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The map label for this gene is gltK [H]

Identifier: 158423549

GI number: 158423549

Start: 2227736

End: 2228428

Strand: Reverse

Name: gltK [H]

Synonym: AZC_1925

Alternate gene names: 158423549

Gene position: 2228428-2227736 (Counterclockwise)

Preceding gene: 158423550

Following gene: 158423548

Centisome position: 41.5

GC content: 64.79

Gene sequence:

>693_bases
ATGAACGGGTCCTTCGACTTCGGCGCCATCGCGGCCGCCCTGCCCTACCTGCTCGGCGACGGGCTCGGTCTCACCTTCGG
CCTCACGGTGCTTGCGGGCGCCATGGGATTCGGTCTCGGCATCCTGCTCGCCGTTCTGCGCCTCTCGCCGCTCAGGCTGC
TGTCCGTACCGGCGACGCTGTATGTCAATCTCGTGCGGTCGGTGCCGCTGGTGCTGATCATCTTCTGGTTCTACTTCCTC
GTGCCTTACATCGGCGCATGGCTCGTGGGGTCGAGCCGGCCCATCCAGGTGGGTGCCTTCCGCTCCGCCTTGGTCAGCTT
CACTTTGTTCGAGGCGGCCTATTTCTGCGAGATCATACGTGGCGGCATCCAGTCCATCCGGCGCGGCCAGATCTCCGCCG
GCCTCGCGCTGGGGCTGACCCGCCGGCAGACCTTCCTCAAGGTCGTCCTGCCGCAGGCCATCCGGAATATGACGCCGTCG
CTCCTGACGCGGCTCATCGTGCTCTTCCAGGACACATCCCTCGTTTATGTCGTCGGTCTCACCGACTTTCTCGGCGCGGC
GTCGAAAGTTGGCGCGCGGGACGGCCGCCTGACAGAGTTCTACGTCTTCGTGGCCGTCGTCTATCTCGTCATCTGTTTCG
CCGCCTCTCGTCTGGTGAAGCGCCTGGAACTGCGCTGGAAGGTGGCTCGATGA

Upstream 100 bases:

>100_bases
ACGGCTGCATCGTGCTGGCCATGCGCTGGCTCGAACGCCGCCTCGCCGTGCCCGGCCTCATCGGTGCTGCGGCCAGCAGT
CCGGCGCGGGTGGCGCAGTC

Downstream 100 bases:

>100_bases
TCTCCGCTCCTGAAAGCAGCCCGATGATCGAAATCAGGAATGTCAGCAAGTGGTACGGCCCGCATCAGGTGCTGAACGCG
TGCTCCACGCAGGTCGCCAA

Product: glutamate/aspartate transporter permease 1

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MNGSFDFGAIAAALPYLLGDGLGLTFGLTVLAGAMGFGLGILLAVLRLSPLRLLSVPATLYVNLVRSVPLVLIIFWFYFL
VPYIGAWLVGSSRPIQVGAFRSALVSFTLFEAAYFCEIIRGGIQSIRRGQISAGLALGLTRRQTFLKVVLPQAIRNMTPS
LLTRLIVLFQDTSLVYVVGLTDFLGAASKVGARDGRLTEFYVFVAVVYLVICFAASRLVKRLELRWKVAR

Sequences:

>Translated_230_residues
MNGSFDFGAIAAALPYLLGDGLGLTFGLTVLAGAMGFGLGILLAVLRLSPLRLLSVPATLYVNLVRSVPLVLIIFWFYFL
VPYIGAWLVGSSRPIQVGAFRSALVSFTLFEAAYFCEIIRGGIQSIRRGQISAGLALGLTRRQTFLKVVLPQAIRNMTPS
LLTRLIVLFQDTSLVYVVGLTDFLGAASKVGARDGRLTEFYVFVAVVYLVICFAASRLVKRLELRWKVAR
>Mature_230_residues
MNGSFDFGAIAAALPYLLGDGLGLTFGLTVLAGAMGFGLGILLAVLRLSPLRLLSVPATLYVNLVRSVPLVLIIFWFYFL
VPYIGAWLVGSSRPIQVGAFRSALVSFTLFEAAYFCEIIRGGIQSIRRGQISAGLALGLTRRQTFLKVVLPQAIRNMTPS
LLTRLIVLFQDTSLVYVVGLTDFLGAASKVGARDGRLTEFYVFVAVVYLVICFAASRLVKRLELRWKVAR

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=222, Percent_Identity=50.4504504504504, Blast_Score=194, Evalue=5e-51,
Organism=Escherichia coli, GI1787030, Length=225, Percent_Identity=32.8888888888889, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI87082239, Length=215, Percent_Identity=35.3488372093023, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI1786874, Length=197, Percent_Identity=32.994923857868, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788226, Length=213, Percent_Identity=31.924882629108, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1787087, Length=233, Percent_Identity=27.0386266094421, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1788645, Length=212, Percent_Identity=27.8301886792453, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788646, Length=196, Percent_Identity=29.0816326530612, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI48994930, Length=156, Percent_Identity=28.8461538461538, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25098; Mature: 25098

Theoretical pI: Translated: 10.98; Mature: 10.98

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGSFDFGAIAAALPYLLGDGLGLTFGLTVLAGAMGFGLGILLAVLRLSPLRLLSVPATL
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
YVNLVRSVPLVLIIFWFYFLVPYIGAWLVGSSRPIQVGAFRSALVSFTLFEAAYFCEIIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
GGIQSIRRGQISAGLALGLTRRQTFLKVVLPQAIRNMTPSLLTRLIVLFQDTSLVYVVGL
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEEH
TDFLGAASKVGARDGRLTEFYVFVAVVYLVICFAASRLVKRLELRWKVAR
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNGSFDFGAIAAALPYLLGDGLGLTFGLTVLAGAMGFGLGILLAVLRLSPLRLLSVPATL
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
YVNLVRSVPLVLIIFWFYFLVPYIGAWLVGSSRPIQVGAFRSALVSFTLFEAAYFCEIIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
GGIQSIRRGQISAGLALGLTRRQTFLKVVLPQAIRNMTPSLLTRLIVLFQDTSLVYVVGL
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEEH
TDFLGAASKVGARDGRLTEFYVFVAVVYLVICFAASRLVKRLELRWKVAR
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]