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The map label for this gene is lysR [C]

Identifier: 158422960

GI number: 158422960

Start: 1500165

End: 1501094

Strand: Direct

Name: lysR [C]

Synonym: AZC_1336

Alternate gene names: 158422960

Gene position: 1500165-1501094 (Clockwise)

Preceding gene: 158422957

Following gene: 158422961

Centisome position: 27.94

GC content: 68.6

Gene sequence:

>930_bases
ATGGATCGCTTCGATGCCATGTCCGTGCTCCTGGCCGTCGTCGAGGCGGGCAGCCTTTCGGCCGGCGCCAGGCTCCTGCG
CGCGCCGCTTGCGACCGTCAGCCGGAAGATTGCTGAGCTGGAGCTTCATCTGGGAACGCCGCTGTTCGTCCGCAGCCGGC
GGGGGCTCGCCCTCACCGAGCCCGGCCGCGCGTTCGTTGCCGCCTCCCGGCGCATCCTGAGCCAGCTGGAGGAGGCGGAG
CGGGAGGCGGCCGGAGAATTCAGCACACCGCGAGGGACGCTGCATGTCACCGCGCCCATCTCCTTCGGTGAGCGTCATCT
CCTGCCCATCGCCCTCGAATTTCTCGCGGAACACCCTGAGATCAGCCTGCGCCTGACGTTGACCGACCGGCAGATCAGCC
TCGGAGACGAACACATCGACGTGGCGCTTCGGATCGGGCATCTGGAGGACAGCGCCCTCATCGCGACCCGCGTCGGCGCG
GTCCACCGGGTGATCTGCGCCAGCCCCGCTTATCTCGCGCGACGCGGCGTTCCCCGCCGGCCGGAGGATCTCGCCACCCA
TGAGGGCATCAGCTTCCAGGGCTTTGCGGTCGCGCCAGAGTGGCGTTACCGGCGGGACAGTGCGGCCTTTAGCATCGAGC
CGAGCCCGAAGCTCGCCGTAAACACCACGGAAGCCGCCATCCAGGCCGCCCGTGCCGGTCTCGGGATTATCCGCGTGCTC
TCCTATCAGGTGGCGGACGAACTGCGGTCCGGCGAATTGCAGGTCCTTCTGCCGGAGTCCGTGCCCGAGCCGCTGCCGGT
GAGCCTCATCTATCCGCAGGCGGATATGCTCCCGCTGAAGGTGCGCAGCTTCCTCGACTGGACCGTCCCGCGTCTGCGCG
CTCGCATGGCATCGCTCGATGCGGGCGAGCCCTACAGTGGCGGCCGGTAA

Upstream 100 bases:

>100_bases
CCCGACCTCGGCCCCGGTTGACGGTGACGTTAGGATATCCACTTATCGCGCGGTATTCTGGTTTTTCGGGAGCTATCCTC
CCAGATTTCGGTAGGTTGAG

Downstream 100 bases:

>100_bases
GCCGGGCGTTCGCCCCGTCGGGCGCCTTGTGACCGCGCGCAACCGTGGCTGAGGCGGTCACTTAGCTCTGTCAGCACACT
GACCTCGGGAGGGAGGTGCG

Product: transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MDRFDAMSVLLAVVEAGSLSAGARLLRAPLATVSRKIAELELHLGTPLFVRSRRGLALTEPGRAFVAASRRILSQLEEAE
REAAGEFSTPRGTLHVTAPISFGERHLLPIALEFLAEHPEISLRLTLTDRQISLGDEHIDVALRIGHLEDSALIATRVGA
VHRVICASPAYLARRGVPRRPEDLATHEGISFQGFAVAPEWRYRRDSAAFSIEPSPKLAVNTTEAAIQAARAGLGIIRVL
SYQVADELRSGELQVLLPESVPEPLPVSLIYPQADMLPLKVRSFLDWTVPRLRARMASLDAGEPYSGGR

Sequences:

>Translated_309_residues
MDRFDAMSVLLAVVEAGSLSAGARLLRAPLATVSRKIAELELHLGTPLFVRSRRGLALTEPGRAFVAASRRILSQLEEAE
REAAGEFSTPRGTLHVTAPISFGERHLLPIALEFLAEHPEISLRLTLTDRQISLGDEHIDVALRIGHLEDSALIATRVGA
VHRVICASPAYLARRGVPRRPEDLATHEGISFQGFAVAPEWRYRRDSAAFSIEPSPKLAVNTTEAAIQAARAGLGIIRVL
SYQVADELRSGELQVLLPESVPEPLPVSLIYPQADMLPLKVRSFLDWTVPRLRARMASLDAGEPYSGGR
>Mature_309_residues
MDRFDAMSVLLAVVEAGSLSAGARLLRAPLATVSRKIAELELHLGTPLFVRSRRGLALTEPGRAFVAASRRILSQLEEAE
REAAGEFSTPRGTLHVTAPISFGERHLLPIALEFLAEHPEISLRLTLTDRQISLGDEHIDVALRIGHLEDSALIATRVGA
VHRVICASPAYLARRGVPRRPEDLATHEGISFQGFAVAPEWRYRRDSAAFSIEPSPKLAVNTTEAAIQAARAGLGIIRVL
SYQVADELRSGELQVLLPESVPEPLPVSLIYPQADMLPLKVRSFLDWTVPRLRARMASLDAGEPYSGGR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=289, Percent_Identity=31.8339100346021, Blast_Score=160, Evalue=8e-41,
Organism=Escherichia coli, GI145693193, Length=299, Percent_Identity=34.1137123745819, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1786401, Length=284, Percent_Identity=32.0422535211268, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789440, Length=297, Percent_Identity=28.2828282828283, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787128, Length=283, Percent_Identity=25.7950530035336, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87081978, Length=272, Percent_Identity=27.9411764705882, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1787589, Length=272, Percent_Identity=27.9411764705882, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789173, Length=288, Percent_Identity=26.3888888888889, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33706; Mature: 33706

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRFDAMSVLLAVVEAGSLSAGARLLRAPLATVSRKIAELELHLGTPLFVRSRRGLALTE
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEECCCCEEEEC
PGRAFVAASRRILSQLEEAEREAAGEFSTPRGTLHVTAPISFGERHLLPIALEFLAEHPE
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCC
ISLRLTLTDRQISLGDEHIDVALRIGHLEDSALIATRVGAVHRVICASPAYLARRGVPRR
EEEEEEEECCEEECCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCC
PEDLATHEGISFQGFAVAPEWRYRRDSAAFSIEPSPKLAVNTTEAAIQAARAGLGIIRVL
CHHHHHCCCCCCCEEEECCCCCCCCCCCEEEECCCCCEEEEHHHHHHHHHHHCHHHHHHH
SYQVADELRSGELQVLLPESVPEPLPVSLIYPQADMLPLKVRSFLDWTVPRLRARMASLD
HHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
AGEPYSGGR
CCCCCCCCC
>Mature Secondary Structure
MDRFDAMSVLLAVVEAGSLSAGARLLRAPLATVSRKIAELELHLGTPLFVRSRRGLALTE
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEECCCCEEEEC
PGRAFVAASRRILSQLEEAEREAAGEFSTPRGTLHVTAPISFGERHLLPIALEFLAEHPE
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCC
ISLRLTLTDRQISLGDEHIDVALRIGHLEDSALIATRVGAVHRVICASPAYLARRGVPRR
EEEEEEEECCEEECCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCC
PEDLATHEGISFQGFAVAPEWRYRRDSAAFSIEPSPKLAVNTTEAAIQAARAGLGIIRVL
CHHHHHCCCCCCCEEEECCCCCCCCCCCEEEECCCCCEEEEHHHHHHHHHHHCHHHHHHH
SYQVADELRSGELQVLLPESVPEPLPVSLIYPQADMLPLKVRSFLDWTVPRLRARMASLD
HHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
AGEPYSGGR
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]