Click here to switch to the map view.

The map label for this gene is rutD

Identifier: 158424120

GI number: 158424120

Start: 2830554

End: 2831351

Strand: Direct

Name: rutD

Synonym: AZC_2496

Alternate gene names: 158424120

Gene position: 2830554-2831351 (Clockwise)

Preceding gene: 158424119

Following gene: 158424121

Centisome position: 52.71

GC content: 69.17

Gene sequence:

>798_bases
ATGCCCTATGCGCACGGCGGCGACGCCGACCTCTATTATGAAATCCACGGCGCGGGGACGCCCATCCTGCTCTCCGCCGG
CATGGGCGGGGGCGCCGGCTTCTGGCGCCCGCAGATCGAGGCCCTCGCGGCCCGGCATCAGGTGATCCTCTATGATCATG
CCGGCACCGGGCGCAGTGGGCGGGACATCGGCCCGCGCAGCATCACGGAAATGGCGCGTGACATGGCGCGGGTGCTCGAT
GCGGCGGGCGTGGAGGATGCCCATGTGGCGGGCCACGCCATCGGCGGCATCATCGGCATGGAACTGGCGCTTGCGGCGCC
CGAGCGGGTGCGCAGCCTCACCATCGTCAACGGCTGGGCGCGGGCGGACGGCTTCCTGCGGCGCTGCTTCGAGGTGCGCA
AGCGCATCCTCCTCGCCTCCGGCCCGGAAGCCTATGTGCGCGCGCAGCCGCTCTTCCTCTATCCGCCCCGCTGGATCGCC
GAGAACATCGCCGTTCTGGAGGAGGAAGAGGCGCAAATGGTGGCGCACTTTCCCGGGACGCAGACCATGCTGAACCGCAT
CGAGACCTTCCTCGCCTTCGACGGGCGCGAGCGCCTCGCGGACATCCGCGTGCCGACGCTGCTCGCTGCGGCGAAGGACG
ATGCGCTCGTGCCCTCCTATCTCTCGACCCTGCTGGCGGAAGGCATTCCGGACGCGCGCATCGCCGAGGTGGACTGGGGC
GCGCACGCGTTCAGCGCGGTGACGCCGGACGTTTTCAACGAAATGCTGCTCGGCTTCTGCGGAGAGATCGACCAATGA

Upstream 100 bases:

>100_bases
TCATGGGTGTCGCGCTGGCCATGTACGGCGTCATCGACCTGATCGAACGGCGCCTGCGCGCCTGACCATCCCAAAATCCC
GTTAAAAGCGAAGACGTTCC

Downstream 100 bases:

>100_bases
GCGAAGGATCAGGCGGGCGCCGGATCGTCCTGCGGGCTGATGATGTGAGCGTCGTCTTTCCGGGCACGAACGGCCCGGTG
GAAGCCATCCGCAAGGTGGA

Product: hydrolase

Products: NA

Alternate protein names: Aminohydrolase

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MPYAHGGDADLYYEIHGAGTPILLSAGMGGGAGFWRPQIEALAARHQVILYDHAGTGRSGRDIGPRSITEMARDMARVLD
AAGVEDAHVAGHAIGGIIGMELALAAPERVRSLTIVNGWARADGFLRRCFEVRKRILLASGPEAYVRAQPLFLYPPRWIA
ENIAVLEEEEAQMVAHFPGTQTMLNRIETFLAFDGRERLADIRVPTLLAAAKDDALVPSYLSTLLAEGIPDARIAEVDWG
AHAFSAVTPDVFNEMLLGFCGEIDQ

Sequences:

>Translated_265_residues
MPYAHGGDADLYYEIHGAGTPILLSAGMGGGAGFWRPQIEALAARHQVILYDHAGTGRSGRDIGPRSITEMARDMARVLD
AAGVEDAHVAGHAIGGIIGMELALAAPERVRSLTIVNGWARADGFLRRCFEVRKRILLASGPEAYVRAQPLFLYPPRWIA
ENIAVLEEEEAQMVAHFPGTQTMLNRIETFLAFDGRERLADIRVPTLLAAAKDDALVPSYLSTLLAEGIPDARIAEVDWG
AHAFSAVTPDVFNEMLLGFCGEIDQ
>Mature_264_residues
PYAHGGDADLYYEIHGAGTPILLSAGMGGGAGFWRPQIEALAARHQVILYDHAGTGRSGRDIGPRSITEMARDMARVLDA
AGVEDAHVAGHAIGGIIGMELALAAPERVRSLTIVNGWARADGFLRRCFEVRKRILLASGPEAYVRAQPLFLYPPRWIAE
NIAVLEEEEAQMVAHFPGTQTMLNRIETFLAFDGRERLADIRVPTLLAAAKDDALVPSYLSTLLAEGIPDARIAEVDWGA
HAFSAVTPDVFNEMLLGFCGEIDQ

Specific function: May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Hydrolase RutD family

Homologues:

Organism=Escherichia coli, GI1787244, Length=233, Percent_Identity=39.9141630901288, Blast_Score=185, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUTD_AZOC5 (A8IAD8)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001525412.1
- ProteinModelPortal:   A8IAD8
- SMR:   A8IAD8
- GeneID:   5690322
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_2496
- HOGENOM:   HBG748003
- OMA:   YRREHAS
- BioCyc:   ACAU438753:AZC_2496-MONOMER
- HAMAP:   MF_00832
- InterPro:   IPR000073
- InterPro:   IPR019913
- PRINTS:   PR00111
- TIGRFAMs:   TIGR03611

Pfam domain/function: PF00561 Abhydrolase_1

EC number: NA

Molecular weight: Translated: 28703; Mature: 28572

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYAHGGDADLYYEIHGAGTPILLSAGMGGGAGFWRPQIEALAARHQVILYDHAGTGRSG
CCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCC
RDIGPRSITEMARDMARVLDAAGVEDAHVAGHAIGGIIGMELALAAPERVRSLTIVNGWA
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHEEEEECCHH
RADGFLRRCFEVRKRILLASGPEAYVRAQPLFLYPPRWIAENIAVLEEEEAQMVAHFPGT
HHHHHHHHHHHHHHHHHHCCCCCHHEEECCEEEECCHHHHHHHHHHCHHHHHHEEECCCH
QTMLNRIETFLAFDGRERLADIRVPTLLAAAKDDALVPSYLSTLLAEGIPDARIAEVDWG
HHHHHHHHHHHHCCCHHHHHHHCHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEECCC
AHAFSAVTPDVFNEMLLGFCGEIDQ
CHHHHHCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PYAHGGDADLYYEIHGAGTPILLSAGMGGGAGFWRPQIEALAARHQVILYDHAGTGRSG
CCCCCCCCEEEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCC
RDIGPRSITEMARDMARVLDAAGVEDAHVAGHAIGGIIGMELALAAPERVRSLTIVNGWA
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHEEEEECCHH
RADGFLRRCFEVRKRILLASGPEAYVRAQPLFLYPPRWIAENIAVLEEEEAQMVAHFPGT
HHHHHHHHHHHHHHHHHHCCCCCHHEEECCEEEECCHHHHHHHHHHCHHHHHHEEECCCH
QTMLNRIETFLAFDGRERLADIRVPTLLAAAKDDALVPSYLSTLLAEGIPDARIAEVDWG
HHHHHHHHHHHHCCCHHHHHHHCHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEECCC
AHAFSAVTPDVFNEMLLGFCGEIDQ
CHHHHHCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA