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The map label for this gene is atoS [H]

Identifier: 158423276

GI number: 158423276

Start: 1889996

End: 1891768

Strand: Direct

Name: atoS [H]

Synonym: AZC_1652

Alternate gene names: 158423276

Gene position: 1889996-1891768 (Clockwise)

Preceding gene: 158423275

Following gene: 158423277

Centisome position: 35.2

GC content: 67.57

Gene sequence:

>1773_bases
GTGGCCGGCATGTTCTCCCCCACCCGCTGGTGGTCGCGGCTCGCCCTGCGGCCCAAGCTGACGTTGTCTTTCCTGATGGT
CAGCGTGCCGCCGGTTCTGGTGGCGAGCTTCATCGCCGCCCAGACCATGTCGGCGGTTTTCGAGACCAACGTGCAGCAGT
GGATCGGGGAGATCGCGCGCTTCATGGCCAATGAGGCCCAGGAGGCGCAGGAGGAGGCGATGCACGCGACCTCCATCGTG
GCGAAGGCGCTGTCCCAGGCCTCCGCGCAACCGGCCGGCAGCGACACCTCGCTGGAGGCCTTCGCCGACCTGCTCACCTC
GGTGGGATACGATTTCGTGCGCCTCTACGATGGCTCCGGCCGGGTGCTCTATGCCATGGGCGACCTTCAGCTCGCCCGGC
CGCTGCCGCAGGAGCCAGTGGCCTCCATCTTCTTCGCCCACAGCCAGGGCAAGCCGGTGATGCTCGTCGGCGCCGTCCAG
AAGCTTCGGCTGGGCGACGCGGATCATTTCCTCTTCATCGGAAATCTGCTGGACGAGCAGTTCTTCAACGCGCCACAGAC
GATCCGCTCCCTGGACTTGCATCTGGTGGAAGTGCGCCATGAGGGGCGTAAGCTCCAGGACATTACCAGCGGGCAAGGCC
GGCCCGCCGACGTTCCTCCCGATGTGCTCTCCCGCTTGCAGGAAGGTGCGGACAGCGTCAGCCGCGGGGGCGTGATGGGC
GTTGGCCCCGCGGTGGCGTATGCCGCCTTGCGTGACGGCAACCATCATCTCGTCGGCATCGTCATCTGCCGCCTCAATGG
TGCGACGGCACTGTTCGAGCGCCTCGGCACGTGGTGGCTGTTCCTGGCGCTGGCGGCTGTCGCGGGCCTCCTGTCGCTTC
TTGCGGGCATCGGCATGTCGCGCCGGCTCAGCGCGCCCCTGCGTCAGATCACGCAGGGCCTCACCTCTGTGGCCGACGGC
GACTATCGCATCCGGCTGCGGGAGGAAGGCGGGCGGGAGATCGCCGACCTTGCGGCCGGCTTCAACACCATGACGGCGCA
GCTCGAGACCCTGCACGCGCTCGAAGCCAAGATGCGCCACAGCGCGCAACTGGCGACGCTGGGGGAGGCGGCGGCGGTGA
TCGCCCACGAGATCCGCAACCCGCTGGGCATCATCAAGACCTCCACCGAACTGGTGCGGCGCAAGACCCAGCTTGCCCCC
TCCGAAGACCGGCTGATGGGCTTCGTGCTGGAGGAGGTGAACCGCATCGAGCGCCTGGTGGCGGACCTGCTCGATTACGT
GCGGCCCGACCATTTCGAGCGTCACCGCATCGACCTGCTCGCCGAAGTGGTGCAGCCCGCCGTGGATTTCGCCGGCGCTG
AACTCTCCCGCCGCGGCATCAGCCACGTGCTGATCGCGCCGGAAGGGCCGCTGCCGGTCAATGGCGATGTGGACCGGCTC
TATCAGGCCCTGCTCAACCTGCTCCTCAACGCGGCCGACGCCGCCCCGGAGGGCGGGCATGTCATTGTCCGGCTGAAGGC
CTGTTCGGATGAAGTGACCCTGGAGGTGGAGGACAACGGCCCTGGCGTTCCGCCCGATGTGGAGGGCCGCATGTTCGAAC
CCTTCGTGACTTCCAAGGCGAACGGCACCGGCCTTGGCCTTGCCAAAGTCCAATCCACACTGCAGGCCCACGAGGGCGCG
GTGTCCTATCGCAAGGCCCCCGGCGGCGGTGCGATCTTCAGCCTGCGTCTGGCGCTGGCAGAGGATCGTACGCTCGTGGC
GGCCTCCCAATGA

Upstream 100 bases:

>100_bases
CATGGGCGTCGAGGCTCTCGGGCAGACCGTCGCCTGGCATCGGGCGCCGGCCGGACAGGAGCGTTGCGCGCCGCCTGCCA
AGGCTGGTCGCTGAGGCGCC

Downstream 100 bases:

>100_bases
GCCGGCCGGGTGCGGCAGGCGGAGAATGAAGATGGCTCCCGCGATCCTGGTGGTCGATGACGAGAAGCGCCTCGGCGAAG
TGCTCGCGGCGGCGCTGACG

Product: ATP-binding region histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 590; Mature: 589

Protein sequence:

>590_residues
MAGMFSPTRWWSRLALRPKLTLSFLMVSVPPVLVASFIAAQTMSAVFETNVQQWIGEIARFMANEAQEAQEEAMHATSIV
AKALSQASAQPAGSDTSLEAFADLLTSVGYDFVRLYDGSGRVLYAMGDLQLARPLPQEPVASIFFAHSQGKPVMLVGAVQ
KLRLGDADHFLFIGNLLDEQFFNAPQTIRSLDLHLVEVRHEGRKLQDITSGQGRPADVPPDVLSRLQEGADSVSRGGVMG
VGPAVAYAALRDGNHHLVGIVICRLNGATALFERLGTWWLFLALAAVAGLLSLLAGIGMSRRLSAPLRQITQGLTSVADG
DYRIRLREEGGREIADLAAGFNTMTAQLETLHALEAKMRHSAQLATLGEAAAVIAHEIRNPLGIIKTSTELVRRKTQLAP
SEDRLMGFVLEEVNRIERLVADLLDYVRPDHFERHRIDLLAEVVQPAVDFAGAELSRRGISHVLIAPEGPLPVNGDVDRL
YQALLNLLLNAADAAPEGGHVIVRLKACSDEVTLEVEDNGPGVPPDVEGRMFEPFVTSKANGTGLGLAKVQSTLQAHEGA
VSYRKAPGGGAIFSLRLALAEDRTLVAASQ

Sequences:

>Translated_590_residues
MAGMFSPTRWWSRLALRPKLTLSFLMVSVPPVLVASFIAAQTMSAVFETNVQQWIGEIARFMANEAQEAQEEAMHATSIV
AKALSQASAQPAGSDTSLEAFADLLTSVGYDFVRLYDGSGRVLYAMGDLQLARPLPQEPVASIFFAHSQGKPVMLVGAVQ
KLRLGDADHFLFIGNLLDEQFFNAPQTIRSLDLHLVEVRHEGRKLQDITSGQGRPADVPPDVLSRLQEGADSVSRGGVMG
VGPAVAYAALRDGNHHLVGIVICRLNGATALFERLGTWWLFLALAAVAGLLSLLAGIGMSRRLSAPLRQITQGLTSVADG
DYRIRLREEGGREIADLAAGFNTMTAQLETLHALEAKMRHSAQLATLGEAAAVIAHEIRNPLGIIKTSTELVRRKTQLAP
SEDRLMGFVLEEVNRIERLVADLLDYVRPDHFERHRIDLLAEVVQPAVDFAGAELSRRGISHVLIAPEGPLPVNGDVDRL
YQALLNLLLNAADAAPEGGHVIVRLKACSDEVTLEVEDNGPGVPPDVEGRMFEPFVTSKANGTGLGLAKVQSTLQAHEGA
VSYRKAPGGGAIFSLRLALAEDRTLVAASQ
>Mature_589_residues
AGMFSPTRWWSRLALRPKLTLSFLMVSVPPVLVASFIAAQTMSAVFETNVQQWIGEIARFMANEAQEAQEEAMHATSIVA
KALSQASAQPAGSDTSLEAFADLLTSVGYDFVRLYDGSGRVLYAMGDLQLARPLPQEPVASIFFAHSQGKPVMLVGAVQK
LRLGDADHFLFIGNLLDEQFFNAPQTIRSLDLHLVEVRHEGRKLQDITSGQGRPADVPPDVLSRLQEGADSVSRGGVMGV
GPAVAYAALRDGNHHLVGIVICRLNGATALFERLGTWWLFLALAAVAGLLSLLAGIGMSRRLSAPLRQITQGLTSVADGD
YRIRLREEGGREIADLAAGFNTMTAQLETLHALEAKMRHSAQLATLGEAAAVIAHEIRNPLGIIKTSTELVRRKTQLAPS
EDRLMGFVLEEVNRIERLVADLLDYVRPDHFERHRIDLLAEVVQPAVDFAGAELSRRGISHVLIAPEGPLPVNGDVDRLY
QALLNLLLNAADAAPEGGHVIVRLKACSDEVTLEVEDNGPGVPPDVEGRMFEPFVTSKANGTGLGLAKVQSTLQAHEGAV
SYRKAPGGGAIFSLRLALAEDRTLVAASQ

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=259, Percent_Identity=34.7490347490347, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1790436, Length=230, Percent_Identity=32.1739130434783, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1790346, Length=287, Percent_Identity=27.8745644599303, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1786600, Length=214, Percent_Identity=28.5046728971963, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1786783, Length=288, Percent_Identity=26.7361111111111, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788393, Length=296, Percent_Identity=27.027027027027, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1790300, Length=226, Percent_Identity=30.5309734513274, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1790861, Length=374, Percent_Identity=29.6791443850267, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI87081816, Length=338, Percent_Identity=27.5147928994083, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI145693157, Length=225, Percent_Identity=28.4444444444444, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1789149, Length=333, Percent_Identity=23.7237237237237, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790551, Length=193, Percent_Identity=29.0155440414508, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789808, Length=274, Percent_Identity=27.007299270073, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1786912, Length=287, Percent_Identity=29.616724738676, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI48994928, Length=227, Percent_Identity=29.0748898678414, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63587; Mature: 63456

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGMFSPTRWWSRLALRPKLTLSFLMVSVPPVLVASFIAAQTMSAVFETNVQQWIGEIAR
CCCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMANEAQEAQEEAMHATSIVAKALSQASAQPAGSDTSLEAFADLLTSVGYDFVRLYDGSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCC
RVLYAMGDLQLARPLPQEPVASIFFAHSQGKPVMLVGAVQKLRLGDADHFLFIGNLLDEQ
EEEEEECCCHHCCCCCCCHHHHHHEECCCCCCEEEEECHHHHHCCCCCCEEEHHHHHHHH
FFNAPQTIRSLDLHLVEVRHEGRKLQDITSGQGRPADVPPDVLSRLQEGADSVSRGGVMG
HCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
VGPAVAYAALRDGNHHLVGIVICRLNGATALFERLGTWWLFLALAAVAGLLSLLAGIGMS
CCHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
RRLSAPLRQITQGLTSVADGDYRIRLREEGGREIADLAAGFNTMTAQLETLHALEAKMRH
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHH
SAQLATLGEAAAVIAHEIRNPLGIIKTSTELVRRKTQLAPSEDRLMGFVLEEVNRIERLV
HHHHHHHHHHHHHHHHHHCCCHHEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ADLLDYVRPDHFERHRIDLLAEVVQPAVDFAGAELSRRGISHVLIAPEGPLPVNGDVDRL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEECCCCCCCCCCCHHHH
YQALLNLLLNAADAAPEGGHVIVRLKACSDEVTLEVEDNGPGVPPDVEGRMFEPFVTSKA
HHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCCCCCEECCHHCCCC
NGTGLGLAKVQSTLQAHEGAVSYRKAPGGGAIFSLRLALAEDRTLVAASQ
CCCCCHHHHHHHHHHHHCCCHHCCCCCCCCCEEEEEEEHHCCCEEEEECC
>Mature Secondary Structure 
AGMFSPTRWWSRLALRPKLTLSFLMVSVPPVLVASFIAAQTMSAVFETNVQQWIGEIAR
CCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMANEAQEAQEEAMHATSIVAKALSQASAQPAGSDTSLEAFADLLTSVGYDFVRLYDGSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCC
RVLYAMGDLQLARPLPQEPVASIFFAHSQGKPVMLVGAVQKLRLGDADHFLFIGNLLDEQ
EEEEEECCCHHCCCCCCCHHHHHHEECCCCCCEEEEECHHHHHCCCCCCEEEHHHHHHHH
FFNAPQTIRSLDLHLVEVRHEGRKLQDITSGQGRPADVPPDVLSRLQEGADSVSRGGVMG
HCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
VGPAVAYAALRDGNHHLVGIVICRLNGATALFERLGTWWLFLALAAVAGLLSLLAGIGMS
CCHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
RRLSAPLRQITQGLTSVADGDYRIRLREEGGREIADLAAGFNTMTAQLETLHALEAKMRH
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHH
SAQLATLGEAAAVIAHEIRNPLGIIKTSTELVRRKTQLAPSEDRLMGFVLEEVNRIERLV
HHHHHHHHHHHHHHHHHHCCCHHEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ADLLDYVRPDHFERHRIDLLAEVVQPAVDFAGAELSRRGISHVLIAPEGPLPVNGDVDRL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEECCCCCCCCCCCHHHH
YQALLNLLLNAADAAPEGGHVIVRLKACSDEVTLEVEDNGPGVPPDVEGRMFEPFVTSKA
HHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCCCCCEECCHHCCCC
NGTGLGLAKVQSTLQAHEGAVSYRKAPGGGAIFSLRLALAEDRTLVAASQ
CCCCCHHHHHHHHHHHHCCCHHCCCCCCCCCEEEEEEEHHCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]