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The map label for this gene is ntrB [H]

Identifier: 158423904

GI number: 158423904

Start: 2604964

End: 2606430

Strand: Direct

Name: ntrB [H]

Synonym: AZC_2280

Alternate gene names: 158423904

Gene position: 2604964-2606430 (Clockwise)

Preceding gene: 158423902

Following gene: 158423905

Centisome position: 48.51

GC content: 68.51

Gene sequence:

>1467_bases
TTGTCGAGGTCATCGGCCGAGCGGCCGTCCCAGTGCTGGATGCGCCTGCTCATGATAGGCGGCCTGTGCACCGTCATCTT
TCTCATCGACACCCTGTCGCCGATGGATATGGCCATTGCCGTGCTTTACGGCGCCGTGGTCCTTTTCGCCTCTGCCGAAC
TCGACCGCCGCGGGCTCCTTCTGGTCAGCGGAGGGTGCGTCCTCCTCACGGTCCTGAGCTTCATCATCACCCACGGCGAG
GCCTATACGCTCGCGGCGACCATGCGCGCCGTGGTGGCCATTGCCGCCATCGCCATCACCACGCTCCTCGCGCGGCGAAA
CCAGGATGCCACCGCCTCCCTGCGGGATCAGGCGGCCCTGCTCGACCTGTCGCACGATGCCATCTTCGTGCGCGACCTCG
GCGGGGTCATCACCTACTGGAGCCGGGGGGCGCATCATCTCTACGGCTGGAGCGCCTCCGAGGCGGTGGGCCTGCAAACC
GAGGCGCTGCTGCGGACGCGCTTTCCCTGCCCGCTCGACCACATCATGGCGGAGCTTGAAAGCACGGGGCAGTGGGACGG
GGAACTCGTCCACACCACCCGCGATGGCCGCAAGGTGGTGTGCCTCAGTCGCTGGTCGCTCCAGCGGGAGGCGCAAGGCC
GGCCCGCGCGCATCATGGAGACGAATCACGACATCACGGCCCGCAAGCAGGCCGAGGACGATCTCCATCAGGCGCGCAGC
GACATCGCTTATGTGACGCGCCTGAGTACGCTGGGCGAGCTCGCCACCTCCATTGCCCACGAGGTCAACCAGCCGCTCGC
CGCCATCGTGACCAATGGCGAGGCGGGCCTGCGCTGGCTGCAGCGGGACGTGCCGGATCTCGGCGAGGTCCAGCTGAGCA
TGAGCCGCATGATCTCGAACGCCCAGCGCGCGAGCAACGTCGTGGGACGCCTGCGCGCGCTGGTGCGCAGGGACGCGCCC
GACCATCTGCCGCTCGATGGCGGTGAACTGGTCGAGGACTGCCTGCTGCTGCTGGAGCGCGAGCTGGCGAACAACCGGGT
GAAGGTCTGCCCCTCCTTCCCGCCCGACCTGCCCCGGGTGCGCGGCGACCGGGTGCAGCTTCAGCAGGTGGTGATCAACC
TCGTCCTCAATGCCGCTCAGGCCATGCAGGCGGTGCCCGAGGAGGAGCGCGTGCTGCGCATCAGCGTCCACTGCGACGGG
GCGACGCCGGCCCCCTGCCTGCTCATCGAGGTGGAGGACAGCGGACCGGGCGCGCCGCCGCAGGTGCTGAACGCGCTCTT
CACCCCTTTCTTCACCACCAAGAAGGACGGCATCGGGATCGGCCTCTCCATCTCGCGCTCCATCGTGGAGGCCCATGAGG
GACGCATCCTCGCAACCCCGGCCGAGCCGCGGGGGCTGCGCATGACCGTTCAACTCCCGATCACCGGCGACATGGCAGCG
CCCGGTCTGCAGGAGAAGGCCTCGTGA

Upstream 100 bases:

>100_bases
CTACCAGAACGTGAAAGACGGGACAGGTATTGGACAAGACGGCGCCTCGCGCGCTGCTAGTTTTGATGTCTGATGCGTCA
CGCGGGGGCGGGAGAGGATA

Downstream 100 bases:

>100_bases
TGAAGGTCCAGAAATCCCGCAAGGAAACGGCGCCCGCGACACCCGTGGTGATCGTGGTGGACGACGACGCAGGTCTGCGG
GAGGCCCTGTCCAGCCTGTT

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MSRSSAERPSQCWMRLLMIGGLCTVIFLIDTLSPMDMAIAVLYGAVVLFASAELDRRGLLLVSGGCVLLTVLSFIITHGE
AYTLAATMRAVVAIAAIAITTLLARRNQDATASLRDQAALLDLSHDAIFVRDLGGVITYWSRGAHHLYGWSASEAVGLQT
EALLRTRFPCPLDHIMAELESTGQWDGELVHTTRDGRKVVCLSRWSLQREAQGRPARIMETNHDITARKQAEDDLHQARS
DIAYVTRLSTLGELATSIAHEVNQPLAAIVTNGEAGLRWLQRDVPDLGEVQLSMSRMISNAQRASNVVGRLRALVRRDAP
DHLPLDGGELVEDCLLLLERELANNRVKVCPSFPPDLPRVRGDRVQLQQVVINLVLNAAQAMQAVPEEERVLRISVHCDG
ATPAPCLLIEVEDSGPGAPPQVLNALFTPFFTTKKDGIGIGLSISRSIVEAHEGRILATPAEPRGLRMTVQLPITGDMAA
PGLQEKAS

Sequences:

>Translated_488_residues
MSRSSAERPSQCWMRLLMIGGLCTVIFLIDTLSPMDMAIAVLYGAVVLFASAELDRRGLLLVSGGCVLLTVLSFIITHGE
AYTLAATMRAVVAIAAIAITTLLARRNQDATASLRDQAALLDLSHDAIFVRDLGGVITYWSRGAHHLYGWSASEAVGLQT
EALLRTRFPCPLDHIMAELESTGQWDGELVHTTRDGRKVVCLSRWSLQREAQGRPARIMETNHDITARKQAEDDLHQARS
DIAYVTRLSTLGELATSIAHEVNQPLAAIVTNGEAGLRWLQRDVPDLGEVQLSMSRMISNAQRASNVVGRLRALVRRDAP
DHLPLDGGELVEDCLLLLERELANNRVKVCPSFPPDLPRVRGDRVQLQQVVINLVLNAAQAMQAVPEEERVLRISVHCDG
ATPAPCLLIEVEDSGPGAPPQVLNALFTPFFTTKKDGIGIGLSISRSIVEAHEGRILATPAEPRGLRMTVQLPITGDMAA
PGLQEKAS
>Mature_487_residues
SRSSAERPSQCWMRLLMIGGLCTVIFLIDTLSPMDMAIAVLYGAVVLFASAELDRRGLLLVSGGCVLLTVLSFIITHGEA
YTLAATMRAVVAIAAIAITTLLARRNQDATASLRDQAALLDLSHDAIFVRDLGGVITYWSRGAHHLYGWSASEAVGLQTE
ALLRTRFPCPLDHIMAELESTGQWDGELVHTTRDGRKVVCLSRWSLQREAQGRPARIMETNHDITARKQAEDDLHQARSD
IAYVTRLSTLGELATSIAHEVNQPLAAIVTNGEAGLRWLQRDVPDLGEVQLSMSRMISNAQRASNVVGRLRALVRRDAPD
HLPLDGGELVEDCLLLLERELANNRVKVCPSFPPDLPRVRGDRVQLQQVVINLVLNAAQAMQAVPEEERVLRISVHCDGA
TPAPCLLIEVEDSGPGAPPQVLNALFTPFFTTKKDGIGIGLSISRSIVEAHEGRILATPAEPRGLRMTVQLPITGDMAAP
GLQEKAS

Specific function: Member of the two-component regulatory system nodV/nodW probably involved in the regulation of the transcription of genes involved in the nodulation process. NodV may function as a membrane-associated protein kinase that phosphorylates nodW in response to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=233, Percent_Identity=33.4763948497854, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788549, Length=378, Percent_Identity=27.5132275132275, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1790300, Length=374, Percent_Identity=26.4705882352941, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI48994928, Length=372, Percent_Identity=25.5376344086022, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53085; Mature: 52954

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSSAERPSQCWMRLLMIGGLCTVIFLIDTLSPMDMAIAVLYGAVVLFASAELDRRGLL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEE
LVSGGCVLLTVLSFIITHGEAYTLAATMRAVVAIAAIAITTLLARRNQDATASLRDQAAL
EEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LDLSHDAIFVRDLGGVITYWSRGAHHLYGWSASEAVGLQTEALLRTRFPCPLDHIMAELE
EECCCCEEEEEHHCHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHH
STGQWDGELVHTTRDGRKVVCLSRWSLQREAQGRPARIMETNHDITARKQAEDDLHQARS
HCCCCCCEEEEEECCCCEEEEEECCCHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHH
DIAYVTRLSTLGELATSIAHEVNQPLAAIVTNGEAGLRWLQRDVPDLGEVQLSMSRMISN
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHH
AQRASNVVGRLRALVRRDAPDHLPLDGGELVEDCLLLLERELANNRVKVCPSFPPDLPRV
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCC
RGDRVQLQQVVINLVLNAAQAMQAVPEEERVLRISVHCDGATPAPCLLIEVEDSGPGAPP
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEEEEECCCCCCCH
QVLNALFTPFFTTKKDGIGIGLSISRSIVEAHEGRILATPAEPRGLRMTVQLPITGDMAA
HHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHCCEEEECCCCCCCEEEEEEEEECCCCCC
PGLQEKAS
CCCHHCCC
>Mature Secondary Structure 
SRSSAERPSQCWMRLLMIGGLCTVIFLIDTLSPMDMAIAVLYGAVVLFASAELDRRGLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEE
LVSGGCVLLTVLSFIITHGEAYTLAATMRAVVAIAAIAITTLLARRNQDATASLRDQAAL
EEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LDLSHDAIFVRDLGGVITYWSRGAHHLYGWSASEAVGLQTEALLRTRFPCPLDHIMAELE
EECCCCEEEEEHHCHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHH
STGQWDGELVHTTRDGRKVVCLSRWSLQREAQGRPARIMETNHDITARKQAEDDLHQARS
HCCCCCCEEEEEECCCCEEEEEECCCHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHH
DIAYVTRLSTLGELATSIAHEVNQPLAAIVTNGEAGLRWLQRDVPDLGEVQLSMSRMISN
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHH
AQRASNVVGRLRALVRRDAPDHLPLDGGELVEDCLLLLERELANNRVKVCPSFPPDLPRV
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCC
RGDRVQLQQVVINLVLNAAQAMQAVPEEERVLRISVHCDGATPAPCLLIEVEDSGPGAPP
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEEEEECCCCCCCH
QVLNALFTPFFTTKKDGIGIGLSISRSIVEAHEGRILATPAEPRGLRMTVQLPITGDMAA
HHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHCCEEEECCCCCCCEEEEEEEEECCCCCC
PGLQEKAS
CCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2320582; 11157954; 12597275 [H]