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The map label for this gene is chaA [C]

Identifier: 158422831

GI number: 158422831

Start: 1349081

End: 1350145

Strand: Direct

Name: chaA [C]

Synonym: AZC_1207

Alternate gene names: 158422831

Gene position: 1349081-1350145 (Clockwise)

Preceding gene: 158422830

Following gene: 158422832

Centisome position: 25.12

GC content: 66.48

Gene sequence:

>1065_bases
ATGCCGTTCATCTGGCTCGCTTATTTCTTTCCCCTCGCCGCGCTCGCCCTCGGCCTTGCCGTTTCCGTCCTGCCCGTCCC
TTTCACGGGGGGCCTGTCCTTCATCGAGACGGTGCTCCTCATCGGCACCTCCTTTGCGGCGGTCCACCATGCGGAGGGCA
TCTCGTCCCGGATCGGCCAGCCCTTCGGCACGCTGATCCTGACCCTGAGCGTCACCGTCATCGAGGTCTCGGTGCTTGTG
GCCATGATGCTGAACGGCGAGAACAATCCCGGCGTCGGCCGGGAGGCCGTGCTCTCCACCGTCATGTTCGTCTGCACGGG
GGTCGTGGGCGCCTGCCTGCTGGTGGGTGCGCTCCGCCACCGGGAGCAGGAGGTGCGCCAGCAGGGCGTGAACGGCTATC
TTTCGGTCATCATCGCCATTTCGGTGCTGTGCCTGCTGCTGCCGCAAAACACCCACGCCGGCCTGATGGGTGCGGTGGAT
CCGTTCCAGATTTCCTTCATCATGTGCGGCACGGTGGTGCTCTACGGCGCCTTCCTCTTCATGCAGACGGTGCGCCACCG
GGCGGACTTCATGCCGGAGGCGAGCGAGCCCGCCCCGGCGCGGCCGCGCCGTCTCGTGGTGCATATCCCGCTGCTGCTGG
CGGCGCTCGGGGGCATCGTTCTTGTCTCGAGCGGGGTAGCTGCCGGCGTCGAGGAACTGCTCGACCGGCTGCATCTGCGC
GATCCGGATGCCGTCATCAGCGCCGCCGTGGTGGCGATGCTGCTGCTGCCGGAGACCATCACCGCCATCCGCGCCGCCCG
CGCCAACGATCTTCAGCGCAGCATCAACACGGCGCTCGGCTCGGCCCTTGCCACCATCGGCCTCACCATGCCGGCCATGG
TGGCGATCAGCGTCTGGGTGGATCGTCCCATCTATCTGGGCATCGAGCCGGAGGACCGGGTGCAGTTGCTGCTGGTGCTG
GTGCTGTCCATCGTCAGCTTCGGCACCGGGCGCACCAACCTGCTCAACGGCTTCGTGCATCTCGTGCTGTTCGCCATCTA
TGTGATGACGTTGTTCGTGCCGTGA

Upstream 100 bases:

>100_bases
GGGCTTTCACCCGGCCGGCCAGGCGCGATTATCCGGGCGAACGGCGGCGGGGCAGGGCGCGCGCCAGAGCGCGCATGCGC
GGGATTCTTCGGGGATTTTC

Downstream 100 bases:

>100_bases
GCCGGCGAAGCGGCCGTCCACATTGGCGGATGTTCGGGTGGACACCGCGGCGGCACGGTGGCATGTTCCGCCCGACCAAG
AAGAGGCTCGCTCCGTGAAA

Product: Ca2+/H+ antiporter

Products: Na (I) [Periplasm]; Ca (II) [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MPFIWLAYFFPLAALALGLAVSVLPVPFTGGLSFIETVLLIGTSFAAVHHAEGISSRIGQPFGTLILTLSVTVIEVSVLV
AMMLNGENNPGVGREAVLSTVMFVCTGVVGACLLVGALRHREQEVRQQGVNGYLSVIIAISVLCLLLPQNTHAGLMGAVD
PFQISFIMCGTVVLYGAFLFMQTVRHRADFMPEASEPAPARPRRLVVHIPLLLAALGGIVLVSSGVAAGVEELLDRLHLR
DPDAVISAAVVAMLLLPETITAIRAARANDLQRSINTALGSALATIGLTMPAMVAISVWVDRPIYLGIEPEDRVQLLLVL
VLSIVSFGTGRTNLLNGFVHLVLFAIYVMTLFVP

Sequences:

>Translated_354_residues
MPFIWLAYFFPLAALALGLAVSVLPVPFTGGLSFIETVLLIGTSFAAVHHAEGISSRIGQPFGTLILTLSVTVIEVSVLV
AMMLNGENNPGVGREAVLSTVMFVCTGVVGACLLVGALRHREQEVRQQGVNGYLSVIIAISVLCLLLPQNTHAGLMGAVD
PFQISFIMCGTVVLYGAFLFMQTVRHRADFMPEASEPAPARPRRLVVHIPLLLAALGGIVLVSSGVAAGVEELLDRLHLR
DPDAVISAAVVAMLLLPETITAIRAARANDLQRSINTALGSALATIGLTMPAMVAISVWVDRPIYLGIEPEDRVQLLLVL
VLSIVSFGTGRTNLLNGFVHLVLFAIYVMTLFVP
>Mature_353_residues
PFIWLAYFFPLAALALGLAVSVLPVPFTGGLSFIETVLLIGTSFAAVHHAEGISSRIGQPFGTLILTLSVTVIEVSVLVA
MMLNGENNPGVGREAVLSTVMFVCTGVVGACLLVGALRHREQEVRQQGVNGYLSVIIAISVLCLLLPQNTHAGLMGAVDP
FQISFIMCGTVVLYGAFLFMQTVRHRADFMPEASEPAPARPRRLVVHIPLLLAALGGIVLVSSGVAAGVEELLDRLHLRD
PDAVISAAVVAMLLLPETITAIRAARANDLQRSINTALGSALATIGLTMPAMVAISVWVDRPIYLGIEPEDRVQLLLVLV
LSIVSFGTGRTNLLNGFVHLVLFAIYVMTLFVP

Specific function: Possible cation transporter [H]

COG id: COG0387

COG function: function code P; Ca2+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1787468, Length=352, Percent_Identity=31.8181818181818, Blast_Score=164, Evalue=9e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004713
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 37663; Mature: 37532

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFIWLAYFFPLAALALGLAVSVLPVPFTGGLSFIETVLLIGTSFAAVHHAEGISSRIGQ
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PFGTLILTLSVTVIEVSVLVAMMLNGENNPGVGREAVLSTVMFVCTGVVGACLLVGALRH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
REQEVRQQGVNGYLSVIIAISVLCLLLPQNTHAGLMGAVDPFQISFIMCGTVVLYGAFLF
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
MQTVRHRADFMPEASEPAPARPRRLVVHIPLLLAALGGIVLVSSGVAAGVEELLDRLHLR
HHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
DPDAVISAAVVAMLLLPETITAIRAARANDLQRSINTALGSALATIGLTMPAMVAISVWV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRPIYLGIEPEDRVQLLLVLVLSIVSFGTGRTNLLNGFVHLVLFAIYVMTLFVP
CCCEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PFIWLAYFFPLAALALGLAVSVLPVPFTGGLSFIETVLLIGTSFAAVHHAEGISSRIGQ
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PFGTLILTLSVTVIEVSVLVAMMLNGENNPGVGREAVLSTVMFVCTGVVGACLLVGALRH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
REQEVRQQGVNGYLSVIIAISVLCLLLPQNTHAGLMGAVDPFQISFIMCGTVVLYGAFLF
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
MQTVRHRADFMPEASEPAPARPRRLVVHIPLLLAALGGIVLVSSGVAAGVEELLDRLHLR
HHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
DPDAVISAAVVAMLLLPETITAIRAARANDLQRSINTALGSALATIGLTMPAMVAISVWV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRPIYLGIEPEDRVQLLLVLVLSIVSFGTGRTNLLNGFVHLVLFAIYVMTLFVP
CCCEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Cytoplasm]; Proton [Periplasm]; Ca (II) [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: Na (I) [Cytoplasm] + Proton [Periplasm] = Proton [Cytoplasm] + Na (I) [Periplasm] Ca (II) [Cytoplasm] + Proton [Periplasm] = Ca (II) [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]