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The map label for this gene is ykoU [H]

Identifier: 158422630

GI number: 158422630

Start: 1126636

End: 1129338

Strand: Direct

Name: ykoU [H]

Synonym: AZC_1006

Alternate gene names: 158422630

Gene position: 1126636-1129338 (Clockwise)

Preceding gene: 158422629

Following gene: 158422631

Centisome position: 20.98

GC content: 68.81

Gene sequence:

>2703_bases
ATGGGCCTCAGCACCTATCGCGCCAAGCGCGACTTCACCGTGACTCCCGAGCCCGACGGCGGCGCGAAAGGCAAGGCCCG
CGCCGCAGCCAGCGCCTCGGCGGGCGCCTATGTGATCCAGAAGCACGCCGCCCGCCGCCTGCACTATGATCTGCGGCTGG
AGATGGATGGCGTGCTGAAGAGCTGGGCCGTCACGCGCGGGCCGAGCCTCGTGCCCGGTGAGAAGCGCCTCGCCGTGCAT
GTGGAGGACCATCCGCTCGCCTATGGCGGCTTCGAGGGTACCATCCCCGAGGGCCAGTACGGGGCGGGCAAGGTCATCGT
CTGGGATCGCGGCAGCTGGACCCCGGTGGGGGATCCGCACAAGGGCTACAAGAAGGGGCATCTGGAATTCGCACTCGACG
GCGAAAAGCTCCATGGCCGCTGGCATCTGGTGCGCATGTCACCCCACCCCGGCGACAAGAAGGAAAACTGGCTGCTCATC
AAGGTGGAGGACGAGGCGGCGCGCCCTGAGGGTGCGCCCGAGATTACCGACGAGGCGCCCCTCTCCGTCGTCTCGGGCCG
GGACGTTGAGGAAGTGGGTGCCCCATCGGCCGCAAAGTCCCCGAAGTTAAGCACGGCAAAGACGTCCAGGCCGAAGGCTG
CGGCACGCGATGCGAAGGCATCCGAGGAGGCCGAGACGACCGCAAGCGGCGCGGAGCGGGGTGCGCGCGCAGTGTCTGCT
CCGGCAAAAGCCAAGAAAACGACGGCCGCAAGGGTCAACGGACGCTCCACCCGCGCGACCGCCTGGGACCTGCCAAAGGG
CGCGAAACGCGCGCCTTTGCCGGATTTCCTGCCCCCGGCTCTCGCCACGCTGGCCAGGCAGGCGCCGAAGGGCCGGCGCT
ATGTCCATGAGATCAAGTTCGATGGCTATCGCATCGCCGCGCGGCTTGAGGATGGAGAGGTCCGCCTGCTTACGCGCACC
GGCCTCGACTGGTCCGCGCGCTTCGGGACGGCGATCCGGGAGGCGGCCGCGGCCCTTCCCGTATCCGATGCCATGCTTGA
TGGCGAGGTGGTGGTGGAGGGCGGCAACGGCGCCTCGGACTTCTCCGCCTTGCAGGCGGATCTGAGCGAAGGGCGCACGG
ACCGCTTCGTCTATTATGCCTTCGATCTCCTGCATCTCGACGGGCACGACCTGACGGGCGCGCCGCTCGCGGAGCGCAAG
GCGCTGCTGGAGCAATTGCTCACCAGAGCTGAAGGGAGCGGCGAAGGCGTCCTGCGCTACAGCGGCCATTTCGAGGATGA
CGGCGCCATGGTGCTCCAGCATGCCTGCCGGCTGAGCCTGGAGGGCGTCGTCTCCAAGCTCAAGGATGCGCCCTATCATT
CCGGCCGCTCGCGGGACTGGATCAAGTCCAAGTGCTCGGAGCGGCAGGAGTTCGTGATCGGCGGCTTCGTGCCCTCCACC
ACTGCCCGCAAGGCTATCGGCTCGCTGGTGCTCGGCGTCTATGAGGGCAAGCGCCTCGTCCATGTGGGGCGTGTGGGCAC
GGGCTTCTCGAACAAGATGGCGTCGGATCTCCACACCCTGCTGGCGCCCGAGGCGGTTGAGGAAAGTCCGTTTTCCGCGC
GGCTTACGGCGGATGAGGCGCGGGGCGTCACCTTTGTTGCGCCCAAGCGTGTGGCCGAAGTCGAGTTCCGCGCCTGGACG
GGAGACGGCCACCTGCGCCACGCCGCCTTCCGGGGACTGCGCGACGACAAGGCGGCCGCCGATGTGGTGCGCGAGGCCGC
GTCGCAGCCGGCCGAGACGCCCAAGACACCGCCCAAGCGCCGGGTGCGCCTCACCCATCCTGACCGCATCTACTGGCCGG
ATGCGGGCGTCACCAAGGAGGGATTGGCCGATTATTACGCAGAGGTCTGGCCGCGCATCGCGCCCTTTATCGTCGGCCGG
CCGCTGGCGCTGGTGCGTTGTCCGGAGGGCATCGAAGGGCAGCACTTCTTCCAGAAGCACCCGTGGAAGGGCGCGGACAA
GGCGCTGAAGGAGGTGCACGATCCCAAGGCCCCGGACGAGCCGCCCTATCTCGCCGTCGAGACGCTGGACGGGCTGATGG
CGCTGGTGCAGGGGGCGGCGCTGGAAATCCACCCCTTCGGTGCTCCGCTCTCGGACTGGGAGCGCCCGGACCTTCTCACC
ATGGATCTCGACCCCGGCGAGGGCGTCCCATGGAGCGCGGTCATCGCCGCTGCCCATGAGGTGAAGGCGCGCCTTGAGAC
GGCGGGCCTTGCCGCCTTCGTGAAGACCTCCGGCGGCAAGGGGCTGCATGTCTGCGCGCCGCTGAAGCCGCGGGCCGATT
GGACCGAACTCAAGGCCTTCACCAAGGCCATGGCCGAGACAATGGCGCAGGAGGCGCCCGACACCTATGTGGCGACCATC
ACCAAGGCCAAGCGGCGTGGCCGCATCCTTGTTGATTATCTGCGCAACCAGCGCGGCTCCACGGCGGTCGCGCCCTATTC
CGCCCGCGCGCGGGCCGGGGCGCCCGTCTCCATGCCCATCGCTTGGGAGGAGCTGGGCGAGGGCATGGGGCCCCAGCATT
TCACGGTTCTGAACGCACCGGCGCGGCTCGCCAATCTCTCGGCCGATCCATGGGCTGATTTCCGGAAGGCGGCGGCGCCC
CTGCCGGCGGGCAGAACGGCGGGCGGAACGGCCGGCGGCAAACGGCGCGGCGGGAGGCGCTGA

Upstream 100 bases:

>100_bases
CAAGACCCGCAAGGCAAAGAGTGCTGCGGCATCCGCCGGCGCGCAGACGCGGCGTACCGGCACCACCCGCAAGGCGGGGT
GAGACAAGGCGGAGCAGAAG

Downstream 100 bases:

>100_bases
TGGCACCCCGCGCCTTCTGGAAGGGCTGGCTGAAGCTCTCGCTCGTCACCTGCCGCGTCGCCATGTCCCCCGCCACCAGC
GACCGGGAGAAGGTGCGCTT

Product: ATP-dependent DNA ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 900; Mature: 899

Protein sequence:

>900_residues
MGLSTYRAKRDFTVTPEPDGGAKGKARAAASASAGAYVIQKHAARRLHYDLRLEMDGVLKSWAVTRGPSLVPGEKRLAVH
VEDHPLAYGGFEGTIPEGQYGAGKVIVWDRGSWTPVGDPHKGYKKGHLEFALDGEKLHGRWHLVRMSPHPGDKKENWLLI
KVEDEAARPEGAPEITDEAPLSVVSGRDVEEVGAPSAAKSPKLSTAKTSRPKAAARDAKASEEAETTASGAERGARAVSA
PAKAKKTTAARVNGRSTRATAWDLPKGAKRAPLPDFLPPALATLARQAPKGRRYVHEIKFDGYRIAARLEDGEVRLLTRT
GLDWSARFGTAIREAAAALPVSDAMLDGEVVVEGGNGASDFSALQADLSEGRTDRFVYYAFDLLHLDGHDLTGAPLAERK
ALLEQLLTRAEGSGEGVLRYSGHFEDDGAMVLQHACRLSLEGVVSKLKDAPYHSGRSRDWIKSKCSERQEFVIGGFVPST
TARKAIGSLVLGVYEGKRLVHVGRVGTGFSNKMASDLHTLLAPEAVEESPFSARLTADEARGVTFVAPKRVAEVEFRAWT
GDGHLRHAAFRGLRDDKAAADVVREAASQPAETPKTPPKRRVRLTHPDRIYWPDAGVTKEGLADYYAEVWPRIAPFIVGR
PLALVRCPEGIEGQHFFQKHPWKGADKALKEVHDPKAPDEPPYLAVETLDGLMALVQGAALEIHPFGAPLSDWERPDLLT
MDLDPGEGVPWSAVIAAAHEVKARLETAGLAAFVKTSGGKGLHVCAPLKPRADWTELKAFTKAMAETMAQEAPDTYVATI
TKAKRRGRILVDYLRNQRGSTAVAPYSARARAGAPVSMPIAWEELGEGMGPQHFTVLNAPARLANLSADPWADFRKAAAP
LPAGRTAGGTAGGKRRGGRR

Sequences:

>Translated_900_residues
MGLSTYRAKRDFTVTPEPDGGAKGKARAAASASAGAYVIQKHAARRLHYDLRLEMDGVLKSWAVTRGPSLVPGEKRLAVH
VEDHPLAYGGFEGTIPEGQYGAGKVIVWDRGSWTPVGDPHKGYKKGHLEFALDGEKLHGRWHLVRMSPHPGDKKENWLLI
KVEDEAARPEGAPEITDEAPLSVVSGRDVEEVGAPSAAKSPKLSTAKTSRPKAAARDAKASEEAETTASGAERGARAVSA
PAKAKKTTAARVNGRSTRATAWDLPKGAKRAPLPDFLPPALATLARQAPKGRRYVHEIKFDGYRIAARLEDGEVRLLTRT
GLDWSARFGTAIREAAAALPVSDAMLDGEVVVEGGNGASDFSALQADLSEGRTDRFVYYAFDLLHLDGHDLTGAPLAERK
ALLEQLLTRAEGSGEGVLRYSGHFEDDGAMVLQHACRLSLEGVVSKLKDAPYHSGRSRDWIKSKCSERQEFVIGGFVPST
TARKAIGSLVLGVYEGKRLVHVGRVGTGFSNKMASDLHTLLAPEAVEESPFSARLTADEARGVTFVAPKRVAEVEFRAWT
GDGHLRHAAFRGLRDDKAAADVVREAASQPAETPKTPPKRRVRLTHPDRIYWPDAGVTKEGLADYYAEVWPRIAPFIVGR
PLALVRCPEGIEGQHFFQKHPWKGADKALKEVHDPKAPDEPPYLAVETLDGLMALVQGAALEIHPFGAPLSDWERPDLLT
MDLDPGEGVPWSAVIAAAHEVKARLETAGLAAFVKTSGGKGLHVCAPLKPRADWTELKAFTKAMAETMAQEAPDTYVATI
TKAKRRGRILVDYLRNQRGSTAVAPYSARARAGAPVSMPIAWEELGEGMGPQHFTVLNAPARLANLSADPWADFRKAAAP
LPAGRTAGGTAGGKRRGGRR
>Mature_899_residues
GLSTYRAKRDFTVTPEPDGGAKGKARAAASASAGAYVIQKHAARRLHYDLRLEMDGVLKSWAVTRGPSLVPGEKRLAVHV
EDHPLAYGGFEGTIPEGQYGAGKVIVWDRGSWTPVGDPHKGYKKGHLEFALDGEKLHGRWHLVRMSPHPGDKKENWLLIK
VEDEAARPEGAPEITDEAPLSVVSGRDVEEVGAPSAAKSPKLSTAKTSRPKAAARDAKASEEAETTASGAERGARAVSAP
AKAKKTTAARVNGRSTRATAWDLPKGAKRAPLPDFLPPALATLARQAPKGRRYVHEIKFDGYRIAARLEDGEVRLLTRTG
LDWSARFGTAIREAAAALPVSDAMLDGEVVVEGGNGASDFSALQADLSEGRTDRFVYYAFDLLHLDGHDLTGAPLAERKA
LLEQLLTRAEGSGEGVLRYSGHFEDDGAMVLQHACRLSLEGVVSKLKDAPYHSGRSRDWIKSKCSERQEFVIGGFVPSTT
ARKAIGSLVLGVYEGKRLVHVGRVGTGFSNKMASDLHTLLAPEAVEESPFSARLTADEARGVTFVAPKRVAEVEFRAWTG
DGHLRHAAFRGLRDDKAAADVVREAASQPAETPKTPPKRRVRLTHPDRIYWPDAGVTKEGLADYYAEVWPRIAPFIVGRP
LALVRCPEGIEGQHFFQKHPWKGADKALKEVHDPKAPDEPPYLAVETLDGLMALVQGAALEIHPFGAPLSDWERPDLLTM
DLDPGEGVPWSAVIAAAHEVKARLETAGLAAFVKTSGGKGLHVCAPLKPRADWTELKAFTKAMAETMAQEAPDTYVATIT
KAKRRGRILVDYLRNQRGSTAVAPYSARARAGAPVSMPIAWEELGEGMGPQHFTVLNAPARLANLSADPWADFRKAAAPL
PAGRTAGGTAGGKRRGGRR

Specific function: Probably involved in the repair of DNA double-strand breaks by non-homologous-end joining (NHEJ) during spore germination [H]

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71985269, Length=327, Percent_Identity=24.4648318042813, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR014145
- InterPro:   IPR014143 [H]

Pfam domain/function: PF01068 DNA_ligase_A_M [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 97011; Mature: 96880

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS50160 DNA_LIGASE_A3 ; PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLSTYRAKRDFTVTPEPDGGAKGKARAAASASAGAYVIQKHAARRLHYDLRLEMDGVLK
CCCCCCCCCCCCEECCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHCEEEEEEHHHHHH
SWAVTRGPSLVPGEKRLAVHVEDHPLAYGGFEGTIPEGQYGAGKVIVWDRGSWTPVGDPH
HHHHCCCCCCCCCCCEEEEEECCCCEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCC
KGYKKGHLEFALDGEKLHGRWHLVRMSPHPGDKKENWLLIKVEDEAARPEGAPEITDEAP
CCCCCCCEEEEECCCEECCEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCC
LSVVSGRDVEEVGAPSAAKSPKLSTAKTSRPKAAARDAKASEEAETTASGAERGARAVSA
EEEECCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCHHHCC
PAKAKKTTAARVNGRSTRATAWDLPKGAKRAPLPDFLPPALATLARQAPKGRRYVHEIKF
CCHHHHHHHHEECCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEC
DGYRIAARLEDGEVRLLTRTGLDWSARFGTAIREAAAALPVSDAMLDGEVVVEGGNGASD
CCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHEECCEEEEECCCCCHH
FSALQADLSEGRTDRFVYYAFDLLHLDGHDLTGAPLAERKALLEQLLTRAEGSGEGVLRY
HHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEE
SGHFEDDGAMVLQHACRLSLEGVVSKLKDAPYHSGRSRDWIKSKCSERQEFVIGGFVPST
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCH
TARKAIGSLVLGVYEGKRLVHVGRVGTGFSNKMASDLHTLLAPEAVEESPFSARLTADEA
HHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCHHHCCCCCCEEEEHHHH
RGVTFVAPKRVAEVEFRAWTGDGHLRHAAFRGLRDDKAAADVVREAASQPAETPKTPPKR
CCEEEECCCCEEEEEEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHH
RVRLTHPDRIYWPDAGVTKEGLADYYAEVWPRIAPFIVGRPLALVRCPEGIEGQHFFQKH
CEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHCC
PWKGADKALKEVHDPKAPDEPPYLAVETLDGLMALVQGAALEIHPFGAPLSDWERPDLLT
CCCCHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEE
MDLDPGEGVPWSAVIAAAHEVKARLETAGLAAFVKTSGGKGLHVCAPLKPRADWTELKAF
EECCCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCEEEECCCCCCCCHHHHHHH
TKAMAETMAQEAPDTYVATITKAKRRGRILVDYLRNQRGSTAVAPYSARARAGAPVSMPI
HHHHHHHHHHHCCCCEEEHHHHHHHCCCEEEHHHHCCCCCEEECCCCCCCCCCCCEECCE
AWEELGEGMGPQHFTVLNAPARLANLSADPWADFRKAAAPLPAGRTAGGTAGGKRRGGRR
EHHHHCCCCCCCEEEEEECCHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GLSTYRAKRDFTVTPEPDGGAKGKARAAASASAGAYVIQKHAARRLHYDLRLEMDGVLK
CCCCCCCCCCCEECCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHCEEEEEEHHHHHH
SWAVTRGPSLVPGEKRLAVHVEDHPLAYGGFEGTIPEGQYGAGKVIVWDRGSWTPVGDPH
HHHHCCCCCCCCCCCEEEEEECCCCEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCC
KGYKKGHLEFALDGEKLHGRWHLVRMSPHPGDKKENWLLIKVEDEAARPEGAPEITDEAP
CCCCCCCEEEEECCCEECCEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCC
LSVVSGRDVEEVGAPSAAKSPKLSTAKTSRPKAAARDAKASEEAETTASGAERGARAVSA
EEEECCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCHHHCC
PAKAKKTTAARVNGRSTRATAWDLPKGAKRAPLPDFLPPALATLARQAPKGRRYVHEIKF
CCHHHHHHHHEECCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEC
DGYRIAARLEDGEVRLLTRTGLDWSARFGTAIREAAAALPVSDAMLDGEVVVEGGNGASD
CCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHEECCEEEEECCCCCHH
FSALQADLSEGRTDRFVYYAFDLLHLDGHDLTGAPLAERKALLEQLLTRAEGSGEGVLRY
HHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEE
SGHFEDDGAMVLQHACRLSLEGVVSKLKDAPYHSGRSRDWIKSKCSERQEFVIGGFVPST
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCH
TARKAIGSLVLGVYEGKRLVHVGRVGTGFSNKMASDLHTLLAPEAVEESPFSARLTADEA
HHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCHHHCCCCCCEEEEHHHH
RGVTFVAPKRVAEVEFRAWTGDGHLRHAAFRGLRDDKAAADVVREAASQPAETPKTPPKR
CCEEEECCCCEEEEEEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHH
RVRLTHPDRIYWPDAGVTKEGLADYYAEVWPRIAPFIVGRPLALVRCPEGIEGQHFFQKH
CEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHCC
PWKGADKALKEVHDPKAPDEPPYLAVETLDGLMALVQGAALEIHPFGAPLSDWERPDLLT
CCCCHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEE
MDLDPGEGVPWSAVIAAAHEVKARLETAGLAAFVKTSGGKGLHVCAPLKPRADWTELKAF
EECCCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCEEEECCCCCCCCHHHHHHH
TKAMAETMAQEAPDTYVATITKAKRRGRILVDYLRNQRGSTAVAPYSARARAGAPVSMPI
HHHHHHHHHHHCCCCEEEHHHHHHHCCCEEEHHHHCCCCCEEECCCCCCCCCCCCEECCE
AWEELGEGMGPQHFTVLNAPARLANLSADPWADFRKAAAPLPAGRTAGGTAGGKRRGGRR
EHHHHCCCCCCCEEEEEECCHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]