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The map label for this gene is matE [H]

Identifier: 158423004

GI number: 158423004

Start: 1562158

End: 1563528

Strand: Direct

Name: matE [H]

Synonym: AZC_1380

Alternate gene names: 158423004

Gene position: 1562158-1563528 (Clockwise)

Preceding gene: 158423003

Following gene: 158423007

Centisome position: 29.09

GC content: 70.46

Gene sequence:

>1371_bases
ATGGATGCGCGCACCCGCCTTTTGCTGGAGGCTCCTCCCGGCCGCACCATCCTGCGTCTGGCCTGGCCCAATGTCCTCGT
CATGGCCGCGCAGGCGGCTGTGGGATTGATCGAGACCTATTTCGTCGCCAAGCTCGGTGCCGATGCCCTCGCCGGCATGT
CGTTGGTCTTCCCCGTCCTGATGCTGCTCCAGATGGTCTCGGCCGGCGCGGTGGGCGGGGCGGTACTCTCGGCGGTGGCC
CGCGCCCTCGGTGCCGATGACCGGCGGCGTGTGAACCAGGTGGTCTGGACGAGCGTCCTGCTCACCCTCGGGCTCAGCGG
CGCCACCACGGTCGGCGTGATCCTGGGTGGCCCCTGGCTCTACGCGGTCATGGGGGGAACGGGCGGCGGCCTTGCGGCCG
CGCTCACCTATTCCGGCATCGTTTTTGTTGGTGCGGTGCCACTCTGGCTCTTCAACACCTTCGCGGCGATGATCCGGGGC
ACCGGCAACATGCTGGTGCCCGCGCTGGTGATCGTCGGTGGGGCACTGGTCCTCATCCCGCTGTCGCCGATGCTCATCTT
CGGGGTCGGCCCCTTTCCCCAGCTCGGCGTTGCGGGCGGCGCCGTGGCGGTGCTCGGCTATTATGTGGCGGGCGCCGTGA
TCCTCGGCTGGTACATCTGGTCTGGGCAAGGCGTGCTGAAGCCCTCGGCACTGCCGCCCAGCCTGTCCGTGGGGCCGGCG
CTCGACATCCTGCGCATCGGTGCGGCCTCCACCGTCAATGCCTTCTCGACCAATGTCACGGTGGCAGCGACGCTCTCGCT
GGTCAGCGCGGTGAACCCGGCCCTCGTGGCGGGCTATGGCGCCGGCGTGCGGCTGGAATATCTGCTGGTGCCGCTCGTCT
TCGGTATCGGCGCCCCGGCCGCGGCCATGGCGGGCGCGAGCATGGGCGCGGGCAATCTCCGGCGTGCCGGGCAGGTGGCC
TGGGTCGCTGCCGGCATGGCGGCTCTCATCACCGAGGCCATCGGCCTTGGCGCGGCCCTTGCGCCTGAGCCCTGGATCCG
CCTGTTCTCCACCGAGCCGGATATCGTGGCGGGCGGCGCGGCCTATCTTCGGGCCGTGGGGCCAGCTTACGGCTTCTTCG
GTGCCGGCTTCGCGCTCTATTTCGCCTCGCAGGGGGCGGGCCGCATCGGCATTCCGCTTATCGCCGCCATCCTGCGCGTC
GCCGTCACGGTGGGGCTCGGCCGCCTGGCCATGCAGGCTTTCGGAACCGGCGGTCTCTATCTCGCCCTTGCCTCGGGTCT
TGCCCTCTATGCGGCCACCAACGCACTCGCGGTCCGCCTATGGTCGCGGCGGGCGCCGAGGGCGGCACGGTCGCCGGTGC
CGGAGGCCTAG

Upstream 100 bases:

>100_bases
TCAGGCGATGCTGCCGCACCTCTCCAGTTCCGCCGTGGCGCCCCGTTACCGGGCGGGTGCCGACGCCGGCGCGCTCTGAG
GGAAACGGGAGGAGCCTGTC

Downstream 100 bases:

>100_bases
AAATCCTGATCCTGGCCGTCCGCTTGTGGCGCGGCAGGCTCTGGATGGCATCGCCCCTCATCGGCACATGGCTTGTGTTC
GCAACCATGGCGCATCAGGC

Product: multi anti extrusion protein

Products: NA

Alternate protein names: Multidrug-efflux transporter [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MDARTRLLLEAPPGRTILRLAWPNVLVMAAQAAVGLIETYFVAKLGADALAGMSLVFPVLMLLQMVSAGAVGGAVLSAVA
RALGADDRRRVNQVVWTSVLLTLGLSGATTVGVILGGPWLYAVMGGTGGGLAAALTYSGIVFVGAVPLWLFNTFAAMIRG
TGNMLVPALVIVGGALVLIPLSPMLIFGVGPFPQLGVAGGAVAVLGYYVAGAVILGWYIWSGQGVLKPSALPPSLSVGPA
LDILRIGAASTVNAFSTNVTVAATLSLVSAVNPALVAGYGAGVRLEYLLVPLVFGIGAPAAAMAGASMGAGNLRRAGQVA
WVAAGMAALITEAIGLGAALAPEPWIRLFSTEPDIVAGGAAYLRAVGPAYGFFGAGFALYFASQGAGRIGIPLIAAILRV
AVTVGLGRLAMQAFGTGGLYLALASGLALYAATNALAVRLWSRRAPRAARSPVPEA

Sequences:

>Translated_456_residues
MDARTRLLLEAPPGRTILRLAWPNVLVMAAQAAVGLIETYFVAKLGADALAGMSLVFPVLMLLQMVSAGAVGGAVLSAVA
RALGADDRRRVNQVVWTSVLLTLGLSGATTVGVILGGPWLYAVMGGTGGGLAAALTYSGIVFVGAVPLWLFNTFAAMIRG
TGNMLVPALVIVGGALVLIPLSPMLIFGVGPFPQLGVAGGAVAVLGYYVAGAVILGWYIWSGQGVLKPSALPPSLSVGPA
LDILRIGAASTVNAFSTNVTVAATLSLVSAVNPALVAGYGAGVRLEYLLVPLVFGIGAPAAAMAGASMGAGNLRRAGQVA
WVAAGMAALITEAIGLGAALAPEPWIRLFSTEPDIVAGGAAYLRAVGPAYGFFGAGFALYFASQGAGRIGIPLIAAILRV
AVTVGLGRLAMQAFGTGGLYLALASGLALYAATNALAVRLWSRRAPRAARSPVPEA
>Mature_456_residues
MDARTRLLLEAPPGRTILRLAWPNVLVMAAQAAVGLIETYFVAKLGADALAGMSLVFPVLMLLQMVSAGAVGGAVLSAVA
RALGADDRRRVNQVVWTSVLLTLGLSGATTVGVILGGPWLYAVMGGTGGGLAAALTYSGIVFVGAVPLWLFNTFAAMIRG
TGNMLVPALVIVGGALVLIPLSPMLIFGVGPFPQLGVAGGAVAVLGYYVAGAVILGWYIWSGQGVLKPSALPPSLSVGPA
LDILRIGAASTVNAFSTNVTVAATLSLVSAVNPALVAGYGAGVRLEYLLVPLVFGIGAPAAAMAGASMGAGNLRRAGQVA
WVAAGMAALITEAIGLGAALAPEPWIRLFSTEPDIVAGGAAYLRAVGPAYGFFGAGFALYFASQGAGRIGIPLIAAILRV
AVTVGLGRLAMQAFGTGGLYLALASGLALYAATNALAVRLWSRRAPRAARSPVPEA

Specific function: Multidrug efflux pump [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 45882; Mature: 45882

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDARTRLLLEAPPGRTILRLAWPNVLVMAAQAAVGLIETYFVAKLGADALAGMSLVFPVL
CCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
MLLQMVSAGAVGGAVLSAVARALGADDRRRVNQVVWTSVLLTLGLSGATTVGVILGGPWL
HHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEE
YAVMGGTGGGLAAALTYSGIVFVGAVPLWLFNTFAAMIRGTGNMLVPALVIVGGALVLIP
EEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHEEEE
LSPMLIFGVGPFPQLGVAGGAVAVLGYYVAGAVILGWYIWSGQGVLKPSALPPSLSVGPA
CCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
LDILRIGAASTVNAFSTNVTVAATLSLVSAVNPALVAGYGAGVRLEYLLVPLVFGIGAPA
HHHHHHCCCHHHHHHCCCCHHHHHHHHHHHCCCHHEECCCCCCCHHHHHHHHHHHCCCCH
AAMAGASMGAGNLRRAGQVAWVAAGMAALITEAIGLGAALAPEPWIRLFSTEPDIVAGGA
HHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEECCCCCEEECHH
AYLRAVGPAYGFFGAGFALYFASQGAGRIGIPLIAAILRVAVTVGLGRLAMQAFGTGGLY
HHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LALASGLALYAATNALAVRLWSRRAPRAARSPVPEA
HHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MDARTRLLLEAPPGRTILRLAWPNVLVMAAQAAVGLIETYFVAKLGADALAGMSLVFPVL
CCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
MLLQMVSAGAVGGAVLSAVARALGADDRRRVNQVVWTSVLLTLGLSGATTVGVILGGPWL
HHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEE
YAVMGGTGGGLAAALTYSGIVFVGAVPLWLFNTFAAMIRGTGNMLVPALVIVGGALVLIP
EEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHEEEE
LSPMLIFGVGPFPQLGVAGGAVAVLGYYVAGAVILGWYIWSGQGVLKPSALPPSLSVGPA
CCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
LDILRIGAASTVNAFSTNVTVAATLSLVSAVNPALVAGYGAGVRLEYLLVPLVFGIGAPA
HHHHHHCCCHHHHHHCCCCHHHHHHHHHHHCCCHHEECCCCCCCHHHHHHHHHHHCCCCH
AAMAGASMGAGNLRRAGQVAWVAAGMAALITEAIGLGAALAPEPWIRLFSTEPDIVAGGA
HHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEECCCCCEEECHH
AYLRAVGPAYGFFGAGFALYFASQGAGRIGIPLIAAILRVAVTVGLGRLAMQAFGTGGLY
HHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LALASGLALYAATNALAVRLWSRRAPRAARSPVPEA
HHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]