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The map label for this gene is lysR [H]

Identifier: 158422804

GI number: 158422804

Start: 1318927

End: 1319850

Strand: Reverse

Name: lysR [H]

Synonym: AZC_1180

Alternate gene names: 158422804

Gene position: 1319850-1318927 (Counterclockwise)

Preceding gene: 158422807

Following gene: 158422796

Centisome position: 24.58

GC content: 68.61

Gene sequence:

>924_bases
ATGCGCATCAATTACGATTTGCCCGAACTGCGGGCCTTCCTCACCGTCGCCCGCCTGCGCAATTTCGGCCGGACGGCGGC
GGCGCTGAACCTGTCGCCCTCGGCGATCAGCCGCCGCATCTCGGAACTTGAGCAGGCTCTCAACGTGCAGCTTCTGGAGC
GCACCACCCGTTCCGTGGTGCTCACCGCCGCCGGCCGGGCGCTGGTGGCCGAAGTGGCGCCTCTGCTGGAGAAGATGGAT
CAGGGCCTCAATGCCATCGTGGACGAAGCCCGCGGCAAGGGCGGCTGGCTGGATGTCGGCTGCGTCACCACGGTCGCCTT
CAGCATCGCGCCCGGCGTTGCCGACCGCTTCCGCCGCGCCTATCCAGACATGCACCTGCGCTTTCACGACGACACCGGCA
AGCGTGTCACCGAAAGCGTCATGGTCGGTGGTGTCGCCTTCGCGGTGAACACCCTGCTCCAGCCGCCGAGCGAACTGCTG
GCGGAGCATCTGCTGGACGATCCTTATGTGCTCGTTCTGCCGCGCGATCACCCCTGCGCAAGTCTGGACGCATTCCCGTG
GGCGGACCTGTCCGACCTGCCGCGCGGCGGCGTGCCGCTGGTGGCGCTCAAGCAGTCGAGCGCCAACCGCAAGGAGATGG
ATGCGGCCTTGGAACAGGCGGGCGTCGATGCCCCCTGGAGCGACGAGGTGGAACACCTCTCCACCATGCTCGGCTTCCTG
CGGGCAGGGGGCGTTGCGGCGGTGATGCCCCGCCTCGCCCTGCTCGCCTGCGCGGACTGGGGCCTCTCCCATGTGCGGCT
GTGCGATCCGGCGATCCACCGCCGCATCGGCCTCATCCGCCGCAAGGATCTGGTGCTCTCGGAGCCCGCACGGCGGCTAT
GGGATCTGTTCGCCGAGGAACTGCGGACGCACGCCGCGCCCTGA

Upstream 100 bases:

>100_bases
GATGACGGGCATAGGCACTCCCAGAGAACGTGTTCTTTTCCGTACTATGCCGGGCCGCCATATTGATAATAAGTGATAAT
TCGGCAATGATTATGCAGTA

Downstream 100 bases:

>100_bases
TTGGTCTCAGTCGTCTGCGGACCGTGCGCCCGCAAGACCAAGCCCGCGGAGATAGCTCAGGATTTCCCGCGCTGCCTCCT
CCGGCGCAGGATCGACGAGC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MRINYDLPELRAFLTVARLRNFGRTAAALNLSPSAISRRISELEQALNVQLLERTTRSVVLTAAGRALVAEVAPLLEKMD
QGLNAIVDEARGKGGWLDVGCVTTVAFSIAPGVADRFRRAYPDMHLRFHDDTGKRVTESVMVGGVAFAVNTLLQPPSELL
AEHLLDDPYVLVLPRDHPCASLDAFPWADLSDLPRGGVPLVALKQSSANRKEMDAALEQAGVDAPWSDEVEHLSTMLGFL
RAGGVAAVMPRLALLACADWGLSHVRLCDPAIHRRIGLIRRKDLVLSEPARRLWDLFAEELRTHAAP

Sequences:

>Translated_307_residues
MRINYDLPELRAFLTVARLRNFGRTAAALNLSPSAISRRISELEQALNVQLLERTTRSVVLTAAGRALVAEVAPLLEKMD
QGLNAIVDEARGKGGWLDVGCVTTVAFSIAPGVADRFRRAYPDMHLRFHDDTGKRVTESVMVGGVAFAVNTLLQPPSELL
AEHLLDDPYVLVLPRDHPCASLDAFPWADLSDLPRGGVPLVALKQSSANRKEMDAALEQAGVDAPWSDEVEHLSTMLGFL
RAGGVAAVMPRLALLACADWGLSHVRLCDPAIHRRIGLIRRKDLVLSEPARRLWDLFAEELRTHAAP
>Mature_307_residues
MRINYDLPELRAFLTVARLRNFGRTAAALNLSPSAISRRISELEQALNVQLLERTTRSVVLTAAGRALVAEVAPLLEKMD
QGLNAIVDEARGKGGWLDVGCVTTVAFSIAPGVADRFRRAYPDMHLRFHDDTGKRVTESVMVGGVAFAVNTLLQPPSELL
AEHLLDDPYVLVLPRDHPCASLDAFPWADLSDLPRGGVPLVALKQSSANRKEMDAALEQAGVDAPWSDEVEHLSTMLGFL
RAGGVAAVMPRLALLACADWGLSHVRLCDPAIHRRIGLIRRKDLVLSEPARRLWDLFAEELRTHAAP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=299, Percent_Identity=33.4448160535117, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1788748, Length=298, Percent_Identity=32.8859060402685, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI157672245, Length=286, Percent_Identity=30.0699300699301, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787879, Length=197, Percent_Identity=33.502538071066, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1790399, Length=298, Percent_Identity=24.8322147651007, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI2367136, Length=190, Percent_Identity=32.6315789473684, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787601, Length=180, Percent_Identity=27.2222222222222, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790208, Length=174, Percent_Identity=31.0344827586207, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788887, Length=180, Percent_Identity=32.2222222222222, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788297, Length=245, Percent_Identity=25.3061224489796, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787589, Length=145, Percent_Identity=31.0344827586207, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87081978, Length=137, Percent_Identity=32.8467153284672, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787128, Length=131, Percent_Identity=33.587786259542, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787530, Length=306, Percent_Identity=24.1830065359477, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33597; Mature: 33597

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRINYDLPELRAFLTVARLRNFGRTAAALNLSPSAISRRISELEQALNVQLLERTTRSVV
CCCCCCHHHHHHHHHHHHHHHCCCHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHEE
LTAAGRALVAEVAPLLEKMDQGLNAIVDEARGKGGWLDVGCVTTVAFSIAPGVADRFRRA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCHHHHHHHH
YPDMHLRFHDDTGKRVTESVMVGGVAFAVNTLLQPPSELLAEHLLDDPYVLVLPRDHPCA
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCCCC
SLDAFPWADLSDLPRGGVPLVALKQSSANRKEMDAALEQAGVDAPWSDEVEHLSTMLGFL
CCCCCCCCCHHHCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
RAGGVAAVMPRLALLACADWGLSHVRLCDPAIHRRIGLIRRKDLVLSEPARRLWDLFAEE
HHCCHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRTHAAP
HHHCCCC
>Mature Secondary Structure
MRINYDLPELRAFLTVARLRNFGRTAAALNLSPSAISRRISELEQALNVQLLERTTRSVV
CCCCCCHHHHHHHHHHHHHHHCCCHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHEE
LTAAGRALVAEVAPLLEKMDQGLNAIVDEARGKGGWLDVGCVTTVAFSIAPGVADRFRRA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCHHHHHHHH
YPDMHLRFHDDTGKRVTESVMVGGVAFAVNTLLQPPSELLAEHLLDDPYVLVLPRDHPCA
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCCCC
SLDAFPWADLSDLPRGGVPLVALKQSSANRKEMDAALEQAGVDAPWSDEVEHLSTMLGFL
CCCCCCCCCHHHCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
RAGGVAAVMPRLALLACADWGLSHVRLCDPAIHRRIGLIRRKDLVLSEPARRLWDLFAEE
HHCCHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRTHAAP
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]