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The map label for this gene is mas [H]

Identifier: 158422937

GI number: 158422937

Start: 1470821

End: 1471807

Strand: Direct

Name: mas [H]

Synonym: AZC_1313

Alternate gene names: 158422937

Gene position: 1470821-1471807 (Clockwise)

Preceding gene: 158422936

Following gene: 158422940

Centisome position: 27.39

GC content: 64.54

Gene sequence:

>987_bases
GTGAAGGCTGTTATCTATGATGCCTTTGGTCCGGCGGATGTTCTCCGCCTGGCCGAGGTGCCGATGCCCGAGGTGCGCCC
GCGCGATCTTCTGGTCAAGGTGCACGCGGCCGGCGTCAATCGCGCCGATCTGCTGCAGCGGCAGGGCTATTACGGACGTC
AGAGTTATGGCGAGAGCGATCTGCTCGGATTGGAGGTGGCCGGCGAAGTCGTGGCGGTAGGCCATGAGGTCACCGACATC
GAGCCGGGTGAGCCTGTGATGGCGATCGTCGGTGGAGGCGCCTACGCCGAATTCGCCCGCGTGGACCGGGGATTGGCGGT
GCGCATTCCGCCTGCGCTCGACTTTACGGGTGCCGCGGCGGTGATGGAATCCTTCGTCACTGCCTGGGAGGCCGCTGTGC
ATCTGGGCGGGACCGGCGCCGTGACGACGGTGCTCGTCCACGCAGCCGCCGGCGGTGTCGGTTCCGCCGGCGTCGAGATC
GCTCATTCTCTCGGCGCCCGTGTCTTCGCGACGGCCAATGCCCAGCGCCGCACGGACATTCTGAACCTCGGCGCGGAATG
CGTGTTCGACTACCGGTCCGAGGATTTTGAACAGGGCGTGCGGGCGGCGACCCAAGGACAAGGGGTGGATGTGATCATCG
ACTTCGTCGGCGGCGATTATCTCGCCCGCAACCTCCGCAGTCTCGCGCTAGGCGGCCGTCTTGTTCAGGTGGGGCTGCTG
GGCGGGAAGGACACGGCGGAGCTTCCGCTCTCCGTCCTGCTGCATAACCATCTGCGCATTATCGGCACCGTCATGAAATC
GCGTGACGCGGAGGAAAAGCGAGCCATGGTCCGGCGCTTCGCGGAAAACGCGCTGCCGATGTTTACGGATGGCCGGCTGA
AGCCTTTGGTCGGCGAGGTATTTCCGCTGTCCGAAGCCGCCAATGCACATCGCTGCATGGAAGCGGGCGGTGGATTCGGA
AAGATCGTATTGAAGGTCTCACCTTAA

Upstream 100 bases:

>100_bases
CGATCGCCCGCCAGGAAGCAGGCGGCGATCACAACCGGCGGGAAACGCCGCTTTTCGCCGCGAGCATCGGCCGACGCGCC
ATGGCAAAGGCAGCCGCCAA

Downstream 100 bases:

>100_bases
CCCGCCTGCATCGCAGCGCCCTGCGACGCGCGACCCGCTCGGGCAGACGGGCAGATAGGTCATCGCCCGCTTTCCGGGGT
GAGCGCCTGCGCCCGGCGCG

Product: zinc-containing alcohol dehydrogenase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MKAVIYDAFGPADVLRLAEVPMPEVRPRDLLVKVHAAGVNRADLLQRQGYYGRQSYGESDLLGLEVAGEVVAVGHEVTDI
EPGEPVMAIVGGGAYAEFARVDRGLAVRIPPALDFTGAAAVMESFVTAWEAAVHLGGTGAVTTVLVHAAAGGVGSAGVEI
AHSLGARVFATANAQRRTDILNLGAECVFDYRSEDFEQGVRAATQGQGVDVIIDFVGGDYLARNLRSLALGGRLVQVGLL
GGKDTAELPLSVLLHNHLRIIGTVMKSRDAEEKRAMVRRFAENALPMFTDGRLKPLVGEVFPLSEAANAHRCMEAGGGFG
KIVLKVSP

Sequences:

>Translated_328_residues
MKAVIYDAFGPADVLRLAEVPMPEVRPRDLLVKVHAAGVNRADLLQRQGYYGRQSYGESDLLGLEVAGEVVAVGHEVTDI
EPGEPVMAIVGGGAYAEFARVDRGLAVRIPPALDFTGAAAVMESFVTAWEAAVHLGGTGAVTTVLVHAAAGGVGSAGVEI
AHSLGARVFATANAQRRTDILNLGAECVFDYRSEDFEQGVRAATQGQGVDVIIDFVGGDYLARNLRSLALGGRLVQVGLL
GGKDTAELPLSVLLHNHLRIIGTVMKSRDAEEKRAMVRRFAENALPMFTDGRLKPLVGEVFPLSEAANAHRCMEAGGGFG
KIVLKVSP
>Mature_328_residues
MKAVIYDAFGPADVLRLAEVPMPEVRPRDLLVKVHAAGVNRADLLQRQGYYGRQSYGESDLLGLEVAGEVVAVGHEVTDI
EPGEPVMAIVGGGAYAEFARVDRGLAVRIPPALDFTGAAAVMESFVTAWEAAVHLGGTGAVTTVLVHAAAGGVGSAGVEI
AHSLGARVFATANAQRRTDILNLGAECVFDYRSEDFEQGVRAATQGQGVDVIIDFVGGDYLARNLRSLALGGRLVQVGLL
GGKDTAELPLSVLLHNHLRIIGTVMKSRDAEEKRAMVRRFAENALPMFTDGRLKPLVGEVFPLSEAANAHRCMEAGGGFG
KIVLKVSP

Specific function: Catalyzes the elongation of N-fatty acyl-CoA with methylamalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=331, Percent_Identity=38.0664652567976, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI22538444, Length=331, Percent_Identity=38.0664652567976, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI194239674, Length=333, Percent_Identity=32.1321321321321, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI13236495, Length=333, Percent_Identity=32.1321321321321, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI18379349, Length=313, Percent_Identity=28.7539936102236, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI24308257, Length=344, Percent_Identity=27.6162790697674, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI194239676, Length=333, Percent_Identity=29.1291291291291, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI47519420, Length=371, Percent_Identity=26.9541778975741, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI41872631, Length=312, Percent_Identity=26.9230769230769, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI197927207, Length=184, Percent_Identity=30.4347826086957, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI28557745, Length=228, Percent_Identity=28.9473684210526, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI67078404, Length=319, Percent_Identity=26.0188087774295, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1790485, Length=330, Percent_Identity=30, Blast_Score=88, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17507255, Length=329, Percent_Identity=26.7477203647416, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI212642053, Length=278, Percent_Identity=29.4964028776978, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71987554, Length=359, Percent_Identity=26.7409470752089, Blast_Score=87, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6319520, Length=336, Percent_Identity=26.1904761904762, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24581345, Length=274, Percent_Identity=29.1970802919708, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI221330659, Length=306, Percent_Identity=28.1045751633987, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI19920632, Length=306, Percent_Identity=28.1045751633987, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR013968
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00107 ADH_zinc_N; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: =2.3.1.111 [H]

Molecular weight: Translated: 34620; Mature: 34620

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVIYDAFGPADVLRLAEVPMPEVRPRDLLVKVHAAGVNRADLLQRQGYYGRQSYGESD
CCEEEEECCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCCC
LLGLEVAGEVVAVGHEVTDIEPGEPVMAIVGGGAYAEFARVDRGLAVRIPPALDFTGAAA
EEEHEECCCEEEECCEECCCCCCCCEEEEECCCHHHHHHHHCCCCEEECCCCCCCCHHHH
VMESFVTAWEAAVHLGGTGAVTTVLVHAAAGGVGSAGVEIAHSLGARVFATANAQRRTDI
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEECCCHHHHHH
LNLGAECVFDYRSEDFEQGVRAATQGQGVDVIIDFVGGDYLARNLRSLALGGRLVQVGLL
HHCCHHHEECCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCEEEEEEEE
GGKDTAELPLSVLLHNHLRIIGTVMKSRDAEEKRAMVRRFAENALPMFTDGRLKPLVGEV
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
FPLSEAANAHRCMEAGGGFGKIVLKVSP
CCCHHHHHHHHHHHCCCCEEEEEEEECC
>Mature Secondary Structure
MKAVIYDAFGPADVLRLAEVPMPEVRPRDLLVKVHAAGVNRADLLQRQGYYGRQSYGESD
CCEEEEECCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCCC
LLGLEVAGEVVAVGHEVTDIEPGEPVMAIVGGGAYAEFARVDRGLAVRIPPALDFTGAAA
EEEHEECCCEEEECCEECCCCCCCCEEEEECCCHHHHHHHHCCCCEEECCCCCCCCHHHH
VMESFVTAWEAAVHLGGTGAVTTVLVHAAAGGVGSAGVEIAHSLGARVFATANAQRRTDI
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEECCCHHHHHH
LNLGAECVFDYRSEDFEQGVRAATQGQGVDVIIDFVGGDYLARNLRSLALGGRLVQVGLL
HHCCHHHEECCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCEEEEEEEE
GGKDTAELPLSVLLHNHLRIIGTVMKSRDAEEKRAMVRRFAENALPMFTDGRLKPLVGEV
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
FPLSEAANAHRCMEAGGGFGKIVLKVSP
CCCHHHHHHHHHHHCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1527058; 12788972 [H]