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The map label for this gene is dppB [H]

Identifier: 158423582

GI number: 158423582

Start: 2259559

End: 2260590

Strand: Reverse

Name: dppB [H]

Synonym: AZC_1958

Alternate gene names: 158423582

Gene position: 2260590-2259559 (Counterclockwise)

Preceding gene: 158423583

Following gene: 158423581

Centisome position: 42.1

GC content: 66.67

Gene sequence:

>1032_bases
ATGAGCCAGGTCGCCCTCACGGCGCGGCGGGCGGGACGACGGTTTCTGTCGTCCCTACCGGCCCTCCTCGGCGTGCTCGT
CTTCACATTCCTTCTGATGCGCGTTCTGCCCGGCGATCCGGCGGTGTTCTTCGCCTCCGGCCCCACCGCCGGCAAGGAGG
AGATCGAAACGATCCGCAAGCAGATGGGCCTCGACAAGCCCATGCCGGAGCAGCTCGGGCGCTATCTCGTGGATGTCGCG
CAGGGCAATCTCGGGCGTTCGCTCACAACCGGCCAGCCGGTGTCGGCAGACCTTAAGGAGCGTCTGCCGGCCTCGCTGGA
ACTGACGTTTGCCGCCCTCTTCATCGCCCTCCTCTCGGCGGTGCCGCTCGGCATCGCGGCAGCGCTGCGACCCGGTTCGG
TGGTCGATCACGGCGTGCGCCTGCTCTGCGCGCTGGGCGTGTGCGTGCCCACCTTCGTGTCGGGCCTGCTGCTGATCTAT
GTCTTCTATTACCTGCTCGGCTATGCGCCTGACCCGACCGGACGCGTGGACATCTTCACCAGCCTTCCACCGCGCGCCAC
CGGCTTCCTGCTGATCGACTTCGCATTGGCCGGCGATTTCGAGGGCTGGAGGGCCGCCGCGAGCCAGCTCGTGCTGCCGG
CCTTCACCATGGCGCTCTTCGTGGTGGCCCCGCTCGCCCGCATCACCCGCGCCGCCATGCTCTCTTCGCTGGGCAGCGAT
TTCGTGCGCACGGCCCGCTCCATCGGCCTCTCCCGCTGGCGGATCATCGTCGTCTATGCGCTGCGCAACGCCATCCTGCC
CGTGCTCACCATCACCGGCATCGTCTTCTCCACCATGCTCGGCGCCAATGTGCTGGTGGAGAAGGTCTTCTCCTGGCCCG
GCGTCGCTTCCTACGCGCTCGATGCGCTGCTCGCCTCGGATTATGCGCCGGTGCAGGGCTTCGTGCTGCTGATGGCCTTC
ATCTTCGTCCTCGTGAACCTGGTGATCGACATTCTCTACGGCATCGCCGACCCCCGGATTTCGGTCGAATGA

Upstream 100 bases:

>100_bases
CGATCTGGCAGGCCTCTCAGGATGCGGTGATGGCCCCCTCCATCGAGGGCTACACCTACCAGTTCCACCGGCAGGTGGAC
TATCGCGACCTGAGCCGCAA

Downstream 100 bases:

>100_bases
GCACCGCAACCTTGCGCCATGCCGCCTTCGTGCTGCGCGGCAATCCCCTCACCGCCATCGCCGCCTTCGCGACGGGCCTG
CTCGTGCTCGTCGCCCTCTT

Product: ABC transporter permease

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MSQVALTARRAGRRFLSSLPALLGVLVFTFLLMRVLPGDPAVFFASGPTAGKEEIETIRKQMGLDKPMPEQLGRYLVDVA
QGNLGRSLTTGQPVSADLKERLPASLELTFAALFIALLSAVPLGIAAALRPGSVVDHGVRLLCALGVCVPTFVSGLLLIY
VFYYLLGYAPDPTGRVDIFTSLPPRATGFLLIDFALAGDFEGWRAAASQLVLPAFTMALFVVAPLARITRAAMLSSLGSD
FVRTARSIGLSRWRIIVVYALRNAILPVLTITGIVFSTMLGANVLVEKVFSWPGVASYALDALLASDYAPVQGFVLLMAF
IFVLVNLVIDILYGIADPRISVE

Sequences:

>Translated_343_residues
MSQVALTARRAGRRFLSSLPALLGVLVFTFLLMRVLPGDPAVFFASGPTAGKEEIETIRKQMGLDKPMPEQLGRYLVDVA
QGNLGRSLTTGQPVSADLKERLPASLELTFAALFIALLSAVPLGIAAALRPGSVVDHGVRLLCALGVCVPTFVSGLLLIY
VFYYLLGYAPDPTGRVDIFTSLPPRATGFLLIDFALAGDFEGWRAAASQLVLPAFTMALFVVAPLARITRAAMLSSLGSD
FVRTARSIGLSRWRIIVVYALRNAILPVLTITGIVFSTMLGANVLVEKVFSWPGVASYALDALLASDYAPVQGFVLLMAF
IFVLVNLVIDILYGIADPRISVE
>Mature_342_residues
SQVALTARRAGRRFLSSLPALLGVLVFTFLLMRVLPGDPAVFFASGPTAGKEEIETIRKQMGLDKPMPEQLGRYLVDVAQ
GNLGRSLTTGQPVSADLKERLPASLELTFAALFIALLSAVPLGIAAALRPGSVVDHGVRLLCALGVCVPTFVSGLLLIYV
FYYLLGYAPDPTGRVDIFTSLPPRATGFLLIDFALAGDFEGWRAAASQLVLPAFTMALFVVAPLARITRAAMLSSLGSDF
VRTARSIGLSRWRIIVVYALRNAILPVLTITGIVFSTMLGANVLVEKVFSWPGVASYALDALLASDYAPVQGFVLLMAFI
FVLVNLVIDILYGIADPRISVE

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=330, Percent_Identity=38.4848484848485, Blast_Score=232, Evalue=2e-62,
Organism=Escherichia coli, GI1787761, Length=318, Percent_Identity=42.4528301886792, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1787053, Length=328, Percent_Identity=33.5365853658537, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1789888, Length=330, Percent_Identity=34.5454545454545, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI1787497, Length=330, Percent_Identity=30.6060606060606, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1787550, Length=263, Percent_Identity=32.319391634981, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788504, Length=369, Percent_Identity=26.5582655826558, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36776; Mature: 36645

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVALTARRAGRRFLSSLPALLGVLVFTFLLMRVLPGDPAVFFASGPTAGKEEIETIRK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHH
QMGLDKPMPEQLGRYLVDVAQGNLGRSLTTGQPVSADLKERLPASLELTFAALFIALLSA
HHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHH
VPLGIAAALRPGSVVDHGVRLLCALGVCVPTFVSGLLLIYVFYYLLGYAPDPTGRVDIFT
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
SLPPRATGFLLIDFALAGDFEGWRAAASQLVLPAFTMALFVVAPLARITRAAMLSSLGSD
CCCCCCCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVRTARSIGLSRWRIIVVYALRNAILPVLTITGIVFSTMLGANVLVEKVFSWPGVASYAL
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
DALLASDYAPVQGFVLLMAFIFVLVNLVIDILYGIADPRISVE
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SQVALTARRAGRRFLSSLPALLGVLVFTFLLMRVLPGDPAVFFASGPTAGKEEIETIRK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHH
QMGLDKPMPEQLGRYLVDVAQGNLGRSLTTGQPVSADLKERLPASLELTFAALFIALLSA
HHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHH
VPLGIAAALRPGSVVDHGVRLLCALGVCVPTFVSGLLLIYVFYYLLGYAPDPTGRVDIFT
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
SLPPRATGFLLIDFALAGDFEGWRAAASQLVLPAFTMALFVVAPLARITRAAMLSSLGSD
CCCCCCCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVRTARSIGLSRWRIIVVYALRNAILPVLTITGIVFSTMLGANVLVEKVFSWPGVASYAL
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
DALLASDYAPVQGFVLLMAFIFVLVNLVIDILYGIADPRISVE
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]