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The map label for this gene is selA [H]

Identifier: 158422779

GI number: 158422779

Start: 1287892

End: 1289307

Strand: Reverse

Name: selA [H]

Synonym: AZC_1155

Alternate gene names: 158422779

Gene position: 1289307-1287892 (Counterclockwise)

Preceding gene: 158422780

Following gene: 158422778

Centisome position: 24.01

GC content: 72.25

Gene sequence:

>1416_bases
ATGAGCAGCGGTTCGAGCGTGGCGGACGTCTCCGCCTTGCGGCGCCTGCCGTCCGTCGATCAGGTGCTGAAAGCCGGCCC
CGCCCTTGCGGCAGTGGAGCGCTTCGGCCGCGCCGAGGCGACGGAAGCCGTGCGCACCGCCCTTGACGCCGCCCGCGCCG
CCTTGCGCGCGGGCACTCCGGCACCAGTGGATGCGGAGGGCATCGCCGCTGCCGCCCTCGCGGCGCTGGCGGCGGATGCG
CGCGCCTCCCTCTGTCCGGTGTTCAATCTCACCGGCACGGTACTGCACACCAATCTCGGCCGGGCGCTGCTGGCGGAAGA
GGCGGTGGAGGCGGCGGTGGCTGCCATGCGCTCGGCCGTGGCCCTGGAATATGACCTCGACAGCGGCAAGCGCGGCGAGC
GCGACGACCATGTGCGCGACCTGCTCTGCCGCCTCACGGGCGCGGAGGACGCCACCGTCGTCAACAACAACGCCGCCGCC
GTGCTGCTGGTGCTGAACACGCTGGCGGCGGGGCGCGACAGCATCGTCTCGCGCGGCGAGTTGATCGAGATCGGCGGCGC
CTTCCGCATGCCGGACATCATGGCCCGCGCCGGCACGCGCCTTGTGGAAGTGGGCACCACCAACCGCACCCACCCGAAGG
ACTATCGCGGCGCGCTCTCGCCCGAAACCGGGCTGATCGTGAAGGTGCACACCTCCAATTACCGCATCGAGGGCTTCACC
GCCGAAGTGCCGCCGAAGGAGCTGGCCGCCATCGGCCATGAGGCGCATGTGCCGCTGTTCAACGACCTCGGCTCCGGCAC
GCTGGCGGACCTTGCCGCCTATGGCCTCGTCCACGAGCCCACCGTCCGCGAGGCGGTGGCGGAAGGCGCGGACATCGTGA
CCTTCTCCGGCGACAAGCTGCTGGGCGGGCCGCAGACCGGCTTCATCGTCGGCCGGCGCGATCTCATCGCCGCCATCAAC
AAGAACCCCATGAAGCGGGCGCTGCGGGTGGACAAGATCCGCCTCGCGGCGCTGGAAGCAACGCTAAAGCTCTATCTCGA
CCCCGACCGCCTCGCCCGCCGCCTGCCGACCCTGCGCCTGCTCACCCGCCAGCCCGCCGAAATGGCGGCCGTGGCGGCCC
GCGTGCGCCCCGTGCTGGCGGCGAAGCTCGGGGAGGCCTTCACCATCGAGGAGCGGGCGTGCAAGAGCCAGATCGGCTCC
GGCGCGCTGCCGCTCGAAACGCTGGCGAGCACGGCGCTCGCCCTCATTCCCGCCGACGGCAGCGGTCGCCGGCTGGCCGC
GCTTGCCGACGCGCTGCGCGGCCTGCCCGTGCCCGTCGTCGGGCGCGTGGAAGACGGCGCGCTGCTGCTGGACCTGCGCT
GCCTGGAGGATGAGGCGGGCTTTGCCGCCAGCCTCGCGCATCTGGAGCCTGCCTGA

Upstream 100 bases:

>100_bases
GCGGACGACGTGGCGACGCTCGGGCTCGACATGCTGATGCGGGATCGGCCCTACAAGCGCGCCGCGTTCAATCCCTTCCT
GATCGGCTATTGAGGCGGCC

Downstream 100 bases:

>100_bases
TGGGCCTGTTCGATTTTCTCCGCCGCCCCGCCCCCTGCCCGCCCCCGAGCGAGAGCGTGGAGGCGCGCATGGGCCGCGCC
CTCGATGCCGCCGCGAGCGG

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MSSGSSVADVSALRRLPSVDQVLKAGPALAAVERFGRAEATEAVRTALDAARAALRAGTPAPVDAEGIAAAALAALAADA
RASLCPVFNLTGTVLHTNLGRALLAEEAVEAAVAAMRSAVALEYDLDSGKRGERDDHVRDLLCRLTGAEDATVVNNNAAA
VLLVLNTLAAGRDSIVSRGELIEIGGAFRMPDIMARAGTRLVEVGTTNRTHPKDYRGALSPETGLIVKVHTSNYRIEGFT
AEVPPKELAAIGHEAHVPLFNDLGSGTLADLAAYGLVHEPTVREAVAEGADIVTFSGDKLLGGPQTGFIVGRRDLIAAIN
KNPMKRALRVDKIRLAALEATLKLYLDPDRLARRLPTLRLLTRQPAEMAAVAARVRPVLAAKLGEAFTIEERACKSQIGS
GALPLETLASTALALIPADGSGRRLAALADALRGLPVPVVGRVEDGALLLDLRCLEDEAGFAASLAHLEPA

Sequences:

>Translated_471_residues
MSSGSSVADVSALRRLPSVDQVLKAGPALAAVERFGRAEATEAVRTALDAARAALRAGTPAPVDAEGIAAAALAALAADA
RASLCPVFNLTGTVLHTNLGRALLAEEAVEAAVAAMRSAVALEYDLDSGKRGERDDHVRDLLCRLTGAEDATVVNNNAAA
VLLVLNTLAAGRDSIVSRGELIEIGGAFRMPDIMARAGTRLVEVGTTNRTHPKDYRGALSPETGLIVKVHTSNYRIEGFT
AEVPPKELAAIGHEAHVPLFNDLGSGTLADLAAYGLVHEPTVREAVAEGADIVTFSGDKLLGGPQTGFIVGRRDLIAAIN
KNPMKRALRVDKIRLAALEATLKLYLDPDRLARRLPTLRLLTRQPAEMAAVAARVRPVLAAKLGEAFTIEERACKSQIGS
GALPLETLASTALALIPADGSGRRLAALADALRGLPVPVVGRVEDGALLLDLRCLEDEAGFAASLAHLEPA
>Mature_470_residues
SSGSSVADVSALRRLPSVDQVLKAGPALAAVERFGRAEATEAVRTALDAARAALRAGTPAPVDAEGIAAAALAALAADAR
ASLCPVFNLTGTVLHTNLGRALLAEEAVEAAVAAMRSAVALEYDLDSGKRGERDDHVRDLLCRLTGAEDATVVNNNAAAV
LLVLNTLAAGRDSIVSRGELIEIGGAFRMPDIMARAGTRLVEVGTTNRTHPKDYRGALSPETGLIVKVHTSNYRIEGFTA
EVPPKELAAIGHEAHVPLFNDLGSGTLADLAAYGLVHEPTVREAVAEGADIVTFSGDKLLGGPQTGFIVGRRDLIAAINK
NPMKRALRVDKIRLAALEATLKLYLDPDRLARRLPTLRLLTRQPAEMAAVAARVRPVLAAKLGEAFTIEERACKSQIGSG
ALPLETLASTALALIPADGSGRRLAALADALRGLPVPVVGRVEDGALLLDLRCLEDEAGFAASLAHLEPA

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=451, Percent_Identity=54.5454545454545, Blast_Score=453, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 49136; Mature: 49005

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSGSSVADVSALRRLPSVDQVLKAGPALAAVERFGRAEATEAVRTALDAARAALRAGTP
CCCCCCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
APVDAEGIAAAALAALAADARASLCPVFNLTGTVLHTNLGRALLAEEAVEAAVAAMRSAV
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHH
ALEYDLDSGKRGERDDHVRDLLCRLTGAEDATVVNNNAAAVLLVLNTLAAGRDSIVSRGE
EEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCEEHHHHHHHHCCCHHHHCCCC
LIEIGGAFRMPDIMARAGTRLVEVGTTNRTHPKDYRGALSPETGLIVKVHTSNYRIEGFT
EEEECCCCCCHHHHHHCCCEEEEECCCCCCCCHHHCCCCCCCCCEEEEEECCCEEEEEEE
AEVPPKELAAIGHEAHVPLFNDLGSGTLADLAAYGLVHEPTVREAVAEGADIVTFSGDKL
CCCCHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCEEEECCCEE
LGGPQTGFIVGRRDLIAAINKNPMKRALRVDKIRLAALEATLKLYLDPDRLARRLPTLRL
CCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHCCHHHH
LTRQPAEMAAVAARVRPVLAAKLGEAFTIEERACKSQIGSGALPLETLASTALALIPADG
HHCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCCCHHHHHCCCEEEEECCC
SGRRLAALADALRGLPVPVVGRVEDGALLLDLRCLEDEAGFAASLAHLEPA
CCCHHHHHHHHHHCCCCCEEEEECCCEEEEEEEECCCCCCHHHHHHHCCCC
>Mature Secondary Structure 
SSGSSVADVSALRRLPSVDQVLKAGPALAAVERFGRAEATEAVRTALDAARAALRAGTP
CCCCCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
APVDAEGIAAAALAALAADARASLCPVFNLTGTVLHTNLGRALLAEEAVEAAVAAMRSAV
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHH
ALEYDLDSGKRGERDDHVRDLLCRLTGAEDATVVNNNAAAVLLVLNTLAAGRDSIVSRGE
EEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCEEHHHHHHHHCCCHHHHCCCC
LIEIGGAFRMPDIMARAGTRLVEVGTTNRTHPKDYRGALSPETGLIVKVHTSNYRIEGFT
EEEECCCCCCHHHHHHCCCEEEEECCCCCCCCHHHCCCCCCCCCEEEEEECCCEEEEEEE
AEVPPKELAAIGHEAHVPLFNDLGSGTLADLAAYGLVHEPTVREAVAEGADIVTFSGDKL
CCCCHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCEEEECCCEE
LGGPQTGFIVGRRDLIAAINKNPMKRALRVDKIRLAALEATLKLYLDPDRLARRLPTLRL
CCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHCCHHHH
LTRQPAEMAAVAARVRPVLAAKLGEAFTIEERACKSQIGSGALPLETLASTALALIPADG
HHCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCCCHHHHHCCCEEEEECCC
SGRRLAALADALRGLPVPVVGRVEDGALLLDLRCLEDEAGFAASLAHLEPA
CCCHHHHHHHHHHCCCCCEEEEECCCEEEEEEEECCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]