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The map label for this gene is mcpA [H]

Identifier: 158424090

GI number: 158424090

Start: 2800652

End: 2802733

Strand: Reverse

Name: mcpA [H]

Synonym: AZC_2466

Alternate gene names: 158424090

Gene position: 2802733-2800652 (Counterclockwise)

Preceding gene: 158424091

Following gene: 158424088

Centisome position: 52.19

GC content: 68.06

Gene sequence:

>2082_bases
GTGACGATCAAGCGCCTGCTATCTCTGTCCATCCTGTGTGTTGCCGCGATAGCCTGCGCGCTATCGATCATGATGGCCGT
GCGGCAGTACAACCAGCTCACCCTGAGCCAGGATGCGCGCCTCCGCCTGGAGGTGGTCCGTGCGCTTGCCGACGTGCCGC
GGGTGATGAATCCGGAGCGGGGCCTGCTCACGCTCGCCATCCAGACCATGACGAGCGATCAGGTCAGCCGCACCGATCTG
CCGGCCTATCGCGAGGCCTCCGAAAAGGCGCTGGCCGCCATCCGCGCCCGCACCGAGGCGACGGTCGGCCAGCTTGCCGA
CGCGGACGCCATCATCGCGGTGTCGAAGCAGCTGGACGAGGCCTATCGCCAGATCAAGGACACCCAGTCCAGCGCCATGG
CCCTGCCCATCAACCAGCGCGGCACGGCGGCCAATGTGGTGACCGACAAGGCGAGCGCCATGAATACGCTTGCCGCGCAG
GCGCTCAACACGCAGCTGCGCAAGATGGCGCCCGCCAACGGCGTCGCCTTCGCCTGGGGCAATGTCGGTGCCGCTGTCCT
GGATCTGCGTGATTACGGCGGACGTCAGGCGGGCATGCTGCAGTCGCTGGTGGCGGCGCACAAGCCGGTGACGCCCGAGC
AGCGCATCCAGTTCTACACCCTCCAGGGCCGCGTGGATCAGCTCTGGGGTGGCCTGTGGGAACTGCGGAACGTGACGGGC
GGTGCGCCCTCCTTCAAGCCGGCGCTCGACAAGGCGAACAGCGACTACATCCAGTTCTTCGCCGGCCTGCGGGACGAGAT
GGCGAAGTATTTCGAGACGGGCGACTTCCCCATCGACGGCAGCACCTATCGCGAGCGCACCTTCCGCATGTGGAACGTCG
TCATCGCCTTGCGCGACGCCGCGTTCGAAGGCTCCGAGCTTGCCATCGACAGTGCCATCGCCTCCGCGCGCCAGAACCTG
ATCCTCTCGGTCGTCGGCCTCGTGGTGGTGGTGCTTGCTGCCATTGCCGTGCTCGTGGTGGTGCAGCGCCGGGCCATTCG
TCCTCTGTTCCAGATGACGGCGGCCATCGGCCGGATCGCCGACGGCGAGCTGGAGACCGAAATCCCCGGTGTCGGCCGCA
AGGACGAAATCGGTCATATGGCCAGCTCCGTGCAGGTGTTCAAGGACAGCCTGCTGCGCAACAGCGCGCTGGAGGCGGAA
ACCGCCGCCGCCCGAGCGCGTTCGGAGGCCGAGCGCCGCGATGCCATGCAGCAGCTCGCGGATCTGTTCGAGACCAATGT
GGGCGGCATCATCGGCGCCGTGGGGGCTTCCGCCGACCAGCTCAAGGCCTCGGCACAGGTGCTCTCGCAGAGCGCCGACG
ACACCGCCGGCCGCTCGAACACCGTTGCCGCTGCGGCCGAGCAGGCGGCGGCGAACGTCAACGTCGTCGCCTCCTCTGCG
GAGGAACTCGGCAGCTCCGTGCAGGAAATCCGCCGGCAGGTGCAGCAGGCGGCGGACGTGTCCATGACCGCCGTGAACGA
GGCGCATGCCACGGGCGAGATCGTCCGCGAACTCTCGCTGGCTGCGGCCAAGATCAGCGACATCCTGAACCTCATCAGCT
CGATCGCCGGCCAGACCAACCTCCTTGCCCTCAATGCCACCATCGAGGCGGCGCGTGCGGGTGAGGCAGGCAAGGGCTTC
GCAGTGGTGGCGAGCGAGGTGAAGGAACTCGCCGACCAGACGGCCAAGGCCACCGCCGAGATCTCGGGGCAGGTGGGCGC
CATCCAGTCCACCACCGGCAAGGCGGTGGATGCCATCGGCCGTATCGCCACCACCATTCAGGAGATGAACACCTACGCCA
ATGCCGTCGCGGCGGCCGTGGCGCAGCAGGGTGTCGCCACCGGCGAGATCGTGCGCAGCGTCGCGGAAGCGTCCGCGGGC
ACGAGCGAGGTGACCGGCAACATCACTGGCGTTGCACAGACCGCGCAGAGCGTGGGGTCTGCGGCGGGGCAGGTGCTGAC
GCTGTCCTCCGACCTCCAGGGCCAGGCGCAGGCGCTGAGCGCGGAAATGGCGCGCTTCCTCCAGACGGTCCGGGCCGCCT
GA

Upstream 100 bases:

>100_bases
GCAATCTCCGGGCAAGGCCGGCGAAATATAAGGCAGGCTGGACGTAAATGCCGCTTGAAGAAGGCGGCAGGCCAGCTACA
GCCTTAGGGAGACGCCACCC

Downstream 100 bases:

>100_bases
GTCGCATCGCCCCGCAAGAGACACGCAGCGGGCGGCTTCGGCCGCCCGTCTGCGTTTGGAGGCACGTTCAGGCGCTGGCG
ATCTGACCGCCCCAGACCTG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 693; Mature: 692

Protein sequence:

>693_residues
MTIKRLLSLSILCVAAIACALSIMMAVRQYNQLTLSQDARLRLEVVRALADVPRVMNPERGLLTLAIQTMTSDQVSRTDL
PAYREASEKALAAIRARTEATVGQLADADAIIAVSKQLDEAYRQIKDTQSSAMALPINQRGTAANVVTDKASAMNTLAAQ
ALNTQLRKMAPANGVAFAWGNVGAAVLDLRDYGGRQAGMLQSLVAAHKPVTPEQRIQFYTLQGRVDQLWGGLWELRNVTG
GAPSFKPALDKANSDYIQFFAGLRDEMAKYFETGDFPIDGSTYRERTFRMWNVVIALRDAAFEGSELAIDSAIASARQNL
ILSVVGLVVVVLAAIAVLVVVQRRAIRPLFQMTAAIGRIADGELETEIPGVGRKDEIGHMASSVQVFKDSLLRNSALEAE
TAAARARSEAERRDAMQQLADLFETNVGGIIGAVGASADQLKASAQVLSQSADDTAGRSNTVAAAAEQAAANVNVVASSA
EELGSSVQEIRRQVQQAADVSMTAVNEAHATGEIVRELSLAAAKISDILNLISSIAGQTNLLALNATIEAARAGEAGKGF
AVVASEVKELADQTAKATAEISGQVGAIQSTTGKAVDAIGRIATTIQEMNTYANAVAAAVAQQGVATGEIVRSVAEASAG
TSEVTGNITGVAQTAQSVGSAAGQVLTLSSDLQGQAQALSAEMARFLQTVRAA

Sequences:

>Translated_693_residues
MTIKRLLSLSILCVAAIACALSIMMAVRQYNQLTLSQDARLRLEVVRALADVPRVMNPERGLLTLAIQTMTSDQVSRTDL
PAYREASEKALAAIRARTEATVGQLADADAIIAVSKQLDEAYRQIKDTQSSAMALPINQRGTAANVVTDKASAMNTLAAQ
ALNTQLRKMAPANGVAFAWGNVGAAVLDLRDYGGRQAGMLQSLVAAHKPVTPEQRIQFYTLQGRVDQLWGGLWELRNVTG
GAPSFKPALDKANSDYIQFFAGLRDEMAKYFETGDFPIDGSTYRERTFRMWNVVIALRDAAFEGSELAIDSAIASARQNL
ILSVVGLVVVVLAAIAVLVVVQRRAIRPLFQMTAAIGRIADGELETEIPGVGRKDEIGHMASSVQVFKDSLLRNSALEAE
TAAARARSEAERRDAMQQLADLFETNVGGIIGAVGASADQLKASAQVLSQSADDTAGRSNTVAAAAEQAAANVNVVASSA
EELGSSVQEIRRQVQQAADVSMTAVNEAHATGEIVRELSLAAAKISDILNLISSIAGQTNLLALNATIEAARAGEAGKGF
AVVASEVKELADQTAKATAEISGQVGAIQSTTGKAVDAIGRIATTIQEMNTYANAVAAAVAQQGVATGEIVRSVAEASAG
TSEVTGNITGVAQTAQSVGSAAGQVLTLSSDLQGQAQALSAEMARFLQTVRAA
>Mature_692_residues
TIKRLLSLSILCVAAIACALSIMMAVRQYNQLTLSQDARLRLEVVRALADVPRVMNPERGLLTLAIQTMTSDQVSRTDLP
AYREASEKALAAIRARTEATVGQLADADAIIAVSKQLDEAYRQIKDTQSSAMALPINQRGTAANVVTDKASAMNTLAAQA
LNTQLRKMAPANGVAFAWGNVGAAVLDLRDYGGRQAGMLQSLVAAHKPVTPEQRIQFYTLQGRVDQLWGGLWELRNVTGG
APSFKPALDKANSDYIQFFAGLRDEMAKYFETGDFPIDGSTYRERTFRMWNVVIALRDAAFEGSELAIDSAIASARQNLI
LSVVGLVVVVLAAIAVLVVVQRRAIRPLFQMTAAIGRIADGELETEIPGVGRKDEIGHMASSVQVFKDSLLRNSALEAET
AAARARSEAERRDAMQQLADLFETNVGGIIGAVGASADQLKASAQVLSQSADDTAGRSNTVAAAAEQAAANVNVVASSAE
ELGSSVQEIRRQVQQAADVSMTAVNEAHATGEIVRELSLAAAKISDILNLISSIAGQTNLLALNATIEAARAGEAGKGFA
VVASEVKELADQTAKATAEISGQVGAIQSTTGKAVDAIGRIATTIQEMNTYANAVAAAVAQQGVATGEIVRSVAEASAGT
SEVTGNITGVAQTAQSVGSAAGQVLTLSSDLQGQAQALSAEMARFLQTVRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=397, Percent_Identity=26.1964735516373, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1787690, Length=463, Percent_Identity=26.7818574514039, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788194, Length=382, Percent_Identity=28.0104712041885, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1788195, Length=314, Percent_Identity=28.343949044586, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789453, Length=190, Percent_Identity=34.7368421052632, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 72693; Mature: 72562

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKRLLSLSILCVAAIACALSIMMAVRQYNQLTLSQDARLRLEVVRALADVPRVMNPER
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
GLLTLAIQTMTSDQVSRTDLPAYREASEKALAAIRARTEATVGQLADADAIIAVSKQLDE
CEEEEEEEHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AYRQIKDTQSSAMALPINQRGTAANVVTDKASAMNTLAAQALNTQLRKMAPANGVAFAWG
HHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
NVGAAVLDLRDYGGRQAGMLQSLVAAHKPVTPEQRIQFYTLQGRVDQLWGGLWELRNVTG
CCCHHEEEHHHCCCCHHHHHHHHHHHCCCCCHHHHEEEEEECCCHHHHHHHHHHHHHCCC
GAPSFKPALDKANSDYIQFFAGLRDEMAKYFETGDFPIDGSTYRERTFRMWNVVIALRDA
CCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AFEGSELAIDSAIASARQNLILSVVGLVVVVLAAIAVLVVVQRRAIRPLFQMTAAIGRIA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DGELETEIPGVGRKDEIGHMASSVQVFKDSLLRNSALEAETAAARARSEAERRDAMQQLA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLFETNVGGIIGAVGASADQLKASAQVLSQSADDTAGRSNTVAAAAEQAAANVNVVASSA
HHHHCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHEEHHH
EELGSSVQEIRRQVQQAADVSMTAVNEAHATGEIVRELSLAAAKISDILNLISSIAGQTN
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LLALNATIEAARAGEAGKGFAVVASEVKELADQTAKATAEISGQVGAIQSTTGKAVDAIG
EEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
RIATTIQEMNTYANAVAAAVAQQGVATGEIVRSVAEASAGTSEVTGNITGVAQTAQSVGS
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHH
AAGQVLTLSSDLQGQAQALSAEMARFLQTVRAA
HCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TIKRLLSLSILCVAAIACALSIMMAVRQYNQLTLSQDARLRLEVVRALADVPRVMNPER
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
GLLTLAIQTMTSDQVSRTDLPAYREASEKALAAIRARTEATVGQLADADAIIAVSKQLDE
CEEEEEEEHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AYRQIKDTQSSAMALPINQRGTAANVVTDKASAMNTLAAQALNTQLRKMAPANGVAFAWG
HHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
NVGAAVLDLRDYGGRQAGMLQSLVAAHKPVTPEQRIQFYTLQGRVDQLWGGLWELRNVTG
CCCHHEEEHHHCCCCHHHHHHHHHHHCCCCCHHHHEEEEEECCCHHHHHHHHHHHHHCCC
GAPSFKPALDKANSDYIQFFAGLRDEMAKYFETGDFPIDGSTYRERTFRMWNVVIALRDA
CCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AFEGSELAIDSAIASARQNLILSVVGLVVVVLAAIAVLVVVQRRAIRPLFQMTAAIGRIA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DGELETEIPGVGRKDEIGHMASSVQVFKDSLLRNSALEAETAAARARSEAERRDAMQQLA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLFETNVGGIIGAVGASADQLKASAQVLSQSADDTAGRSNTVAAAAEQAAANVNVVASSA
HHHHCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHEEHHH
EELGSSVQEIRRQVQQAADVSMTAVNEAHATGEIVRELSLAAAKISDILNLISSIAGQTN
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LLALNATIEAARAGEAGKGFAVVASEVKELADQTAKATAEISGQVGAIQSTTGKAVDAIG
EEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
RIATTIQEMNTYANAVAAAVAQQGVATGEIVRSVAEASAGTSEVTGNITGVAQTAQSVGS
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHH
AAGQVLTLSSDLQGQAQALSAEMARFLQTVRAA
HCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]