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The map label for this gene is lysR [H]

Identifier: 158422940

GI number: 158422940

Start: 1474238

End: 1475140

Strand: Direct

Name: lysR [H]

Synonym: AZC_1316

Alternate gene names: 158422940

Gene position: 1474238-1475140 (Clockwise)

Preceding gene: 158422937

Following gene: 158422948

Centisome position: 27.45

GC content: 64.23

Gene sequence:

>903_bases
GTGGCCTTCGATAGTCGCTTGTTGAATGGGATCGGCGTGGTTTCGGCCGTTGTTGAAGCTGGCAGCTTCGCGCGCGCGGG
CGAAGCGCTGGGGCTGACGCAACCCGCCGTCAGCCGCGCCGTAGCCCGTCTGGAACAGCGGATCGGCATTCGGATCTTCA
ATCGGACGGCGCGGTCCATTTCGCTGACCGACGAAGGCCGGCGGTATTACGAGGCGGTTGCGCCTCTCATTGCAGGCATT
GAAGACGCCACCCTGAGCGCCGGCCGCGCCAAGGCGCTGGTTCGCGGGCGGCTGAGGGTGAATGTGGACGGCGCCTTTGG
GCATTTCGTGCTCACGCGACGGCTCGGCGCGTTCCTGGACCAGTATCCGGATCTGGCGGTCGACGTGGCAGTGCGCGACG
CTATGGGCGATCTCGTCGGGGATGGTTTCGATGTCGCCGTCCGTTTCGGGTATCCGGAGCCCTCCAACCTCAGAGCGGAG
CTTTTGCTGGAGACGCGCGTGCTGACGTGCGCGTCCGCAAGCTATATCGCCCGTTACGGAGCGCCGTCTCACCCGCGAGA
TCTGGTGAATGGCCACCAGTGCGTTCTTCTGCGCGATCCCTCGACGGGACGTCCATACGAATGGGAGTTCAGCCGGGGAG
GCGAGACCATCCCGTTCCAGGCAAGCGGGCGCCTCATGGTCCATGACACCGGCTCGCTGATCGGCGGGTGCCTCGGCGGC
ATCGGGATGGCGCAACTGCTCGAGCTCTATGCAGAGAACTTGCTCGGGGAGGGAAAACTCGTGCAGATGCTGCCCGAGTG
GTCGGACGAAACCTTTCCCCTCTACGCCTATCATCGTGCGTCCAACCTCGTGTCTGCCAAGGTCAGCGCGTTTCTCTCCT
TCGTGCGGCAGATCACGAGGTAA

Upstream 100 bases:

>100_bases
GTGCCCTTTCCAACGAATGGCTCGATGGCAGGAGTACCCCTCTTGTCACCCGCATAAAAATGCATACTGATCAGGGAAAG
AATGACTGAAAGTATGGCTC

Downstream 100 bases:

>100_bases
TCCGCCAACGTGCGCAACGCGAGCAGGGCGGCGGCGCGGAACGTTTGCCCATGCGCTGCCCTGGACGGCCCGCAGGCGCC
GAGGCGATAGCCGGCCGTGG

Product: regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MAFDSRLLNGIGVVSAVVEAGSFARAGEALGLTQPAVSRAVARLEQRIGIRIFNRTARSISLTDEGRRYYEAVAPLIAGI
EDATLSAGRAKALVRGRLRVNVDGAFGHFVLTRRLGAFLDQYPDLAVDVAVRDAMGDLVGDGFDVAVRFGYPEPSNLRAE
LLLETRVLTCASASYIARYGAPSHPRDLVNGHQCVLLRDPSTGRPYEWEFSRGGETIPFQASGRLMVHDTGSLIGGCLGG
IGMAQLLELYAENLLGEGKLVQMLPEWSDETFPLYAYHRASNLVSAKVSAFLSFVRQITR

Sequences:

>Translated_300_residues
MAFDSRLLNGIGVVSAVVEAGSFARAGEALGLTQPAVSRAVARLEQRIGIRIFNRTARSISLTDEGRRYYEAVAPLIAGI
EDATLSAGRAKALVRGRLRVNVDGAFGHFVLTRRLGAFLDQYPDLAVDVAVRDAMGDLVGDGFDVAVRFGYPEPSNLRAE
LLLETRVLTCASASYIARYGAPSHPRDLVNGHQCVLLRDPSTGRPYEWEFSRGGETIPFQASGRLMVHDTGSLIGGCLGG
IGMAQLLELYAENLLGEGKLVQMLPEWSDETFPLYAYHRASNLVSAKVSAFLSFVRQITR
>Mature_299_residues
AFDSRLLNGIGVVSAVVEAGSFARAGEALGLTQPAVSRAVARLEQRIGIRIFNRTARSISLTDEGRRYYEAVAPLIAGIE
DATLSAGRAKALVRGRLRVNVDGAFGHFVLTRRLGAFLDQYPDLAVDVAVRDAMGDLVGDGFDVAVRFGYPEPSNLRAEL
LLETRVLTCASASYIARYGAPSHPRDLVNGHQCVLLRDPSTGRPYEWEFSRGGETIPFQASGRLMVHDTGSLIGGCLGGI
GMAQLLELYAENLLGEGKLVQMLPEWSDETFPLYAYHRASNLVSAKVSAFLSFVRQITR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787128, Length=290, Percent_Identity=32.4137931034483, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1786401, Length=291, Percent_Identity=29.8969072164948, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789639, Length=287, Percent_Identity=27.5261324041812, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI145693193, Length=289, Percent_Identity=25.2595155709343, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789440, Length=291, Percent_Identity=27.1477663230241, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI87081978, Length=292, Percent_Identity=29.1095890410959, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1787589, Length=266, Percent_Identity=26.3157894736842, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789173, Length=256, Percent_Identity=29.6875, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788706, Length=310, Percent_Identity=24.5161290322581, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786448, Length=261, Percent_Identity=26.0536398467433, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI157672245, Length=171, Percent_Identity=28.6549707602339, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789204, Length=127, Percent_Identity=29.9212598425197, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788748, Length=118, Percent_Identity=30.5084745762712, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32533; Mature: 32401

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFDSRLLNGIGVVSAVVEAGSFARAGEALGLTQPAVSRAVARLEQRIGIRIFNRTARSI
CCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCEE
SLTDEGRRYYEAVAPLIAGIEDATLSAGRAKALVRGRLRVNVDGAFGHFVLTRRLGAFLD
EECHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHH
QYPDLAVDVAVRDAMGDLVGDGFDVAVRFGYPEPSNLRAELLLETRVLTCASASYIARYG
HCCCCEEHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
APSHPRDLVNGHQCVLLRDPSTGRPYEWEFSRGGETIPFQASGRLMVHDTGSLIGGCLGG
CCCCCHHHCCCCEEEEEECCCCCCCEEEEECCCCCCCEEECCCEEEEEECHHHHHHHHHH
IGMAQLLELYAENLLGEGKLVQMLPEWSDETFPLYAYHRASNLVSAKVSAFLSFVRQITR
HHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AFDSRLLNGIGVVSAVVEAGSFARAGEALGLTQPAVSRAVARLEQRIGIRIFNRTARSI
CCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCEE
SLTDEGRRYYEAVAPLIAGIEDATLSAGRAKALVRGRLRVNVDGAFGHFVLTRRLGAFLD
EECHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHH
QYPDLAVDVAVRDAMGDLVGDGFDVAVRFGYPEPSNLRAELLLETRVLTCASASYIARYG
HCCCCEEHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
APSHPRDLVNGHQCVLLRDPSTGRPYEWEFSRGGETIPFQASGRLMVHDTGSLIGGCLGG
CCCCCHHHCCCCEEEEEECCCCCCCEEEEECCCCCCCEEECCCEEEEEECHHHHHHHHHH
IGMAQLLELYAENLLGEGKLVQMLPEWSDETFPLYAYHRASNLVSAKVSAFLSFVRQITR
HHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]