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The map label for this gene is 158423908

Identifier: 158423908

GI number: 158423908

Start: 2608584

End: 2609729

Strand: Direct

Name: 158423908

Synonym: AZC_2284

Alternate gene names: NA

Gene position: 2608584-2609729 (Clockwise)

Preceding gene: 158423907

Following gene: 158423909

Centisome position: 48.58

GC content: 70.42

Gene sequence:

>1146_bases
GTGAAACCGCTCGACTATAGCGGCCCCGTCGCCCCGTCCCGCCGCGCCCGATCGGGCGGAACGAAGCGGCCGCGCCCGGC
CATCGTGAAGGAGATGGCGCGGGCGGCGGGTCTCGTACTGGTGGACCAGTCAGCCCTGCGGCTCACCCGGCGCAAGGCGG
GGCGCGGCTACTGCTATTTCGATGCGTCCGGCACGCTCATCACCGACGAGCCGACGCGCGCCCGCCTCGCGTCGCTCGCC
GTTCCTCCGGCGCATAAGCAGGTGCGTTACGCGGAAAATCCCCGGGCTCATCTTCAGGCGGTCGGCTATGACGCAGCCGG
CCGCCTCCAGTATCGCTACCATCCGCGCTGGGAACTGGTGCGCGAGCGGTGCAAGGCGGAGCGCCTCGCACGCTTCGCCG
AAGCCCTGTCCACCATCCGGCGGGCGGTGGCGCGGGATCTCGGCTCACCCCCCGGTTCGCGGACCTTCGCGCTCTCGGCC
GTGGTGGAACTCGTGACCCTCACCGCCATCCGCGCCGGGGAGGAAGGCTATGCCCGAGCCCGCGGCACCCGCGGGGCGGC
GACCCTGCTGAAGTCCAATCTCCGCAGCGAGGAGGGGCAGCTCATCCTGAGTTTCCGAGCGAAGGGGGGCCGGCGAACCG
TCTGCCAGATCACCGATCCCCGTTTCATCGTGATCGTCTCGTCTCTCTCCGCCCTGCCCGGTCGGCGGCTGTTCCAGTAC
CGAGACGACGCCGGAGCCGTTCGGACCGTGCGGGCGGGCGATGTGAACGCTTATCTCAAGGAGGTCGCGGGCGTTCCGGT
CTCGCTCAAGGATTTCCGAACGCTGGTGGCTTCAGCGAGCGTCCTCGACATCCTCGCCCGTGCGGAGCCCGCGTCCAGCG
CCCGCGCGCGCAATGCGCAGGTGGTCGCGGCCATCCGAGCGGCCGCGGAGACGCTGAACAACACGCCCGCCATATGCCGC
AAGAGCTATGTGATGCCGGCCGTGGTCGCCGCCTTCGAGGACGGCACCCTGTCCCGCTTCGCCGCAACCCTGAAGCGCTG
CCGCTCGCCCATCCGCCGGGCCGGCATCCTGGCCGAACTGATCCGCGAGAGCTGCGGTGCCGGGGCGAACGTGACGCTCA
AGGACGCGCCTCGAGCCTCGCCATAA

Upstream 100 bases:

>100_bases
GCTACGCCTCCGGTGGGGAGTCGGCGCCCCTGAAGGACTGGGCGGGCAAGACCCTGCCCGCGCTGGAGCACCACCTGAAG
GTCGCGGACGACCTCAACAA

Downstream 100 bases:

>100_bases
AGGTCCGACCGAGAAAATCACAAGTCCAGCCAATGTAACGGATGACCGGAACCTGATCCACCACGGACCGTTTGCCCCAT
AGCCGTTCGGCTCATAAGAG

Product: topoisomerase IB

Products: NA

Alternate protein names: DNA poisomerase I; DNA poisomerase Type I; DNA poisomerase IB; Type I poisomerase; DNA poisomerase I Protein; Poisomerase IB; Poisomerase IB-Like Protein; DNA poisomerase I-Like Protein; Viral-Like DNA poisomerase; DNA poisomerase ; Eukaryotic-Like DNA poisomerase I; DNA poisomerasei; -Like DNA poisomerase I; Type I DNA poisomerase

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKPLDYSGPVAPSRRARSGGTKRPRPAIVKEMARAAGLVLVDQSALRLTRRKAGRGYCYFDASGTLITDEPTRARLASLA
VPPAHKQVRYAENPRAHLQAVGYDAAGRLQYRYHPRWELVRERCKAERLARFAEALSTIRRAVARDLGSPPGSRTFALSA
VVELVTLTAIRAGEEGYARARGTRGAATLLKSNLRSEEGQLILSFRAKGGRRTVCQITDPRFIVIVSSLSALPGRRLFQY
RDDAGAVRTVRAGDVNAYLKEVAGVPVSLKDFRTLVASASVLDILARAEPASSARARNAQVVAAIRAAAETLNNTPAICR
KSYVMPAVVAAFEDGTLSRFAATLKRCRSPIRRAGILAELIRESCGAGANVTLKDAPRASP

Sequences:

>Translated_381_residues
MKPLDYSGPVAPSRRARSGGTKRPRPAIVKEMARAAGLVLVDQSALRLTRRKAGRGYCYFDASGTLITDEPTRARLASLA
VPPAHKQVRYAENPRAHLQAVGYDAAGRLQYRYHPRWELVRERCKAERLARFAEALSTIRRAVARDLGSPPGSRTFALSA
VVELVTLTAIRAGEEGYARARGTRGAATLLKSNLRSEEGQLILSFRAKGGRRTVCQITDPRFIVIVSSLSALPGRRLFQY
RDDAGAVRTVRAGDVNAYLKEVAGVPVSLKDFRTLVASASVLDILARAEPASSARARNAQVVAAIRAAAETLNNTPAICR
KSYVMPAVVAAFEDGTLSRFAATLKRCRSPIRRAGILAELIRESCGAGANVTLKDAPRASP
>Mature_381_residues
MKPLDYSGPVAPSRRARSGGTKRPRPAIVKEMARAAGLVLVDQSALRLTRRKAGRGYCYFDASGTLITDEPTRARLASLA
VPPAHKQVRYAENPRAHLQAVGYDAAGRLQYRYHPRWELVRERCKAERLARFAEALSTIRRAVARDLGSPPGSRTFALSA
VVELVTLTAIRAGEEGYARARGTRGAATLLKSNLRSEEGQLILSFRAKGGRRTVCQITDPRFIVIVSSLSALPGRRLFQY
RDDAGAVRTVRAGDVNAYLKEVAGVPVSLKDFRTLVASASVLDILARAEPASSARARNAQVVAAIRAAAETLNNTPAICR
KSYVMPAVVAAFEDGTLSRFAATLKRCRSPIRRAGILAELIRESCGAGANVTLKDAPRASP

Specific function: Unknown

COG id: COG3569

COG function: function code L; Topoisomerase IB

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 5.99.1.2

Molecular weight: Translated: 41186; Mature: 41186

Theoretical pI: Translated: 11.49; Mature: 11.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLDYSGPVAPSRRARSGGTKRPRPAIVKEMARAAGLVLVDQSALRLTRRKAGRGYCYF
CCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHCCEEEECHHHHHHHHHHCCCEEEEE
DASGTLITDEPTRARLASLAVPPAHKQVRYAENPRAHLQAVGYDAAGRLQYRYHPRWELV
CCCCCEEECCCHHHHHHHHCCCCCHHHCCCCCCCHHHHHCCCCCCCCCEEEEECCHHHHH
RERCKAERLARFAEALSTIRRAVARDLGSPPGSRTFALSAVVELVTLTAIRAGEEGYARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
RGTRGAATLLKSNLRSEEGQLILSFRAKGGRRTVCQITDPRFIVIVSSLSALPGRRLFQY
CCCCHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCEEEEEEEHHHCCCCHHHHHC
RDDAGAVRTVRAGDVNAYLKEVAGVPVSLKDFRTLVASASVLDILARAEPASSARARNAQ
CCCCCCEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHH
VVAAIRAAAETLNNTPAICRKSYVMPAVVAAFEDGTLSRFAATLKRCRSPIRRAGILAEL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IRESCGAGANVTLKDAPRASP
HHHHCCCCCCEEECCCCCCCC
>Mature Secondary Structure
MKPLDYSGPVAPSRRARSGGTKRPRPAIVKEMARAAGLVLVDQSALRLTRRKAGRGYCYF
CCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHCCEEEECHHHHHHHHHHCCCEEEEE
DASGTLITDEPTRARLASLAVPPAHKQVRYAENPRAHLQAVGYDAAGRLQYRYHPRWELV
CCCCCEEECCCHHHHHHHHCCCCCHHHCCCCCCCHHHHHCCCCCCCCCEEEEECCHHHHH
RERCKAERLARFAEALSTIRRAVARDLGSPPGSRTFALSAVVELVTLTAIRAGEEGYARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
RGTRGAATLLKSNLRSEEGQLILSFRAKGGRRTVCQITDPRFIVIVSSLSALPGRRLFQY
CCCCHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCEEEEEEEHHHCCCCHHHHHC
RDDAGAVRTVRAGDVNAYLKEVAGVPVSLKDFRTLVASASVLDILARAEPASSARARNAQ
CCCCCCEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHH
VVAAIRAAAETLNNTPAICRKSYVMPAVVAAFEDGTLSRFAATLKRCRSPIRRAGILAEL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IRESCGAGANVTLKDAPRASP
HHHHCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA