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The map label for this gene is cph2 [H]

Identifier: 158422834

GI number: 158422834

Start: 1352329

End: 1353873

Strand: Reverse

Name: cph2 [H]

Synonym: AZC_1210

Alternate gene names: 158422834

Gene position: 1353873-1352329 (Counterclockwise)

Preceding gene: 158422835

Following gene: 158422833

Centisome position: 25.21

GC content: 69.77

Gene sequence:

>1545_bases
ATGATCAAGCCTGGCAGCACTGCACTCAAGGCAGCGCCTCCGTCGGTCGTTCCGCCGGCAGCGCGGCTGATGATTCCTGC
GGGCGCGCTGATCTCGGTGATCTTTGCCAGCTTCATGGCGCTCACCCTCTGGCAGAATTACGGGGATGTGGCCCGGGAGG
CGGCGAGCCACGGCGAACAGCGGGTGGACAGCCTCGCCCGCGACGTGGCGGGGCAGATCTTCCCCTATCGCGTCCTGCTG
CGGCAGGTGGCCGCGGACTATGCCGATCCGCAGACGGACCAGACGCCGGCCGGCTGGCAGCGGCTGCTGGCACGCATGAT
TTCCGCCACCGAACGCTCCGGCGTGATGCTTCTGACCGATGCCTCCGGGCAGGTGGTGGCCCGCTCCGACCGCCCCGCCG
GCCCTGGCGAGCGGGTTCGGACGCAACCCTATTTCGCCCTCCATGCCAAAGGTCAGGTGGACGGTCCCTATCTCAGCGAG
CGGGTGGCCTGTGACGGCACAGAGCCCTGCATCGCCCTGTCGCAGGCCCTGAAAGATCCGGACGGCCAGTTTGCGGGCGT
GGCCGCCGTCCTGCTGCCCCTCTCCCTCCTGCGCGAACCGCTGAAGGCGGAGGCTGCGGAGACCAGCGACCCCATGCTGG
TCGCGCGCATCGACGGCACGCTGTTCGTGGAAGAGTGCGGCACCTCCGGCATCTGCATCCGACCGCCGCCCGACCTGATC
CGCGAGATTGCGGGGGCGGTCCACGCGCCCGTGACCCTGTCCTATGGCGACGGCAAGCGGACCTTCTATGCGGCGCCCGT
GCCGCAACTGCCGCTGGTGGTGGCCACCGGCCAGTCGATCCGCGACATCTTCCTGCCTTGGCGCTACCGCGTGCTGGTCG
GCACCGCGGCCGTTCTCACCGTGGGCTTCGCCTCCATCGCCATCGCCCTCGTGCTGCGGCACGACCTGATGCGCCGCAGC
CGCCTCCAGGCGGAACTGCTCCAGCTCTCCCTGACCGACGATCTGACGGGCATCGCCAACCGCCGGCGCTTCTTCGATGT
GGCCATCCGGGAATGGCAGCGGGCGCAGCGGCTCGGCTCGCCGGTGGCCGTGCTGATGATCGACATCGACCGGTTCAAGC
TGCTGAACGACCGCCTCGGCCATGCGGCGGGCGATGCCGTGCTCCAGGCCATCGCCCAGCTCATCCGCCACAGCCTGCGC
CGGCCGGCGGATCTCGCCGCCCGTTACGGCGGCGAGGAGTTCACCGCCATCCTGCCCGACACCGACATGGCCGGCGCCTT
CCAGACGGCGGAGCGCATCCGCACGCAGGTGGAGCGGGACGTGATCCGCGGCGACCATCCGGTCACCGTCAGCATCGGCA
TTGCCGCCGCCATCGCCTCTCCGAACGAGACGTTCGAAAATGTGGTCGCCGCCGCCGACCGCGCCCTCTACCGGGCCAAG
GAGAGCGGACGCAATCGCGTGATGGTCGAACGCATCGGGGATGCGCACGTCGCCGTGCCGGAGCCCCATTTCTCAGACGC
CACGCTCGATCCGACGCGCGCCTGA

Upstream 100 bases:

>100_bases
CATTTCGACAGATAGACGTTAACCCTGTCGTAAGCCTGCAACCTACCGATCGGCACGGCGCCCGTTCGCGCCGCGCGAGG
CCCCTGGACCCGTCCGCCGC

Downstream 100 bases:

>100_bases
CCCGCACGGACGTTCCTCCCGCGGATCCTGCGGAGATTTTCACCCGCCGGGGTGCTGCGATATGATCGCTCCATGAGCCG
ACCGCGCGAGCCCTTTGTCG

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MIKPGSTALKAAPPSVVPPAARLMIPAGALISVIFASFMALTLWQNYGDVAREAASHGEQRVDSLARDVAGQIFPYRVLL
RQVAADYADPQTDQTPAGWQRLLARMISATERSGVMLLTDASGQVVARSDRPAGPGERVRTQPYFALHAKGQVDGPYLSE
RVACDGTEPCIALSQALKDPDGQFAGVAAVLLPLSLLREPLKAEAAETSDPMLVARIDGTLFVEECGTSGICIRPPPDLI
REIAGAVHAPVTLSYGDGKRTFYAAPVPQLPLVVATGQSIRDIFLPWRYRVLVGTAAVLTVGFASIAIALVLRHDLMRRS
RLQAELLQLSLTDDLTGIANRRRFFDVAIREWQRAQRLGSPVAVLMIDIDRFKLLNDRLGHAAGDAVLQAIAQLIRHSLR
RPADLAARYGGEEFTAILPDTDMAGAFQTAERIRTQVERDVIRGDHPVTVSIGIAAAIASPNETFENVVAAADRALYRAK
ESGRNRVMVERIGDAHVAVPEPHFSDATLDPTRA

Sequences:

>Translated_514_residues
MIKPGSTALKAAPPSVVPPAARLMIPAGALISVIFASFMALTLWQNYGDVAREAASHGEQRVDSLARDVAGQIFPYRVLL
RQVAADYADPQTDQTPAGWQRLLARMISATERSGVMLLTDASGQVVARSDRPAGPGERVRTQPYFALHAKGQVDGPYLSE
RVACDGTEPCIALSQALKDPDGQFAGVAAVLLPLSLLREPLKAEAAETSDPMLVARIDGTLFVEECGTSGICIRPPPDLI
REIAGAVHAPVTLSYGDGKRTFYAAPVPQLPLVVATGQSIRDIFLPWRYRVLVGTAAVLTVGFASIAIALVLRHDLMRRS
RLQAELLQLSLTDDLTGIANRRRFFDVAIREWQRAQRLGSPVAVLMIDIDRFKLLNDRLGHAAGDAVLQAIAQLIRHSLR
RPADLAARYGGEEFTAILPDTDMAGAFQTAERIRTQVERDVIRGDHPVTVSIGIAAAIASPNETFENVVAAADRALYRAK
ESGRNRVMVERIGDAHVAVPEPHFSDATLDPTRA
>Mature_514_residues
MIKPGSTALKAAPPSVVPPAARLMIPAGALISVIFASFMALTLWQNYGDVAREAASHGEQRVDSLARDVAGQIFPYRVLL
RQVAADYADPQTDQTPAGWQRLLARMISATERSGVMLLTDASGQVVARSDRPAGPGERVRTQPYFALHAKGQVDGPYLSE
RVACDGTEPCIALSQALKDPDGQFAGVAAVLLPLSLLREPLKAEAAETSDPMLVARIDGTLFVEECGTSGICIRPPPDLI
REIAGAVHAPVTLSYGDGKRTFYAAPVPQLPLVVATGQSIRDIFLPWRYRVLVGTAAVLTVGFASIAIALVLRHDLMRRS
RLQAELLQLSLTDDLTGIANRRRFFDVAIREWQRAQRLGSPVAVLMIDIDRFKLLNDRLGHAAGDAVLQAIAQLIRHSLR
RPADLAARYGGEEFTAILPDTDMAGAFQTAERIRTQVERDVIRGDHPVTVSIGIAAAIASPNETFENVVAAADRALYRAK
ESGRNRVMVERIGDAHVAVPEPHFSDATLDPTRA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI87081881, Length=181, Percent_Identity=39.2265193370166, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787262, Length=167, Percent_Identity=43.7125748502994, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI145693134, Length=157, Percent_Identity=38.8535031847134, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI87082007, Length=199, Percent_Identity=38.1909547738693, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1787802, Length=220, Percent_Identity=32.7272727272727, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1786584, Length=173, Percent_Identity=31.7919075144509, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1787816, Length=162, Percent_Identity=36.4197530864198, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788085, Length=173, Percent_Identity=34.6820809248555, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788381, Length=204, Percent_Identity=34.8039215686275, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI87081974, Length=181, Percent_Identity=32.5966850828729, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI87081977, Length=183, Percent_Identity=29.5081967213115, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788956, Length=169, Percent_Identity=34.3195266272189, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787541, Length=177, Percent_Identity=31.638418079096, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 55540; Mature: 55540

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKPGSTALKAAPPSVVPPAARLMIPAGALISVIFASFMALTLWQNYGDVAREAASHGEQ
CCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVDSLARDVAGQIFPYRVLLRQVAADYADPQTDQTPAGWQRLLARMISATERSGVMLLTD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEC
ASGQVVARSDRPAGPGERVRTQPYFALHAKGQVDGPYLSERVACDGTEPCIALSQALKDP
CCCCEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHCCC
DGQFAGVAAVLLPLSLLREPLKAEAAETSDPMLVARIDGTLFVEECGTSGICIRPPPDLI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEECCCCCCEEECCCHHHH
REIAGAVHAPVTLSYGDGKRTFYAAPVPQLPLVVATGQSIRDIFLPWRYRVLVGTAAVLT
HHHHHHHCCCEEEEECCCCEEEEECCCCCCCEEEECCCHHHHHHCCHHHHHHHHHHHHHH
VGFASIAIALVLRHDLMRRSRLQAELLQLSLTDDLTGIANRRRFFDVAIREWQRAQRLGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PVAVLMIDIDRFKLLNDRLGHAAGDAVLQAIAQLIRHSLRRPADLAARYGGEEFTAILPD
CEEEEEEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEECCC
TDMAGAFQTAERIRTQVERDVIRGDHPVTVSIGIAAAIASPNETFENVVAAADRALYRAK
CCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
ESGRNRVMVERIGDAHVAVPEPHFSDATLDPTRA
HCCCCEEEEEECCCCEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIKPGSTALKAAPPSVVPPAARLMIPAGALISVIFASFMALTLWQNYGDVAREAASHGEQ
CCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVDSLARDVAGQIFPYRVLLRQVAADYADPQTDQTPAGWQRLLARMISATERSGVMLLTD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEC
ASGQVVARSDRPAGPGERVRTQPYFALHAKGQVDGPYLSERVACDGTEPCIALSQALKDP
CCCCEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHCCC
DGQFAGVAAVLLPLSLLREPLKAEAAETSDPMLVARIDGTLFVEECGTSGICIRPPPDLI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEECCCCCCEEECCCHHHH
REIAGAVHAPVTLSYGDGKRTFYAAPVPQLPLVVATGQSIRDIFLPWRYRVLVGTAAVLT
HHHHHHHCCCEEEEECCCCEEEEECCCCCCCEEEECCCHHHHHHCCHHHHHHHHHHHHHH
VGFASIAIALVLRHDLMRRSRLQAELLQLSLTDDLTGIANRRRFFDVAIREWQRAQRLGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PVAVLMIDIDRFKLLNDRLGHAAGDAVLQAIAQLIRHSLRRPADLAARYGGEEFTAILPD
CEEEEEEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEECCC
TDMAGAFQTAERIRTQVERDVIRGDHPVTVSIGIAAAIASPNETFENVVAAADRALYRAK
CCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
ESGRNRVMVERIGDAHVAVPEPHFSDATLDPTRA
HCCCCEEEEEECCCCEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]