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The map label for this gene is gltA [H]

Identifier: 158423334

GI number: 158423334

Start: 1956920

End: 1958224

Strand: Reverse

Name: gltA [H]

Synonym: AZC_1710

Alternate gene names: 158423334

Gene position: 1958224-1956920 (Counterclockwise)

Preceding gene: 158423335

Following gene: 158423331

Centisome position: 36.47

GC content: 63.37

Gene sequence:

>1305_bases
ATGGACGCCACCAACAACGCCACCGCGGCCAAGCTGACAGTGGGCGACAAGAGCTGGGAATTCCCCATCAAGAAAGGAAC
CATCGGGCCTGACGTGGTGGATATCTCCAAGCTCTACGGCCAGAGCGGGATGTTCACCTACGATCCGGGCTTCACGTCCA
CCGCGTCCTGCGAGAGCCAGATCACCTATATCGACGGCGACGAAGGCGTTCTCCTCTATCGCGGCTTCCCCATCGAGCAG
CTCGCCGAGGGCGGTGACTTCCTCGAGACCTGCTACCTGCTGCTGTACGGCGAACTGCCGACCGCCGCCCAGAAGGCGGA
CTTCGATCACTCCGTGACCCGTCACACGATGGTTCACGACCAGATGAACCGCTTCTTCAACGGCTTCCGCCGCGACGCGC
ACCCCATGGCGATCATGGTGGCCTGCGTCGGCGCGCTCTCGGCCTTCTATCACGACTCCACCGACATCTCCGATCCGCAG
CAGCGCCTCATCGCGTCCATCCGCATGATCGCGAAGATGCCGACGCTGGCGGCGATGGCTTACAAGTATTCGATCGGTCA
GCCCTTCGTGTATCCGAAGAACGACCTCGACTACGCCTCCAACTTCCTCAACATGTGCTTCGCGGTCCCCTGCGAGGATT
ACAAGGTGAGCCCGACGCTCGCCCGTGCGCTGGACAAGATCTTCATCCTGCACGCGGACCACGAGCAGAACGCTTCCACC
TCGACGGTGCGTCTCGCCGGCTCGTCCGGCGCCAACCCGTTCGCCTGTATCGCCGCCGGCATCGCCTGCCTGTGGGGTCC
GGCGCACGGCGGCGCCAATGAAGCCGCCCTCAAGATGCTGACCGAGATCGGCACGCCGGACCGCATCCCCGAGTTCGTGA
ACAAGGCGAAGGACAAGAACGATCCCTTCCGCCTCATGGGCTTCGGCCACCGGGTCTACAAGAACTACGACCCGCGCGCC
AAGATCATGCAGCAGACCTGCCACGAAGTGCTGACCGAGCTCGGCATCAAGGACGATCCGCTGCTCGACGTGGCGGTGGA
ACTCGAGCGCGTCGCCCTGCACGACGAGTACTTCATCGAGAAGAAGCTCTATCCGAACATCGACTTCTATTCGGGCATCA
CCCTGAAGGCGATGGGCTTCCCCACCACCATGTTCACCGTGCTGTTCGCCCTCGCGCGGACCGTCGGCTGGATCGGCCAG
TGGAAGGAAATGATCGAGGACCCGAGCCAGCGCATCGGCCGTCCCCGCCAGCTCTACACCGGCGCCGCCCGCCGCGATTA
CGTGGCGATGTCCAAGCGCAAGTGA

Upstream 100 bases:

>100_bases
CACGCTTGCGGCGGATTTAGGGAGGGTTTACGACTGCGCCCCGGATGCCTTCGCACCCGCGAAGCGCTCAGCGCTTCCGC
CCGATTTCAAGGGAGATCTC

Downstream 100 bases:

>100_bases
GCGGGACGCGGGGGCCTGCCCCCCGCTGCCCAGCCTTTCTAGGGCGCGGCTTCGGCCGCGCCCTTTTTTTTGTGCCGGCG
GAGCCTCTATCGGTGAAGGA

Product: citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MDATNNATAAKLTVGDKSWEFPIKKGTIGPDVVDISKLYGQSGMFTYDPGFTSTASCESQITYIDGDEGVLLYRGFPIEQ
LAEGGDFLETCYLLLYGELPTAAQKADFDHSVTRHTMVHDQMNRFFNGFRRDAHPMAIMVACVGALSAFYHDSTDISDPQ
QRLIASIRMIAKMPTLAAMAYKYSIGQPFVYPKNDLDYASNFLNMCFAVPCEDYKVSPTLARALDKIFILHADHEQNAST
STVRLAGSSGANPFACIAAGIACLWGPAHGGANEAALKMLTEIGTPDRIPEFVNKAKDKNDPFRLMGFGHRVYKNYDPRA
KIMQQTCHEVLTELGIKDDPLLDVAVELERVALHDEYFIEKKLYPNIDFYSGITLKAMGFPTTMFTVLFALARTVGWIGQ
WKEMIEDPSQRIGRPRQLYTGAARRDYVAMSKRK

Sequences:

>Translated_434_residues
MDATNNATAAKLTVGDKSWEFPIKKGTIGPDVVDISKLYGQSGMFTYDPGFTSTASCESQITYIDGDEGVLLYRGFPIEQ
LAEGGDFLETCYLLLYGELPTAAQKADFDHSVTRHTMVHDQMNRFFNGFRRDAHPMAIMVACVGALSAFYHDSTDISDPQ
QRLIASIRMIAKMPTLAAMAYKYSIGQPFVYPKNDLDYASNFLNMCFAVPCEDYKVSPTLARALDKIFILHADHEQNAST
STVRLAGSSGANPFACIAAGIACLWGPAHGGANEAALKMLTEIGTPDRIPEFVNKAKDKNDPFRLMGFGHRVYKNYDPRA
KIMQQTCHEVLTELGIKDDPLLDVAVELERVALHDEYFIEKKLYPNIDFYSGITLKAMGFPTTMFTVLFALARTVGWIGQ
WKEMIEDPSQRIGRPRQLYTGAARRDYVAMSKRK
>Mature_434_residues
MDATNNATAAKLTVGDKSWEFPIKKGTIGPDVVDISKLYGQSGMFTYDPGFTSTASCESQITYIDGDEGVLLYRGFPIEQ
LAEGGDFLETCYLLLYGELPTAAQKADFDHSVTRHTMVHDQMNRFFNGFRRDAHPMAIMVACVGALSAFYHDSTDISDPQ
QRLIASIRMIAKMPTLAAMAYKYSIGQPFVYPKNDLDYASNFLNMCFAVPCEDYKVSPTLARALDKIFILHADHEQNAST
STVRLAGSSGANPFACIAAGIACLWGPAHGGANEAALKMLTEIGTPDRIPEFVNKAKDKNDPFRLMGFGHRVYKNYDPRA
KIMQQTCHEVLTELGIKDDPLLDVAVELERVALHDEYFIEKKLYPNIDFYSGITLKAMGFPTTMFTVLFALARTVGWIGQ
WKEMIEDPSQRIGRPRQLYTGAARRDYVAMSKRK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=393, Percent_Identity=26.972010178117, Blast_Score=112, Evalue=7e-25,
Organism=Escherichia coli, GI1786939, Length=427, Percent_Identity=68.8524590163934, Blast_Score=629, Evalue=0.0,
Organism=Escherichia coli, GI1786527, Length=365, Percent_Identity=30.4109589041096, Blast_Score=162, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI17555174, Length=422, Percent_Identity=26.5402843601896, Blast_Score=117, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6319850, Length=352, Percent_Identity=26.9886363636364, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6325257, Length=415, Percent_Identity=25.5421686746988, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324328, Length=330, Percent_Identity=26.0606060606061, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24640126, Length=402, Percent_Identity=27.363184079602, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24640124, Length=402, Percent_Identity=27.363184079602, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21356863, Length=429, Percent_Identity=24.4755244755245, Blast_Score=99, Evalue=7e-21,

Paralogues:

None

Copy number: 624 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810
- InterPro:   IPR010953 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 48341; Mature: 48341

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00480 CITRATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDATNNATAAKLTVGDKSWEFPIKKGTIGPDVVDISKLYGQSGMFTYDPGFTSTASCESQ
CCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECCCCCCCCCCCCE
ITYIDGDEGVLLYRGFPIEQLAEGGDFLETCYLLLYGELPTAAQKADFDHSVTRHTMVHD
EEEEECCCCEEEEECCCHHHHHCCCCHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHH
QMNRFFNGFRRDAHPMAIMVACVGALSAFYHDSTDISDPQQRLIASIRMIAKMPTLAAMA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
YKYSIGQPFVYPKNDLDYASNFLNMCFAVPCEDYKVSPTLARALDKIFILHADHEQNAST
HHHCCCCCCCCCCCCHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHEEEEECCCCCCCCC
STVRLAGSSGANPFACIAAGIACLWGPAHGGANEAALKMLTEIGTPDRIPEFVNKAKDKN
CEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCC
DPFRLMGFGHRVYKNYDPRAKIMQQTCHEVLTELGIKDDPLLDVAVELERVALHDEYFIE
CCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
KKLYPNIDFYSGITLKAMGFPTTMFTVLFALARTVGWIGQWKEMIEDPSQRIGRPRQLYT
HHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHH
GAARRDYVAMSKRK
CCHHHHHHHHCCCC
>Mature Secondary Structure
MDATNNATAAKLTVGDKSWEFPIKKGTIGPDVVDISKLYGQSGMFTYDPGFTSTASCESQ
CCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECCCCCCCCCCCCE
ITYIDGDEGVLLYRGFPIEQLAEGGDFLETCYLLLYGELPTAAQKADFDHSVTRHTMVHD
EEEEECCCCEEEEECCCHHHHHCCCCHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHH
QMNRFFNGFRRDAHPMAIMVACVGALSAFYHDSTDISDPQQRLIASIRMIAKMPTLAAMA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
YKYSIGQPFVYPKNDLDYASNFLNMCFAVPCEDYKVSPTLARALDKIFILHADHEQNAST
HHHCCCCCCCCCCCCHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHEEEEECCCCCCCCC
STVRLAGSSGANPFACIAAGIACLWGPAHGGANEAALKMLTEIGTPDRIPEFVNKAKDKN
CEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCC
DPFRLMGFGHRVYKNYDPRAKIMQQTCHEVLTELGIKDDPLLDVAVELERVALHDEYFIE
CCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
KKLYPNIDFYSGITLKAMGFPTTMFTVLFALARTVGWIGQWKEMIEDPSQRIGRPRQLYT
HHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHH
GAARRDYVAMSKRK
CCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8526514 [H]