Click here to switch to the map view.

The map label for this gene is yafC [H]

Identifier: 158423331

GI number: 158423331

Start: 1954674

End: 1955612

Strand: Reverse

Name: yafC [H]

Synonym: AZC_1707

Alternate gene names: 158423331

Gene position: 1955612-1954674 (Counterclockwise)

Preceding gene: 158423334

Following gene: 158423316

Centisome position: 36.42

GC content: 69.54

Gene sequence:

>939_bases
ATGTGGCACGTATCGTTCCACATGAGGAACGATGTCATGGCGGATCTCAACGACTACGCCTTCTTTGCCGAGGTGGTGAG
GCACGGCGGCTTCGCCCCCGCCGGCAGGGCGCTTCATACCCCCAAGTCCAAGCTCAGCCGCCGGGTGGCGGCGCTGGAGG
CGCGGCTCGGCGTCCGCCTCATCGAGCGCTCCTCCCGGCGCTTTCGGGTGACGGAGGTGGGGGAGGCCTTCTATGGACGC
TGCCGGGCGCTGCTGGAGGAAGCGGAGCAGGCGGAAGCGCTGGTCGCGCAGGCGCGGAGCGAACCTCGCGGGCTCGTCCG
CTTCAGTTGCCCCACGGGCCTTGTGGAAGTGCTGTCGCCCGGCCTCCCCGCCTTCCTGTCCCGCCATCCCAAGGTCCGGA
TGCAGTTGATCGCGGCAGACCGGCCGGTGGATCTCATCGCCGAGCGCATCGACGTGGCCCTGCGGGTGCGGGTGGACCTC
ACCACCGACGCCTCACTCACCATGCGCACGCTGGGCCGCTCACGCCGCATTCTCGTCGCCGCCCCGGCACTTGCGGGAAG
GGTGCCGGGTGCCGACATCGCGAGCCTGAACGACCTGCCGACGCTGGGTTCCAACGATGAAATCGGCGAGACGGTCTGGG
ATCTCGTGGGTCCGGATGGCGCCAGCCACAGCCTGCGGCACGAGCCGCGCCTCAGCTGCGTGGACTTTGCCGCGCTGCGC
GAGGCGGCAGCCGCCGGTCTCGGCGTTGCCCTTCTGCCCGATCACATCTGCCGTACCGACCTTGCCAGCGGCCGGCTGGT
CAGGGTCTTTCCGGGCTGGGGCGGGCAGATGGGCATCGTGCACATCGTCTTTACAACGCGCCGGGGCCTGACGCCCGCCG
TGCGCGCGCTCATCGACCACCTCGCCGCCACCTTCAACCGGCTGAAACTGGACGAGTGA

Upstream 100 bases:

>100_bases
ACGTCGTCATGATCCTGTCTCCTGTCGATGGTTGCGGCGGCTGAGGCCGTCGCTGATGGACAAGAGTTAGATCCGGAACG
CTGATGCCTGTAGCCGCCAG

Downstream 100 bases:

>100_bases
AGCTCAGTGCCGGCGCGCAGCCGCTGCCTCGAGCACTACAGCCGCCGCCCGCTGGGAGGGCGGGGCGTCGTCGGCACCCA
TGATGGTGTCGAGCTTCGCG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MWHVSFHMRNDVMADLNDYAFFAEVVRHGGFAPAGRALHTPKSKLSRRVAALEARLGVRLIERSSRRFRVTEVGEAFYGR
CRALLEEAEQAEALVAQARSEPRGLVRFSCPTGLVEVLSPGLPAFLSRHPKVRMQLIAADRPVDLIAERIDVALRVRVDL
TTDASLTMRTLGRSRRILVAAPALAGRVPGADIASLNDLPTLGSNDEIGETVWDLVGPDGASHSLRHEPRLSCVDFAALR
EAAAAGLGVALLPDHICRTDLASGRLVRVFPGWGGQMGIVHIVFTTRRGLTPAVRALIDHLAATFNRLKLDE

Sequences:

>Translated_312_residues
MWHVSFHMRNDVMADLNDYAFFAEVVRHGGFAPAGRALHTPKSKLSRRVAALEARLGVRLIERSSRRFRVTEVGEAFYGR
CRALLEEAEQAEALVAQARSEPRGLVRFSCPTGLVEVLSPGLPAFLSRHPKVRMQLIAADRPVDLIAERIDVALRVRVDL
TTDASLTMRTLGRSRRILVAAPALAGRVPGADIASLNDLPTLGSNDEIGETVWDLVGPDGASHSLRHEPRLSCVDFAALR
EAAAAGLGVALLPDHICRTDLASGRLVRVFPGWGGQMGIVHIVFTTRRGLTPAVRALIDHLAATFNRLKLDE
>Mature_312_residues
MWHVSFHMRNDVMADLNDYAFFAEVVRHGGFAPAGRALHTPKSKLSRRVAALEARLGVRLIERSSRRFRVTEVGEAFYGR
CRALLEEAEQAEALVAQARSEPRGLVRFSCPTGLVEVLSPGLPAFLSRHPKVRMQLIAADRPVDLIAERIDVALRVRVDL
TTDASLTMRTLGRSRRILVAAPALAGRVPGADIASLNDLPTLGSNDEIGETVWDLVGPDGASHSLRHEPRLSCVDFAALR
EAAAAGLGVALLPDHICRTDLASGRLVRVFPGWGGQMGIVHIVFTTRRGLTPAVRALIDHLAATFNRLKLDE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=292, Percent_Identity=30.4794520547945, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1789639, Length=299, Percent_Identity=28.4280936454849, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=29.3515358361775, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI145693193, Length=302, Percent_Identity=26.8211920529801, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789440, Length=292, Percent_Identity=24.6575342465753, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1787589, Length=304, Percent_Identity=26.3157894736842, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787128, Length=297, Percent_Identity=22.8956228956229, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788706, Length=293, Percent_Identity=27.6450511945392, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789173, Length=258, Percent_Identity=25.968992248062, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI157672245, Length=138, Percent_Identity=28.9855072463768, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34049; Mature: 34049

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWHVSFHMRNDVMADLNDYAFFAEVVRHGGFAPAGRALHTPKSKLSRRVAALEARLGVRL
CEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
IERSSRRFRVTEVGEAFYGRCRALLEEAEQAEALVAQARSEPRGLVRFSCPTGLVEVLSP
HHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHCC
GLPAFLSRHPKVRMQLIAADRPVDLIAERIDVALRVRVDLTTDASLTMRTLGRSRRILVA
CCHHHHCCCCCEEEEEEECCCCHHHHHHHHCEEEEEEEEECCCCHHHHHHHCCCCEEEEE
APALAGRVPGADIASLNDLPTLGSNDEIGETVWDLVGPDGASHSLRHEPRLSCVDFAALR
CCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
EAAAAGLGVALLPDHICRTDLASGRLVRVFPGWGGQMGIVHIVFTTRRGLTPAVRALIDH
HHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHH
LAATFNRLKLDE
HHHHHHHHCCCC
>Mature Secondary Structure
MWHVSFHMRNDVMADLNDYAFFAEVVRHGGFAPAGRALHTPKSKLSRRVAALEARLGVRL
CEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
IERSSRRFRVTEVGEAFYGRCRALLEEAEQAEALVAQARSEPRGLVRFSCPTGLVEVLSP
HHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHCC
GLPAFLSRHPKVRMQLIAADRPVDLIAERIDVALRVRVDLTTDASLTMRTLGRSRRILVA
CCHHHHCCCCCEEEEEEECCCCHHHHHHHHCEEEEEEEEECCCCHHHHHHHCCCCEEEEE
APALAGRVPGADIASLNDLPTLGSNDEIGETVWDLVGPDGASHSLRHEPRLSCVDFAALR
CCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
EAAAAGLGVALLPDHICRTDLASGRLVRVFPGWGGQMGIVHIVFTTRRGLTPAVRALIDH
HHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHH
LAATFNRLKLDE
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]