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The map label for this gene is betA [H]

Identifier: 158422807

GI number: 158422807

Start: 1322586

End: 1324274

Strand: Reverse

Name: betA [H]

Synonym: AZC_1183

Alternate gene names: 158422807

Gene position: 1324274-1322586 (Counterclockwise)

Preceding gene: 158422808

Following gene: 158422804

Centisome position: 24.66

GC content: 66.19

Gene sequence:

>1689_bases
TTGATGGAGCGAACCGTGGCCTCCCCCGCGTCCCCCGCCATCTTCGATTATGTCATCGTGGGCTCCGGCTCGGCCGGCGC
CGTGCTTGCCGACCGGCTCTCCGCTGACGGACGCTTCACGGTGCACGTGCTGGAATATGGCGGCTCGGACCGCTCCCTGC
TCATCCAGATGCCGGCAGCCCTCTCCATCCCCATGAACATGCCGAAATACAACTGGGGCTTCGAGACGGAGCCGGAGCCG
GGGCTCGGCGGCCGGCGTCTGGTCTGCCCGCGCGGCAAGGTGATCGGGGGATCATCCTCGGTCAACGGCATGGTCTATGT
GCGTGGCAATCCGCATGATTTCGACCGCTGGGAGGAAGAAGGCGCGCAGGGCTGGGGCTATCGCCACGTGCTGCCCTATT
TCCAGCGCGCGGAAAGCCGGCAGGAGGGGGGCGATGCCTATCGCGGCGCCACAGGCCCGCTAGCCACCCGCTACGGCCCG
TTGGAAAATCCGCTTTACAACGTGTTCGTGGAGGCCGCGCGTCAGGCCGGCTATCCTGCCACCTCGGACATCAATGGCGC
CCAGCAGGAAGGCTTCGGGCGCATGGACATGACGGTGAAGGACGGCGTGCGCTGGTCCACCGCCAATGCCTATCTCAAGC
CCGCCTTGAAGCGCCCCAACCTGTCGCTTGAAACCCACGCTTTGGTGCTGGCGGTCGAGTTAGAAGGCCGCCGGGCCGTG
GGCGTGCGCTATGAGCGGGACGGCACGGAGCAGATCGTGAAGGCAAGCCGGGAGGTGATCCTCGCTGCCGGGCCGATCAA
CTCGCCCAAGCTCCTCAAGCTCTCGGGCATCGGCCCGGCGCAGGAACTGGCCGACCTCGGAATCCCCGTCGTGGCGGATC
GGCCGGGGGTGGGTGAGAACTTGCAGGACCATCTGGAGTTCTATTTCCAGGTGGCCTGCACGCAGCCGATCACCCTTTAT
TCCAAGACCGGCCTCCTCTCGCGCGGGCTCGTGGGTGCGCAATGGCTTTTGGCCCGCTCCGGGCTTGGCGCCAGCAACCA
TTTCGAGAGCTGCGGCTTCATCCGCTCGCGCGCGGGCATCCGTTATCCGGACATCCAGTATCATTTCCTGCCGCTGGCGG
TGAGCTATGACGGCAAGGGCCTCGCCAGCGAACACGGGTTTCAGGCCCATGTGGGCCCCATGCGCAGCAAGAGCCGGGGC
TGGGTGCGACTGCGCTCGCGCGATGCGCGCGAACATCCGCGCATCTTCTTCAATTATCTCGGCCATGAGGACGACATCAC
CGAGATGCGCGCCTGCGTGCGCCTCACCCGCGAGATTTTCGCCCAGGCCGCCTTCGATCCCTATCGCGGGCGCGAGATCC
AGCCCGGCGCCGACGTCACCTCGGACGAGGCGATCGACGCCTTCGTGCGCGAGAAGGTGGAGAGCGCCTATCACCCCTCG
TGCAGTTGCCGGATGGGGCGGGCGGACGATCCCATGGCGGTGGTGACGCCCGATACCAAGGTGATCGGCATCGAAGGCCT
GCGGGTGGTGGATAGTTCCATCATGCCGTCGGTCACGACGGGCAATCTCAACGCCCCCACCATCATGATCGGCGAGAAGG
CCTCGGACATCATCCTCGGCAAGCCGGCCCTCGCCGCCTCTAACGCGCCCTATTACACCGCGGAGAACTGGCGCACCGCC
CAGCGCTGA

Upstream 100 bases:

>100_bases
AGCAGTCCGGTCTCGGGCGCGAGAACAGCCGCGCCGCCATCGAGCACTACACGCAGATCAAGAGCGTCTACGTCAATCTC
GGCCGCGTGGCCTCTCCTTA

Downstream 100 bases:

>100_bases
ACGGCGCGCCGGGGCTCAGACCGCGCCCACCGCCCACGCAACGCCCAGCATGGCGAGCGCTACACCCCAGGTGTAAAGCA
GCGAATGGCGGATGTGGGCG

Product: choline dehydrogenase

Products: NA

Alternate protein names: CDH; CHD [H]

Number of amino acids: Translated: 562; Mature: 562

Protein sequence:

>562_residues
MMERTVASPASPAIFDYVIVGSGSAGAVLADRLSADGRFTVHVLEYGGSDRSLLIQMPAALSIPMNMPKYNWGFETEPEP
GLGGRRLVCPRGKVIGGSSSVNGMVYVRGNPHDFDRWEEEGAQGWGYRHVLPYFQRAESRQEGGDAYRGATGPLATRYGP
LENPLYNVFVEAARQAGYPATSDINGAQQEGFGRMDMTVKDGVRWSTANAYLKPALKRPNLSLETHALVLAVELEGRRAV
GVRYERDGTEQIVKASREVILAAGPINSPKLLKLSGIGPAQELADLGIPVVADRPGVGENLQDHLEFYFQVACTQPITLY
SKTGLLSRGLVGAQWLLARSGLGASNHFESCGFIRSRAGIRYPDIQYHFLPLAVSYDGKGLASEHGFQAHVGPMRSKSRG
WVRLRSRDAREHPRIFFNYLGHEDDITEMRACVRLTREIFAQAAFDPYRGREIQPGADVTSDEAIDAFVREKVESAYHPS
CSCRMGRADDPMAVVTPDTKVIGIEGLRVVDSSIMPSVTTGNLNAPTIMIGEKASDIILGKPALAASNAPYYTAENWRTA
QR

Sequences:

>Translated_562_residues
MMERTVASPASPAIFDYVIVGSGSAGAVLADRLSADGRFTVHVLEYGGSDRSLLIQMPAALSIPMNMPKYNWGFETEPEP
GLGGRRLVCPRGKVIGGSSSVNGMVYVRGNPHDFDRWEEEGAQGWGYRHVLPYFQRAESRQEGGDAYRGATGPLATRYGP
LENPLYNVFVEAARQAGYPATSDINGAQQEGFGRMDMTVKDGVRWSTANAYLKPALKRPNLSLETHALVLAVELEGRRAV
GVRYERDGTEQIVKASREVILAAGPINSPKLLKLSGIGPAQELADLGIPVVADRPGVGENLQDHLEFYFQVACTQPITLY
SKTGLLSRGLVGAQWLLARSGLGASNHFESCGFIRSRAGIRYPDIQYHFLPLAVSYDGKGLASEHGFQAHVGPMRSKSRG
WVRLRSRDAREHPRIFFNYLGHEDDITEMRACVRLTREIFAQAAFDPYRGREIQPGADVTSDEAIDAFVREKVESAYHPS
CSCRMGRADDPMAVVTPDTKVIGIEGLRVVDSSIMPSVTTGNLNAPTIMIGEKASDIILGKPALAASNAPYYTAENWRTA
QR
>Mature_562_residues
MMERTVASPASPAIFDYVIVGSGSAGAVLADRLSADGRFTVHVLEYGGSDRSLLIQMPAALSIPMNMPKYNWGFETEPEP
GLGGRRLVCPRGKVIGGSSSVNGMVYVRGNPHDFDRWEEEGAQGWGYRHVLPYFQRAESRQEGGDAYRGATGPLATRYGP
LENPLYNVFVEAARQAGYPATSDINGAQQEGFGRMDMTVKDGVRWSTANAYLKPALKRPNLSLETHALVLAVELEGRRAV
GVRYERDGTEQIVKASREVILAAGPINSPKLLKLSGIGPAQELADLGIPVVADRPGVGENLQDHLEFYFQVACTQPITLY
SKTGLLSRGLVGAQWLLARSGLGASNHFESCGFIRSRAGIRYPDIQYHFLPLAVSYDGKGLASEHGFQAHVGPMRSKSRG
WVRLRSRDAREHPRIFFNYLGHEDDITEMRACVRLTREIFAQAAFDPYRGREIQPGADVTSDEAIDAFVREKVESAYHPS
CSCRMGRADDPMAVVTPDTKVIGIEGLRVVDSSIMPSVTTGNLNAPTIMIGEKASDIILGKPALAASNAPYYTAENWRTA
QR

Specific function: Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=545, Percent_Identity=55.4128440366973, Blast_Score=605, Evalue=1e-173,
Organism=Escherichia coli, GI1786503, Length=547, Percent_Identity=52.2851919561243, Blast_Score=566, Evalue=1e-162,
Organism=Caenorhabditis elegans, GI17532301, Length=564, Percent_Identity=46.0992907801418, Blast_Score=515, Evalue=1e-146,
Organism=Drosophila melanogaster, GI24642048, Length=564, Percent_Identity=35.9929078014184, Blast_Score=332, Evalue=4e-91,
Organism=Drosophila melanogaster, GI45551458, Length=563, Percent_Identity=36.234458259325, Blast_Score=331, Evalue=9e-91,
Organism=Drosophila melanogaster, GI45549471, Length=563, Percent_Identity=36.234458259325, Blast_Score=330, Evalue=1e-90,
Organism=Drosophila melanogaster, GI24642042, Length=563, Percent_Identity=35.1687388987567, Blast_Score=306, Evalue=2e-83,
Organism=Drosophila melanogaster, GI24642055, Length=569, Percent_Identity=34.622144112478, Blast_Score=298, Evalue=6e-81,
Organism=Drosophila melanogaster, GI24642059, Length=567, Percent_Identity=34.0388007054674, Blast_Score=297, Evalue=1e-80,
Organism=Drosophila melanogaster, GI17137792, Length=558, Percent_Identity=33.6917562724014, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24642051, Length=563, Percent_Identity=32.6820603907638, Blast_Score=272, Evalue=6e-73,
Organism=Drosophila melanogaster, GI18859995, Length=562, Percent_Identity=33.0960854092527, Blast_Score=265, Evalue=9e-71,
Organism=Drosophila melanogaster, GI24650267, Length=563, Percent_Identity=33.0373001776199, Blast_Score=264, Evalue=1e-70,
Organism=Drosophila melanogaster, GI24642039, Length=565, Percent_Identity=32.5663716814159, Blast_Score=257, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24642037, Length=571, Percent_Identity=33.2749562171629, Blast_Score=251, Evalue=9e-67,
Organism=Drosophila melanogaster, GI24642035, Length=572, Percent_Identity=31.2937062937063, Blast_Score=248, Evalue=6e-66,
Organism=Drosophila melanogaster, GI18859993, Length=568, Percent_Identity=33.0985915492958, Blast_Score=244, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24645930, Length=581, Percent_Identity=27.3666092943201, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI24642057, Length=584, Percent_Identity=28.5958904109589, Blast_Score=137, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011533
- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.1 [H]

Molecular weight: Translated: 61378; Mature: 61378

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS00623 GMC_OXRED_1 ; PS00624 GMC_OXRED_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMERTVASPASPAIFDYVIVGSGSAGAVLADRLSADGRFTVHVLEYGGSDRSLLIQMPAA
CCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHCCCCEEEEEEEEECCCCCEEEEECCCE
LSIPMNMPKYNWGFETEPEPGLGGRRLVCPRGKVIGGSSSVNGMVYVRGNPHDFDRWEEE
EECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEECCCCCCCEEEEECCCCCCCHHHHHH
GAQGWGYRHVLPYFQRAESRQEGGDAYRGATGPLATRYGPLENPLYNVFVEAARQAGYPA
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCC
TSDINGAQQEGFGRMDMTVKDGVRWSTANAYLKPALKRPNLSLETHALVLAVELEGRRAV
CCCCCCHHHCCCCCCCEEHHCCCEEECCCHHHHHHHCCCCCCEEEEEEEEEEEECCCEEE
GVRYERDGTEQIVKASREVILAAGPINSPKLLKLSGIGPAQELADLGIPVVADRPGVGEN
EEEECCCCHHHHHHCCCCEEEEECCCCCCCEEEEECCCCHHHHHHCCCEEEECCCCCCCC
LQDHLEFYFQVACTQPITLYSKTGLLSRGLVGAQWLLARSGLGASNHFESCGFIRSRAGI
HHHHHHHHHHHCCCCCEEEEECCCCHHCCCHHHHHHHHHCCCCCCCCCHHCCHHHHCCCC
RYPDIQYHFLPLAVSYDGKGLASEHGFQAHVGPMRSKSRGWVRLRSRDAREHPRIFFNYL
CCCCCEEEEEEEEEEECCCCCCCCCCCEECCCCCCCCCCCEEEEECCCCCCCCEEEEECC
GHEDDITEMRACVRLTREIFAQAAFDPYRGREIQPGADVTSDEAIDAFVREKVESAYHPS
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
CSCRMGRADDPMAVVTPDTKVIGIEGLRVVDSSIMPSVTTGNLNAPTIMIGEKASDIILG
CCEECCCCCCCEEEECCCCEEEECCCEEEECCCCCCCEECCCCCCCEEEECCCCCCEEEC
KPALAASNAPYYTAENWRTAQR
CCCCCCCCCCEEECCCCCCCCC
>Mature Secondary Structure
MMERTVASPASPAIFDYVIVGSGSAGAVLADRLSADGRFTVHVLEYGGSDRSLLIQMPAA
CCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHCCCCEEEEEEEEECCCCCEEEEECCCE
LSIPMNMPKYNWGFETEPEPGLGGRRLVCPRGKVIGGSSSVNGMVYVRGNPHDFDRWEEE
EECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEECCCCCCCEEEEECCCCCCCHHHHHH
GAQGWGYRHVLPYFQRAESRQEGGDAYRGATGPLATRYGPLENPLYNVFVEAARQAGYPA
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCC
TSDINGAQQEGFGRMDMTVKDGVRWSTANAYLKPALKRPNLSLETHALVLAVELEGRRAV
CCCCCCHHHCCCCCCCEEHHCCCEEECCCHHHHHHHCCCCCCEEEEEEEEEEEECCCEEE
GVRYERDGTEQIVKASREVILAAGPINSPKLLKLSGIGPAQELADLGIPVVADRPGVGEN
EEEECCCCHHHHHHCCCCEEEEECCCCCCCEEEEECCCCHHHHHHCCCEEEECCCCCCCC
LQDHLEFYFQVACTQPITLYSKTGLLSRGLVGAQWLLARSGLGASNHFESCGFIRSRAGI
HHHHHHHHHHHCCCCCEEEEECCCCHHCCCHHHHHHHHHCCCCCCCCCHHCCHHHHCCCC
RYPDIQYHFLPLAVSYDGKGLASEHGFQAHVGPMRSKSRGWVRLRSRDAREHPRIFFNYL
CCCCCEEEEEEEEEEECCCCCCCCCCCEECCCCCCCCCCCEEEEECCCCCCCCEEEEECC
GHEDDITEMRACVRLTREIFAQAAFDPYRGREIQPGADVTSDEAIDAFVREKVESAYHPS
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
CSCRMGRADDPMAVVTPDTKVIGIEGLRVVDSSIMPSVTTGNLNAPTIMIGEKASDIILG
CCEECCCCCCCEEEECCCCEEEECCCEEEECCCCCCCEECCCCCCCEEEECCCCCCEEEC
KPALAASNAPYYTAENWRTAQR
CCCCCCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA