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The map label for this gene is cobO [H]

Identifier: 158423881

GI number: 158423881

Start: 2580306

End: 2580926

Strand: Direct

Name: cobO [H]

Synonym: AZC_2257

Alternate gene names: 158423881

Gene position: 2580306-2580926 (Clockwise)

Preceding gene: 158423880

Following gene: 158423882

Centisome position: 48.05

GC content: 64.57

Gene sequence:

>621_bases
ATGATCAACGAACCCATCGATCCGCGCGATGCCGAGCGGCACCGGGCCAAGATGGCCAAGCGCAAGGCCGTGCAGGATGC
CGAGGTGGCGTCCAAGAATATCGAGAAGGGCCTGCTGATCGTCCACAGCGGCCCCGGCAAGGGCAAGAGCACGGCCGCCT
TCGGCCTTGCCCTGCGCATGCTGGGCTATGGGCGAACGGTTGGCATCGTGCAGTTCATCAAGGGGGCCTGGCACACGGGC
GAGAAGGATGCCTTCGCGGCCTTCGGCAATCGCGTGAAGTGGCACACCATGGGCGAGGGTTTCACCTGGGAGACGCAGGA
TCTCGCCCGTGACAAGGCGGCCGCGGAACGCGCCTTCGACAAGGCCCGTGAGCTGATGGACGACCCGGCCGTTTCGCTGG
TCATCCTCGACGAGCTGAACATCGCCTTGCGCTACGAATATCTCGACCTCAATGACGTGATTGACGTGCTGACCTCTCGC
CGGCCGGACCTGCACGTGGTCATCACCGGCCGCAACGCGAAGCCGGCGCTGATCGAGGCGGCCGATCTCGTCACCGAGAT
GCAGTTGGTGAAGCACCATTTCGCGGCCGGCGTGAAGGCGCAGGTCGGCATCGAGTTCTGA

Upstream 100 bases:

>100_bases
GGTTCCGCGATGCCGCCGGCCGTCTCAATCAGCAGTTGGCAGACAAGGCCGACCGGGTGGTGTTCCTGGTCGCCGGGCTG
CCCATGACGGTGAAAGACCA

Downstream 100 bases:

>100_bases
GCGCGTCGACAGGAGCGGGGAGGGCCATGGCGCGCGCGCTGATGTTTCAGGGCACCGGCTCGGACGTGGGCAAGTCCCTG
CTGGTCGCCGGCCTCGCCCG

Product: ATP corrinoid adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MINEPIDPRDAERHRAKMAKRKAVQDAEVASKNIEKGLLIVHSGPGKGKSTAAFGLALRMLGYGRTVGIVQFIKGAWHTG
EKDAFAAFGNRVKWHTMGEGFTWETQDLARDKAAAERAFDKARELMDDPAVSLVILDELNIALRYEYLDLNDVIDVLTSR
RPDLHVVITGRNAKPALIEAADLVTEMQLVKHHFAAGVKAQVGIEF

Sequences:

>Translated_206_residues
MINEPIDPRDAERHRAKMAKRKAVQDAEVASKNIEKGLLIVHSGPGKGKSTAAFGLALRMLGYGRTVGIVQFIKGAWHTG
EKDAFAAFGNRVKWHTMGEGFTWETQDLARDKAAAERAFDKARELMDDPAVSLVILDELNIALRYEYLDLNDVIDVLTSR
RPDLHVVITGRNAKPALIEAADLVTEMQLVKHHFAAGVKAQVGIEF
>Mature_206_residues
MINEPIDPRDAERHRAKMAKRKAVQDAEVASKNIEKGLLIVHSGPGKGKSTAAFGLALRMLGYGRTVGIVQFIKGAWHTG
EKDAFAAFGNRVKWHTMGEGFTWETQDLARDKAAAERAFDKARELMDDPAVSLVILDELNIALRYEYLDLNDVIDVLTSR
RPDLHVVITGRNAKPALIEAADLVTEMQLVKHHFAAGVKAQVGIEF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=195, Percent_Identity=43.0769230769231, Blast_Score=169, Evalue=9e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 22771; Mature: 22771

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINEPIDPRDAERHRAKMAKRKAVQDAEVASKNIEKGLLIVHSGPGKGKSTAAFGLALRM
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHH
LGYGRTVGIVQFIKGAWHTGEKDAFAAFGNRVKWHTMGEGFTWETQDLARDKAAAERAFD
HHCCCHHHHHHHHHHCCCCCCCHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
KARELMDDPAVSLVILDELNIALRYEYLDLNDVIDVLTSRRPDLHVVITGRNAKPALIEA
HHHHHHCCCCEEEEEEECCCEEEEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCHHHHH
ADLVTEMQLVKHHFAAGVKAQVGIEF
HHHHHHHHHHHHHHHCCCEEEEECCC
>Mature Secondary Structure
MINEPIDPRDAERHRAKMAKRKAVQDAEVASKNIEKGLLIVHSGPGKGKSTAAFGLALRM
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHH
LGYGRTVGIVQFIKGAWHTGEKDAFAAFGNRVKWHTMGEGFTWETQDLARDKAAAERAFD
HHCCCHHHHHHHHHHCCCCCCCHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
KARELMDDPAVSLVILDELNIALRYEYLDLNDVIDVLTSRRPDLHVVITGRNAKPALIEA
HHHHHHCCCCEEEEEEECCCEEEEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCHHHHH
ADLVTEMQLVKHHFAAGVKAQVGIEF
HHHHHHHHHHHHHHHCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]