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The map label for this gene is 158422998

Identifier: 158422998

GI number: 158422998

Start: 1554418

End: 1555779

Strand: Direct

Name: 158422998

Synonym: AZC_1374

Alternate gene names: NA

Gene position: 1554418-1555779 (Clockwise)

Preceding gene: 158422997

Following gene: 158422999

Centisome position: 28.95

GC content: 61.89

Gene sequence:

>1362_bases
ATGTCCAAGCGCATTGCCATTCTGGGCGGCGGCCCCAGCGGTCTCGCTGTGCTCCGCGCCTTCGAGAGCGCCCGCCGGAA
GGGAGCCGAGATTCCGGAGATCGTCTGCTACGAGAAGCAGAGCGACTGCGGCGGCATGTGGAACTACAACTGGCGCACGG
GCCTCGATGAATTCGGCGAGCCAGTGCATGCCAGCATGTATCGCTATCTGTGGTCCAACGGGCCGAAGGAATGCCTGGAA
TTCGCCGATTATTCATTCGAGGAGCATTTCGGCCGTCCCATTCCCTCCTTCCCGCCGCGCGCGGTGCTGCATGATTACAT
CAAGGGCCGCATCGAGAAGAGCAATGTGCGCGGCTACATCAAGCTCAATCACGCGGTCCGCCACGTAACCTATGACGCGG
GAACGGAGAAATTCCTCGTCACGGTGAAGGATCTGAAAGCCGACGTGCTGGAGACCTCCGCCTTCGATTATGTGGTCTGC
GCCACCGGGCACTTCTCCACCCCCAACGTGCCCTATTTCGAGGGCGTGGAGGCCTTTCCGGGCCGCGTTCTGCATGCCCA
CGATTTCCGCTCGGCGGACGAGTTCGCGGGCAAGAACGTGCTGCTGATCGGGGCCAGCTATTCGTCCGAGGACATCGGCA
TCCAGTGCATGAAGTATGGCGCCAAATCGGTCACCTTCAGCTATCGCACCAAGGCGATGGGCTTCGACTGGCCGGAAGGC
TTTTCCGAGGTGCCGCTGCTGGAGAAGGTTGTCGGCAAGATCGCCCACTTCAAGGACGGGACGCGCAAGGAGGTGGATGC
CATCGTGCTCTGCACGGGCTATCTCCACCACTATCCCTTCCTCGATGACGATCTGCGCCTGAAGTCGCGCAACCGCCTCT
ATCCGGAAGGGCTCTACAAGGGCATCTTCTGGGTGCCCAACCCGCGCTTCATGTATGTCGGCGCGCAGGATCAGTTCTTC
ACCTTCAACATGTTCGACGCGCAGGCCTGGTACGCCCGCGACGTCGTCCTCGGCCGCATTCCGCTGCCCGATGCCGCCGC
CATGGAGGCTGACATCAAGGGCTGGGTGGCCAAGGAAGAAGCGCTCGAAGACGCCTCGCAGATGATCGACTTTCAGACCG
AATATGTGCGCGAACTGATCCTCGCCACCGACTATCCGCGCCTCGACGTCGATGAGGTGGCCCGCATGTTCAAGGAGTGG
GAGCACCACAAGGTCGAGAACATCCTCACCTATCGCGACCGCAGCCACCGCTCGACCCTCACCGGCACGCTGGCGCCCAA
GCACCATACGCCATGGATGCAGGCACTGGACGACAGCCTGGAAGCCTTCCTCGCCACCATGCCCAGCCAGGCCGCGGAAT
GA

Upstream 100 bases:

>100_bases
CGTCCGCGGCCCACCCGCACGAACCATTGCCCCAGCGCCGGACGGCTCCGTCCGGCGAACGGGAACCCATGCCTTCAATC
AGGAAAGAGGGGAAACCACC

Downstream 100 bases:

>100_bases
ACAGCGCGGGTCTGTCCATAGCCCAAGCGGCGGCACCGGTCTTCATGGCCGGCGCTCCGCCCCGGAGCCGGCCCGCGCTG
GCGCCGGGCGTGGAACGCTA

Product: flavin-containing monooxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MSKRIAILGGGPSGLAVLRAFESARRKGAEIPEIVCYEKQSDCGGMWNYNWRTGLDEFGEPVHASMYRYLWSNGPKECLE
FADYSFEEHFGRPIPSFPPRAVLHDYIKGRIEKSNVRGYIKLNHAVRHVTYDAGTEKFLVTVKDLKADVLETSAFDYVVC
ATGHFSTPNVPYFEGVEAFPGRVLHAHDFRSADEFAGKNVLLIGASYSSEDIGIQCMKYGAKSVTFSYRTKAMGFDWPEG
FSEVPLLEKVVGKIAHFKDGTRKEVDAIVLCTGYLHHYPFLDDDLRLKSRNRLYPEGLYKGIFWVPNPRFMYVGAQDQFF
TFNMFDAQAWYARDVVLGRIPLPDAAAMEADIKGWVAKEEALEDASQMIDFQTEYVRELILATDYPRLDVDEVARMFKEW
EHHKVENILTYRDRSHRSTLTGTLAPKHHTPWMQALDDSLEAFLATMPSQAAE

Sequences:

>Translated_453_residues
MSKRIAILGGGPSGLAVLRAFESARRKGAEIPEIVCYEKQSDCGGMWNYNWRTGLDEFGEPVHASMYRYLWSNGPKECLE
FADYSFEEHFGRPIPSFPPRAVLHDYIKGRIEKSNVRGYIKLNHAVRHVTYDAGTEKFLVTVKDLKADVLETSAFDYVVC
ATGHFSTPNVPYFEGVEAFPGRVLHAHDFRSADEFAGKNVLLIGASYSSEDIGIQCMKYGAKSVTFSYRTKAMGFDWPEG
FSEVPLLEKVVGKIAHFKDGTRKEVDAIVLCTGYLHHYPFLDDDLRLKSRNRLYPEGLYKGIFWVPNPRFMYVGAQDQFF
TFNMFDAQAWYARDVVLGRIPLPDAAAMEADIKGWVAKEEALEDASQMIDFQTEYVRELILATDYPRLDVDEVARMFKEW
EHHKVENILTYRDRSHRSTLTGTLAPKHHTPWMQALDDSLEAFLATMPSQAAE
>Mature_452_residues
SKRIAILGGGPSGLAVLRAFESARRKGAEIPEIVCYEKQSDCGGMWNYNWRTGLDEFGEPVHASMYRYLWSNGPKECLEF
ADYSFEEHFGRPIPSFPPRAVLHDYIKGRIEKSNVRGYIKLNHAVRHVTYDAGTEKFLVTVKDLKADVLETSAFDYVVCA
TGHFSTPNVPYFEGVEAFPGRVLHAHDFRSADEFAGKNVLLIGASYSSEDIGIQCMKYGAKSVTFSYRTKAMGFDWPEGF
SEVPLLEKVVGKIAHFKDGTRKEVDAIVLCTGYLHHYPFLDDDLRLKSRNRLYPEGLYKGIFWVPNPRFMYVGAQDQFFT
FNMFDAQAWYARDVVLGRIPLPDAAAMEADIKGWVAKEEALEDASQMIDFQTEYVRELILATDYPRLDVDEVARMFKEWE
HHKVENILTYRDRSHRSTLTGTLAPKHHTPWMQALDDSLEAFLATMPSQAAE

Specific function: Unknown

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503759, Length=236, Percent_Identity=27.9661016949153, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI4503755, Length=221, Percent_Identity=29.8642533936652, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI4503757, Length=228, Percent_Identity=28.9473684210526, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI221316672, Length=236, Percent_Identity=30.0847457627119, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI221316674, Length=236, Percent_Identity=30.0847457627119, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI50541965, Length=249, Percent_Identity=30.1204819277108, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI50541961, Length=249, Percent_Identity=30.1204819277108, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI221316678, Length=236, Percent_Identity=30.0847457627119, Blast_Score=91, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17506045, Length=404, Percent_Identity=28.7128712871287, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI193202226, Length=386, Percent_Identity=28.4974093264249, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI25145785, Length=226, Percent_Identity=29.646017699115, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17555726, Length=235, Percent_Identity=25.9574468085106, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25150462, Length=239, Percent_Identity=26.3598326359833, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17561948, Length=235, Percent_Identity=25.531914893617, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17541300, Length=220, Percent_Identity=28.1818181818182, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6321970, Length=336, Percent_Identity=23.8095238095238, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19922866, Length=355, Percent_Identity=31.2676056338028, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI19921694, Length=388, Percent_Identity=27.5773195876289, Blast_Score=146, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: NA

Molecular weight: Translated: 51587; Mature: 51456

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRIAILGGGPSGLAVLRAFESARRKGAEIPEIVCYEKQSDCGGMWNYNWRTGLDEFGE
CCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHCC
PVHASMYRYLWSNGPKECLEFADYSFEEHFGRPIPSFPPRAVLHDYIKGRIEKSNVRGYI
HHHHHHHHHHHCCCHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHCCEECCCCCEEE
KLNHAVRHVTYDAGTEKFLVTVKDLKADVLETSAFDYVVCATGHFSTPNVPYFEGVEAFP
EECCEEEEEEECCCCCEEEEEHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCC
GRVLHAHDFRSADEFAGKNVLLIGASYSSEDIGIQCMKYGAKSVTFSYRTKAMGFDWPEG
CCEEEHHCCCCHHHHCCCCEEEEECCCCCCCCCHHHHHCCCCEEEEEEECCCCCCCCCCC
FSEVPLLEKVVGKIAHFKDGTRKEVDAIVLCTGYLHHYPFLDDDLRLKSRNRLYPEGLYK
CCCCHHHHHHHHHHHHCCCCCCHHHCEEEEEEHHHHHCCCCCCCCCCCCCCCCCHHHHCC
GIFWVPNPRFMYVGAQDQFFTFNMFDAQAWYARDVVLGRIPLPDAAAMEADIKGWVAKEE
CEEECCCCCEEEECCCCCEEEEEEECCCHHHHHCEEEECCCCCCHHHHHHHHHHHHHHHH
ALEDASQMIDFQTEYVRELILATDYPRLDVDEVARMFKEWEHHKVENILTYRDRSHRSTL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
TGTLAPKHHTPWMQALDDSLEAFLATMPSQAAE
EECCCCCCCCHHHHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure 
SKRIAILGGGPSGLAVLRAFESARRKGAEIPEIVCYEKQSDCGGMWNYNWRTGLDEFGE
CCEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHCC
PVHASMYRYLWSNGPKECLEFADYSFEEHFGRPIPSFPPRAVLHDYIKGRIEKSNVRGYI
HHHHHHHHHHHCCCHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHCCEECCCCCEEE
KLNHAVRHVTYDAGTEKFLVTVKDLKADVLETSAFDYVVCATGHFSTPNVPYFEGVEAFP
EECCEEEEEEECCCCCEEEEEHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCC
GRVLHAHDFRSADEFAGKNVLLIGASYSSEDIGIQCMKYGAKSVTFSYRTKAMGFDWPEG
CCEEEHHCCCCHHHHCCCCEEEEECCCCCCCCCHHHHHCCCCEEEEEEECCCCCCCCCCC
FSEVPLLEKVVGKIAHFKDGTRKEVDAIVLCTGYLHHYPFLDDDLRLKSRNRLYPEGLYK
CCCCHHHHHHHHHHHHCCCCCCHHHCEEEEEEHHHHHCCCCCCCCCCCCCCCCCHHHHCC
GIFWVPNPRFMYVGAQDQFFTFNMFDAQAWYARDVVLGRIPLPDAAAMEADIKGWVAKEE
CEEECCCCCEEEECCCCCEEEEEEECCCHHHHHCEEEECCCCCCHHHHHHHHHHHHHHHH
ALEDASQMIDFQTEYVRELILATDYPRLDVDEVARMFKEWEHHKVENILTYRDRSHRSTL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
TGTLAPKHHTPWMQALDDSLEAFLATMPSQAAE
EECCCCCCCCHHHHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]