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The map label for this gene is pdxH [H]

Identifier: 158422821

GI number: 158422821

Start: 1339734

End: 1340384

Strand: Reverse

Name: pdxH [H]

Synonym: AZC_1197

Alternate gene names: 158422821

Gene position: 1340384-1339734 (Counterclockwise)

Preceding gene: 158422824

Following gene: 158422820

Centisome position: 24.96

GC content: 65.44

Gene sequence:

>651_bases
TTGGCTCCTGTCATGTCCGATTCCGCCATGGAACCCCAGAACCCCTTAACGTCTGGTGATTTCACCGCCGCCGATGAACC
GTTCCGGCTGTTTTCCGAATGGCTGAAGGATGCGGAACGCTCGGAACCCAATGACCCCAATGCCATGACGCTCGCCACCG
TCGACCCCGACGGACTGCCGGATGCCCGCATGGTGCTGCTGAAGGGGCTCGATGACCGGGGCTTCGTTTTCTATACCAAC
ACCGAGAGCGCCAAGGGCCGGGAGCTGACCGCTCACCCCAAGGCGGCGCTAGTGTTCCATTGGAAGAGCCTGCGCCGTCA
GGTGCGTGTGCGCGGCCCGGTGGAGCGGGTGACCGACGCCGAAGCGGATGCCTATTTCGCCACCCGCCCCCGCCTGTCGC
AGATCGGTGCCTGGGCGAGCCAGCAGTCCCGCCCGCTGGAAGGGCGCTTCGCCCTCGAGGCGGCGGTCGCCACCACGACT
GCCCGCTACGCCGTCGGCAGCGTGCCGCGCCCGCCCCACTGGACCGGTTTCCGCATCCTGCCGGTGCAGATTGAATTCTG
GCACGATCGCCCGTTCCGGCTGCACGACCGCGTCGTCTTCAAGCGGGAAAATCCGGAAATCGACTGGGAAAAGAGCCGTC
TTTATCCCTGA

Upstream 100 bases:

>100_bases
TCGGACCGCGCGAAGCACTGGCCGCGCGGCGACATCGCGCCTATATGGGCGCCGTATCTCCGGCCCGCGCCGTACGAAAT
ACCGATGCGGCGACACGCGA

Downstream 100 bases:

>100_bases
TCCTTGACCGTCGGGCGCTGCCCGTGCTGCCTGCGGTTCAAACAAGACGTTGCACCGCAGCATCCTCCCTTCCGAAAGTC
CGCACCATGGTCGCCGTTTC

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MAPVMSDSAMEPQNPLTSGDFTAADEPFRLFSEWLKDAERSEPNDPNAMTLATVDPDGLPDARMVLLKGLDDRGFVFYTN
TESAKGRELTAHPKAALVFHWKSLRRQVRVRGPVERVTDAEADAYFATRPRLSQIGAWASQQSRPLEGRFALEAAVATTT
ARYAVGSVPRPPHWTGFRILPVQIEFWHDRPFRLHDRVVFKRENPEIDWEKSRLYP

Sequences:

>Translated_216_residues
MAPVMSDSAMEPQNPLTSGDFTAADEPFRLFSEWLKDAERSEPNDPNAMTLATVDPDGLPDARMVLLKGLDDRGFVFYTN
TESAKGRELTAHPKAALVFHWKSLRRQVRVRGPVERVTDAEADAYFATRPRLSQIGAWASQQSRPLEGRFALEAAVATTT
ARYAVGSVPRPPHWTGFRILPVQIEFWHDRPFRLHDRVVFKRENPEIDWEKSRLYP
>Mature_215_residues
APVMSDSAMEPQNPLTSGDFTAADEPFRLFSEWLKDAERSEPNDPNAMTLATVDPDGLPDARMVLLKGLDDRGFVFYTNT
ESAKGRELTAHPKAALVFHWKSLRRQVRVRGPVERVTDAEADAYFATRPRLSQIGAWASQQSRPLEGRFALEAAVATTTA
RYAVGSVPRPPHWTGFRILPVQIEFWHDRPFRLHDRVVFKRENPEIDWEKSRLYP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=205, Percent_Identity=42.4390243902439, Blast_Score=159, Evalue=2e-39,
Organism=Escherichia coli, GI1787926, Length=191, Percent_Identity=44.5026178010471, Blast_Score=167, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI17553712, Length=197, Percent_Identity=40.1015228426396, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6319509, Length=229, Percent_Identity=38.8646288209607, Blast_Score=158, Evalue=5e-40,
Organism=Drosophila melanogaster, GI45551845, Length=185, Percent_Identity=40, Blast_Score=128, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24644901, Length=185, Percent_Identity=40, Blast_Score=128, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24644903, Length=191, Percent_Identity=27.2251308900524, Blast_Score=77, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 24576; Mature: 24445

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPVMSDSAMEPQNPLTSGDFTAADEPFRLFSEWLKDAERSEPNDPNAMTLATVDPDGLP
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCC
DARMVLLKGLDDRGFVFYTNTESAKGRELTAHPKAALVFHWKSLRRQVRVRGPVERVTDA
HHHHHEEECCCCCCEEEEECCCCCCCCEEECCCCEEEEEEHHHHHHHHHCCCCHHHHCCC
EADAYFATRPRLSQIGAWASQQSRPLEGRFALEAAVATTTARYAVGSVPRPPHWTGFRIL
CCCEEEECCCCHHHHHCHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
PVQIEFWHDRPFRLHDRVVFKRENPEIDWEKSRLYP
EEEEEEECCCCCEECCEEEEECCCCCCCCHHCCCCC
>Mature Secondary Structure 
APVMSDSAMEPQNPLTSGDFTAADEPFRLFSEWLKDAERSEPNDPNAMTLATVDPDGLP
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCC
DARMVLLKGLDDRGFVFYTNTESAKGRELTAHPKAALVFHWKSLRRQVRVRGPVERVTDA
HHHHHEEECCCCCCEEEEECCCCCCCCEEECCCCEEEEEEHHHHHHHHHCCCCHHHHCCC
EADAYFATRPRLSQIGAWASQQSRPLEGRFALEAAVATTTARYAVGSVPRPPHWTGFRIL
CCCEEEECCCCHHHHHCHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
PVQIEFWHDRPFRLHDRVVFKRENPEIDWEKSRLYP
EEEEEEECCCCCEECCEEEEECCCCCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA