Click here to switch to the map view.

The map label for this gene is dinB1 [H]

Identifier: 158423476

GI number: 158423476

Start: 2119343

End: 2120629

Strand: Reverse

Name: dinB1 [H]

Synonym: AZC_1852

Alternate gene names: 158423476

Gene position: 2120629-2119343 (Counterclockwise)

Preceding gene: 158423477

Following gene: 158423469

Centisome position: 39.49

GC content: 68.84

Gene sequence:

>1287_bases
ATGGCCGCGCCGGGCTTCTGCCGCGACTGCCTGGCGGACGCAGGCGATGGCCCGCGCTGCACCGTCTGCGGCAGCCCGCG
CCTCGTGCGCCATCCCAAGATCCATGCCTTGAGCGTCGCCCATGTGGATTGCGACGCCTTCTATGCGGCGGTGGAGAAGC
GTGACAATCCGGCCCTGCGCGACGTGCCGGTCATCATCGGAGGCGGCACGCGGGGTGTGGTCTCCACCGCCTGCTACATC
GCCCGCATCTCCGGCGTGCGCTCGGCCATGCCCATGTTCAAGGCCCGTGCCTTGTGTCCCGATGCGGTGGTGGTGAAGCC
CAACATGGCGAAATATGCCGCCGTGGGCCGGCAGGTGCGGGGCATGATGCAGGCCTTGACCCCGCTGGTGGAGCCGCTCT
CCATCGACGAGGCCTTCCTCGACCTCACCGGCACCGAACGCCTGCACGGCATGAGCCCCGCCCGCGTGCTGGCGCGCTTC
GCGGCGCAGGTGGAGCGCGATGTGGGCATCACCATCTCGGTCGGCCTCGCCGCCAACAAGTTCCTCGCCAAGACCGCCTC
CGATCTCGACAAGCCGCGCGGTTATTCGGTGCTCGGGCTGGAAGAGGCGCCGGAGTTTCTGGCGCCCCGGCCGGTCACTT
TCATCTGGGGCGTTGGCCCCTCGTTCGGCGGCAAGCTGGCGGCGGACGGCTTCAAACTCATCGGCGACCTCCAGCGGGCG
GATGAGAAGGATCTTGCCCGCCGCTATGGCGCGGAGGGACTGCGGCTGTGGCGGCTGGCGCGGGGCATCGACGCCCGCAG
CGTAACCCCGGACCGGGAGGCGAAAAGCGTCTCCACCGAGACCACCTTCGATACCGACGTGCGCGATCTGCGCCCGCTGG
AACAGACGCTTTATGCCCTGTGCGAGAAAGTCTGCGCCCGCATGAAACAATCGGACCTCGCCGGCCGCTCGGTGACGCTG
AAGCTGAAGACGGCGGACTTCCGCCTGCGCACCCGCTCGCGCGGTCTCGACAGCCCAACCCATCTGGCCGCCCGGCTCTA
TGCCACGGCGCACGACCTGCTGCTCAAGGAAGTGGACGGCACCGCCTTCCGTCTCATCGGCGTCGGCCTCTCGGACCTCT
CGCCCGGCAGCGACGCGGATCCGGCCGATCTCGTGGACACCTCCACCCAGCGCATCAAGGCGACGGAGACAGCCATGGAT
GCGGTGCGGGCGAAATTCGGGGCCGGTGCGCTGAAGCGCGGCATCCTCTTAGACAAGCCGACGCGCAAGCCGGATGCGGG
GCGATAG

Upstream 100 bases:

>100_bases
TGCGCCCATGCCAATCTCGATCCGCAGCAGGTGGCCCGCGCCCACGATCTCCTGAGCCCGCCGGCCGATCCCGACGCGGT
GGTGCGGCGGCACTGACGCC

Downstream 100 bases:

>100_bases
GGATCAACCGACCTCGGCCACGTCCCGCACGCGCAGGCTGACGCGGGCCTCGCCCTGCCAGTGGTCCATGTCGAGGCCGC
CGGCCACGTGCAGGTTGCGG

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV 1 [H]

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MAAPGFCRDCLADAGDGPRCTVCGSPRLVRHPKIHALSVAHVDCDAFYAAVEKRDNPALRDVPVIIGGGTRGVVSTACYI
ARISGVRSAMPMFKARALCPDAVVVKPNMAKYAAVGRQVRGMMQALTPLVEPLSIDEAFLDLTGTERLHGMSPARVLARF
AAQVERDVGITISVGLAANKFLAKTASDLDKPRGYSVLGLEEAPEFLAPRPVTFIWGVGPSFGGKLAADGFKLIGDLQRA
DEKDLARRYGAEGLRLWRLARGIDARSVTPDREAKSVSTETTFDTDVRDLRPLEQTLYALCEKVCARMKQSDLAGRSVTL
KLKTADFRLRTRSRGLDSPTHLAARLYATAHDLLLKEVDGTAFRLIGVGLSDLSPGSDADPADLVDTSTQRIKATETAMD
AVRAKFGAGALKRGILLDKPTRKPDAGR

Sequences:

>Translated_428_residues
MAAPGFCRDCLADAGDGPRCTVCGSPRLVRHPKIHALSVAHVDCDAFYAAVEKRDNPALRDVPVIIGGGTRGVVSTACYI
ARISGVRSAMPMFKARALCPDAVVVKPNMAKYAAVGRQVRGMMQALTPLVEPLSIDEAFLDLTGTERLHGMSPARVLARF
AAQVERDVGITISVGLAANKFLAKTASDLDKPRGYSVLGLEEAPEFLAPRPVTFIWGVGPSFGGKLAADGFKLIGDLQRA
DEKDLARRYGAEGLRLWRLARGIDARSVTPDREAKSVSTETTFDTDVRDLRPLEQTLYALCEKVCARMKQSDLAGRSVTL
KLKTADFRLRTRSRGLDSPTHLAARLYATAHDLLLKEVDGTAFRLIGVGLSDLSPGSDADPADLVDTSTQRIKATETAMD
AVRAKFGAGALKRGILLDKPTRKPDAGR
>Mature_427_residues
AAPGFCRDCLADAGDGPRCTVCGSPRLVRHPKIHALSVAHVDCDAFYAAVEKRDNPALRDVPVIIGGGTRGVVSTACYIA
RISGVRSAMPMFKARALCPDAVVVKPNMAKYAAVGRQVRGMMQALTPLVEPLSIDEAFLDLTGTERLHGMSPARVLARFA
AQVERDVGITISVGLAANKFLAKTASDLDKPRGYSVLGLEEAPEFLAPRPVTFIWGVGPSFGGKLAADGFKLIGDLQRAD
EKDLARRYGAEGLRLWRLARGIDARSVTPDREAKSVSTETTFDTDVRDLRPLEQTLYALCEKVCARMKQSDLAGRSVTLK
LKTADFRLRTRSRGLDSPTHLAARLYATAHDLLLKEVDGTAFRLIGVGLSDLSPGSDADPADLVDTSTQRIKATETAMDA
VRAKFGAGALKRGILLDKPTRKPDAGR

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=366, Percent_Identity=26.5027322404372, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI7706681, Length=254, Percent_Identity=29.9212598425197, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI7705344, Length=175, Percent_Identity=36.5714285714286, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI154350220, Length=369, Percent_Identity=26.2872628726287, Blast_Score=105, Evalue=1e-22,
Organism=Escherichia coli, GI1786425, Length=342, Percent_Identity=39.1812865497076, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1787432, Length=392, Percent_Identity=26.7857142857143, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI193205700, Length=391, Percent_Identity=30.690537084399, Blast_Score=130, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI193205702, Length=343, Percent_Identity=28.2798833819242, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17537959, Length=302, Percent_Identity=24.5033112582781, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19923006, Length=335, Percent_Identity=24.7761194029851, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21355641, Length=283, Percent_Identity=27.9151943462898, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24644984, Length=283, Percent_Identity=27.9151943462898, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24668444, Length=161, Percent_Identity=31.055900621118, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 46025; Mature: 45893

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPGFCRDCLADAGDGPRCTVCGSPRLVRHPKIHALSVAHVDCDAFYAAVEKRDNPALR
CCCCCHHHHHHHCCCCCCEEEECCCCCEECCCCEEEEEEEEECHHHHHHHHHCCCCCCCC
DVPVIIGGGTRGVVSTACYIARISGVRSAMPMFKARALCPDAVVVKPNMAKYAAVGRQVR
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHH
GMMQALTPLVEPLSIDEAFLDLTGTERLHGMSPARVLARFAAQVERDVGITISVGLAANK
HHHHHHHHHHCCCCCCHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHH
FLAKTASDLDKPRGYSVLGLEEAPEFLAPRPVTFIWGVGPSFGGKLAADGFKLIGDLQRA
HHHHHHHHHCCCCCCEEEEHHHCCHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHC
DEKDLARRYGAEGLRLWRLARGIDARSVTPDREAKSVSTETTFDTDVRDLRPLEQTLYAL
CHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
CEKVCARMKQSDLAGRSVTLKLKTADFRLRTRSRGLDSPTHLAARLYATAHDLLLKEVDG
HHHHHHHHHHHCCCCCEEEEEEEECCEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
TAFRLIGVGLSDLSPGSDADPADLVDTSTQRIKATETAMDAVRAKFGAGALKRGILLDKP
CEEEEEECCHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCEECCC
TRKPDAGR
CCCCCCCC
>Mature Secondary Structure 
AAPGFCRDCLADAGDGPRCTVCGSPRLVRHPKIHALSVAHVDCDAFYAAVEKRDNPALR
CCCCHHHHHHHCCCCCCEEEECCCCCEECCCCEEEEEEEEECHHHHHHHHHCCCCCCCC
DVPVIIGGGTRGVVSTACYIARISGVRSAMPMFKARALCPDAVVVKPNMAKYAAVGRQVR
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHH
GMMQALTPLVEPLSIDEAFLDLTGTERLHGMSPARVLARFAAQVERDVGITISVGLAANK
HHHHHHHHHHCCCCCCHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHH
FLAKTASDLDKPRGYSVLGLEEAPEFLAPRPVTFIWGVGPSFGGKLAADGFKLIGDLQRA
HHHHHHHHHCCCCCCEEEEHHHCCHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHC
DEKDLARRYGAEGLRLWRLARGIDARSVTPDREAKSVSTETTFDTDVRDLRPLEQTLYAL
CHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
CEKVCARMKQSDLAGRSVTLKLKTADFRLRTRSRGLDSPTHLAARLYATAHDLLLKEVDG
HHHHHHHHHHHCCCCCEEEEEEEECCEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
TAFRLIGVGLSDLSPGSDADPADLVDTSTQRIKATETAMDAVRAKFGAGALKRGILLDKP
CEEEEEECCHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCEECCC
TRKPDAGR
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]