Click here to switch to the map view.

The map label for this gene is 158423307

Identifier: 158423307

GI number: 158423307

Start: 1925139

End: 1926806

Strand: Direct

Name: 158423307

Synonym: AZC_1683

Alternate gene names: NA

Gene position: 1925139-1926806 (Clockwise)

Preceding gene: 158423306

Following gene: 158423308

Centisome position: 35.85

GC content: 68.71

Gene sequence:

>1668_bases
ATGGCTGACAACAACGAGCTCGTCTTCGCGCCTCTCGGGGGGGTGGGCGAGATCGGCATGAATCTCGGCCTCTACGGGAT
CGGACCGCGCAAGCAGCGCCAGTGGCTCATCGTCGATCTCGGCATGAGCTTCGCGGGCGAGGAGGCGCCGGGCGTCGATC
TCGTCATGCCTGACATCCGTTTCCTGGAGAGCGTCAAGGATCGCATTGCCGGTCTCGTGCTGACCCATGGACACGAGGAC
CATGTGGGCGCCATGCTGGACCTGTGGCCCCGCATCGGCTGCCCGGTCTATACGACCCGCTTCACCGCCGCTTTGCTGGA
CGCCAAGCGCCTGCAGGAGCCCGGCGCGCCGAAGATCCCGATCGAGGTGGTCCGCTCCGGCGGTCGGGCCCAGATCGGTC
CCTTCGAGGTGGAGTTCGTGCCTGTCGCGCACTCCATCCCCGACAGCCACGCCCTCGCCATCCGCACCGCCGCCGGCCTC
GTGCTGCACACCGGCGACTGGAAGCTCGACCCGACCCCCGTGGTGGGCCATGTGACGGACATTGCCCGCCTCCAGGCCCT
CGGCGACGAGGGCGTGCGGGCGATGATCTGCGATTCCACCAACGCCATCCGCGACGGCGTCTCGCCATCCGAGGCGGACG
TGGCGGCGACGCTGCGGGACGTGGTCGCCAAGGCGAAGTATCGCGTCGCCTTCACCACCTTCTCCTCCAACGTCGCCCGC
GTGCGCGCCATCGCGGAAGCCGCCTATGCCAATGACCGCGAGGTGGTGGTGGTGGGCCGCGCCATGGAGCGCGTCATCGG
GGTTGCCCGCGAGCAGGGCATGCTGGACGGCCTGCCGGCCTTCCGGGGTGCCGATGCCTTCGGCTTCCTGCCCCGCGACA
AGGTGGTGGCCATCCTCACCGGCAGCCAGGGCGAGCCGCGCGCCGCGCTGAGCCGCATCGCCACCGACGACCATCCGGAG
ATCGCCCTGTCCCATGGCGACCTCGTGGTCTTCTCCTCACGCACCATTCCCGGCAACGAGAAGGTGGTGAACACGGTCAT
CAACGGCCTCGTGAAGCGGGGCATCAAGGTGATGACCGACAAGGACGGCCTCGTCCACGTCTCCGGCCATCCGCGGCGCG
GCGAACTGGAGCAGATGTACAAGTGGGTGCGCCCGCAGGTTTCCGTGCCGGTGCATGGCGAGCCGCTGCATCTGACCGAG
CATGCCGCGCTCGCCAAGGCGCTCGGCGTTCCGGAGGTGGTCTCCTGCGCCGACGGCCATGTGATCCGCCTCGCGCCCGG
CCATGCCGAACGGGTGGAGGACGTGCCTTACGGGCGCCTCTACAAGGACGGCCGCCTGCTGATCCCCGACAGCGCTCGTA
CGATTCCCGAGCGCCGGCGCCTCGCTTATGTGGGCATCGTCTCGGTGGCGCTCGCCGTGGACAATCGCGGCAACCTCGTG
GGCGATCCCTCGGTGGAGATCACCGGCATTCCCGAGCGGGGGGAGGGGGGCATCGATTTCCTCGACCTCATCCTCGATAC
GGTGGTGACCACCGCCGAGGGCCTGCCCAAGGCGCGGCGTCGCGATCCCGATGCCATGTCCGATTCCATCGAGCGGGCCG
TGCGCGGGGCGGTCAATGGCGCGTGGGGCAAAAAGCCGGTTTGCCACGTCCATATCGTCGAGGTTTGA

Upstream 100 bases:

>100_bases
ATAATCGCGGCGCGATGATGTTGCGCCGCCGGGATGGCATCGCCGAAATCGTTACGGCGGGCGAGGTCTCCCTCACACCG
AAAGTGGATTGAACCATCTG

Downstream 100 bases:

>100_bases
TAGGCCCCATAATGCGCGTGCGCCGTGCGGGCGCCGCCACTGTGGGGAGACATGGGCATGATCGGACGCCTCAATCACGT
GGCCATCGCGGTCAAGGACA

Product: metallo-beta-lactamase family hydrolase

Products: NA

Alternate protein names: RNase J [H]

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MADNNELVFAPLGGVGEIGMNLGLYGIGPRKQRQWLIVDLGMSFAGEEAPGVDLVMPDIRFLESVKDRIAGLVLTHGHED
HVGAMLDLWPRIGCPVYTTRFTAALLDAKRLQEPGAPKIPIEVVRSGGRAQIGPFEVEFVPVAHSIPDSHALAIRTAAGL
VLHTGDWKLDPTPVVGHVTDIARLQALGDEGVRAMICDSTNAIRDGVSPSEADVAATLRDVVAKAKYRVAFTTFSSNVAR
VRAIAEAAYANDREVVVVGRAMERVIGVAREQGMLDGLPAFRGADAFGFLPRDKVVAILTGSQGEPRAALSRIATDDHPE
IALSHGDLVVFSSRTIPGNEKVVNTVINGLVKRGIKVMTDKDGLVHVSGHPRRGELEQMYKWVRPQVSVPVHGEPLHLTE
HAALAKALGVPEVVSCADGHVIRLAPGHAERVEDVPYGRLYKDGRLLIPDSARTIPERRRLAYVGIVSVALAVDNRGNLV
GDPSVEITGIPERGEGGIDFLDLILDTVVTTAEGLPKARRRDPDAMSDSIERAVRGAVNGAWGKKPVCHVHIVEV

Sequences:

>Translated_555_residues
MADNNELVFAPLGGVGEIGMNLGLYGIGPRKQRQWLIVDLGMSFAGEEAPGVDLVMPDIRFLESVKDRIAGLVLTHGHED
HVGAMLDLWPRIGCPVYTTRFTAALLDAKRLQEPGAPKIPIEVVRSGGRAQIGPFEVEFVPVAHSIPDSHALAIRTAAGL
VLHTGDWKLDPTPVVGHVTDIARLQALGDEGVRAMICDSTNAIRDGVSPSEADVAATLRDVVAKAKYRVAFTTFSSNVAR
VRAIAEAAYANDREVVVVGRAMERVIGVAREQGMLDGLPAFRGADAFGFLPRDKVVAILTGSQGEPRAALSRIATDDHPE
IALSHGDLVVFSSRTIPGNEKVVNTVINGLVKRGIKVMTDKDGLVHVSGHPRRGELEQMYKWVRPQVSVPVHGEPLHLTE
HAALAKALGVPEVVSCADGHVIRLAPGHAERVEDVPYGRLYKDGRLLIPDSARTIPERRRLAYVGIVSVALAVDNRGNLV
GDPSVEITGIPERGEGGIDFLDLILDTVVTTAEGLPKARRRDPDAMSDSIERAVRGAVNGAWGKKPVCHVHIVEV
>Mature_554_residues
ADNNELVFAPLGGVGEIGMNLGLYGIGPRKQRQWLIVDLGMSFAGEEAPGVDLVMPDIRFLESVKDRIAGLVLTHGHEDH
VGAMLDLWPRIGCPVYTTRFTAALLDAKRLQEPGAPKIPIEVVRSGGRAQIGPFEVEFVPVAHSIPDSHALAIRTAAGLV
LHTGDWKLDPTPVVGHVTDIARLQALGDEGVRAMICDSTNAIRDGVSPSEADVAATLRDVVAKAKYRVAFTTFSSNVARV
RAIAEAAYANDREVVVVGRAMERVIGVAREQGMLDGLPAFRGADAFGFLPRDKVVAILTGSQGEPRAALSRIATDDHPEI
ALSHGDLVVFSSRTIPGNEKVVNTVINGLVKRGIKVMTDKDGLVHVSGHPRRGELEQMYKWVRPQVSVPVHGEPLHLTEH
AALAKALGVPEVVSCADGHVIRLAPGHAERVEDVPYGRLYKDGRLLIPDSARTIPERRRLAYVGIVSVALAVDNRGNLVG
DPSVEITGIPERGEGGIDFLDLILDTVVTTAEGLPKARRRDPDAMSDSIERAVRGAVNGAWGKKPVCHVHIVEV

Specific function: Unknown

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 59585; Mature: 59454

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADNNELVFAPLGGVGEIGMNLGLYGIGPRKQRQWLIVDLGMSFAGEEAPGVDLVMPDIR
CCCCCCEEEEECCCCHHHCCCCCEEECCCCCCCCEEEEEECCCCCCCCCCCCEEECCCHH
FLESVKDRIAGLVLTHGHEDHVGAMLDLWPRIGCPVYTTRFTAALLDAKRLQEPGAPKIP
HHHHHHHHHCEEEEECCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCCCCCCCCC
IEVVRSGGRAQIGPFEVEFVPVAHSIPDSHALAIRTAAGLVLHTGDWKLDPTPVVGHVTD
HHHHCCCCCCCCCCEEEEEEEEECCCCCCCEEEEEEECCEEEECCCCCCCCCCCCHHHHH
IARLQALGDEGVRAMICDSTNAIRDGVSPSEADVAATLRDVVAKAKYRVAFTTFSSNVAR
HHHHHHCCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHCEEEEEEEECCCCHHH
VRAIAEAAYANDREVVVVGRAMERVIGVAREQGMLDGLPAFRGADAFGFLPRDKVVAILT
HHHHHHHHHCCCCEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEE
GSQGEPRAALSRIATDDHPEIALSHGDLVVFSSRTIPGNEKVVNTVINGLVKRGIKVMTD
CCCCCHHHHHHHHCCCCCCCEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEC
KDGLVHVSGHPRRGELEQMYKWVRPQVSVPVHGEPLHLTEHAALAKALGVPEVVSCADGH
CCCEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHCCCCHHHHCCCCC
VIRLAPGHAERVEDVPYGRLYKDGRLLIPDSARTIPERRRLAYVGIVSVALAVDNRGNLV
EEEECCCCHHHHCCCCCCCEECCCEEECCCCCCCCHHHHHEEEEEEEEEEEEECCCCCCC
GDPSVEITGIPERGEGGIDFLDLILDTVVTTAEGLPKARRRDPDAMSDSIERAVRGAVNG
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHCCC
AWGKKPVCHVHIVEV
CCCCCCEEEEEEEEC
>Mature Secondary Structure 
ADNNELVFAPLGGVGEIGMNLGLYGIGPRKQRQWLIVDLGMSFAGEEAPGVDLVMPDIR
CCCCCEEEEECCCCHHHCCCCCEEECCCCCCCCEEEEEECCCCCCCCCCCCEEECCCHH
FLESVKDRIAGLVLTHGHEDHVGAMLDLWPRIGCPVYTTRFTAALLDAKRLQEPGAPKIP
HHHHHHHHHCEEEEECCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCCCCCCCCC
IEVVRSGGRAQIGPFEVEFVPVAHSIPDSHALAIRTAAGLVLHTGDWKLDPTPVVGHVTD
HHHHCCCCCCCCCCEEEEEEEEECCCCCCCEEEEEEECCEEEECCCCCCCCCCCCHHHHH
IARLQALGDEGVRAMICDSTNAIRDGVSPSEADVAATLRDVVAKAKYRVAFTTFSSNVAR
HHHHHHCCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHCEEEEEEEECCCCHHH
VRAIAEAAYANDREVVVVGRAMERVIGVAREQGMLDGLPAFRGADAFGFLPRDKVVAILT
HHHHHHHHHCCCCEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEE
GSQGEPRAALSRIATDDHPEIALSHGDLVVFSSRTIPGNEKVVNTVINGLVKRGIKVMTD
CCCCCHHHHHHHHCCCCCCCEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEC
KDGLVHVSGHPRRGELEQMYKWVRPQVSVPVHGEPLHLTEHAALAKALGVPEVVSCADGH
CCCEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHCCCCHHHHCCCCC
VIRLAPGHAERVEDVPYGRLYKDGRLLIPDSARTIPERRRLAYVGIVSVALAVDNRGNLV
EEEECCCCHHHHCCCCCCCEECCCEEECCCCCCCCHHHHHEEEEEEEEEEEEECCCCCCC
GDPSVEITGIPERGEGGIDFLDLILDTVVTTAEGLPKARRRDPDAMSDSIERAVRGAVNG
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHCCC
AWGKKPVCHVHIVEV
CCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]