAGTAVNRLVMERARELGRFLKVRVQVRSFEVMCQMVHHG
CHHHHHHHHHHHHCHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LGIGILPEAALRPLATALGLTLVRLEETWAAREIAICLRENEELPSATRRLLDELLTS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRAMLHHDLQSLRLFVAVCETRSLSKAAERMNLALSAASRRLRLLEEEAGMPLVRRLPHG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
VEPTMAGQTALSYAQSVLMLADRYVAGLADHRSGARGRVRVSASSSALVERLATDLADFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHH
KRHPDIRIDLEEQPTADTIAAVTRKQADLGVIVRGQAVEGLTLLPYSTDRLSVVVRSDHP
HHCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCCCEEECCCCCCCEEEEEECCCC
LADRAAVAFSDLLDEDFVALEAGTAVNRLVMERARELGRFLKVRVQVRSFEVMCQMVHHG
CHHHHHHHHHHHHCHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LGIGILPEAALRPLATALGLTLVRLEETWAAREIAICLRENEELPSATRRLLDELLTS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]