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The map label for this gene is clpA [C]

Identifier: 158423219

GI number: 158423219

Start: 1819602

End: 1822055

Strand: Direct

Name: clpA [C]

Synonym: AZC_1595

Alternate gene names: 158423219

Gene position: 1819602-1822055 (Clockwise)

Preceding gene: 158423218

Following gene: 158423223

Centisome position: 33.89

GC content: 66.3

Gene sequence:

>2454_bases
ATGCCTACATTTTCCCGCAGCCTCGAACAGTCGCTCCATCGCGCTCTGGCTCTCGCGAACGAACGCCACCACGAATATGC
GACTCTCGAGCACCTGCTGCTCTCGCTGGTGGATGATCAGGACGCGGCTGCGGTCATGCGGGCCTGCAACGTCGATCTCG
ACAAGCTCCGCCGCAACCTCGTCGAGTATGTGGACACGGAACTCGAAAACCTGGTGCAGGCCGGAGGCGACGATTCCAAG
CCGACCGCCGGCTTCCAGCGCGTGATCCAGCGCGCGGTGATCCACGTCCAGTCCTCCGGCCGCGAGGAAGTGACCGGCGC
CAACGTGCTGGTCGCCATCTTCGCCGAGCGCGAGAGCCATGCCGCCTATTTCCTGCAGGAGCAGGACATGACGCGGTACG
ACGCGGTGAACTACATCTCCCACGGCATCGCCAAGCGGGCCGGCATGTCCGAGAGCCGCCCCGTGCGGGGCGCCGAGGAC
GAGACCGAGACCAAGTCCGGCGAGGAGCCGAAGAAGAAGGCGGATGCGCTCGACGCCTATTGCGTGAACCTCAACAAGAA
GGCGCACGAGGGCAAGATCGATCCACTCATCGGCCGCGACAAGGAAATCCAGCGCACCATCCAGGTGCTCTGCCGCCGGC
AGAAGAACAACCCGTTGTTCGTGGGTGATCCGGGCGTCGGCAAGACCGCCATCGCCGAAGGCCTTGCGCGCCGCATCATC
AATGGCGACGTGCCGGAGGTGCTCGCCACCGCCACCATCTTCGCCCTCGACATGGGCGCGCTGCTCGCCGGCACCCGCTA
TCGCGGCGACTTCGAGGAGCGTCTCAAGCAGGTGGTGAAGGAGATCGAGGCCTACCCGAACGCCATCATGTTCATCGACG
AGATCCACACGGTGATCGGCGCCGGTGCGACCTCGGGCGGCGCCATGGATGCCTCGAACCTGCTGAAGCCGGCGCTGGCC
TCGGGCACGCTGCGCTGCATGGGCTCGACCACCTACAAGGAATACCGCCAGTATTTCGAGAAGGACCGGGCGCTGGTGCG
CCGCTTCCAGAAGATCGACGTGGCCGAGCCGACCGTGCCGGACACCATCGAGATCCTGAAGGGCCTCAAGCCTTACTTCG
AGGACTATCACAAGCTGCGCTACACCAACGAGGCCATCAAGGCCGCGGTGGAACTCTCGGCCCGCTATATCCATGACCGC
AAGCTCCCCGACAAGGCGATCGACGTGATCGACGAGAGCGGCGCGGCGCAGATGCTGGTGCCCGAGGCGCGGCGCAAGAA
GACCATCGGCCTCAAGGAGATCGAGGCGACCGTCGCAACCATGGCGCGCATCCCGCCCAAGTCCGTCTCCAAGGACGACA
CGGAGATGCTGTCCAACCTCGAAACCACGCTGAAGCGCGTGGTGTACGGGCAGGACAAGGCCATCGAGGCGCTCGCCTCC
TCCATCAAGCTCGCCCGGGCGGGCCTGCGGGAACCGGAGAAGCCCATCGGCTCCTACCTGTTCTCCGGCCCCACCGGCGT
CGGCAAGACGGAAGTGGCCAAGCAGCTGGCCTCGACCCTCGGCGTGAACCTCCTGCGCTTCGACATGTCGGAGTATATGG
AGCGCCATACCGTGAGCCGCCTCATCGGCGCGCCTCCCGGCTATGTGGGCTTCGATCAGGGCGGCCTGCTCACCGATGGC
GTGGACCAGACCCCGCATTGCGTGCTGCTGCTGGACGAGATCGAGAAGGCCCATCCGGACCTCTTCAACATCCTCCTGCA
GGTGATGGACCACGGGAAGCTCACCGACCATAACGGCAAGCAGGTGGACTTCCGCAACGTGATCCTAATCATGACCACGA
ATGCGGGTGCGGCGGACCTCTCCCGTGCAGCCTACGGCTTCACCCGCAACAAGCGGGAGGGCGACGACGTGGAGGCGATC
AACCGCACCTTCGCGCCGGAATTCCGCAACCGTCTCGATGCGGTGATCCCCTTCGCCCACCTCTCGCCCGAGATCATTGG
TCTGGTGGTGGAGAAGTTCGTCCTTCAGCTGGAGGCCCAGCTCGCCGACCGGAACGTCACCATCGGCCTGTCCGACGAGG
CGACCCGCTGGCTGGTGGATCGCGGCTATGACGAGCAGATGGGCGCCCGTCCCATGGGCCGCGTCATCCAGGAGTTCATC
AAGACGCCGCTGGCGGACGAGGTGCTCTTCGGCCGGCTCAAGAATGGTGGCCACGTCCGCGTGGTCGTGGTGGGCGAGGG
CACGGCGGCGAAGCTCGGCTTCGAGTTCCCCGACGGCCCGATCACCCCGAAGCCGGACAAGATCCAGCCGGCCGCTCCCA
AGCGGGCGCCCCGCAAGCGCGCCGCGCCCCGCACCTCCAAGGACGGCGGCAAGGGCGGGCCGAAGGGCGGTGGCTCCGGC
GGCAGCCCGCGCCGGGGCAGCCCGGTGCCGAAGGTGCCGCTGGTCAAGGCCTGA

Upstream 100 bases:

>100_bases
TGCGCAGCGGGGAGGTCGGTACGAAGTTTTACGGAGCGCGTGCATGTTCGAGTTGGCGGACTGTCCGTCTTCTCGATCAG
GGCACGAGATAGAGGTGTCG

Downstream 100 bases:

>100_bases
ACGGTCCGGCACAGACAGTCAAAGGGCGGCTTCGGCCGCCCTTTTTCATGGGTGCTGGCTTGAAGCGGGTTGCGCCTCGA
AAGCGGCGCGCGTCAGCCGA

Product: ATPase AAA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 817; Mature: 816

Protein sequence:

>817_residues
MPTFSRSLEQSLHRALALANERHHEYATLEHLLLSLVDDQDAAAVMRACNVDLDKLRRNLVEYVDTELENLVQAGGDDSK
PTAGFQRVIQRAVIHVQSSGREEVTGANVLVAIFAERESHAAYFLQEQDMTRYDAVNYISHGIAKRAGMSESRPVRGAED
ETETKSGEEPKKKADALDAYCVNLNKKAHEGKIDPLIGRDKEIQRTIQVLCRRQKNNPLFVGDPGVGKTAIAEGLARRII
NGDVPEVLATATIFALDMGALLAGTRYRGDFEERLKQVVKEIEAYPNAIMFIDEIHTVIGAGATSGGAMDASNLLKPALA
SGTLRCMGSTTYKEYRQYFEKDRALVRRFQKIDVAEPTVPDTIEILKGLKPYFEDYHKLRYTNEAIKAAVELSARYIHDR
KLPDKAIDVIDESGAAQMLVPEARRKKTIGLKEIEATVATMARIPPKSVSKDDTEMLSNLETTLKRVVYGQDKAIEALAS
SIKLARAGLREPEKPIGSYLFSGPTGVGKTEVAKQLASTLGVNLLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDG
VDQTPHCVLLLDEIEKAHPDLFNILLQVMDHGKLTDHNGKQVDFRNVILIMTTNAGAADLSRAAYGFTRNKREGDDVEAI
NRTFAPEFRNRLDAVIPFAHLSPEIIGLVVEKFVLQLEAQLADRNVTIGLSDEATRWLVDRGYDEQMGARPMGRVIQEFI
KTPLADEVLFGRLKNGGHVRVVVVGEGTAAKLGFEFPDGPITPKPDKIQPAAPKRAPRKRAAPRTSKDGGKGGPKGGGSG
GSPRRGSPVPKVPLVKA

Sequences:

>Translated_817_residues
MPTFSRSLEQSLHRALALANERHHEYATLEHLLLSLVDDQDAAAVMRACNVDLDKLRRNLVEYVDTELENLVQAGGDDSK
PTAGFQRVIQRAVIHVQSSGREEVTGANVLVAIFAERESHAAYFLQEQDMTRYDAVNYISHGIAKRAGMSESRPVRGAED
ETETKSGEEPKKKADALDAYCVNLNKKAHEGKIDPLIGRDKEIQRTIQVLCRRQKNNPLFVGDPGVGKTAIAEGLARRII
NGDVPEVLATATIFALDMGALLAGTRYRGDFEERLKQVVKEIEAYPNAIMFIDEIHTVIGAGATSGGAMDASNLLKPALA
SGTLRCMGSTTYKEYRQYFEKDRALVRRFQKIDVAEPTVPDTIEILKGLKPYFEDYHKLRYTNEAIKAAVELSARYIHDR
KLPDKAIDVIDESGAAQMLVPEARRKKTIGLKEIEATVATMARIPPKSVSKDDTEMLSNLETTLKRVVYGQDKAIEALAS
SIKLARAGLREPEKPIGSYLFSGPTGVGKTEVAKQLASTLGVNLLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDG
VDQTPHCVLLLDEIEKAHPDLFNILLQVMDHGKLTDHNGKQVDFRNVILIMTTNAGAADLSRAAYGFTRNKREGDDVEAI
NRTFAPEFRNRLDAVIPFAHLSPEIIGLVVEKFVLQLEAQLADRNVTIGLSDEATRWLVDRGYDEQMGARPMGRVIQEFI
KTPLADEVLFGRLKNGGHVRVVVVGEGTAAKLGFEFPDGPITPKPDKIQPAAPKRAPRKRAAPRTSKDGGKGGPKGGGSG
GSPRRGSPVPKVPLVKA
>Mature_816_residues
PTFSRSLEQSLHRALALANERHHEYATLEHLLLSLVDDQDAAAVMRACNVDLDKLRRNLVEYVDTELENLVQAGGDDSKP
TAGFQRVIQRAVIHVQSSGREEVTGANVLVAIFAERESHAAYFLQEQDMTRYDAVNYISHGIAKRAGMSESRPVRGAEDE
TETKSGEEPKKKADALDAYCVNLNKKAHEGKIDPLIGRDKEIQRTIQVLCRRQKNNPLFVGDPGVGKTAIAEGLARRIIN
GDVPEVLATATIFALDMGALLAGTRYRGDFEERLKQVVKEIEAYPNAIMFIDEIHTVIGAGATSGGAMDASNLLKPALAS
GTLRCMGSTTYKEYRQYFEKDRALVRRFQKIDVAEPTVPDTIEILKGLKPYFEDYHKLRYTNEAIKAAVELSARYIHDRK
LPDKAIDVIDESGAAQMLVPEARRKKTIGLKEIEATVATMARIPPKSVSKDDTEMLSNLETTLKRVVYGQDKAIEALASS
IKLARAGLREPEKPIGSYLFSGPTGVGKTEVAKQLASTLGVNLLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDGV
DQTPHCVLLLDEIEKAHPDLFNILLQVMDHGKLTDHNGKQVDFRNVILIMTTNAGAADLSRAAYGFTRNKREGDDVEAIN
RTFAPEFRNRLDAVIPFAHLSPEIIGLVVEKFVLQLEAQLADRNVTIGLSDEATRWLVDRGYDEQMGARPMGRVIQEFIK
TPLADEVLFGRLKNGGHVRVVVVGEGTAAKLGFEFPDGPITPKPDKIQPAAPKRAPRKRAAPRTSKDGGKGGPKGGGSGG
SPRRGSPVPKVPLVKA

Specific function: ATP-Dependent Specificity Component Of The Clpp Protease. It Directs The Protease To Specific Substrates. The Primary Function Of The Clpa-Clpp Complex Appears To Be The Degradation Of Unfolded Or Abnormal Proteins. [C]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=356, Percent_Identity=33.1460674157303, Blast_Score=172, Evalue=1e-42,
Organism=Escherichia coli, GI1787109, Length=753, Percent_Identity=57.6361221779549, Blast_Score=896, Evalue=0.0,
Organism=Escherichia coli, GI1788943, Length=418, Percent_Identity=43.5406698564593, Blast_Score=308, Evalue=7e-85,
Organism=Saccharomyces cerevisiae, GI6320464, Length=325, Percent_Identity=45.2307692307692, Blast_Score=284, Evalue=4e-77,
Organism=Saccharomyces cerevisiae, GI6323002, Length=295, Percent_Identity=45.4237288135593, Blast_Score=254, Evalue=3e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR013461
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 89674; Mature: 89542

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTFSRSLEQSLHRALALANERHHEYATLEHLLLSLVDDQDAAAVMRACNVDLDKLRRNL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHH
VEYVDTELENLVQAGGDDSKPTAGFQRVIQRAVIHVQSSGREEVTGANVLVAIFAERESH
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCC
AAYFLQEQDMTRYDAVNYISHGIAKRAGMSESRPVRGAEDETETKSGEEPKKKADALDAY
CEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHH
CVNLNKKAHEGKIDPLIGRDKEIQRTIQVLCRRQKNNPLFVGDPGVGKTAIAEGLARRII
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHH
NGDVPEVLATATIFALDMGALLAGTRYRGDFEERLKQVVKEIEAYPNAIMFIDEIHTVIG
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHH
AGATSGGAMDASNLLKPALASGTLRCMGSTTYKEYRQYFEKDRALVRRFQKIDVAEPTVP
CCCCCCCCCCHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DTIEILKGLKPYFEDYHKLRYTNEAIKAAVELSARYIHDRKLPDKAIDVIDESGAAQMLV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEC
PEARRKKTIGLKEIEATVATMARIPPKSVSKDDTEMLSNLETTLKRVVYGQDKAIEALAS
CHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
SIKLARAGLREPEKPIGSYLFSGPTGVGKTEVAKQLASTLGVNLLRFDMSEYMERHTVSR
HHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
LIGAPPGYVGFDQGGLLTDGVDQTPHCVLLLDEIEKAHPDLFNILLQVMDHGKLTDHNGK
HHCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHCHHHHHHHHHHHHCCCCCCCCCC
QVDFRNVILIMTTNAGAADLSRAAYGFTRNKREGDDVEAINRTFAPEFRNRLDAVIPFAH
EEEECCEEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCHHH
LSPEIIGLVVEKFVLQLEAQLADRNVTIGLSDEATRWLVDRGYDEQMGARPMGRVIQEFI
CCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHCCCCHHHCCCHHHHHHHHHH
KTPLADEVLFGRLKNGGHVRVVVVGEGTAAKLGFEFPDGPITPKPDKIQPAAPKRAPRKR
HCCCHHHHHHHHCCCCCEEEEEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHH
AAPRTSKDGGKGGPKGGGSGGSPRRGSPVPKVPLVKA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PTFSRSLEQSLHRALALANERHHEYATLEHLLLSLVDDQDAAAVMRACNVDLDKLRRNL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHH
VEYVDTELENLVQAGGDDSKPTAGFQRVIQRAVIHVQSSGREEVTGANVLVAIFAERESH
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCC
AAYFLQEQDMTRYDAVNYISHGIAKRAGMSESRPVRGAEDETETKSGEEPKKKADALDAY
CEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHH
CVNLNKKAHEGKIDPLIGRDKEIQRTIQVLCRRQKNNPLFVGDPGVGKTAIAEGLARRII
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHH
NGDVPEVLATATIFALDMGALLAGTRYRGDFEERLKQVVKEIEAYPNAIMFIDEIHTVIG
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHH
AGATSGGAMDASNLLKPALASGTLRCMGSTTYKEYRQYFEKDRALVRRFQKIDVAEPTVP
CCCCCCCCCCHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DTIEILKGLKPYFEDYHKLRYTNEAIKAAVELSARYIHDRKLPDKAIDVIDESGAAQMLV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEC
PEARRKKTIGLKEIEATVATMARIPPKSVSKDDTEMLSNLETTLKRVVYGQDKAIEALAS
CHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
SIKLARAGLREPEKPIGSYLFSGPTGVGKTEVAKQLASTLGVNLLRFDMSEYMERHTVSR
HHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
LIGAPPGYVGFDQGGLLTDGVDQTPHCVLLLDEIEKAHPDLFNILLQVMDHGKLTDHNGK
HHCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHCHHHHHHHHHHHHCCCCCCCCCC
QVDFRNVILIMTTNAGAADLSRAAYGFTRNKREGDDVEAINRTFAPEFRNRLDAVIPFAH
EEEECCEEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCHHH
LSPEIIGLVVEKFVLQLEAQLADRNVTIGLSDEATRWLVDRGYDEQMGARPMGRVIQEFI
CCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHCCCCHHHCCCHHHHHHHHHH
KTPLADEVLFGRLKNGGHVRVVVVGEGTAAKLGFEFPDGPITPKPDKIQPAAPKRAPRKR
HCCCHHHHHHHHCCCCCEEEEEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHH
AAPRTSKDGGKGGPKGGGSGGSPRRGSPVPKVPLVKA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6209404 [H]