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The map label for this gene is gntR [H]

Identifier: 158424068

GI number: 158424068

Start: 2779989

End: 2780711

Strand: Reverse

Name: gntR [H]

Synonym: AZC_2444

Alternate gene names: 158424068

Gene position: 2780711-2779989 (Counterclockwise)

Preceding gene: 158424075

Following gene: 158424067

Centisome position: 51.78

GC content: 64.87

Gene sequence:

>723_bases
ATGAGTGCGCGAATGAGCAGTATCCGTGCACAGGATGACGCGGAGTGCGCGCCTTTTGGGCAAGACGGCCTCCGCAGCGC
CGCGCCCACACTGGCCGAGAAGCTGCGCGGAGAGCTTGAGACCGCCATCGCCGCCGGGCGTCTTGAGCCCGGCAGCCGTC
TCGATGAGCAGGAAATCGCTGCCCGCTATGGGGTTTCCCGCACGCCGGTGCGCGAGGCGTTCCGCCTTCTCGCCGCCAGC
GGTCTGGTCGAACTGCGCGGCCGGCAAGGGGCGGTGGTGCGCTCAATTGGTGCGCATGCGCTGATCGAGATGTTTCAGGT
GATGGCAGAGATGGAGGGGCTGTGTGCCCGCCTCGCCGCGCGGCGCATCACGCCGGCCCAGATGGACAAGCTGAGGGCCA
TCCACGAGAAGCTGGAACAGGTCGCAACCCTAAAGGACATCGACCTTTTCTACGACGTGAACCAGGAGTTTCACGAGGCG
CTCTATGAGGCTTCGGCGAACGCCTTCCTAGCCGACCAGACCCGCCGGCTGCGCAATCAGGTGGCCGCTTATCGGCGCCG
TGTCACCCGGATGCCGACCCGCATCTCGGATACCCTGCGCGAGCATGCGGAGGTGATTGCGGCGATTGCCGACCATGATG
CGGAGCGGGCCCACAAGGCCATGCGGGACCATGTGAATCTGTTGGGCGATAATTTGCTGGATTTCCTCGCCGCCTTTGGA
TGA

Upstream 100 bases:

>100_bases
CCGCCATGTGGGCCTTACGCGGCGCCGACATTTGCTTGCGGTGGCGAGTTGGGAGAGACTGGTGGTGAGCGACCCGCCTT
TATGTATACCGAGGAAGAGA

Downstream 100 bases:

>100_bases
GCGCGAGTGAGGCAAGTTGGTATGCAATTTGCTAGCTATTGTATATCCATTTCGCCCGGAGACCTGCCTTGAAGTTGGAC
CTCACGAACAAGACCGCCCT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MSARMSSIRAQDDAECAPFGQDGLRSAAPTLAEKLRGELETAIAAGRLEPGSRLDEQEIAARYGVSRTPVREAFRLLAAS
GLVELRGRQGAVVRSIGAHALIEMFQVMAEMEGLCARLAARRITPAQMDKLRAIHEKLEQVATLKDIDLFYDVNQEFHEA
LYEASANAFLADQTRRLRNQVAAYRRRVTRMPTRISDTLREHAEVIAAIADHDAERAHKAMRDHVNLLGDNLLDFLAAFG

Sequences:

>Translated_240_residues
MSARMSSIRAQDDAECAPFGQDGLRSAAPTLAEKLRGELETAIAAGRLEPGSRLDEQEIAARYGVSRTPVREAFRLLAAS
GLVELRGRQGAVVRSIGAHALIEMFQVMAEMEGLCARLAARRITPAQMDKLRAIHEKLEQVATLKDIDLFYDVNQEFHEA
LYEASANAFLADQTRRLRNQVAAYRRRVTRMPTRISDTLREHAEVIAAIADHDAERAHKAMRDHVNLLGDNLLDFLAAFG
>Mature_239_residues
SARMSSIRAQDDAECAPFGQDGLRSAAPTLAEKLRGELETAIAAGRLEPGSRLDEQEIAARYGVSRTPVREAFRLLAASG
LVELRGRQGAVVRSIGAHALIEMFQVMAEMEGLCARLAARRITPAQMDKLRAIHEKLEQVATLKDIDLFYDVNQEFHEAL
YEASANAFLADQTRRLRNQVAAYRRRVTRMPTRISDTLREHAEVIAAIADHDAERAHKAMRDHVNLLGDNLLDFLAAFG

Specific function: Unknown

COG id: COG1802

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787821, Length=184, Percent_Identity=27.7173913043478, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87081914, Length=148, Percent_Identity=29.0540540540541, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082149, Length=195, Percent_Identity=29.7435897435897, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI48994961, Length=224, Percent_Identity=30.3571428571429, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000485
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26635; Mature: 26504

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARMSSIRAQDDAECAPFGQDGLRSAAPTLAEKLRGELETAIAAGRLEPGSRLDEQEIA
CCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
ARYGVSRTPVREAFRLLAASGLVELRGRQGAVVRSIGAHALIEMFQVMAEMEGLCARLAA
HHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRITPAQMDKLRAIHEKLEQVATLKDIDLFYDVNQEFHEALYEASANAFLADQTRRLRNQ
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHH
VAAYRRRVTRMPTRISDTLREHAEVIAAIADHDAERAHKAMRDHVNLLGDNLLDFLAAFG
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SARMSSIRAQDDAECAPFGQDGLRSAAPTLAEKLRGELETAIAAGRLEPGSRLDEQEIA
CCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
ARYGVSRTPVREAFRLLAASGLVELRGRQGAVVRSIGAHALIEMFQVMAEMEGLCARLAA
HHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRITPAQMDKLRAIHEKLEQVATLKDIDLFYDVNQEFHEALYEASANAFLADQTRRLRNQ
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHH
VAAYRRRVTRMPTRISDTLREHAEVIAAIADHDAERAHKAMRDHVNLLGDNLLDFLAAFG
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]