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The map label for this gene is deoA [C]

Identifier: 158424091

GI number: 158424091

Start: 2802843

End: 2804924

Strand: Reverse

Name: deoA [C]

Synonym: AZC_2467

Alternate gene names: 158424091

Gene position: 2804924-2802843 (Counterclockwise)

Preceding gene: 158424092

Following gene: 158424090

Centisome position: 52.24

GC content: 69.69

Gene sequence:

>2082_bases
GTGAGCGTCATGGGATCGGGACTCTTCTTCTTCGTGGTCGGGCCGAGCGGCTCGGGCAAGGACACCCTCATCGAGGGGGC
GAAGGCGGCTCTCGGTCCCACCGGACGTTACGTGTTTGCGCGCCGGGCCATCACCCGGCCGGCCGATGCGGGCGGCGAGG
CGCACGAGGCGCTGAGCGTTGACCAGTTTGACGCCGTGCTGGCGCAGGGCGGATTCCTGATCCATTGGGAGGCCCATGGG
CTCAAATACGGCCTGCGCGCCACACTGCTCGACGACATGGCCGCCGGGCGTCACGTGATCGCCAACGGCTCGCGAGCCAT
GGTCGCGGCGCTGGCGGAGCGGGTGCCGCATCTCGTGGTGGTGGAGATCACCGCACCGGAGGCGGTGCTGGCCGAGCGGC
TGAAGGGCAGGGGACGCGAGGGCGCGGAGAACATCGCCGCCCGGCTTGAGCGCAAAGTGCCGCCGTTTCCGGAGAGCGTC
ACGGTCATTCAGGTGCCGAACGACAGCACGCCGCGCGCCGGCATCGAGAAATTCGTCGCTGCGCTTGTCGCGCAGACCGC
CCGCCTGAGGCTGGTGCGGATGGCCATTGAGACCGGACGCCGCAACGTCGCCTTTCTGGCTCGTGGGAATACCGTTGTGG
CCGCACCGGACTATCTCGGGCCGGGACGTGTGGACCTGATCGGGGAGGGGCGCAGTATCCGCGCCGAAGTGGCCCTGGTG
GGCGATGCCTTGCTGCCGTCCGATGCCGTCGGCCTGTCGTCGGAAGCCTTCGGGGCTCTCGGCCTGCCCGAAGGCGCGGA
ACTGGTCCTCACCCGCACCCCCGTGCCCGAAAGCCGCGCCGCGCTCCGCCGTAAGATCCAGGGCGCGACGCTGGATGAGG
GCGCTTATGCGCAGGTCGTCGGAGACATCGTGGAGGGGCGTTATCCCGACAGCGAGGTCGCCGGCTTTCTCGTAGCCGCC
GACCGCAGCCTGAGTGACGACGAAGTGCTGGCGCTCGCCAAGGTGCGGGCGAAATTCGCGAGCCGCATCACATGGGACGA
GCCCATGGTGGTGGACAAGCATTCCATGGGCGGCATTCCCGGTTCCCGCATCACCATGATCGTGGTGCCGATCGTCGCCG
CGCACGGGCTCGCCATCCCCAAGACCTCCTCCCGCGCCATCACCTCGGCGGCCGGCACGGCGGACGCCATGGAGACGCTG
GCGCGCGTCGATCTCGACAGCGCCGAGGTGCGCCGGACGGTGGAACGGGCACGCGGCTGCATCGCCTGGAACGGGCGGCT
CAGTCATTCGGCCCTCGATGATGTCATGAACGCCATTACGCGGCCGCTGGGGCTCGATTCCACCCGCTGGTCGGTGGCCT
CCATCCTGTCCAAGAAGCTGGCGGCTGGCTCGACCCATGTGGTGATCGACCTGCCGTTTGGCGCCCGCGCCCGCGTGAAG
GGGGCGGGCGAAGCCCACGAGATGGCGCGCCTGTTCGAGCAGGTCGGCGCCGGGCTCGGCCTCACCGTCGAAGCCATTCC
CACCGACGGCAGCGCTCCCATCGGGCGCGGCATCGGGCCGGCTCTTGAGGTCCGGGACGTGCTCTGGGTCCTGGAGGATC
ATTCCGAAGCCCCGCCGGACCTGAAAGAGAAGGCCCTCTTCTTCGCCAGCCGCATTCTCGCCTGGGATCCGGCCGTTGGT
CCGGACAGGGCGCGCGCCCGCGCCGAGGAGCTTCTCGCTTCCGGTGCCGCCCGCGCGGCGCTGGAGCGGATCGTGGAGGC
GCAAGGGCGCTGGAGCGAGCCGGTGCGTCCCGCCCGCCTCACGCACACCGTGACCGCCCAAAATGACGGACAGGTGAGCG
ATATCGACGGGTTCGCCGTGGCCGGCATCGCTCGCCTTGCCGGCGCGCCGCTGGACAAGGGTGCCGGTATCGATCTGAAG
GCGCGGGTGGGCGACGTGGTGCGCGCGGGAGACCCGCTCTTTGTCATCCATGCCTCCACGGCTGCCGATCTCGAGGCGGC
CGCGGGCGCCGCGCTCGCGTTCGACGGCTACGGCATCATGATGGACGGGAAAGCATTCCGCAGGATCAATCCGGAGCGGT
AG

Upstream 100 bases:

>100_bases
ACACCATCGGCCCGATCGCGCAGACGGGGGTGAACTACATTTCCACCAGCAAGATCACCCAGTCGGCGCCAGCCGTCGAC
ATCGGCCTCGACGAGGCGGA

Downstream 100 bases:

>100_bases
CTCCGTGGCGCAATCTCCGGGCAAGGCCGGCGAAATATAAGGCAGGCTGGACGTAAATGCCGCTTGAAGAAGGCGGCAGG
CCAGCTACAGCCTTAGGGAG

Product: guanosine monophosphate kinase like protein

Products: NA

Alternate protein names: TdRPase

Number of amino acids: Translated: 693; Mature: 692

Protein sequence:

>693_residues
MSVMGSGLFFFVVGPSGSGKDTLIEGAKAALGPTGRYVFARRAITRPADAGGEAHEALSVDQFDAVLAQGGFLIHWEAHG
LKYGLRATLLDDMAAGRHVIANGSRAMVAALAERVPHLVVVEITAPEAVLAERLKGRGREGAENIAARLERKVPPFPESV
TVIQVPNDSTPRAGIEKFVAALVAQTARLRLVRMAIETGRRNVAFLARGNTVVAAPDYLGPGRVDLIGEGRSIRAEVALV
GDALLPSDAVGLSSEAFGALGLPEGAELVLTRTPVPESRAALRRKIQGATLDEGAYAQVVGDIVEGRYPDSEVAGFLVAA
DRSLSDDEVLALAKVRAKFASRITWDEPMVVDKHSMGGIPGSRITMIVVPIVAAHGLAIPKTSSRAITSAAGTADAMETL
ARVDLDSAEVRRTVERARGCIAWNGRLSHSALDDVMNAITRPLGLDSTRWSVASILSKKLAAGSTHVVIDLPFGARARVK
GAGEAHEMARLFEQVGAGLGLTVEAIPTDGSAPIGRGIGPALEVRDVLWVLEDHSEAPPDLKEKALFFASRILAWDPAVG
PDRARARAEELLASGAARAALERIVEAQGRWSEPVRPARLTHTVTAQNDGQVSDIDGFAVAGIARLAGAPLDKGAGIDLK
ARVGDVVRAGDPLFVIHASTAADLEAAAGAALAFDGYGIMMDGKAFRRINPER

Sequences:

>Translated_693_residues
MSVMGSGLFFFVVGPSGSGKDTLIEGAKAALGPTGRYVFARRAITRPADAGGEAHEALSVDQFDAVLAQGGFLIHWEAHG
LKYGLRATLLDDMAAGRHVIANGSRAMVAALAERVPHLVVVEITAPEAVLAERLKGRGREGAENIAARLERKVPPFPESV
TVIQVPNDSTPRAGIEKFVAALVAQTARLRLVRMAIETGRRNVAFLARGNTVVAAPDYLGPGRVDLIGEGRSIRAEVALV
GDALLPSDAVGLSSEAFGALGLPEGAELVLTRTPVPESRAALRRKIQGATLDEGAYAQVVGDIVEGRYPDSEVAGFLVAA
DRSLSDDEVLALAKVRAKFASRITWDEPMVVDKHSMGGIPGSRITMIVVPIVAAHGLAIPKTSSRAITSAAGTADAMETL
ARVDLDSAEVRRTVERARGCIAWNGRLSHSALDDVMNAITRPLGLDSTRWSVASILSKKLAAGSTHVVIDLPFGARARVK
GAGEAHEMARLFEQVGAGLGLTVEAIPTDGSAPIGRGIGPALEVRDVLWVLEDHSEAPPDLKEKALFFASRILAWDPAVG
PDRARARAEELLASGAARAALERIVEAQGRWSEPVRPARLTHTVTAQNDGQVSDIDGFAVAGIARLAGAPLDKGAGIDLK
ARVGDVVRAGDPLFVIHASTAADLEAAAGAALAFDGYGIMMDGKAFRRINPER
>Mature_692_residues
SVMGSGLFFFVVGPSGSGKDTLIEGAKAALGPTGRYVFARRAITRPADAGGEAHEALSVDQFDAVLAQGGFLIHWEAHGL
KYGLRATLLDDMAAGRHVIANGSRAMVAALAERVPHLVVVEITAPEAVLAERLKGRGREGAENIAARLERKVPPFPESVT
VIQVPNDSTPRAGIEKFVAALVAQTARLRLVRMAIETGRRNVAFLARGNTVVAAPDYLGPGRVDLIGEGRSIRAEVALVG
DALLPSDAVGLSSEAFGALGLPEGAELVLTRTPVPESRAALRRKIQGATLDEGAYAQVVGDIVEGRYPDSEVAGFLVAAD
RSLSDDEVLALAKVRAKFASRITWDEPMVVDKHSMGGIPGSRITMIVVPIVAAHGLAIPKTSSRAITSAAGTADAMETLA
RVDLDSAEVRRTVERARGCIAWNGRLSHSALDDVMNAITRPLGLDSTRWSVASILSKKLAAGSTHVVIDLPFGARARVKG
AGEAHEMARLFEQVGAGLGLTVEAIPTDGSAPIGRGIGPALEVRDVLWVLEDHSEAPPDLKEKALFFASRILAWDPAVGP
DRARARAEELLASGAARAALERIVEAQGRWSEPVRPARLTHTVTAQNDGQVSDIDGFAVAGIARLAGAPLDKGAGIDLKA
RVGDVVRAGDPLFVIHASTAADLEAAAGAALAFDGYGIMMDGKAFRRINPER

Specific function: The Enzymes Which Catalyze The Reversible Phosphorolysis Of Pyrimidine Nucleosides Are Involved In The Degradation Of These Compounds And In Their Utilization As Carbon And Energy Sources, Or In The Rescue Of Pyrimidine Bases For Nucleotide Synthesis. [C

COG id: COG0213

COG function: function code F; Thymidine phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI166158925, Length=427, Percent_Identity=28.5714285714286, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI4503445, Length=427, Percent_Identity=28.5714285714286, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI166158922, Length=427, Percent_Identity=28.5714285714286, Blast_Score=119, Evalue=1e-26,
Organism=Escherichia coli, GI1790842, Length=327, Percent_Identity=29.9694189602446, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1790532, Length=174, Percent_Identity=35.632183908046, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TYPH_AZOC5 (A8IA58)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001525383.1
- ProteinModelPortal:   A8IA58
- GeneID:   5687914
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_2467
- HOGENOM:   HBG460532
- OMA:   EFVGDHF
- ProtClustDB:   CLSK956389
- BioCyc:   ACAU438753:AZC_2467-MONOMER
- HAMAP:   MF_00703
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR008145
- InterPro:   IPR012699
- InterPro:   IPR013102
- InterPro:   IPR000053
- InterPro:   IPR017872
- InterPro:   IPR013466
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- PANTHER:   PTHR10515
- SMART:   SM00072
- SMART:   SM00941
- TIGRFAMs:   TIGR02645
- TIGRFAMs:   TIGR02322

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; PF07831 PYNP_C; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3; SSF54680 PYNP_C

EC number: =2.4.2.4

Molecular weight: Translated: 72761; Mature: 72630

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00647 THYMID_PHOSPHORYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVMGSGLFFFVVGPSGSGKDTLIEGAKAALGPTGRYVFARRAITRPADAGGEAHEALSV
CCCCCCCEEEEEECCCCCCCHHHHHCCHHHCCCCCCEEEEHHHHCCCCCCCCCHHHHCCH
DQFDAVLAQGGFLIHWEAHGLKYGLRATLLDDMAAGRHVIANGSRAMVAALAERVPHLVV
HHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCEEE
VEITAPEAVLAERLKGRGREGAENIAARLERKVPPFPESVTVIQVPNDSTPRAGIEKFVA
EEECCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHH
ALVAQTARLRLVRMAIETGRRNVAFLARGNTVVAAPDYLGPGRVDLIGEGRSIRAEVALV
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEECCCCCCCCCEEEEECCCCEEEEEEEE
GDALLPSDAVGLSSEAFGALGLPEGAELVLTRTPVPESRAALRRKIQGATLDEGAYAQVV
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHH
GDIVEGRYPDSEVAGFLVAADRSLSDDEVLALAKVRAKFASRITWDEPMVVDKHSMGGIP
HHHHHCCCCCHHHCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCC
GSRITMIVVPIVAAHGLAIPKTSSRAITSAAGTADAMETLARVDLDSAEVRRTVERARGC
CCCEEEEEEEHHHHCCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCE
IAWNGRLSHSALDDVMNAITRPLGLDSTRWSVASILSKKLAAGSTHVVIDLPFGARARVK
EEECCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEC
GAGEAHEMARLFEQVGAGLGLTVEAIPTDGSAPIGRGIGPALEVRDVLWVLEDHSEAPPD
CCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
LKEKALFFASRILAWDPAVGPDRARARAEELLASGAARAALERIVEAQGRWSEPVRPARL
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCEE
THTVTAQNDGQVSDIDGFAVAGIARLAGAPLDKGAGIDLKARVGDVVRAGDPLFVIHAST
EEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEHHHHCHHHCCCCCEEEEECCC
AADLEAAAGAALAFDGYGIMMDGKAFRRINPER
CCCHHHHCCCEEEECCEEEEECCHHHCCCCCCC
>Mature Secondary Structure 
SVMGSGLFFFVVGPSGSGKDTLIEGAKAALGPTGRYVFARRAITRPADAGGEAHEALSV
CCCCCCEEEEEECCCCCCCHHHHHCCHHHCCCCCCEEEEHHHHCCCCCCCCCHHHHCCH
DQFDAVLAQGGFLIHWEAHGLKYGLRATLLDDMAAGRHVIANGSRAMVAALAERVPHLVV
HHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCEEE
VEITAPEAVLAERLKGRGREGAENIAARLERKVPPFPESVTVIQVPNDSTPRAGIEKFVA
EEECCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHH
ALVAQTARLRLVRMAIETGRRNVAFLARGNTVVAAPDYLGPGRVDLIGEGRSIRAEVALV
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEECCCCCCCCCEEEEECCCCEEEEEEEE
GDALLPSDAVGLSSEAFGALGLPEGAELVLTRTPVPESRAALRRKIQGATLDEGAYAQVV
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHH
GDIVEGRYPDSEVAGFLVAADRSLSDDEVLALAKVRAKFASRITWDEPMVVDKHSMGGIP
HHHHHCCCCCHHHCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCC
GSRITMIVVPIVAAHGLAIPKTSSRAITSAAGTADAMETLARVDLDSAEVRRTVERARGC
CCCEEEEEEEHHHHCCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCE
IAWNGRLSHSALDDVMNAITRPLGLDSTRWSVASILSKKLAAGSTHVVIDLPFGARARVK
EEECCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEC
GAGEAHEMARLFEQVGAGLGLTVEAIPTDGSAPIGRGIGPALEVRDVLWVLEDHSEAPPD
CCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
LKEKALFFASRILAWDPAVGPDRARARAEELLASGAARAALERIVEAQGRWSEPVRPARL
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCEE
THTVTAQNDGQVSDIDGFAVAGIARLAGAPLDKGAGIDLKARVGDVVRAGDPLFVIHAST
EEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEHHHHCHHHCCCCCEEEEECCC
AADLEAAAGAALAFDGYGIMMDGKAFRRINPER
CCCHHHHCCCEEEECCEEEEECCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA