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The map label for this gene is fabH [H]

Identifier: 158423918

GI number: 158423918

Start: 2619595

End: 2620569

Strand: Reverse

Name: fabH [H]

Synonym: AZC_2294

Alternate gene names: 158423918

Gene position: 2620569-2619595 (Counterclockwise)

Preceding gene: 158423919

Following gene: 158423917

Centisome position: 48.8

GC content: 67.59

Gene sequence:

>975_bases
GTGATCGGCATTCATTCTGTGGTTCGCGGCGTGGGGTCCTATCTTCCGCAGAAGGTTCTCACCAATGCCGATCTGGCCGA
AATGGTGGACACCTCTGACGAGTGGATCGTCCAGCGCACCGGCATCAAGGAACGGCACGTCGCGGCCGAGGGCGAGTTCA
CCTCCGCCCTGGGGCTGAAGGCGGCGCAGGCGGCACTCGCTGACGCGGGCCTTGTGGCCGACGACATCGACCTCATCATC
CTTGCCACGTCGACGCCCGACCAGACCTTCCCGGCGACCGCGGTCACCATCCAGAGCGAGCTCGGCATCACGCGCGGTGC
GGCCTTCGACCTCCAGGCCGTGTGCTCGGGCTTCGTCTTCGCGATCGCGACGGCCGATGCCCATCTGCGCACCGGCGCCT
TCAAGCGCGCGCTGGTGATCGGCGCGGAGACTTTCTCGCGCATCCTCGACTGGAATGACCGCGGCACCTGCGTGCTGTTC
GGCGACGGGGCCGGTGCCATCGTGCTCGAAGGGGTGCCGGCGGACGAGGCGAAGGGCAGGGGCGTTCTCACCTCCCACCT
GCGCTCCGACGGCCGCCACCGCTCCAAGCTGTTCGTGGACGGCGGGCCCTCCAGCACGGGCACCGTCGGTCATCTGCGCA
TGGAAGGCCGCGAGGTCTTCAAGCACGCCGTCGGCATGATCACGGACGTGATCGTGGACGCCTTTGCCGCCACCGGCGAG
AGCGCGGAGACCATCGACTGGTTCGTCCCCCATCAGGCCAATCGTCGCATCATCGACGCCAGCGCGCAGAAGCTCGGGAT
TGCGCCGGAAAAGGTGGTCACCACCGTCCAGTCGCACGGAAATACCTCTGCCGCCTCGATTCCGCTCGCGCTCGACGTCG
CCCGGAAGGACGGGCGCATCAAGCCGGGTGACCTCGTTCTGCTCGAGGCGATGGGCGGCGGCTTCACCTGGGGCTCCGCT
CTTCTGCGCTGGTAA

Upstream 100 bases:

>100_bases
TGGTCCGTCACCGGCTTCTGGAACGGATCGAAAAAAGCATCGTGACGCGCCTGCCTGCGGCAGGCCGGGGGAGCGAGCCG
GTGGAGGCGGAAGGTTCATC

Downstream 100 bases:

>100_bases
TTTGTTCCTGACGCAAATAAAGCGTTAAGAACATTGACCTTGCTGCGGTCCACTGGCTAGGGTCGCGGCAGTGGGGGTGT
CCTCGAGGGGTCGGGAAGAC

Product: beta-ketoacyl-acyl carrier protein synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MIGIHSVVRGVGSYLPQKVLTNADLAEMVDTSDEWIVQRTGIKERHVAAEGEFTSALGLKAAQAALADAGLVADDIDLII
LATSTPDQTFPATAVTIQSELGITRGAAFDLQAVCSGFVFAIATADAHLRTGAFKRALVIGAETFSRILDWNDRGTCVLF
GDGAGAIVLEGVPADEAKGRGVLTSHLRSDGRHRSKLFVDGGPSSTGTVGHLRMEGREVFKHAVGMITDVIVDAFAATGE
SAETIDWFVPHQANRRIIDASAQKLGIAPEKVVTTVQSHGNTSAASIPLALDVARKDGRIKPGDLVLLEAMGGGFTWGSA
LLRW

Sequences:

>Translated_324_residues
MIGIHSVVRGVGSYLPQKVLTNADLAEMVDTSDEWIVQRTGIKERHVAAEGEFTSALGLKAAQAALADAGLVADDIDLII
LATSTPDQTFPATAVTIQSELGITRGAAFDLQAVCSGFVFAIATADAHLRTGAFKRALVIGAETFSRILDWNDRGTCVLF
GDGAGAIVLEGVPADEAKGRGVLTSHLRSDGRHRSKLFVDGGPSSTGTVGHLRMEGREVFKHAVGMITDVIVDAFAATGE
SAETIDWFVPHQANRRIIDASAQKLGIAPEKVVTTVQSHGNTSAASIPLALDVARKDGRIKPGDLVLLEAMGGGFTWGSA
LLRW
>Mature_324_residues
MIGIHSVVRGVGSYLPQKVLTNADLAEMVDTSDEWIVQRTGIKERHVAAEGEFTSALGLKAAQAALADAGLVADDIDLII
LATSTPDQTFPATAVTIQSELGITRGAAFDLQAVCSGFVFAIATADAHLRTGAFKRALVIGAETFSRILDWNDRGTCVLF
GDGAGAIVLEGVPADEAKGRGVLTSHLRSDGRHRSKLFVDGGPSSTGTVGHLRMEGREVFKHAVGMITDVIVDAFAATGE
SAETIDWFVPHQANRRIIDASAQKLGIAPEKVVTTVQSHGNTSAASIPLALDVARKDGRIKPGDLVLLEAMGGGFTWGSA
LLRW

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=325, Percent_Identity=49.5384615384615, Blast_Score=313, Evalue=7e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 34093; Mature: 34093

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGIHSVVRGVGSYLPQKVLTNADLAEMVDTSDEWIVQRTGIKERHVAAEGEFTSALGLK
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEECCCCHHHEECCCCHHHHHHHH
AAQAALADAGLVADDIDLIILATSTPDQTFPATAVTIQSELGITRGAAFDLQAVCSGFVF
HHHHHHHHCCCEECCCCEEEEEECCCCCCCCCEEEEEEHHCCCCCCCCCCHHHHHCCCEE
AIATADAHLRTGAFKRALVIGAETFSRILDWNDRGTCVLFGDGAGAIVLEGVPADEAKGR
EEEECCCHHHHCHHHHHEEECHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCCCCC
GVLTSHLRSDGRHRSKLFVDGGPSSTGTVGHLRMEGREVFKHAVGMITDVIVDAFAATGE
CHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCC
SAETIDWFVPHQANRRIIDASAQKLGIAPEKVVTTVQSHGNTSAASIPLALDVARKDGRI
CCCEEEEECCCCCCCEEEECCHHHHCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCC
KPGDLVLLEAMGGGFTWGSALLRW
CCCCEEEEEECCCCEEHHHHHHCC
>Mature Secondary Structure
MIGIHSVVRGVGSYLPQKVLTNADLAEMVDTSDEWIVQRTGIKERHVAAEGEFTSALGLK
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEECCCCHHHEECCCCHHHHHHHH
AAQAALADAGLVADDIDLIILATSTPDQTFPATAVTIQSELGITRGAAFDLQAVCSGFVF
HHHHHHHHCCCEECCCCEEEEEECCCCCCCCCEEEEEEHHCCCCCCCCCCHHHHHCCCEE
AIATADAHLRTGAFKRALVIGAETFSRILDWNDRGTCVLFGDGAGAIVLEGVPADEAKGR
EEEECCCHHHHCHHHHHEEECHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCCCCC
GVLTSHLRSDGRHRSKLFVDGGPSSTGTVGHLRMEGREVFKHAVGMITDVIVDAFAATGE
CHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCC
SAETIDWFVPHQANRRIIDASAQKLGIAPEKVVTTVQSHGNTSAASIPLALDVARKDGRI
CCCEEEEECCCCCCCEEEECCHHHHCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCC
KPGDLVLLEAMGGGFTWGSALLRW
CCCCEEEEEECCCCEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]