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The map label for this gene is lspL [H]

Identifier: 158423885

GI number: 158423885

Start: 2585020

End: 2586027

Strand: Direct

Name: lspL [H]

Synonym: AZC_2261

Alternate gene names: 158423885

Gene position: 2585020-2586027 (Clockwise)

Preceding gene: 158423884

Following gene: 158423886

Centisome position: 48.14

GC content: 65.08

Gene sequence:

>1008_bases
ATGCGTTTTCTGGTGACGGGCACGGCCGGCTTCATCGGCTTTCACCTGGCAAAGCGACTTCTGGCGGGCGGGCATGTGGT
GGTCGGCGTGGACGGCCTCACGCCCTATTATGATGTGCGCCTGAAGCACTCACGCCATGCGGAACTGGAGCGTCACAACG
GTTTCTCCGCCGTCATCGGGATGATCGAGACGCCCGACGTGCTCGCGCAGGCGGCGGATTTGGCGCAGCCGGATGTCATC
ATCCACCTCGCCGCACAGGCCGGAGTGCGTTACAGCCTCGAAAATCCGAAAGCGTATGTGGACGCCAATCTCAACGGCTC
CTGGAACGTGCTGGAACTCGCCCGGCACCTGAAGCCGCGCCATCTGCTCCTCGCATCCACCAGTTCCGTCTACGGCGCCA
ACGCCAAGGTGCCGTTCTGCGAGACCGACCGGGCCGACGAGCCCATGACGCTCTATGCGGCCACGAAGAAGTCCATGGAG
GCGATGGCGCATTCCTATGCCCATCTCTATGGCGTGCCGACCACTGCCTTCCGCTTCTTCACGGTCTATGGCCCATGGGG
CCGGCCGGACATGGCCCTGTTCAAGTTCGTCTCCGCCATCCTGAAAGGCGAGCCCATCGACATCTATGGCGAGGGCCGGA
TGTCCCGGGATTTCACCTTCATCGATGATCTGGTGGAGGCAGTCCTGCGCCTCGTGGAGCGTGCGCCCCAAACGGGCGCG
CCGGTCGGCCGCGCGGGCGTCGATTCCCTTTCGCCGGTGGCGCCGTTCCGCGTGGTGAACATCGCCGGCGGCCAGCCCGT
GGGGCTTCTCGATTTCGTCGAGACGGTAGAGCAGGCGGTCGGGCGCCCAGCCATCCGCAATTTGCTGCCGATGCAGGCCG
GCGACGTGCCCCGCACCTATGCCTCGGCCGCGCTCCTTGAGGCCCTGACCGGCTATCGTCCGGACACGCCGCTGGGCGTC
GGCGTCCCGGCCTTTGTAGAATGGTACCGGAGTTATTACGGCATCTGA

Upstream 100 bases:

>100_bases
GCGAGAGCTTGGCCTTGATGCTGCGGATCCATCAGGGCGGGGCAGGGCGCTTCGGCCTCGTGCGCGCACCGGCCGGACGG
CCGGCGGCAGTAGGTGGAAT

Downstream 100 bases:

>100_bases
CGCCGCAGTCACAGGACCGGCGGCCATGCGGTTGGGGGGTGCCTCTGCCAACCTTAGCTAAGTCGCGAGCGTGCCGTCGG
CCCCAGGCACATTAATCGCG

Product: UDP-glucuronate 5'-epimerase

Products: NA

Alternate protein names: UDP-glucuronic acid epimerase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MRFLVTGTAGFIGFHLAKRLLAGGHVVVGVDGLTPYYDVRLKHSRHAELERHNGFSAVIGMIETPDVLAQAADLAQPDVI
IHLAAQAGVRYSLENPKAYVDANLNGSWNVLELARHLKPRHLLLASTSSVYGANAKVPFCETDRADEPMTLYAATKKSME
AMAHSYAHLYGVPTTAFRFFTVYGPWGRPDMALFKFVSAILKGEPIDIYGEGRMSRDFTFIDDLVEAVLRLVERAPQTGA
PVGRAGVDSLSPVAPFRVVNIAGGQPVGLLDFVETVEQAVGRPAIRNLLPMQAGDVPRTYASAALLEALTGYRPDTPLGV
GVPAFVEWYRSYYGI

Sequences:

>Translated_335_residues
MRFLVTGTAGFIGFHLAKRLLAGGHVVVGVDGLTPYYDVRLKHSRHAELERHNGFSAVIGMIETPDVLAQAADLAQPDVI
IHLAAQAGVRYSLENPKAYVDANLNGSWNVLELARHLKPRHLLLASTSSVYGANAKVPFCETDRADEPMTLYAATKKSME
AMAHSYAHLYGVPTTAFRFFTVYGPWGRPDMALFKFVSAILKGEPIDIYGEGRMSRDFTFIDDLVEAVLRLVERAPQTGA
PVGRAGVDSLSPVAPFRVVNIAGGQPVGLLDFVETVEQAVGRPAIRNLLPMQAGDVPRTYASAALLEALTGYRPDTPLGV
GVPAFVEWYRSYYGI
>Mature_335_residues
MRFLVTGTAGFIGFHLAKRLLAGGHVVVGVDGLTPYYDVRLKHSRHAELERHNGFSAVIGMIETPDVLAQAADLAQPDVI
IHLAAQAGVRYSLENPKAYVDANLNGSWNVLELARHLKPRHLLLASTSSVYGANAKVPFCETDRADEPMTLYAATKKSME
AMAHSYAHLYGVPTTAFRFFTVYGPWGRPDMALFKFVSAILKGEPIDIYGEGRMSRDFTFIDDLVEAVLRLVERAPQTGA
PVGRAGVDSLSPVAPFRVVNIAGGQPVGLLDFVETVEQAVGRPAIRNLLPMQAGDVPRTYASAALLEALTGYRPDTPLGV
GVPAFVEWYRSYYGI

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=338, Percent_Identity=27.2189349112426, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI7657641, Length=338, Percent_Identity=24.2603550295858, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI1788353, Length=363, Percent_Identity=26.9972451790634, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786974, Length=334, Percent_Identity=24.8502994011976, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI48994969, Length=354, Percent_Identity=27.4011299435028, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788589, Length=327, Percent_Identity=25.0764525993884, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17539532, Length=245, Percent_Identity=30.6122448979592, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982038, Length=343, Percent_Identity=25.3644314868805, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71982035, Length=343, Percent_Identity=25.0728862973761, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17568069, Length=342, Percent_Identity=23.3918128654971, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21356223, Length=336, Percent_Identity=27.6785714285714, Blast_Score=107, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.12 [H]

Molecular weight: Translated: 36442; Mature: 36442

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLVTGTAGFIGFHLAKRLLAGGHVVVGVDGLTPYYDVRLKHSRHAELERHNGFSAVIG
CEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCHHHHHHCCCHHHHHC
MIETPDVLAQAADLAQPDVIIHLAAQAGVRYSLENPKAYVDANLNGSWNVLELARHLKPR
CCCCHHHHHHHHHCCCCCEEEEEECCCCCEEECCCCCEEEEECCCCCCHHHHHHHHCCCC
HLLLASTSSVYGANAKVPFCETDRADEPMTLYAATKKSMEAMAHSYAHLYGVPTTAFRFF
EEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHEEEE
TVYGPWGRPDMALFKFVSAILKGEPIDIYGEGRMSRDFTFIDDLVEAVLRLVERAPQTGA
EEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
PVGRAGVDSLSPVAPFRVVNIAGGQPVGLLDFVETVEQAVGRPAIRNLLPMQAGDVPRTY
CCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCHHH
ASAALLEALTGYRPDTPLGVGVPAFVEWYRSYYGI
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MRFLVTGTAGFIGFHLAKRLLAGGHVVVGVDGLTPYYDVRLKHSRHAELERHNGFSAVIG
CEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCHHHHHHCCCHHHHHC
MIETPDVLAQAADLAQPDVIIHLAAQAGVRYSLENPKAYVDANLNGSWNVLELARHLKPR
CCCCHHHHHHHHHCCCCCEEEEEECCCCCEEECCCCCEEEEECCCCCCHHHHHHHHCCCC
HLLLASTSSVYGANAKVPFCETDRADEPMTLYAATKKSMEAMAHSYAHLYGVPTTAFRFF
EEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHEEEE
TVYGPWGRPDMALFKFVSAILKGEPIDIYGEGRMSRDFTFIDDLVEAVLRLVERAPQTGA
EEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
PVGRAGVDSLSPVAPFRVVNIAGGQPVGLLDFVETVEQAVGRPAIRNLLPMQAGDVPRTY
CCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCHHH
ASAALLEALTGYRPDTPLGVGVPAFVEWYRSYYGI
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9765575; 11481430 [H]