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The map label for this gene is siaT [H]

Identifier: 158424042

GI number: 158424042

Start: 2745788

End: 2747194

Strand: Direct

Name: siaT [H]

Synonym: AZC_2418

Alternate gene names: 158424042

Gene position: 2745788-2747194 (Clockwise)

Preceding gene: 158424041

Following gene: 158424043

Centisome position: 51.13

GC content: 65.03

Gene sequence:

>1407_bases
ATGTGGCTGCTGATCGGAGCCTTCCTCTCCCTCATGCTGTTCGGCGTGCCGGTGGCGATTTCCATGGCGGTGTCCTCGCT
GCTTTACATCGCCGTCTCCGGCACCGTGCCGGACGTGGTGGTGGCGCAGCGGATGATCGCCGGCGTCGAGAGCTTCCCGC
TCCTCGCCGTGCCCTTCTTCATCCTCGCAGGCAATCTCATGAACATCGCCGGCGTGACGGGACGCATCTATTCCTTCGCC
GTGGCGCTGGTGGGCTGGATGCGCGGCGGCCTCGGGCAAGTGAACATCATCGGCTCGGTGATCTTCTCGGGCATGTCCGG
CACGGCCATCGCGGATGCTGCCGGCCTCGGCACCATCGAGATCAAGGCCATGAAGGACCATGGCTATTCGACTGAATTCT
CGGTCGGTGTAACAGCGGCCTCCGCGACCCTCGGGCCCATCATCCCGCCATCCCTGCCCTTCGTGATCTATGGCATGCTC
GCCAATGTCTCGATCGGCGCGCTCTTCCTCGGCGGTGTCATTCCCGGCGCGGTGATGACGCTCATGATGATGGCGACCGT
CGCCTGGTTCGCGCACCGCAACAAATGGGGGAGCGACGCCAAATTCTCCTGGCGCCAGCTCGGCGGGGCGGGGCTTGAGG
TCTTCGTGGTGGCGCTGTTTCCCATCGGCGTCTACGTGCTGGTGGAGCTCGGCCTCTCCATCAACGCCTCGGTGATGATT
GCGCTCGCGATCCTGCTGGCGGCGGACTGGTACTTCGACTTCTCCGCCGTGATGGCGCTGATGGCGCCGGTCATCCTCAT
CGGCGGCATGACGCTCGGCTGGTTCACGCCGACGGAAGCCGCCGTGGCTGCGGTGATCTGGTCGCTCTTCCTCGGTCTCG
TGCGCTACCGCTCCATGACGCTGCGCGCGCTCGCCAAGGCGACCTTCGACACCATCGAGACCACCGCCTCGGTGCTGTTC
ATCGTCACGGCCGCCTCCATTTTTGCCTGGCTCCTCACCGCCAGCCAGGCGGCACAGGCCCTCTCGGATGCCATCCTCGG
CTTCACCCAGAACAAATGGGTGTTCCTGGCGCTGGCGAACCTGCTGATCCTGTTCGTGGGCTGCTTCATCGACACCATCG
CCGCCATCACCATCCTGGTGCCGATCCTGCTGCCCATCGTGCTGAAGCTCGGCATCGATCCGATCCACTTCGGGCTCATC
ATGACGCTGAACCTGATGATCGGTCTGCTGCACCCGCCGCTCGGCATGGTGCTGTTCGTGCTGGCGCGGGTGGCGAAGCT
CTCGGTGGAGCGCACCACCATGGCCATCCTGCCGTGGCTGGTGCCGCTGATGCTGGCGCTTCTGGCCATCACCTACATTC
CCGAGCTCACCCTCTGGCTGCCGCGCATGGCGGGCCTCGGACGCTGA

Upstream 100 bases:

>100_bases
CATGCTGCTGCGCGCCATCCAGGTGGCGATCGCCAATTTCCGGCGCGGCTACAGCGTGCTCGAACGCCCCGAAGCCTTTG
ACAATCTGGAGGCCTGATCC

Downstream 100 bases:

>100_bases
CGCAAAAGGAACCGGCGGGGCCTGTCGCCGCCGGTTCACCATGGTGCAGCGCAAGGAATGTGTGGCACCGACATCACGTA
TTCACAAAAACGTGATCAAA

Product: C4-dicarboxylate ABC transporter permease

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MWLLIGAFLSLMLFGVPVAISMAVSSLLYIAVSGTVPDVVVAQRMIAGVESFPLLAVPFFILAGNLMNIAGVTGRIYSFA
VALVGWMRGGLGQVNIIGSVIFSGMSGTAIADAAGLGTIEIKAMKDHGYSTEFSVGVTAASATLGPIIPPSLPFVIYGML
ANVSIGALFLGGVIPGAVMTLMMMATVAWFAHRNKWGSDAKFSWRQLGGAGLEVFVVALFPIGVYVLVELGLSINASVMI
ALAILLAADWYFDFSAVMALMAPVILIGGMTLGWFTPTEAAVAAVIWSLFLGLVRYRSMTLRALAKATFDTIETTASVLF
IVTAASIFAWLLTASQAAQALSDAILGFTQNKWVFLALANLLILFVGCFIDTIAAITILVPILLPIVLKLGIDPIHFGLI
MTLNLMIGLLHPPLGMVLFVLARVAKLSVERTTMAILPWLVPLMLALLAITYIPELTLWLPRMAGLGR

Sequences:

>Translated_468_residues
MWLLIGAFLSLMLFGVPVAISMAVSSLLYIAVSGTVPDVVVAQRMIAGVESFPLLAVPFFILAGNLMNIAGVTGRIYSFA
VALVGWMRGGLGQVNIIGSVIFSGMSGTAIADAAGLGTIEIKAMKDHGYSTEFSVGVTAASATLGPIIPPSLPFVIYGML
ANVSIGALFLGGVIPGAVMTLMMMATVAWFAHRNKWGSDAKFSWRQLGGAGLEVFVVALFPIGVYVLVELGLSINASVMI
ALAILLAADWYFDFSAVMALMAPVILIGGMTLGWFTPTEAAVAAVIWSLFLGLVRYRSMTLRALAKATFDTIETTASVLF
IVTAASIFAWLLTASQAAQALSDAILGFTQNKWVFLALANLLILFVGCFIDTIAAITILVPILLPIVLKLGIDPIHFGLI
MTLNLMIGLLHPPLGMVLFVLARVAKLSVERTTMAILPWLVPLMLALLAITYIPELTLWLPRMAGLGR
>Mature_468_residues
MWLLIGAFLSLMLFGVPVAISMAVSSLLYIAVSGTVPDVVVAQRMIAGVESFPLLAVPFFILAGNLMNIAGVTGRIYSFA
VALVGWMRGGLGQVNIIGSVIFSGMSGTAIADAAGLGTIEIKAMKDHGYSTEFSVGVTAASATLGPIIPPSLPFVIYGML
ANVSIGALFLGGVIPGAVMTLMMMATVAWFAHRNKWGSDAKFSWRQLGGAGLEVFVVALFPIGVYVLVELGLSINASVMI
ALAILLAADWYFDFSAVMALMAPVILIGGMTLGWFTPTEAAVAAVIWSLFLGLVRYRSMTLRALAKATFDTIETTASVLF
IVTAASIFAWLLTASQAAQALSDAILGFTQNKWVFLALANLLILFVGCFIDTIAAITILVPILLPIVLKLGIDPIHFGLI
MTLNLMIGLLHPPLGMVLFVLARVAKLSVERTTMAILPWLVPLMLALLAITYIPELTLWLPRMAGLGR

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=417, Percent_Identity=33.0935251798561, Blast_Score=190, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 49626; Mature: 49626

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWLLIGAFLSLMLFGVPVAISMAVSSLLYIAVSGTVPDVVVAQRMIAGVESFPLLAVPFF
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHH
ILAGNLMNIAGVTGRIYSFAVALVGWMRGGLGQVNIIGSVIFSGMSGTAIADAAGLGTIE
HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHCCCCEEE
IKAMKDHGYSTEFSVGVTAASATLGPIIPPSLPFVIYGMLANVSIGALFLGGVIPGAVMT
EEEEECCCCCCEEEEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMMMATVAWFAHRNKWGSDAKFSWRQLGGAGLEVFVVALFPIGVYVLVELGLSINASVMI
HHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ALAILLAADWYFDFSAVMALMAPVILIGGMTLGWFTPTEAAVAAVIWSLFLGLVRYRSMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LRALAKATFDTIETTASVLFIVTAASIFAWLLTASQAAQALSDAILGFTQNKWVFLALAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LLILFVGCFIDTIAAITILVPILLPIVLKLGIDPIHFGLIMTLNLMIGLLHPPLGMVLFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
LARVAKLSVERTTMAILPWLVPLMLALLAITYIPELTLWLPRMAGLGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MWLLIGAFLSLMLFGVPVAISMAVSSLLYIAVSGTVPDVVVAQRMIAGVESFPLLAVPFF
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHH
ILAGNLMNIAGVTGRIYSFAVALVGWMRGGLGQVNIIGSVIFSGMSGTAIADAAGLGTIE
HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHCCCCEEE
IKAMKDHGYSTEFSVGVTAASATLGPIIPPSLPFVIYGMLANVSIGALFLGGVIPGAVMT
EEEEECCCCCCEEEEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMMMATVAWFAHRNKWGSDAKFSWRQLGGAGLEVFVVALFPIGVYVLVELGLSINASVMI
HHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ALAILLAADWYFDFSAVMALMAPVILIGGMTLGWFTPTEAAVAAVIWSLFLGLVRYRSMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LRALAKATFDTIETTASVLFIVTAASIFAWLLTASQAAQALSDAILGFTQNKWVFLALAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LLILFVGCFIDTIAAITILVPILLPIVLKLGIDPIHFGLIMTLNLMIGLLHPPLGMVLFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
LARVAKLSVERTTMAILPWLVPLMLALLAITYIPELTLWLPRMAGLGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]